ADPT Up 22% in One Month: Is It Outperforming Its Rivals?

ADPT: Adaptive Biotechnologies logo
ADPT
Adaptive Biotechnologies

Here is how Adaptive Biotechnologies (ADPT) stacks up against its peers in size, valuation, growth and margin.

  • ADPT’s operating margin of -59.0% is negative, lower than most peers – trailing UTHR (50.1%).
  • ADPT’s revenue growth of 21.6% in the last 12 months is strong, outpacing VRTX, REGN, ALNY, UTHR but lagging MDGL.
  • ADPT gained 195.5% in the past year and trades at a PE of -16.3, outperforming its peers.

As a quick background, Adaptive Biotechnologies provides an immune medicine platform with immunosequencing technology for translational research, diagnostics, and drug discovery across life sciences and clinical applications.

  ADPT VRTX REGN ALNY MDGL UTHR
Market Cap ($ Bil) 2.0 101.4 62.0 58.9 9.2 14.1
Revenue ($ Bil) 0.2 11.4 14.2 2.3 0.5 3.1
PE Ratio -16.3 27.9 13.9 -218.5 -32.7 11.3
LTM Revenue Growth 21.6% 10.5% 5.4% 17.2% 3422.0% 17.6%
LTM Operating Margin -59.0% -1.7% 27.0% -4.9% -60.1% 50.1%
LTM FCF Margin -40.4% 30.6% 25.0% -3.2% -59.8% 34.8%
12M Market Return 195.5% -17.7% -50.2% 63.8% 66.8% -10.0%

Why does this matter? ADPT just went up 22% in a month – peer comparison puts stock performance, valuation, and financials in context – highlighting whether it is truly outperforming, lagging behind, and above all – can this continue? Read Buy or Sell ADPT Stock to see if Adaptive Biotechnologies holds up as a quality investment. Furthermore, there is always a risk of fall after a strong rally – see how the stock has dipped and recovered in the past through ADPT Dip Buyer Analysis lens.

While peer comparison is critical Trefis High Quality Portfolio evaluates much more, and is designed to reduce stock-specific risks while giving upside exposure.

Relevant Articles
  1. Stocks, Bonds, Gold, Crypto: Market Update 12/4/2025
  2. What’s Behind The 86% Surge in Wheaton Stock?
  3. Why Has Barrick Mining Stock Surged 154%?
  4. What Could Send Pfizer Stock Soaring
  5. What Can Trigger Intel Stock’s Slide?
  6. Cash Machine Trading Cheap – Iridium Communications Stock Set to Run?

Revenue Growth Comparison

  LTM 2024 2023 2022
ADPT 21.6% 5.1% -8.1% 20.1%
VRTX 10.5% 11.7% 10.5% 17.9%
REGN 5.4% 8.3% 7.8% -24.3%
ALNY 17.2% 23.0% 76.2% 22.9%
MDGL 3422.0% ∞%
UTHR 17.6% 23.6% 20.2% 14.9%

Operating Margin Comparison

  LTM 2024 2023 2022
ADPT -59.0% -86.8% -118.4% -108.0%
VRTX -1.7% -2.1% 38.3% 47.6%
REGN 27.0% 28.1% 30.9% 38.9%
ALNY -4.9% -7.9% -15.4% -75.7%
MDGL -60.1% -276.4%
UTHR 50.1% 50.3% 50.9% 50.6%

PE Ratio Comparison

  LTM 2024 2023 2022
ADPT -16.3 -5.5 -3.1 -5.4
VRTX 27.9 -193.9 29.0 22.3
REGN 13.9 17.4 23.7 17.8
ALNY -218.5 -108.0 -54.3 -25.6
MDGL -32.7 -14.1 -11.6 -16.8
UTHR 11.3 13.3 10.4 17.4

The Trefis High Quality (HQ) Portfolio, with a collection of 30 stocks, has a track record of comfortably outperforming its benchmark that includes all 3 – the S&P 500, S&P mid-cap, and Russell 2000 indices. Why is that? As a group, HQ Portfolio stocks provided better returns with less risk versus the benchmark index; less of a roller-coaster ride, as evident in HQ Portfolio performance metrics.