Y-mAbs Therapeutics (YMAB)
Market Price (9/30/2025): $8.6 | Market Cap: $389.7 MilSector: Health Care | Industry: Biotechnology
Y-mAbs Therapeutics (YMAB)
Market Price (9/30/2025): $8.6Market Cap: $389.7 MilSector: Health CareIndustry: Biotechnology
Investment Highlights
| Cash is significant % of market capNet D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -15% | Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -27 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -31% | |
| Valuation becoming less expensiveP/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -40% | Weak revenue growthRev Chg LTMRevenue Change % Last Twelve Months (LTM) is -1.3%, Rev Chg QQuarterly Revenue Change % is -14% | |
| Not cash flow generativeCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -21%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -21% | ||
| Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -10% |
| Cash is significant % of market capNet D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -15% |
| Valuation becoming less expensiveP/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -40% |
| Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -27 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -31% |
| Weak revenue growthRev Chg LTMRevenue Change % Last Twelve Months (LTM) is -1.3%, Rev Chg QQuarterly Revenue Change % is -14% |
| Not cash flow generativeCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -21%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -21% |
| Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -10% |
Market Valuation
| 9/30/25 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|
| Share Price CYE | $8.60 | $7.83 | $6.82 | $4.88 | $16.21 |
| Market Cap CYE ($ Mil) | 389.7 | 351.4 | 297.5 | 213.1 | 707.9 |
| Total Debt ($ Mil) | 3.1 | 0.8 | 1.4 | 1.8 | 3.6 |
| Total Cash ($ Mil) | 62.3 | 67.2 | 78.6 | 105.8 | 181.6 |
| Enterprise Value ($ Mil) | 330.6 | 352.2 | 298.9 | 214.9 | 711.5 |
| Valuation Ratios | |||||
| P/S TTM | 4.6 | 4.0 | 3.5 | 3.3 | 20.1 |
| P/EBIT TTM | -14.6 | -11.1 | -11.6 | -2.2 | -13.1 |
| P/E TTM | -17.5 | -11.7 | -13.9 | -2.2 | -12.7 |
| Sector Ratios | |||||
| P/S TTM (Sector) | 3.7 | 3.6 | 4.0 | 4.5 | 7.3 |
| P/EBIT TTM (Sector) | -1.6 | -1.3 | -1.4 | -1.3 | -2.8 |
| P/E TTM (Sector) | -1.9 | -1.5 | -1.5 | -1.3 | -2.8 |
| 9/30/25 | 2024 | 2023 | |
|---|---|---|---|
| Share Price CYE | $8.60 | $7.83 | $6.82 |
| Market Cap CYE ($ Mil) | 389.7 | 351.4 | 297.5 |
| Total Debt ($ Mil) | 3.1 | 0.8 | 1.4 |
| Total Cash ($ Mil) | 62.3 | 67.2 | 78.6 |
| Enterprise Value ($ Mil) | 330.6 | 352.2 | 298.9 |
| Valuation Ratios | |||
| P/S TTM | 4.6 | 4.0 | 3.5 |
| P/EBIT TTM | -14.6 | -11.1 | -11.6 |
| P/E TTM | -17.5 | -11.7 | -13.9 |
| Sector Ratios | |||
| P/S TTM (Sector) | 3.7 | 3.6 | 4.0 |
| P/EBIT TTM (Sector) | -1.6 | -1.3 | -1.4 |
| P/E TTM (Sector) | -1.9 | -1.5 | -1.5 |
Business Description
Y-mAbs Therapeutics, Inc., a commercial-stage biopharmaceutical company, focuses on the development and commercialization of novel antibody based therapeutic products for the treatment of cancer in the United States. It offers DANYELZA, a monoclonal antibody in combination with granulocyte-macrophage colony-stimulating factor for the treatment of pediatric patients with relapsed or refractory high-risk neuroblastoma. The company is also developing DANYELZA that is in Phase II clinical studies for the treatment of patients with first-line neuroblastoma, third-line neuroblastoma, and in relapsed osteosarcoma; GD2-GD3 vaccine that is in Phase II clinical trial for the treatment of Stage 4 high-risk neuroblastoma; and Omburtamab, a murine monoclonal antibody that is in clinical trials for the treatment of central nervous system/ leptomeningeal metastases from neuroblastoma, desmoplastic small round cell tumor, diffuse intrinsic pontine glioma, and other B7-H3 positive tumors.
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Price Returns Compared
Expand for Detailed View| 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total [1] | |
|---|---|---|---|---|---|---|---|
| Returns | |||||||
| YMAB Return | 58% | -67% | -70% | 40% | 15% | -100% | � |
| Peers Return | 1% | 8% | -9% | 4% | -11% | 12% | 2% |
| S&P 500 Return | 16% | 27% | -19% | 24% | 23% | 13% | 106% |
[1] Cumulative total returns since the beginning of 2020
[2] Peers: ACT, ALKS, PRGO, LIVN, PCRX.
[3] 2025 data is for the year up to 9/29/2025 (YTD)
Latest Trefis Analyses
Trade Ideas
Select past trade ideas related to YMAB and Biotechnology.
| Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
|---|---|---|---|---|---|---|---|
| 08312025 | LNTH | Lantheus | Dip Buy | DB | CFO/Rev | Low D/EDip Buy with High Cash Flow MarginsBuying dips for companies with significant cash flows from operations and reasonable debt / market cap | -7.8% | -7.8% | -8.7% |
| 08312025 | COO | Cooper Companies | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | 0.2% | 0.2% | -4.6% |
| 08312025 | WST | West Pharmaceutical Services | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | 5.9% | 5.9% | -1.3% |
| 07312025 | BMY | Bristol-Myers Squibb | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 1.9% | 1.9% | 0.0% |
| 07312025 | UTHR | United Therapeutics | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 57.5% | 57.5% | 0.0% |
| Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
|---|---|---|---|---|---|---|---|
| 08312025 | LNTH | Lantheus | Dip Buy | DB | CFO/Rev | Low D/EDip Buy with High Cash Flow MarginsBuying dips for companies with significant cash flows from operations and reasonable debt / market cap | -7.8% | -7.8% | -8.7% |
| 08312025 | COO | Cooper Companies | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | 0.2% | 0.2% | -4.6% |
| 08312025 | WST | West Pharmaceutical Services | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | 5.9% | 5.9% | -1.3% |
| 07312025 | BMY | Bristol-Myers Squibb | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 1.9% | 1.9% | 0.0% |
| 07312025 | UTHR | United Therapeutics | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 57.5% | 57.5% | 0.0% |
See Trefis Trade Ideas for more.
Research & Analysis
Invest in Strategies
Wealth Management
Peer Comparisons for Y-mAbs Therapeutics
Financials
| Median | |
|---|---|
| Name | |
| Mkt Price | 29.04 |
| Mkt Cap | 2.9 |
| Rev LTM | 1,268 |
| Op Inc LTM | 175 |
| FCF LTM | 209 |
| FCF 3Y Avg | 190 |
| CFO LTM | 291 |
| CFO 3Y Avg | 250 |
Growth & Margins
| Median | |
|---|---|
| Name | |
| Rev Chg LTM | 1.0% |
| Rev Chg 3Y Avg | 6.8% |
| Rev Chg Q | 0.4% |
| QoQ Delta Rev Chg LTM | 0.1% |
| Op Mgn LTM | 9.7% |
| Op Mgn 3Y Avg | 7.0% |
| QoQ Delta Op Mgn LTM | 0.3% |
| CFO/Rev LTM | 17.8% |
| CFO/Rev 3Y Avg | 16.9% |
| FCF/Rev LTM | 14.5% |
| FCF/Rev 3Y Avg | 14.1% |
Valuation
| Median | |
|---|---|
| Name | |
| Mkt Cap | 2.9 |
| P/S | 2.7 |
| P/EBIT | -3.1 |
| P/E | -11.3 |
| P/CFO | 8.4 |
| Total Yield | -3.6% |
| Dividend Yield | 0.0% |
| FCF Yield 3Y Avg | 6.6% |
| D/E | 0.1 |
| Net D/E | -0.1 |
Returns
| Median | |
|---|---|
| Name | |
| 1M Rtn | -5.0% |
| 3M Rtn | 4.9% |
| 6M Rtn | 2.0% |
| 12M Rtn | 5.5% |
| 3Y Rtn | 3.1% |
| 1M Excs Rtn | -8.1% |
| 3M Excs Rtn | -2.5% |
| 6M Excs Rtn | -17.6% |
| 12M Excs Rtn | -6.5% |
| 3Y Excs Rtn | -71.2% |
Earnings Returns History
Expand for More| Forward Returns | |||
|---|---|---|---|
| Earnings Date | 1D Returns | 5D Returns | 21D Returns |
| 8/8/2025 | -0.1% | -0.1% | 0.8% |
| 5/13/2025 | 2.2% | 2.5% | 21.1% |
| 3/4/2025 | -4.4% | -8.3% | -13.3% |
| 11/8/2024 | -0.5% | -25.5% | -34.0% |
| 8/12/2024 | -11.2% | 9.2% | 19.5% |
| 2/29/2024 | 11.9% | 5.6% | -3.1% |
| 11/13/2023 | 9.8% | 7.6% | 40.4% |
| 8/10/2023 | -9.9% | -12.2% | -16.1% |
| ... | |||
| SUMMARY STATS | |||
| # Positive | 11 | 12 | 13 |
| # Negative | 11 | 10 | 9 |
| Median Positive | 9.8% | 7.1% | 22.4% |
| Median Negative | -4.3% | -8.8% | -13.3% |
| Max Positive | 52.3% | 74.2% | 87.5% |
| Max Negative | -21.6% | -25.5% | -34.0% |
SEC Filings
Expand for More| Report Date | Filing Date | Filing |
|---|---|---|
| 6302025 | 8082025 | 10-Q 6/30/2025 |
| 3312025 | 5132025 | 10-Q 3/31/2025 |
| 12312024 | 3042025 | 10-K 12/31/2024 |
| 9302024 | 11082024 | 10-Q 9/30/2024 |
| 6302024 | 8122024 | 10-Q 6/30/2024 |
| 3312024 | 5072024 | 10-Q 3/31/2024 |
| 12312023 | 2292024 | 10-K 12/31/2023 |
| 9302023 | 11132023 | 10-Q 9/30/2023 |
| 6302023 | 8102023 | 10-Q 6/30/2023 |
| 3312023 | 5082023 | 10-Q 3/31/2023 |
| 12312022 | 3302023 | 10-K 12/31/2022 |
| 9302022 | 11072022 | 10-Q 9/30/2022 |
| 6302022 | 8082022 | 10-Q 6/30/2022 |
| 3312022 | 5092022 | 10-Q 3/31/2022 |
| 12312021 | 3012022 | 10-K 12/31/2021 |
| 9302021 | 11042021 | 10-Q 9/30/2021 |
Industry Resources
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