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Myriad Genetics (MYGN)


Market Price (3/23/2026): $4.58 | Market Cap: $428.2 Mil
Sector: Health Care | Industry: Biotechnology

Myriad Genetics (MYGN)


Market Price (3/23/2026): $4.58
Market Cap: $428.2 Mil
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0 Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -36%
Weak multi-year price returns
2Y Excs Rtn is -106%, 3Y Excs Rtn is -148%
Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -68 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -8.2%
1 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Advanced Diagnostics, and Personalized Diagnostics.
Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 12%
Expensive valuation multiples
P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 238x
2   Weak revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is -1.6%, Rev Chg QQuarterly Revenue Change % is -0.4%
3   Not cash flow generative
FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -3.1%
4   Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -89%
5   Key risks
MYGN key risks include [1] persistent revenue declines and unprofitability, Show more.
0 Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -36%
1 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Advanced Diagnostics, and Personalized Diagnostics.
2 Weak multi-year price returns
2Y Excs Rtn is -106%, 3Y Excs Rtn is -148%
3 Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 12%
4 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -68 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -8.2%
5 Expensive valuation multiples
P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 238x
6 Weak revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is -1.6%, Rev Chg QQuarterly Revenue Change % is -0.4%
7 Not cash flow generative
FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -3.1%
8 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -89%
9 Key risks
MYGN key risks include [1] persistent revenue declines and unprofitability, Show more.

Valuation, Metrics & Events

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Myriad Genetics (MYGN) stock has lost about 40% since 11/30/2025 because of the following key factors:

1. Myriad Genetics experienced a significant revenue headwind due to UnitedHealthcare's discontinuation of coverage for its GeneSight mental health test, resulting in an $8.1 million impact on fourth-quarter 2025 revenue and a 15% year-over-year decline in Mental Health revenue for the full year 2025.

2. The company reported a substantial full-year 2025 GAAP net loss of $365.9 million, primarily driven by $319.4 million in impairments within its Mental Health and Women's Health segments. This highlighted ongoing profitability challenges and weighed on investor confidence.

Show more

Stock Movement Drivers

Fundamental Drivers

The -40.0% change in MYGN stock from 11/30/2025 to 3/22/2026 was primarily driven by a -39.7% change in the company's P/S Multiple.
(LTM values as of)113020253222026Change
Stock Price ($)7.634.58-40.0%
Change Contribution By: 
Total Revenues ($ Mil)825824-0.1%
P/S Multiple0.90.5-39.7%
Shares Outstanding (Mil)9394-0.4%
Cumulative Contribution-40.0%

LTM = Last Twelve Months as of date shown

Market Drivers

11/30/2025 to 3/22/2026
ReturnCorrelation
MYGN-40.0% 
Market (SPY)-4.8%24.8%
Sector (XLV)-7.8%1.2%

Fundamental Drivers

The -28.1% change in MYGN stock from 8/31/2025 to 3/22/2026 was primarily driven by a -26.6% change in the company's P/S Multiple.
(LTM values as of)83120253222026Change
Stock Price ($)6.374.58-28.1%
Change Contribution By: 
Total Revenues ($ Mil)833824-1.0%
P/S Multiple0.70.5-26.6%
Shares Outstanding (Mil)9294-1.1%
Cumulative Contribution-28.1%

LTM = Last Twelve Months as of date shown

Market Drivers

8/31/2025 to 3/22/2026
ReturnCorrelation
MYGN-28.1% 
Market (SPY)1.1%32.5%
Sector (XLV)6.2%18.6%

Fundamental Drivers

The -57.3% change in MYGN stock from 2/28/2025 to 3/22/2026 was primarily driven by a -55.4% change in the company's P/S Multiple.
(LTM values as of)22820253222026Change
Stock Price ($)10.734.58-57.3%
Change Contribution By: 
Total Revenues ($ Mil)838824-1.6%
P/S Multiple1.20.5-55.4%
Shares Outstanding (Mil)9194-2.8%
Cumulative Contribution-57.3%

LTM = Last Twelve Months as of date shown

Market Drivers

2/28/2025 to 3/22/2026
ReturnCorrelation
MYGN-57.3% 
Market (SPY)10.4%27.2%
Sector (XLV)-1.1%18.9%

Fundamental Drivers

The -75.8% change in MYGN stock from 2/28/2023 to 3/22/2026 was primarily driven by a -77.5% change in the company's P/S Multiple.
(LTM values as of)22820233222026Change
Stock Price ($)18.924.58-75.8%
Change Contribution By: 
Total Revenues ($ Mil)66182424.7%
P/S Multiple2.30.5-77.5%
Shares Outstanding (Mil)8194-13.7%
Cumulative Contribution-75.8%

LTM = Last Twelve Months as of date shown

Market Drivers

2/28/2023 to 3/22/2026
ReturnCorrelation
MYGN-75.8% 
Market (SPY)70.3%27.3%
Sector (XLV)19.6%21.6%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
MYGN Return40%-47%32%-28%-55%-23%-76%
Peers Return12%-35%12%28%30%1%38%
S&P 500 Return27%-19%24%23%16%-3%76%

Monthly Win Rates [3]
MYGN Win Rate50%25%50%50%33%33% 
Peers Win Rate63%37%45%55%57%60% 
S&P 500 Win Rate75%42%67%75%67%33% 

Max Drawdowns [4]
MYGN Max Drawdown0%-47%-4%-31%-72%-30% 
Peers Max Drawdown-14%-50%-21%-20%-20%-6% 
S&P 500 Max Drawdown-1%-25%-1%-2%-15%-3% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: EXAS, NTRA, LH, DGX, ILMN.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 3/20/2026 (YTD)

How Low Can It Go

Unique KeyEventMYGNS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-62.1%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven163.6%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-66.9%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven201.9%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven321 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-58.4%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven140.5%24.7%
2018 CorrectionTime to BreakevenTime to BreakevenNot Fully Recovered days120 days
2008 Global Financial Crisis2008 Global Financial Crisis  
2008 Global Financial Crisis% Loss% Loss-50.3%-56.8%
2008 Global Financial Crisis% Gain to Breakeven% Gain to Breakeven101.3%131.3%
2008 Global Financial CrisisTime to BreakevenTime to Breakeven2,186 days1,480 days

Compare to EXAS, NTRA, LH, DGX, ILMN

In The Past

Myriad Genetics's stock fell -62.1% during the 2022 Inflation Shock from a high on 9/1/2021. A -62.1% loss requires a 163.6% gain to breakeven.

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About Myriad Genetics (MYGN)

Myriad Genetics, Inc., a genetic testing and precision medicine company, develops and commercializes genetic tests in the United States and internationally. The company offers molecular diagnostic tests for use in oncology, and women's and mental health applications. It provides MyRisk Hereditary Cancer Test, a DNA sequencing test for assessing the risks for hereditary cancers; BRACAnalysis CDx Germline Companion Diagnostic Test, a DNA sequencing test to help determine the therapy for patients with metastatic breast, ovarian, metastatic pancreatic, or metastatic prostate cancer with deleterious or suspected deleterious germline BRCA variants; and MyChoice CDx Companion Diagnostic Test, a tumor test that determines homologous recombination deficiency status in patients with ovarian cancer. The company also offers Prolaris Prostate Cancer Prognostic Test, a RNA expression tumor analysis for assessing the aggressiveness of prostate cancer; EndoPredict Breast Cancer Prognostic Test, a RNA expression test for assessing the aggressiveness of breast cancer; Precise Tumor, a solution for precision oncology; and Prequel Prenatal Screen, a non-invasive prenatal screening test conducted using maternal blood to screen for severe chromosomal disorders in a fetus. In addition, it provides Foresight Carrier Screen, a prenatal test for future parents to assess their risk of passing on a recessive genetic condition to their offspring; and GeneSight Psychotropic Mental Health Medication Test, a DNA genotyping test to aid psychotropic drug selection for patients suffering from depression, anxiety, ADHD, and other mental health conditions. Myriad Genetics, Inc. has a strategic collaboration with Illumina, Inc. and Intermountain Precision Genomics for an offering of germline and somatic tumor testing services. The company was founded in 1991 and is headquartered in Salt Lake City, Utah.

AI Analysis | Feedback

  • A 23andMe for medical professionals, offering advanced genetic tests for critical health decisions in cancer, reproductive health, and mental well-being.
  • Like Quest Diagnostics or LabCorp, but specialized in cutting-edge genetic and molecular diagnostic tests that provide precise insights for oncology, women's health, and mental health treatment.

AI Analysis | Feedback

  • MyRisk Hereditary Cancer Test: A DNA sequencing test for assessing an individual's risk for hereditary cancers.
  • BRACAnalysis CDx Germline Companion Diagnostic Test: Helps determine therapy for patients with certain metastatic cancers who have specific germline BRCA variants.
  • MyChoice CDx Companion Diagnostic Test: A tumor test that identifies homologous recombination deficiency status in patients with ovarian cancer.
  • Prolaris Prostate Cancer Prognostic Test: Assesses the aggressiveness of prostate cancer through RNA expression tumor analysis.
  • EndoPredict Breast Cancer Prognostic Test: An RNA expression test for evaluating the aggressiveness of breast cancer.
  • Precise Tumor: A comprehensive solution designed for precision oncology.
  • Prequel Prenatal Screen: A non-invasive prenatal screening test performed on maternal blood to screen for severe chromosomal disorders in a fetus.
  • Foresight Carrier Screen: A prenatal test for future parents to assess their risk of passing on a recessive genetic condition to their offspring.
  • GeneSight Psychotropic Mental Health Medication Test: A DNA genotyping test that aids in psychotropic drug selection for patients with various mental health conditions.

AI Analysis | Feedback

Myriad Genetics (MYGN) primarily sells its genetic testing and precision medicine services for the benefit of individual patients. These services are typically ordered by healthcare professionals for their patients. Based on its diverse range of diagnostic tests and their applications, Myriad Genetics serves the following three primary categories of customers:

  • Oncology Patients: Individuals who require genetic testing for various cancer-related needs. This includes assessing the risk for hereditary cancers (e.g., with MyRisk), guiding therapy for patients with metastatic breast, ovarian, pancreatic, or prostate cancer (e.g., with BRACAnalysis CDx or MyChoice CDx), and determining the aggressiveness of prostate or breast cancer (e.g., with Prolaris or EndoPredict).
  • Women's Health Patients: Individuals in different stages of family planning or pregnancy. This category includes expectant mothers seeking non-invasive prenatal screening for chromosomal disorders in a fetus (Prequel Prenatal Screen) and future parents assessing their risk of passing on recessive genetic conditions to their offspring (Foresight Carrier Screen).
  • Mental Health Patients: Individuals suffering from mental health conditions such as depression, anxiety, or ADHD. For these patients, Myriad offers genetic testing (e.g., GeneSight Psychotropic Mental Health Medication Test) to aid healthcare providers in selecting more appropriate psychotropic medications based on an individual's genetic profile.

AI Analysis | Feedback

Illumina, Inc. (ILMN)

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Sam Raha, President and Chief Executive Officer

Sam Raha has served as President and Chief Executive Officer and a member of the board of directors at Myriad Genetics since April 2025. He joined Myriad in December 2023 as Chief Operating Officer. Prior to Myriad, he was President of Agilent's Diagnostics and Genomics Group and also served as Vice President of Global Marketing at Illumina. He holds an MBA from Santa Clara University and a bachelor's degree in molecular and cell biology from the University of California, Berkeley.

Ben Wheeler, Chief Financial Officer

Ben Wheeler was promoted to Chief Financial Officer, effective August 2025. He joined Myriad in December 2011 as assistant controller and has progressed through various financial leadership roles, including vice president, corporate controller; senior vice president, accounting; senior vice president, finance & treasury; and chief financial officer, operations. Before joining Myriad, he worked as an auditor for Ernst & Young. Mr. Wheeler holds both master's and bachelor's degrees in accounting from Brigham Young University and is a Certified Public Accountant.

Mark Verratti, Chief Operating Officer

Mark Verratti has served as Chief Operating Officer at Myriad Genetics since April 2025. Prior to this role, he was the Chief Commercial Officer. He joined Myriad Genetics in 2017 as President of Myriad's Mental Health business, which includes the GeneSight® pharmacogenomics test.

Brian Donnelly, Chief Commercial Officer

Brian Donnelly was appointed Chief Commercial Officer at Myriad Genetics in May 2025. In this role, he oversees global commercial strategy and execution. He brings over 20 years of leadership experience in diagnostics, genomics, and consumer health, having held prior roles at Ancestry, Amazon, Illumina, and GlaxoSmithKline. Mr. Donnelly holds an MBA and a J.D. from Rutgers University.

Dr. Patrick Burke, Executive Vice President of Innovation and Strategic Partnerships

Dr. Patrick Burke was promoted to Executive Vice President of Strategy and Innovation in May 2021. He is responsible for corporate development, Myriad's companion diagnostics business, digital strategy, and partnerships with large health systems and healthcare providers. Dr. Burke joined Myriad in 2001 and has more than 20 years of experience in the precision medicine and pharmaceutical industries.

AI Analysis | Feedback

Key Risks to Myriad Genetics (MYGN)

  • Intellectual Property Challenges and Expirations: Myriad Genetics heavily relies on its proprietary tests and methods, which are protected by patents. The expiration of key patents, or successful legal challenges to existing intellectual property rights, could open the door for increased competition from other companies offering similar genetic tests. This could lead to significant pricing pressure and erosion of market share, similar to the concept of a "patent cliff" in the pharmaceutical industry.
  • Reimbursement and Payer Coverage Changes: The success of Myriad's genetic tests is highly dependent on favorable reimbursement policies and coverage decisions by governmental and commercial payers. Changes in medical policy, decreases in reimbursement rates, or a reduction in covered indications for its molecular diagnostic tests could significantly impact the company's revenue and profitability.
  • Rapid Technological Advancements and Intense Competition: The genetic testing and precision medicine landscape is characterized by rapid technological innovation and a highly competitive environment. New sequencing technologies, advanced bioinformatics, and novel diagnostic approaches are continuously emerging. Myriad faces the ongoing risk that competitors could develop superior, more cost-effective, or more comprehensive tests, potentially rendering Myriad's current offerings less competitive or even obsolete if the company does not continually innovate and adapt.

AI Analysis | Feedback

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AI Analysis | Feedback

Myriad Genetics, Inc. (MYGN) operates in several key precision medicine markets, developing and commercializing genetic tests for oncology, women's health, and mental health applications. The addressable markets for its main products and services are significant, both in the U.S. and globally.

Oncology Portfolio (MyRisk Hereditary Cancer Test, BRACAnalysis CDx, MyChoice CDx, Prolaris Prostate Cancer Prognostic Test, EndoPredict Breast Cancer Prognostic Test, Precise Tumor)

  • Hereditary Cancer Testing Market (relevant to MyRisk Hereditary Cancer Test): The global hereditary cancer testing market was estimated at approximately USD 4.67 billion in 2024 and is projected to grow to about USD 14.45 billion by 2033, with a Compound Annual Growth Rate (CAGR) of 13.76% from 2025 to 2033. In the United States, this market was valued at approximately USD 1.93 billion in 2024 and is projected to reach USD 5.76 billion by 2033, demonstrating a CAGR of 13.3%.
  • Precision Oncology Market (relevant to Precise Tumor, BRACAnalysis CDx, MyChoice CDx, and other oncology tests): The global precision oncology market was valued at approximately USD 115.25 billion in 2024 and is expected to reach around USD 250.43 billion by 2034, growing at a CAGR of 8.07% from 2025 to 2034. The diagnostics segment within the precision oncology market is anticipated to exhibit significant growth. For the U.S. alone, the precision oncology market size was estimated at USD 38.9 billion in 2024 and is expected to reach about USD 84.52 billion by 2034, with a CAGR of 7.3%.
  • Breast Cancer Diagnostics Market (relevant to EndoPredict Breast Cancer Prognostic Test, MyChoice CDx, and BRACAnalysis CDx): The global breast cancer diagnostics market was estimated at approximately USD 5.86 billion in 2025 and is projected to reach USD 11.36 billion by 2033, growing at a CAGR of 8.8% from 2026 to 2033.
  • Prostate Cancer Testing Market (relevant to Prolaris Prostate Cancer Prognostic Test): The U.S. prostate cancer biomarkers market was valued at approximately USD 1.7 billion in 2024. The U.S. prostate cancer testing market is anticipated to reach USD 1,901.6 million in 2030 from USD 544.1 million in 2021, at a CAGR of 14.7% during the forecast period 2022-2030. The broader U.S. prostate cancer diagnostics market is expected to reach US$ 4,653.5 million by 2030, with a CAGR of 5.3% from 2024 to 2030.

Women's Health Portfolio (Prequel Prenatal Screen, Foresight Carrier Screen)

  • Non-Invasive Prenatal Screening (NIPS) / Non-Invasive Prenatal Testing (NIPT) Market (relevant to Prequel Prenatal Screen): The global NIPS/NIPT market was estimated at approximately US$ 3.68 billion in 2025 and is projected to reach US$ 5.91 billion by 2032, with a CAGR of 7.1% from 2026 to 2032. In the United States, this market generated approximately US$ 1.52 billion in 2023 and is expected to reach US$ 2.78 billion by 2030, growing at a CAGR of 9.1% from 2024 to 2030.
  • Carrier Screening Market (relevant to Foresight Carrier Screen): The global carrier screening market was valued at approximately USD 1.70 billion in 2025 and is projected to grow to USD 3.08 billion by 2034, exhibiting a CAGR of 6.4% during the forecast period. In the United States, the carrier screening market was valued at approximately USD 740.92 million in 2024 and is expected to reach USD 842.95 million in 2025.

Mental Health Portfolio (GeneSight Psychotropic Mental Health Medication Test)

  • Pharmacogenomics in Psychiatry/Depression Market (relevant to GeneSight Psychotropic Mental Health Medication Test): The global pharmacogenetics testing in psychiatry/depression market size was valued at approximately USD 1.34 billion in 2024 and is expected to reach USD 2.97 billion by 2032, at a CAGR of 10.4%. The U.S. pharmacogenetics testing in psychiatry/depression market held the largest revenue share within North America in 2024, accounting for 81.0% of the market. Myriad Genetics previously estimated the global market for GeneSight testing to be greater than $4 billion based on current and future indications.

AI Analysis | Feedback

Myriad Genetics (MYGN) anticipates several key drivers for future revenue growth over the next 2-3 years, stemming from strong performance in core areas, new product introductions, and strategic initiatives. Here are 3-5 expected drivers of future revenue growth: * Sustained Volume Growth in Core Oncology and Mental Health Tests: Myriad Genetics expects continued strong test volume increases in its core oncology and mental health franchises. Notably, tests like MyRisk Hereditary Cancer Test, GeneSight Psychotropic Mental Health Medication Test, and Prolaris Prostate Cancer Prognostic Test have demonstrated consistent year-over-year volume growth and are projected to continue gaining market share. * Launch of New and Expanded Products: The company plans to introduce multiple new and enhanced products in the coming years. Key launches anticipated in 2026 include an expanded MyRisk panel, an AI-enhanced Prolaris prostate cancer test, and Precise MRD for breast cancer. Additionally, new prenatal tests, such as FirstGene, are expected to enrich the product portfolio and drive future revenue. Myriad is also integrating Precise Tumor and Precise Liquid into its Precise Oncology Solutions platform. * Reacceleration of the Prenatal Testing Segment: Following past order management disruptions, Myriad Genetics is focused on rebuilding its prenatal segment and expects growth to reaccelerate in the coming quarters. The introduction of new prenatal tests like FirstGene is a part of this strategy. * Strategic Collaborations and Technology Enhancements: Myriad is engaging in strategic collaborations and integrating advanced technologies to enhance its offerings. An example is the partnership with Clairity and MagView to integrate Clairity's AI system with Myriad's MyRisk test to improve breast cancer risk assessment tools. This focus on technology and strategic partnerships is expected to bolster its competitive edge and drive revenue.

AI Analysis | Feedback

Share Repurchases

  • Myriad Genetics spent $0 on share buybacks in Q4 2019 and Q2 2026, indicating no significant share repurchases in recent years.

Share Issuance

  • In November 2023, Myriad Genetics announced an upsized public offering of 6,470,588 shares of common stock at $17.00 per share, generating approximately $110 million in gross proceeds.
  • As of March 4, 2026, Myriad Genetics registered a shelf to offer up to $200 million of common stock, preferred stock, depositary shares, debt securities, and/or warrants, providing authorization for future capital raises.
  • The number of shares outstanding increased from 78 million at the end of 2021 to 93.5 million as of March 13, 2026, reflecting recent share issuances.

Inbound Investments

  • In July 2025, the company secured a new $200 million term loan facility to enhance financial flexibility and support growth initiatives.
  • In January 2025, Myriad Genetics announced a five-year strategic alliance with The University of Texas MD Anderson Cancer Center to accelerate the clinical evaluation and development of its Precise MRD assay.
  • In September 2025, Myriad Genetics entered a strategic collaboration with SOPHiA GENETICS to develop and provide a global liquid biopsy companion diagnostic (CDx) test.

Outbound Investments

  • The most recent acquisition by Myriad Genetics was Gateway Genomics in November 2022 for $67.5 million, which develops a fetal development diagnostic genetic test.
  • In February 2024, Myriad Genetics acquired select assets, including the Precise™ Tumor Test, the Precise Liquid Test, and a CLIA-certified laboratory in St. George, Utah, from Intermountain Health's Intermountain Precision Genomics (IPG) laboratory business.

Capital Expenditures

  • Myriad Genetics invested $18.8 million in capital expenditures in Q4 2023.
  • Capital expenditures and capitalization of internal use software costs totaled $6.0 million in Q4 2025 and $6.9 million in Q2 2025.
  • The company forecasts annual capital expenditures to be between $20 million and $30 million, focusing on supporting its diagnostic testing capabilities, new product launches, and digital integration.

Better Bets vs. Myriad Genetics (MYGN)

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Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

MYGNEXASNTRALHDGXILMNMedian
NameMyriad G.Exact Sc.Natera Labcorp Quest Di.Illumina  
Mkt Price4.58104.91195.28263.00195.26124.33159.79
Mkt Cap0.419.927.021.721.118.920.5
Rev LTM8243,2472,30613,95211,0354,3433,795
Op Inc LTM-68-199-3101,5161,556816374
FCF LTM-26357761,2061,359931644
FCF 3Y Avg-83154-501,0591,044641398
CFO LTM24912151,6401,8861,079785
CFO 3Y Avg-39286351,5181,497798542

Growth & Margins

MYGNEXASNTRALHDGXILMNMedian
NameMyriad G.Exact Sc.Natera Labcorp Quest Di.Illumina  
Rev Chg LTM-1.6%17.7%35.9%7.2%11.8%-0.7%9.5%
Rev Chg 3Y Avg6.9%16.0%41.5%3.5%4.0%-1.8%5.5%
Rev Chg Q-0.4%23.1%39.8%5.6%7.1%5.0%6.3%
QoQ Delta Rev Chg LTM-0.1%5.4%8.9%1.4%1.7%1.3%1.5%
Op Mgn LTM-8.2%-6.1%-13.4%10.9%14.1%18.8%2.4%
Op Mgn 3Y Avg-12.6%-7.1%-22.6%9.6%13.8%9.0%0.9%
QoQ Delta Op Mgn LTM1.7%-1.1%3.2%1.0%-0.0%0.2%0.6%
CFO/Rev LTM0.2%15.1%9.3%11.8%17.1%24.8%13.4%
CFO/Rev 3Y Avg-5.2%9.7%-1.8%11.6%14.8%18.2%10.6%
FCF/Rev LTM-3.1%11.0%3.3%8.6%12.3%21.4%9.8%
FCF/Rev 3Y Avg-10.7%5.0%-6.6%8.1%10.3%14.6%6.5%

Valuation

MYGNEXASNTRALHDGXILMNMedian
NameMyriad G.Exact Sc.Natera Labcorp Quest Di.Illumina  
Mkt Cap0.419.927.021.721.118.920.5
P/S0.56.111.71.61.94.43.1
P/EBIT-1.1-109.2-102.316.313.215.96.1
P/E-1.2-95.7-129.824.821.322.210.0
P/CFO237.940.5125.513.211.217.529.0
Total Yield-85.4%-1.0%-0.8%5.1%6.4%4.5%1.9%
Dividend Yield0.0%0.0%0.0%1.1%1.7%0.0%0.0%
FCF Yield 3Y Avg-6.2%0.9%-1.1%5.4%6.1%3.1%2.0%
D/E0.50.10.00.30.30.10.2
Net D/E0.10.1-0.00.30.30.00.1

Returns

MYGNEXASNTRALHDGXILMNMedian
NameMyriad G.Exact Sc.Natera Labcorp Quest Di.Illumina  
1M Rtn6.8%1.4%-7.9%-6.7%-3.5%5.7%-1.1%
3M Rtn-30.1%3.0%-15.8%4.6%11.4%-7.8%-2.4%
6M Rtn-41.1%96.8%7.8%-4.7%7.3%21.0%7.6%
12M Rtn-54.2%130.0%29.2%13.5%19.0%41.8%24.1%
3Y Rtn-80.6%60.4%250.6%25.4%53.2%-41.0%39.3%
1M Excs Rtn9.7%6.7%-4.6%-1.5%1.6%8.8%4.2%
3M Excs Rtn-30.9%6.4%-10.2%6.3%12.7%-0.8%2.7%
6M Excs Rtn-38.5%97.7%10.5%-2.7%9.4%22.6%9.9%
12M Excs Rtn-68.5%114.9%14.8%-3.8%3.7%31.7%9.3%
3Y Excs Rtn-147.5%-4.2%175.2%-44.4%-11.0%-111.1%-27.7%

Comparison Analyses

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Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
Hereditary Cancer364328306  
Prenatal177151116  
Mental Health170138128  
Tumor Profiling126136129  
Autoimmune 00  
Other  0  
Other revenue  024 
Testing revenues   666 
Molecular diagnostic revenues    280
Pharmaceutical and clinical services revenue    20
Total838753678691300


Price Behavior

Price Behavior
Market Price$4.58 
Market Cap ($ Bil)0.4 
First Trading Date10/06/1995 
Distance from 52W High-54.2% 
   50 Days200 Days
DMA Price$5.21$6.11
DMA Trenddowndown
Distance from DMA-12.2%-25.0%
 3M1YR
Volatility52.4%87.9%
Downside Capture238.60180.74
Upside Capture81.9270.21
Correlation (SPY)27.0%26.4%
MYGN Betas & Captures as of 2/28/2026

 1M2M3M6M1Y3Y
Beta1.481.841.561.781.241.20
Up Beta1.462.041.682.601.231.03
Down Beta1.841.060.911.351.061.09
Up Capture-4%78%15%117%58%69%
Bmk +ve Days9203170142431
Stock +ve Days9152054113354
Down Capture274%309%293%198%140%111%
Bmk -ve Days12213054109320
Stock -ve Days12253968134392

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with MYGN
MYGN-51.1%87.3%-0.42-
Sector ETF (XLV)0.2%17.6%-0.1419.1%
Equity (SPY)15.8%18.9%0.6426.5%
Gold (GLD)48.2%27.0%1.458.1%
Commodities (DBC)17.8%17.4%0.8310.8%
Real Estate (VNQ)1.0%16.4%-0.1116.2%
Bitcoin (BTCUSD)-18.9%44.2%-0.3515.6%

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Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with MYGN
MYGN-30.9%61.5%-0.35-
Sector ETF (XLV)6.3%14.5%0.2628.9%
Equity (SPY)11.8%17.0%0.5437.3%
Gold (GLD)20.7%17.5%0.9712.5%
Commodities (DBC)10.9%19.0%0.468.7%
Real Estate (VNQ)2.8%18.8%0.0631.4%
Bitcoin (BTCUSD)4.8%56.7%0.3114.4%

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Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with MYGN
MYGN-18.4%64.5%-0.03-
Sector ETF (XLV)9.6%16.5%0.4730.8%
Equity (SPY)14.2%17.9%0.6835.6%
Gold (GLD)13.3%15.7%0.707.2%
Commodities (DBC)8.3%17.6%0.3911.9%
Real Estate (VNQ)5.0%20.7%0.2128.7%
Bitcoin (BTCUSD)66.9%66.8%1.0612.3%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date2272026
Short Interest: Shares Quantity11.6 Mil
Short Interest: % Change Since 21520267.9%
Average Daily Volume1.6 Mil
Days-to-Cover Short Interest7.2 days
Basic Shares Quantity93.5 Mil
Short % of Basic Shares12.4%

Earnings Returns History

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 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
1/12/2026-0.2%  
11/3/2025-21.0%-20.8%-10.4%
8/5/202546.5%55.8%75.5%
5/6/2025-41.3%-43.5%-32.3%
2/24/2025-14.8%-24.6%-29.4%
11/7/2024-1.5%-11.3%-15.8%
8/6/20242.6%8.6%6.5%
5/7/202421.1%28.2%12.7%
...
SUMMARY STATS   
# Positive101210
# Negative131012
Median Positive11.0%7.9%11.4%
Median Negative-5.4%-20.2%-13.4%
Max Positive46.5%55.8%75.5%
Max Negative-41.3%-43.5%-48.5%

SEC Filings

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Report DateFiling DateFiling
12/31/202502/24/202610-K
09/30/202511/04/202510-Q
06/30/202508/06/202510-Q
03/31/202505/07/202510-Q
12/31/202402/28/202510-K
09/30/202411/08/202410-Q
06/30/202408/07/202410-Q
03/31/202405/08/202410-Q
12/31/202302/28/202410-K
09/30/202311/07/202310-Q
06/30/202308/04/202310-Q
03/31/202305/04/202310-Q
12/31/202203/01/202310-K
09/30/202211/02/202210-Q
06/30/202208/05/202210-Q
03/31/202205/06/202210-Q

Insider Activity

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#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Phanstiel, S. Louise DirectBuy22720264.746,10028,890869,264Form
2Phanstiel, S. Louise DirectBuy22720264.8050,407242,1051,123,667Form
3Phanstiel, S. Louise DirectBuy22720264.6648,000223,7281,314,174Form
4Raha, Samraat SPresident and CEODirectBuy30920265.0040,000199,8442,463,597Form