Roivant Sciences (ROIV)
Market Price (12/4/2025): $21.17 | Market Cap: $14.4 BilSector: Health Care | Industry: Biotechnology
Roivant Sciences (ROIV)
Market Price (12/4/2025): $21.17Market Cap: $14.4 BilSector: Health CareIndustry: Biotechnology
Investment Highlights
Why It Matters
Which of these 2 stories sounds closer for this stock?
1. Generates cash flow
The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.
2. Riding a trend
Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow
| Cash is significant % of market capNet D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -57% | Trading close to highsDist 52W High is -2.9%, Dist 3Y High is -2.9% | Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -1.2 Bil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -5105% |
| Low stock price volatilityVol 12M is 32% | Expensive valuation multiplesP/SPrice/Sales ratio is 330x | |
| Megatrend and thematic driversMegatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Biopharmaceutical R&D, Targeted Therapies, Show more. | Weak revenue growthRev Chg LTMRevenue Change % Last Twelve Months (LTM) is -36%, Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -23%, Rev Chg QQuarterly Revenue Change % is -73% | |
| Not cash flow generativeCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -3663%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -3696% | ||
| Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -11% |
| Cash is significant % of market capNet D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -57% |
| Low stock price volatilityVol 12M is 32% |
| Megatrend and thematic driversMegatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Biopharmaceutical R&D, Targeted Therapies, Show more. |
| Trading close to highsDist 52W High is -2.9%, Dist 3Y High is -2.9% |
| Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -1.2 Bil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -5105% |
| Expensive valuation multiplesP/SPrice/Sales ratio is 330x |
| Weak revenue growthRev Chg LTMRevenue Change % Last Twelve Months (LTM) is -36%, Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -23%, Rev Chg QQuarterly Revenue Change % is -73% |
| Not cash flow generativeCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -3663%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -3696% |
| Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -11% |
Valuation, Metrics & Events
ROIV Stock
Why The Stock Moved
Qualitative Assessment
AI Generated Analysis | Feedback
Roivant Sciences (ROIV) experienced a significant upward movement in its stock price from late August 2025 to early December 2025, driven by a series of positive clinical, financial, and legal developments. The stock was trading around $12.00 in late August 2025 (extrapolated based on overall movement and 52-week data) and reached approximately $20.70 by December 3, 2025, representing an increase of around 72.5%.
1. Positive Phase 3 VALOR Study Results for Brepocitinib in Dermatomyositis (DM)
On September 17, 2025, Roivant and Priovant announced positive Phase 3 VALOR study results for brepocitinib in dermatomyositis, demonstrating clinically meaningful and statistically significant improvement on the primary endpoint and all nine key secondary endpoints. This pivotal data is expected to lead to a New Drug Application (NDA) filing in the first half of calendar year 2026.
2. Durable Remission Data for IMVT-1402 in Graves' Disease
On September 3, 2025, Roivant unveiled durability and treatment-free six-month remission data for Immunovant's IMVT-1402 in uncontrolled Graves' disease, indicating a potentially disease-modifying outcome. This significant clinical finding further validates Roivant's pipeline.
Stock Movement Drivers
Return vs. Risk
Price Returns Compared
| 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total [1] | |
|---|---|---|---|---|---|---|---|
| Returns | |||||||
| ROIV Return | - | -1% | -21% | 41% | 5% | 70% | 98% |
| Peers Return | 6% | -1% | -7% | -13% | -25% | 2% | -34% |
| S&P 500 Return | 16% | 27% | -19% | 24% | 23% | 16% | 112% |
Monthly Win Rates [3] | |||||||
| ROIV Win Rate | 50% | 33% | 67% | 58% | 60% | ||
| Peers Win Rate | 29% | 21% | 25% | 27% | 15% | 40% | |
| S&P 500 Win Rate | 58% | 75% | 42% | 67% | 75% | 70% | |
Max Drawdowns [4] | |||||||
| ROIV Max Drawdown | - | -42% | -72% | -13% | -12% | -23% | |
| Peers Max Drawdown | -19% | -10% | -17% | -24% | -25% | -2% | |
| S&P 500 Max Drawdown | -31% | -1% | -25% | -1% | -2% | -15% | |
[1] Cumulative total returns since the beginning of 2020
[2] Peers: VRTX, ACSB, AIXC, ALPS, APRI.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 12/3/2025 (YTD)
How Low Can It Go
| Event | ROIV | S&P 500 |
|---|---|---|
| 2022 Inflation Shock | ||
| % Loss | -79.2% | -25.4% |
| % Gain to Breakeven | 381.1% | 34.1% |
| Time to Breakeven | 1217 days | 464 days |
| 2020 Covid Pandemic | ||
| % Loss | -4.8% | -33.9% |
| % Gain to Breakeven | 5.1% | 51.3% |
| Time to Breakeven | 34 days | 148 days |
Compare to VRTX, ACSB, AIXC, ALPS, APRI
In The Past
Roivant Sciences's stock fell -79.2% during the 2022 Inflation Shock from a high on 12/20/2021. A -79.2% loss requires a 381.1% gain to breakeven.
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Asset Allocation
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Latest Trefis Analyses
| Title | Topic | Date | |
|---|---|---|---|
| DASHBOARDS | |||
| Day 11 of Gains Streak for Roivant Sciences Stock with 17% Return (vs. 59% YTD) [10/27/2025] | Notification | ||
| How Low Can Roivant Sciences Stock Really Go? | Return | ||
| ROIV Dip Buy Analysis | |||
| Roivant Sciences (ROIV) Valuation Ratios Comparison | Financials | ||
| Roivant Sciences Total Shareholder Return (TSR): -4.3% in 2025 and 26.9% 3-yr compounded annual returns (above peer average) | |||
| Why You Shouldn Not Be Buying Roivant Sciences Stock | Buy or Fear | ||
| Fundamental Metrics: ... | |||
| ARTICLES | |||
| Mid Cap Stocks Trading At 52-Week High | November 11th, 2025 | ||
| Mid Cap Stocks Trading At 52-Week High | November 7th, 2025 | ||
| Roivant Sciences Stock Surges 17%, With A 11-Day Winning Spree | October 28th, 2025 | ||
| Mid Cap Stocks Trading At 52-Week High | September 18th, 2025 |
Trade Ideas
Select past ideas related to ROIV. For more, see Trefis Trade Ideas.
| Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
|---|---|---|---|---|---|---|---|
| 11142025 | CRL | Charles River Laboratories International | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 4.1% | 4.1% | -3.7% |
| 11142025 | GDRX | GoodRx | Dip Buy | DB | CFO/Rev | Low D/EDip Buy with High Cash Flow MarginsBuying dips for companies with significant cash flows from operations and reasonable debt / market cap | -9.8% | -9.8% | -11.8% |
| 11142025 | ASTH | Astrana Health | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 6.0% | 6.0% | -5.5% |
| 11142025 | SGRY | Surgery Partners | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 9.7% | 9.7% | -1.4% |
| 11072025 | TFX | Teleflex | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 6.2% | 6.2% | -5.1% |
| Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
|---|---|---|---|---|---|---|---|
| 11142025 | CRL | Charles River Laboratories International | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 4.1% | 4.1% | -3.7% |
| 11142025 | GDRX | GoodRx | Dip Buy | DB | CFO/Rev | Low D/EDip Buy with High Cash Flow MarginsBuying dips for companies with significant cash flows from operations and reasonable debt / market cap | -9.8% | -9.8% | -11.8% |
| 11142025 | ASTH | Astrana Health | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 6.0% | 6.0% | -5.5% |
| 11142025 | SGRY | Surgery Partners | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 9.7% | 9.7% | -1.4% |
| 11072025 | TFX | Teleflex | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 6.2% | 6.2% | -5.1% |
Research & Analysis
Invest in Strategies
Wealth Management
Peer Comparisons for Roivant Sciences
| Peers to compare with: |
Financials
| Median | |
|---|---|
| Name | |
| Mkt Price | 11.62 |
| Mkt Cap | 66.2 |
| Rev LTM | 23 |
| Op Inc LTM | -92 |
| FCF LTM | -6 |
| FCF 3Y Avg | -10 |
| CFO LTM | -6 |
| CFO 3Y Avg | -10 |
Growth & Margins
| Median | |
|---|---|
| Name | |
| Rev Chg LTM | -12.8% |
| Rev Chg 3Y Avg | -6.0% |
| Rev Chg Q | -30.9% |
| QoQ Delta Rev Chg LTM | -8.7% |
| Op Mgn LTM | -2,552.8% |
| Op Mgn 3Y Avg | -1,494.2% |
| QoQ Delta Op Mgn LTM | -635.2% |
| CFO/Rev LTM | -1,815.6% |
| CFO/Rev 3Y Avg | -1,211.9% |
| FCF/Rev LTM | -1,833.7% |
| FCF/Rev 3Y Avg | -1,221.9% |
Valuation
| Median | |
|---|---|
| Name | |
| Mkt Cap | 66.2 |
| P/S | 169.3 |
| P/EBIT | 8.0 |
| P/E | 5.8 |
| P/CFO | 9.0 |
| Total Yield | -1.4% |
| Dividend Yield | 0.0% |
| FCF Yield 3Y Avg | -4.1% |
| D/E | 0.0 |
| Net D/E | -0.3 |
Returns
| Median | |
|---|---|
| Name | |
| 1M Rtn | 7.2% |
| 3M Rtn | 40.6% |
| 6M Rtn | 44.3% |
| 12M Rtn | 36.1% |
| 3Y Rtn | 136.3% |
| 1M Excs Rtn | 7.2% |
| 3M Excs Rtn | 35.3% |
| 6M Excs Rtn | 29.5% |
| 12M Excs Rtn | 17.3% |
| 3Y Excs Rtn | 106.0% |
Returns Analyses
SEC Filings
Expand for More| Report Date | Filing Date | Filing |
|---|---|---|
| 6302025 | 8112025 | 10-Q 6/30/2025 |
| 3312025 | 5292025 | 10-K 3/31/2025 |
| 12312024 | 2102025 | 10-Q 12/31/2024 |
| 9302024 | 11122024 | 10-Q 9/30/2024 |
| 6302024 | 8092024 | 10-Q 6/30/2024 |
| 3312024 | 5302024 | 10-K 3/31/2024 |
| 12312023 | 2132024 | 10-Q 12/31/2023 |
| 9302023 | 11132023 | 10-Q 9/30/2023 |
| 6302023 | 8142023 | 10-Q 6/30/2023 |
| 3312023 | 6282023 | 10-K 3/31/2023 |
| 12312022 | 2132023 | 10-Q 12/31/2022 |
| 9302022 | 11142022 | 10-Q 9/30/2022 |
| 6302022 | 8152022 | 10-Q 6/30/2022 |
| 3312022 | 6282022 | 10-K 3/31/2022 |
| 12312021 | 2142022 | 10-Q 12/31/2021 |
| 9302021 | 11152021 | 10-Q 9/30/2021 |
Industry Resources
External Quote Links
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