Tearsheet

Inhibikase Therapeutics (IKT)


Market Price (2/25/2026): $2.03 | Market Cap: $182.8 Mil
Sector: Health Care | Industry: Biotechnology

Inhibikase Therapeutics (IKT)


Market Price (2/25/2026): $2.03
Market Cap: $182.8 Mil
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -42%
Weak multi-year price returns
2Y Excs Rtn is -49%, 3Y Excs Rtn is -122%
Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
1 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, and Neurodegenerative Disease Therapeutics.
  Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -53 Mil
2   Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -30%
3   Significant short interest
Short Interest Days-to-CoverDTC = (Short Interest Share Quantity) / (Average Daily Trading Volume). Reflects how many days it would take to cover (close out) the short interest based on average volumes. High DTC can signify an increased risk of a short squeeze. is 17.85
4   Key risks
IKT key risks include [1] the potential clinical failure of its lead drug candidate, Show more.
0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -42%
1 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, and Neurodegenerative Disease Therapeutics.
2 Weak multi-year price returns
2Y Excs Rtn is -49%, 3Y Excs Rtn is -122%
3 Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
4 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -53 Mil
5 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -30%
6 Significant short interest
Short Interest Days-to-CoverDTC = (Short Interest Share Quantity) / (Average Daily Trading Volume). Reflects how many days it would take to cover (close out) the short interest based on average volumes. High DTC can signify an increased risk of a short squeeze. is 17.85
7 Key risks
IKT key risks include [1] the potential clinical failure of its lead drug candidate, Show more.

Valuation, Metrics & Events

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Inhibikase Therapeutics (IKT) stock has gained about 40% since 10/31/2025 because of the following key factors:

1. Advancement of IKT-001 to a Global Pivotal Phase 3 Clinical Study in Pulmonary Arterial Hypertension (PAH). Inhibikase Therapeutics announced on November 20, 2025, its intention to advance IKT-001, a novel prodrug of imatinib mesylate, into a global pivotal Phase 3 clinical study for PAH, named IMPROVE-PAH, which is expected to commence in the first quarter of 2026. This significant progression in its lead investigational therapy followed positive feedback from the U.S. Food & Drug Administration (FDA) allowing for an immediate transition to a pivotal Phase 3 design from a previously planned Phase 2b study.

2. Accelerated Timeline for Potential FDA Approval. The revised study plan for IKT-001 in PAH, moving directly to a single pivotal Phase 3 study format, has the potential to accelerate the timeline to Phase 3 topline data readout and a possible New Drug Application (NDA) filing by approximately three years. This accelerated pathway to market for a critical therapy in a life-threatening condition significantly de-risks the development program and enhances the company's long-term value proposition.

Show more

Stock Movement Drivers

Fundamental Drivers

The 39.5% change in IKT stock from 10/31/2025 to 2/24/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)103120252242026Change
Stock Price ($)1.472.0539.5%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple∞∞0.0%
Shares Outstanding (Mil)90900.0%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

10/31/2025 to 2/24/2026
ReturnCorrelation
IKT39.5% 
Market (SPY)0.8%29.0%
Sector (XLV)9.4%22.6%

Fundamental Drivers

The 29.7% change in IKT stock from 7/31/2025 to 2/24/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)73120252242026Change
Stock Price ($)1.582.0529.7%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple∞∞0.0%
Shares Outstanding (Mil)9090-0.6%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

7/31/2025 to 2/24/2026
ReturnCorrelation
IKT29.7% 
Market (SPY)9.0%31.1%
Sector (XLV)21.6%30.9%

Fundamental Drivers

The -9.7% change in IKT stock from 1/31/2025 to 2/24/2026 was primarily driven by a -90.1% change in the company's Shares Outstanding (Mil).
(LTM values as of)13120252242026Change
Stock Price ($)2.272.05-9.7%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple∞∞0.0%
Shares Outstanding (Mil)990-90.1%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2025 to 2/24/2026
ReturnCorrelation
IKT-9.7% 
Market (SPY)15.2%34.6%
Sector (XLV)8.9%30.2%

Fundamental Drivers

The -51.6% change in IKT stock from 1/31/2023 to 2/24/2026 was primarily driven by a -95.3% change in the company's Shares Outstanding (Mil).
(LTM values as of)13120232242026Change
Stock Price ($)4.242.05-51.6%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple∞∞0.0%
Shares Outstanding (Mil)490-95.3%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2023 to 2/24/2026
ReturnCorrelation
IKT-51.6% 
Market (SPY)75.4%16.3%
Sector (XLV)23.9%14.4%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
IKT Return-79%-66%-58%156%-37%-12%-96%
Peers Return-26%-13%-15%-50%-32%2%-81%
S&P 500 Return27%-19%24%23%16%-0%82%

Monthly Win Rates [3]
IKT Win Rate42%25%42%50%42%50% 
Peers Win Rate33%58%54%38%56%50% 
S&P 500 Win Rate75%42%67%75%67%50% 

Max Drawdowns [4]
IKT Max Drawdown-80%-69%-73%-11%-57%-27% 
Peers Max Drawdown-37%-32%-42%-51%-49%-7% 
S&P 500 Max Drawdown-1%-25%-1%-2%-15%-1% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: VRTX, AKTS, ALPS, DCOY, DFTX.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 2/24/2026 (YTD)

How Low Can It Go

Unique KeyEventIKTS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-98.3%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven5788.9%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-30.3%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven43.5%51.3%
2020 Covid PandemicTime to BreakevenTime to BreakevenNot Fully Recovered days148 days

Compare to VRTX, AKTS, ALPS, DCOY, DFTX

In The Past

Inhibikase Therapeutics's stock fell -98.3% during the 2022 Inflation Shock from a high on 2/2/2021. A -98.3% loss requires a 5788.9% gain to breakeven.

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About Inhibikase Therapeutics (IKT)

Inhibikase Therapeutics, Inc., a clinical stage pharmaceutical company, develops therapeutics for Parkinson's Disease (PD) and related disorders that arise inside and outside of the brain. The company's product candidates include IkT-148009, a small molecule Abelson tyrosine kinase inhibitor for use in the treatment of PD, as well as gastrointestinal complications that arise as early symptoms of PD, such as swallowing, dysphagia, neurogenic constipation, and multiple system atrophy; and IkT-001Pro, a prodrug of the anti-cancer agent Imatinib that is in preclinical development to minimize gastrointestinal side effects and for the treatment of blood and stomach cancers. It is also involved in developing various research programs for other neurological diseases. The company has research and development collaborations with The Johns Hopkins University, Arizona State University, and Michigan State University, as well as Louisiana State University. Inhibikase Therapeutics, Inc. was founded in 2008 and is headquartered in Atlanta, Georgia.

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  • A biotech company aiming to be the Vertex Pharmaceuticals for Parkinson's disease.
  • A smaller, clinical-stage Biogen, but exclusively focused on developing a disease-modifying treatment for Parkinson's.

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  • IkT-148009: A lead drug candidate primarily developed to treat and potentially halt the progression of Parkinson's disease by inhibiting the c-Abl kinase.
  • IkT-007N1: A drug candidate designed to treat certain cancers, such as Philadelphia chromosome-positive leukemias and gastrointestinal stromal tumors, by inhibiting the c-Abl kinase.

AI Analysis | Feedback

Inhibikase Therapeutics (symbol: IKT) is a clinical-stage biopharmaceutical company focused on the development of treatments for neurodegenerative diseases, particularly Parkinson's disease.

As a clinical-stage company, Inhibikase Therapeutics does not currently have any commercial products approved for sale. Therefore, the company does not have "major customers" in the traditional sense that purchase its products, whether they be other companies or individual consumers.

The company is primarily engaged in research and development, conducting clinical trials for its lead product candidates. If and when its drug candidates receive regulatory approval, Inhibikase Therapeutics would typically sell its products through pharmaceutical distributors to healthcare providers, pharmacies, and hospitals, who would then dispense them to patients. At that future stage, its "customers" would be these larger distribution and healthcare entities, rather than individuals directly.

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Mark Iwicki, Chief Executive Officer
Mr. Iwicki has more than 30 years of experience in the biopharmaceutical industry. He previously served as Chief Executive Officer of KALA BIO, Civitas Therapeutics, and Sunovion Pharmaceuticals Inc. Additionally, he was President and Chief Executive Officer of Blend Therapeutics and President and Chief Operating Officer at Sepracor. Mr. Iwicki also held management positions at Novartis Pharmaceuticals Corporation, Astra Merck Inc., and Merck & Co.

David McIntyre, Chief Financial Officer
Mr. McIntyre has over two decades of executive experience in the life sciences sector, holding various C-suite roles at both public and private biotech and medical device entities, including Anthos Therapeutics, Inc., Tessa Therapeutics, Inc., and HeartWare International, Inc. He spent nearly ten years as a Partner at Apple Tree Partners, a multi-billion-dollar life sciences venture capital and growth equity fund, indicating a pattern of involvement with private equity-backed companies. Before entering the life sciences industry, he practiced as a senior attorney specializing in mergers and acquisitions, initial public offerings, and corporate law at Baker McKenzie and KPMG.

Chris Cabell, MD MHS FACC, President, Head of Research and Development, and Chief Medical Officer
Dr. Cabell previously served as Chief Executive Officer of CorHepta Pharmaceuticals, which was acquired by Inhibikase. He also held positions as Head of Clinical Development and Chief Medical Officer at Zura Bio and Emergent BioSolutions.

John Adams, PhD, Chief Scientific Officer
Dr. Adams was a co-founder and Chief Scientific Officer at CorHepta, joining Inhibikase from there. His prior roles include Senior Vice President of Discovery Biology at Iambic Therapeutics, Senior Vice President of Translational Science at Reneo Pharmaceuticals, and Head of Research at Arena Pharmaceuticals.

Timothy Pigot, Chief Commercial and Strategy Officer
Mr. Pigot has over three decades of experience in the pharmaceutical industry, encompassing both large pharma and startup organizations. Most recently, he served as Chief Commercial Officer of Aerovate Therapeutics. Previously, Mr. Pigot was Vice President of Marketing for MyoKardia, where he led the commercial launch strategy for mavacamten, a cardiac myosin inhibitor. He also held leadership positions in sales, marketing, and operations at Gilead Sciences and Pfizer.

AI Analysis | Feedback

The key risks to Inhibikase Therapeutics (IKT) are primarily associated with the inherent uncertainties of clinical drug development, ongoing legal scrutiny, and intense market competition.

  1. Clinical Development Risk: The most significant risk for Inhibikase Therapeutics is the potential failure of its lead drug candidate, IkT-001Pro, to demonstrate sufficient efficacy or an acceptable safety profile in ongoing and future clinical trials for Pulmonary Arterial Hypertension (PAH). The company has previously experienced a clinical failure with another candidate, risvodetinib, in Parkinson's disease, highlighting the inherent challenges in drug development. While IkT-001Pro aims to improve upon the safety and tolerability issues that hindered the approval of its active ingredient, imatinib, in PAH, its efficacy and safety in humans remain unproven. Clinical trials are inherently uncertain, with participants facing potential side effects ranging from mild to severe, and earlier phases carry higher levels of uncertainty regarding treatment effects. For example, a prior clinical hold was placed on IKT-148009 (risvodetinib) by the FDA due to safety concerns and the need for more comprehensive monitoring of potential vision-related adverse events.
  2. Shareholder Investigation and Corporate Governance Risk: Inhibikase Therapeutics is currently the subject of a shareholder investigation by Purcell & Lefkowitz LLP, which is examining potential breaches of fiduciary duty by the company's directors. This legal scrutiny introduces material risks, including the possibility of legal penalties, shareholder lawsuits, and reputational damage, all of which could significantly impede the company's clinical progress and financial stability. Issues such as allegations of overpriced executive compensation or a lack of transparency in decision-making could also deter potential investors.
  3. Competition: The competitive landscape within the Pulmonary Arterial Hypertension (PAH) market is intensifying. Notable competitors, such as Merck with its drug sotatercept, have demonstrated significant efficacy in PAH, setting a high bar for new treatments. This increasing competition poses a substantial external risk to the market potential and commercial success of IkT-001Pro, even if it proves to be clinically effective.

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The advancement of LRRK2 inhibitors, specifically Denali Therapeutics' DNL151 (in collaboration with Biogen), represents a clear emerging threat. Denali announced positive interim analysis from their Phase 2b LUMA study of DNL151 in Parkinson's Disease in September 2023, leading to its progression into Phase 3 clinical trials. DNL151 is designed as a disease-modifying therapy for Parkinson's Disease, directly competing with Inhibikase Therapeutics' lead candidate, IkT-148009, which is also a disease-modifying therapy for Parkinson's Disease and is currently in Phase 2 trials. The progression of a competitor's drug to a later clinical stage with positive data in the same indication and with a similar therapeutic goal constitutes a significant emerging competitive threat.

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Inhibikase Therapeutics (IKT) is developing product candidates for Parkinson's disease and Pulmonary Arterial Hypertension (PAH).

  • Parkinson's Disease (for product candidate IkT-148009/Risvodetinib): The global Parkinson's disease drugs market was valued at approximately USD 7.17 billion in 2024 and is projected to grow to about USD 13.46 billion by the end of 2032. North America held the largest share of this market, with approximately 34.86% in 2024, accounting for USD 2.50 billion.
  • Pulmonary Arterial Hypertension (PAH) (for product candidate IkT-001Pro): The global market for Pulmonary Arterial Hypertension is valued at approximately USD 7.7 billion annually.

AI Analysis | Feedback

Inhibikase Therapeutics (IKT), a clinical-stage biotechnology company, anticipates future revenue growth over the next 2-3 years to be primarily driven by the advancement and potential commercialization of its key drug candidates. As of current forecasts, the company is not expected to generate revenue from product sales in the immediate future, but significant milestones in its pipeline are critical precursors to future revenue streams. The expected drivers of future revenue growth for Inhibikase Therapeutics are: * Advancement and Positive Clinical Trial Outcomes for Risvodetinib (Risvo) in Parkinson's Disease (PD): Inhibikase's lead program, risvodetinib for Parkinson's disease, completed enrollment for its Phase 2 201 trial. Top-line data from this trial are expected in November 2024, with discussions with the FDA regarding Phase 3 plans anticipated by the end of 2024, and potential initiation of Phase 3 trials in Q1/Q2 2025. Successful progression through these stages is crucial for eventual market approval and revenue generation. * Advancement and Positive Clinical Trial Outcomes for IkT-001Pro in Pulmonary Arterial Hypertension (PAH): The company has received Investigational New Drug (IND) clearance from the FDA to proceed with a Phase 2b trial for IkT-001Pro in pulmonary arterial hypertension. Clinical development for this indication is projected to commence in late 2024 or early 2025, pending IND clearance. The global PAH market, valued at approximately $7.66 billion, represents a substantial commercial opportunity for IkT-001Pro, which is believed to offer an improved safety and tolerability profile compared to existing treatments. * Advancement and Potential Market Penetration of IkT-001Pro for Chronic Myeloid Leukemia (CML) with an Improved Safety Profile: Inhibikase Therapeutics has completed the pivotal phase of its 501 trial, evaluating the bioequivalence of IkT-001Pro with 400-milligram imatinib mesylate for CML. The company is considering further evaluation of bioequivalent doses with high-dose 600-milligram imatinib mesylate, aiming to demonstrate a potential safety benefit. High-dose imatinib mesylate is commonly used for CML but often poorly tolerated, a shortcoming that IkT-001Pro may overcome, potentially allowing it to capture market share. * Strategic Partnerships and Licensing Agreements: As a clinical-stage company, Inhibikase Therapeutics relies on significant investment for research and development. Securing strategic partnerships or licensing agreements for its pipeline assets could provide crucial non-dilutive funding, leverage the commercialization expertise and resources of larger pharmaceutical companies, and accelerate market access. Such agreements could generate revenue through upfront payments, milestone achievements, and future royalties, thereby fueling continued development and growth. The company also states that its multi-therapeutic pipeline for neurodegenerative diseases and its RAMPâ„¢ medicinal chemistry program for follow-on compounds could lead to additional development opportunities.

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Share Issuance

  • Inhibikase Therapeutics completed its Initial Public Offering (IPO) on December 23, 2020, issuing 1,800,000 shares of common stock at $10.00 per share, resulting in gross proceeds of $18 million.
  • On May 20, 2024, the company announced the pricing of a registered direct offering and warrant inducement, generating aggregate gross proceeds of $4.0 million.
  • In October 2024, Inhibikase Therapeutics announced a private offering of approximately $110 million, which included the sale of 58.31 million shares of common stock and pre-funded warrants for 21.985 million shares.

Inbound Investments

  • In October 2024, Inhibikase Therapeutics secured an aggregate investment of up to approximately $275 million from healthcare-focused investment funds, led by Soleus Capital.

Outbound Investments

  • On February 21, 2025, Inhibikase Therapeutics acquired CorHepta Pharmaceuticals for $15 million, which was paid through the issuance of 4,979,101 shares of Inhibikase Therapeutics common stock.

Capital Expenditures

  • In the last 12 months, capital expenditures for Inhibikase Therapeutics were approximately $4 million.
  • For the quarter ended June 30, 2025, purchases of equipment and improvements amounted to $13,399.

Latest Trefis Analyses

TitleDate
0DASHBOARDS 
1Inhibikase Therapeutics Earnings Notes12/16/2025
Title
0ARTICLES

Trade Ideas

Select ideas related to IKT.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
ABT_1302026_Insider_Buying_GTE_1Mil_EBITp+DE_V201302026ABTAbbott LaboratoriesInsiderInsider Buys | Low D/EStrong Insider Buying
Companies with strong insider buying in the last 1 month, positive operating income and reasonable debt / market cap
5.5%5.5%-1.0%
VEEV_1302026_Monopoly_xInd_xCD_Getting_Cheaper01302026VEEVVeeva SystemsMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-15.6%-15.6%-15.7%
BIIB_1162026_Dip_Buyer_FCFYield01162026BIIBBiogenDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
19.4%19.4%0.0%
BMRN_1162026_Dip_Buyer_FCFYield01162026BMRNBioMarin PharmaceuticalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
15.3%15.3%0.0%
DOCS_1162026_Dip_Buyer_High_CFO_Margins_ExInd_DE01162026DOCSDoximityDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-42.4%-42.4%-42.4%

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

IKTVRTXAKTSALPSDCOYDFTXMedian
NameInhibika.Vertex P.Aktis On.ALPS Decoy Th.Definium. 
Mkt Price2.05487.4320.000.930.7117.459.75
Mkt Cap0.2123.6----61.9
Rev LTM012,001--000
Op Inc LTM-534,554---6-104-29
FCF LTM-263,194---5-79-15
FCF 3Y Avg-211,832---12-65-16
CFO LTM-263,631---5-79-15
CFO 3Y Avg-202,225---12-65-16

Growth & Margins

IKTVRTXAKTSALPSDCOYDFTXMedian
NameInhibika.Vertex P.Aktis On.ALPS Decoy Th.Definium. 
Rev Chg LTM-8.9%----8.9%
Rev Chg 3Y Avg-10.4%----10.4%
Rev Chg Q-9.5%----9.5%
QoQ Delta Rev Chg LTM-2.4%----2.4%
Op Mgn LTM-37.9%----37.9%
Op Mgn 3Y Avg-24.7%----24.7%
QoQ Delta Op Mgn LTM-38.7%----38.7%
CFO/Rev LTM-30.3%----30.3%
CFO/Rev 3Y Avg-20.5%----20.5%
FCF/Rev LTM-26.6%----26.6%
FCF/Rev 3Y Avg-17.0%----17.0%

Valuation

IKTVRTXAKTSALPSDCOYDFTXMedian
NameInhibika.Vertex P.Aktis On.ALPS Decoy Th.Definium. 
Mkt Cap0.2123.6----61.9
P/S-10.3----10.3
P/EBIT-3.526.5----11.5
P/E-3.931.3----13.7
P/CFO-7.234.0----13.4
Total Yield-25.8%3.2%-----11.3%
Dividend Yield0.0%0.0%----0.0%
FCF Yield 3Y Avg-102.1%1.7%-----50.2%
D/E0.00.0----0.0
Net D/E-0.4-0.0-----0.2

Returns

IKTVRTXAKTSALPSDCOYDFTXMedian
NameInhibika.Vertex P.Aktis On.ALPS Decoy Th.Definium. 
1M Rtn17.8%4.1%-7.6%-4.0%-9.2%0.3%-1.9%
3M Rtn30.6%13.4%∞%-26.7%-13.6%15.9%13.4%
6M Rtn11.4%25.9%∞%-1.9%-13.6%15.9%11.4%
12M Rtn-17.3%1.2%158,630.2%-1.9%-13.6%15.9%-0.4%
3Y Rtn-52.2%69.6%457.1%-1.9%-13.6%15.9%7.0%
1M Excs Rtn18.2%4.4%-7.3%-3.6%-8.9%0.7%-1.5%
3M Excs Rtn28.6%10.0%∞%-3.1%-19.0%10.6%10.0%
6M Excs Rtn1.9%16.8%∞%-8.5%-20.2%9.4%1.9%
12M Excs Rtn-45.6%-13.9%195,963.8%-16.5%-28.2%1.4%-15.2%
3Y Excs Rtn-121.6%-1.5%336.6%-70.4%-82.1%-52.5%-61.4%

Comparison Analyses

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Financials

Segment Financials

Revenue by Segment
$ Mil20242023202220212020
Developing protein kinase inhibitor therapeutics 0311
Total 0311


Assets by Segment
$ Mil20242023202220212020
Developing protein kinase inhibitor therapeutics15    
Total15    


Price Behavior

Price Behavior
Market Price$2.05 
Market Cap ($ Bil)0.2 
First Trading Date12/23/2020 
Distance from 52W High-17.3% 
   50 Days200 Days
DMA Price$1.72$1.72
DMA Trenddownup
Distance from DMA19.4%19.4%
 3M1YR
Volatility78.7%81.1%
Downside Capture69.66207.63
Upside Capture230.20157.79
Correlation (SPY)21.4%34.6%
IKT Betas & Captures as of 1/31/2026

 1M2M3M6M1Y3Y
Beta2.061.171.551.971.471.05
Up Beta8.725.902.824.351.671.27
Down Beta-1.970.370.840.460.690.84
Up Capture-13%76%171%188%225%35%
Bmk +ve Days11223471142430
Stock +ve Days7202853103331
Down Capture730%93%156%198%147%106%
Bmk -ve Days9192754109321
Stock -ve Days13213366133387

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with IKT
IKT-33.9%82.7%-0.15-
Sector ETF (XLV)9.3%17.3%0.3531.0%
Equity (SPY)15.6%19.3%0.6335.0%
Gold (GLD)76.8%25.7%2.198.8%
Commodities (DBC)9.1%16.9%0.3512.0%
Real Estate (VNQ)7.9%16.6%0.2925.2%
Bitcoin (BTCUSD)-33.3%45.1%-0.7622.6%

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Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with IKT
IKT-47.0%96.4%-0.20-
Sector ETF (XLV)7.9%14.5%0.3612.6%
Equity (SPY)13.4%17.0%0.6216.3%
Gold (GLD)23.5%17.1%1.127.3%
Commodities (DBC)10.6%19.0%0.452.8%
Real Estate (VNQ)5.2%18.8%0.1812.9%
Bitcoin (BTCUSD)4.3%57.1%0.3012.1%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with IKT
IKT-28.9%96.4%-0.23-
Sector ETF (XLV)11.0%16.5%0.5512.8%
Equity (SPY)15.6%17.9%0.7516.8%
Gold (GLD)15.3%15.6%0.826.8%
Commodities (DBC)8.6%17.6%0.413.2%
Real Estate (VNQ)6.8%20.7%0.2913.1%
Bitcoin (BTCUSD)65.9%66.7%1.0512.1%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date1302026
Short Interest: Shares Quantity8.8 Mil
Short Interest: % Change Since 115202616.3%
Average Daily Volume0.5 Mil
Days-to-Cover Short Interest17.8 days
Basic Shares Quantity90.1 Mil
Short % of Basic Shares9.8%

Earnings Returns History

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 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
11/14/2025-0.7%-2.6%3.9%
8/14/20252.3%-1.8%-6.4%
3/27/2025-3.4%-16.7%-7.2%
11/17/20223.6%-3.6%-25.9%
4/1/2021-4.8%-9.8%-17.0%
SUMMARY STATS   
# Positive201
# Negative354
Median Positive3.0% 3.9%
Median Negative-3.4%-3.6%-12.1%
Max Positive3.6% 3.9%
Max Negative-4.8%-16.7%-25.9%

SEC Filings

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Report DateFiling DateFiling
09/30/202511/14/202510-Q
06/30/202508/14/202510-Q
03/31/202505/14/202510-Q
12/31/202403/27/202510-K
09/30/202411/14/202410-Q
06/30/202408/14/202410-Q
03/31/202405/15/202410-Q
12/31/202303/27/202410-K
09/30/202311/14/202310-Q
06/30/202308/14/202310-Q
03/31/202305/15/202310-Q
12/31/202203/31/202310-K
09/30/202211/14/202210-Q
06/30/202208/12/202210-Q
03/31/202205/16/202210-Q
12/31/202103/31/202210-K

Insider Activity

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#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Sands, Capital Life Sciences Pulse Fund Ii, Lp DirectBuy112420251.452,068,9652,999,99918,877,499Form