Greenwich LifeSciences (GLSI)
Market Price (3/30/2026): $21.95 | Market Cap: $299.4 MilSector: Health Care | Industry: Biotechnology
Greenwich LifeSciences (GLSI)
Market Price (3/30/2026): $21.95Market Cap: $299.4 MilSector: Health CareIndustry: Biotechnology
Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.
| Megatrend and thematic driversMegatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, Biopharmaceutical R&D, Show more. | Weak multi-year price returns2Y Excs Rtn is -7.9% | Very low revenueRev LTMTotal Revenue or Sales, Last Twelve Months is 0 |
| Meaningful short interestShort Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 10% | Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -20 Mil | |
| Stock price has recently run up significantly6M Rtn6 month market price return is 115%, 12M Rtn12 month market price return is 118% | ||
| Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -10% | ||
| Key risksGLSI key risks include [1] its total dependence on the successful clinical trial outcome and regulatory approval of its single product candidate, Show more. |
| Megatrend and thematic driversMegatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, Biopharmaceutical R&D, Show more. |
| Weak multi-year price returns2Y Excs Rtn is -7.9% |
| Meaningful short interestShort Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 10% |
| Very low revenueRev LTMTotal Revenue or Sales, Last Twelve Months is 0 |
| Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -20 Mil |
| Stock price has recently run up significantly6M Rtn6 month market price return is 115%, 12M Rtn12 month market price return is 118% |
| Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -10% |
| Key risksGLSI key risks include [1] its total dependence on the successful clinical trial outcome and regulatory approval of its single product candidate, Show more. |
Qualitative Assessment
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Greenwich LifeSciences (GLSI) stock has gained about 155% since 11/30/2025 because of the following key factors:
1. Significant Reduction in Breast Cancer Recurrence Rate in Phase III Trial.
Greenwich LifeSciences announced on March 17, 2026, a preliminary update from the fully enrolled, 250-patient, open-label non-HLA-A02 arm of its Phase III FLAMINGO-01 trial, showing a statistically significant 83% reduction in breast cancer recurrence rate (0.7% versus 4% annual recurrence rate, p < 0.005) over an average of 1.2 years of patient exposure, compared to a similar study. This positive clinical data indicated strong efficacy for GLSI-100 in preventing breast cancer recurrences. Further supporting this, the company announced on February 24, 2026, the acceptance of two abstracts at the AACR Annual Meeting 2026, including one detailing statistically significant delayed-type-hypersensitivity (DTH) immune response data from the open-label arm of FLAMINGO-01.
2. FDA Approval for Commercial Manufacturing of GP2.
On January 22, 2026, the FDA approved the use of commercially manufactured GP2 in the FLAMINGO-01 trial. This regulatory milestone is crucial as it de-risks future commercialization pathways for GLSI-100, demonstrating progress towards making the immunotherapy widely available after successful trial completion and potentially accelerating its market entry. The news triggered premarket gains exceeding 16%.
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1. Significant Reduction in Breast Cancer Recurrence Rate in Phase III Trial.
Greenwich LifeSciences announced on March 17, 2026, a preliminary update from the fully enrolled, 250-patient, open-label non-HLA-A02 arm of its Phase III FLAMINGO-01 trial, showing a statistically significant 83% reduction in breast cancer recurrence rate (0.7% versus 4% annual recurrence rate, p < 0.005) over an average of 1.2 years of patient exposure, compared to a similar study. This positive clinical data indicated strong efficacy for GLSI-100 in preventing breast cancer recurrences. Further supporting this, the company announced on February 24, 2026, the acceptance of two abstracts at the AACR Annual Meeting 2026, including one detailing statistically significant delayed-type-hypersensitivity (DTH) immune response data from the open-label arm of FLAMINGO-01.
2. FDA Approval for Commercial Manufacturing of GP2.
On January 22, 2026, the FDA approved the use of commercially manufactured GP2 in the FLAMINGO-01 trial. This regulatory milestone is crucial as it de-risks future commercialization pathways for GLSI-100, demonstrating progress towards making the immunotherapy widely available after successful trial completion and potentially accelerating its market entry. The news triggered premarket gains exceeding 16%.
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Stock Movement Drivers
Fundamental Drivers
The 155.8% change in GLSI stock from 11/30/2025 to 3/29/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).| (LTM values as of) | 11302025 | 3292026 | Change |
|---|---|---|---|
| Stock Price ($) | 8.73 | 22.33 | 155.8% |
| Change Contribution By: | |||
| Total Revenues ($ Mil) | 0 | 0 | 0.0% |
| P/S Multiple | ∞ | ∞ | 0.0% |
| Shares Outstanding (Mil) | 14 | 14 | 0.0% |
| Cumulative Contribution | 0.0% |
Market Drivers
11/30/2025 to 3/29/2026| Return | Correlation | |
|---|---|---|
| GLSI | 155.8% | |
| Market (SPY) | -5.3% | 48.4% |
| Sector (XLV) | -8.7% | 28.7% |
Fundamental Drivers
The 94.5% change in GLSI stock from 8/31/2025 to 3/29/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).| (LTM values as of) | 8312025 | 3292026 | Change |
|---|---|---|---|
| Stock Price ($) | 11.48 | 22.33 | 94.5% |
| Change Contribution By: | |||
| Total Revenues ($ Mil) | 0 | 0 | 0.0% |
| P/S Multiple | ∞ | ∞ | 0.0% |
| Shares Outstanding (Mil) | 13 | 14 | -2.0% |
| Cumulative Contribution | 0.0% |
Market Drivers
8/31/2025 to 3/29/2026| Return | Correlation | |
|---|---|---|
| GLSI | 94.5% | |
| Market (SPY) | 0.6% | 36.9% |
| Sector (XLV) | 5.2% | 19.9% |
Fundamental Drivers
The 82.7% change in GLSI stock from 2/28/2025 to 3/29/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).| (LTM values as of) | 2282025 | 3292026 | Change |
|---|---|---|---|
| Stock Price ($) | 12.22 | 22.33 | 82.7% |
| Change Contribution By: | |||
| Total Revenues ($ Mil) | 0 | 0 | 0.0% |
| P/S Multiple | ∞ | ∞ | 0.0% |
| Shares Outstanding (Mil) | 13 | 14 | -3.7% |
| Cumulative Contribution | 0.0% |
Market Drivers
2/28/2025 to 3/29/2026| Return | Correlation | |
|---|---|---|
| GLSI | 82.7% | |
| Market (SPY) | 9.8% | 27.9% |
| Sector (XLV) | -2.1% | 21.8% |
Fundamental Drivers
The 43.0% change in GLSI stock from 2/28/2023 to 3/29/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).| (LTM values as of) | 2282023 | 3292026 | Change |
|---|---|---|---|
| Stock Price ($) | 15.61 | 22.33 | 43.0% |
| Change Contribution By: | |||
| Total Revenues ($ Mil) | 0 | 0 | 0.0% |
| P/S Multiple | ∞ | ∞ | 0.0% |
| Shares Outstanding (Mil) | 13 | 14 | -6.0% |
| Cumulative Contribution | 0.0% |
Market Drivers
2/28/2023 to 3/29/2026| Return | Correlation | |
|---|---|---|
| GLSI | 43.0% | |
| Market (SPY) | 69.4% | 28.9% |
| Sector (XLV) | 18.4% | 21.9% |
Price Returns Compared
| 2021 | 2022 | 2023 | 2024 | 2025 | 2026 | Total [1] | |
|---|---|---|---|---|---|---|---|
| Returns | |||||||
| GLSI Return | -33% | -38% | -31% | 7% | 87% | 21% | -31% |
| Peers Return | -33% | -38% | -29% | -55% | -48% | 8% | -93% |
| S&P 500 Return | 27% | -19% | 24% | 23% | 16% | -5% | 72% |
Monthly Win Rates [3] | |||||||
| GLSI Win Rate | 42% | 50% | 25% | 50% | 42% | 33% | |
| Peers Win Rate | 31% | 44% | 44% | 36% | 50% | 53% | |
| S&P 500 Win Rate | 75% | 42% | 67% | 75% | 67% | 33% | |
Max Drawdowns [4] | |||||||
| GLSI Max Drawdown | -40% | -71% | -49% | -21% | -30% | -7% | |
| Peers Max Drawdown | -40% | -52% | -49% | -60% | -61% | -24% | |
| S&P 500 Max Drawdown | -1% | -25% | -1% | -2% | -15% | -5% | |
[1] Cumulative total returns since the beginning of 2021
[2] Peers: VRTX, AKTS, ALPS, DCOY, DFTX.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 3/27/2026 (YTD)
How Low Can It Go
| Event | GLSI | S&P 500 |
|---|---|---|
| 2022 Inflation Shock | ||
| % Loss | -86.7% | -25.4% |
| % Gain to Breakeven | 650.7% | 34.1% |
| Time to Breakeven | Not Fully Recovered days | 464 days |
Compare to VRTX, AKTS, ALPS, DCOY, DFTX
In The Past
Greenwich LifeSciences's stock fell -86.7% during the 2022 Inflation Shock from a high on 4/9/2021. A -86.7% loss requires a 650.7% gain to breakeven.
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About Greenwich LifeSciences (GLSI)
Greenwich LifeSciences, Inc., a clinical stage biopharmaceutical company, focuses on the development of novel cancer immunotherapies for breast cancer and other HER2/neu-expressing cancers. Its lead product candidate is the GP2, an immunotherapy, which has completed Phase IIb clinical trial to prevent breast cancer recurrences in patients who have previously undergone surgery. The company was formerly known as Norwell, Inc. and changed its name to Greenwich LifeSciences, Inc. in March 2018. Greenwich LifeSciences, Inc. was incorporated in 2006 and is headquartered in Stafford, Texas.
AI Analysis | Feedback
Here are 1-3 brief analogies to describe Greenwich LifeSciences (GLSI):
- It's like a small, highly focused Genentech working on new immunotherapies for breast cancer.
- Imagine a startup division of a major pharmaceutical like Merck or Roche, solely dedicated to developing immunotherapies for breast cancer.
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- GP2: An immunotherapy drug candidate in Phase IIb clinical trials for preventing breast cancer recurrence.
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Greenwich LifeSciences, Inc. (GLSI) is a clinical-stage biopharmaceutical company focused on the development of novel cancer immunotherapies. Its lead product candidate, GP2, has completed Phase IIb clinical trials. At this stage of development, the company is primarily engaged in research, development, and clinical trials, rather than commercial sales of a product.
Therefore, Greenwich LifeSciences (GLSI) does not currently have major customers in the traditional sense, as it is not yet selling a commercialized product to individuals or other companies. Its primary activities are focused on advancing its drug candidates through clinical trials and seeking regulatory approval, not on generating revenue from product sales.
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Creative Peptides
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Snehal S. Patel, Chief Executive Officer, Chief Financial Officer, and DirectorMr. Patel possesses over 30 years of experience in executive management, corporate development, operations, and investment banking within the healthcare industry. He has provided consulting, management, and advisory services for R&D and manufacturing design, scale-up, and operations at numerous public and private biotech companies, focusing on clinical and pre-clinical assets in areas such as stem cell therapy, multiple sclerosis t-cell therapy, oncolytic viruses, and disposable biotech manufacturing equipment. Prior to his current role, he served as an investment banker at Sanders Morris Harris, Ferghana Partners, and JP Morgan Chase, where his work centered on healthcare and biotech financing and strategic transactions. He also worked in operations and business development at consulting firms and at Bayer Corporation, specifically in the biotechnology division on the commercialization of recombinant Factor VIII and in Corporate Development involving licensing and M&A transactions. Mr. Patel frequently acquires company stock, indicating his confidence in Greenwich LifeSciences' future prospects.
F. Joseph Daugherty, M.D., Chief Medical Officer and Director
Dr. Daugherty brings over 35 years of experience in managing and overseeing biotechnology and biomedical projects. He is currently the Managing Partner of Phenolics, LLC and PharmaPrint, LLC, which are nutraceutical companies, and serves on the boards of several startup companies and a charitable foundation. Dr. Daugherty previously held positions as President, Chief Executive Officer, Chief Medical Officer, and Chairman of the board of directors at Eleos, Inc., a private, clinical-stage biotech company focused on anti-sense technology in cancer.
Jaye Thompson, M.S., Ph.D., Vice President, Clinical and Regulatory Affairs
Dr. Thompson holds the crucial role of Vice President, Clinical and Regulatory Affairs for Greenwich LifeSciences.
David B. McWilliams, Chairman of the Board
Mr. McWilliams has more than 40 years of experience in establishing biopharmaceutical and healthcare companies. He currently serves as the Chairman of the board of directors of BioHouston, Inc., an organization dedicated to advocating for Houston's life sciences industry. Mr. McWilliams has acted as a consultant and advisor at various levels for multiple private start-up biotech companies, assisting in the development of pre-clinical and clinical assets for cancer and other therapeutic areas. He was formerly the Chief Executive Officer of Greenwich LifeSciences. His career also includes roles as President of Harleco Diagnostics Division (EM Industries), General Manager and Program Manager of Abbott Laboratories, and Management Consultant at McKinsey & Company. He also served as Chief Executive Officer and President of Kallestad Diagnostics (Erbamont).
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The key risks to Greenwich LifeSciences (GLSI) are primarily associated with its stage of development as a clinical-stage biopharmaceutical company focused on a single lead product. *Clinical Trial and Regulatory Risk
Greenwich LifeSciences' success is heavily dependent on the successful completion of clinical trials and subsequent regulatory approval for its lead product candidate, GP2 (also referred to as GLSI-100), an immunotherapy for breast cancer. GP2 is currently in a Phase III clinical trial (FLAMINGO-01). Despite positive preliminary safety data from earlier phases and the ongoing Phase III trial, and the FDA's Fast Track designation, there is no guarantee of successful trial outcomes or market approval. Biopharmaceutical product development inherently carries a significant risk of failure at various stages of clinical trials, and regulatory requirements can be stringent and subject to change, potentially leading to delays or outright rejection. Manufacturing and pharmacy process concerns have also posed regulatory challenges in the past, though these have been addressed. *Financial Risk and Capital Constraints
As a clinical-stage company, Greenwich LifeSciences has a history of substantial losses and does not generate revenue from product sales, anticipating continued losses as it advances GP2 through development and towards commercialization. The company requires significant additional financing to fund its operations and complete the development and potential commercialization of its product candidate. Its existing cash reserves are expected to fund operations for a limited period, necessitating ongoing efforts to raise capital. The reliance on "at-the-market" share sales for funding can lead to shareholder dilution, and a failure to secure adequate additional funds could force the company to delay or reduce its development programs. *Concentration Risk
The company's business is highly concentrated on a single immunotherapy, GP2 (GLSI-100), as its primary product candidate. While Greenwich LifeSciences is exploring follow-on indications to expand the patient population and target other HER2/neu-expressing cancers, the entire pipeline strategy revolves around this single asset. This singular focus means that any setback, delay, or failure related to GP2 would have a severe and potentially catastrophic impact on the company's financial performance and future viability.AI Analysis | Feedback
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```htmlGreenwich LifeSciences' lead product candidate, GP2, an immunotherapy focused on preventing breast cancer recurrences in patients who have previously undergone surgery, targets HER2/neu-expressing cancers. The addressable markets for products and services related to breast cancer, particularly HER2-positive and HER2-low cancers, and cancer immunotherapies, are substantial.
- The global breast cancer therapeutics market was estimated at USD 31.5 billion in 2024 and is projected to reach USD 71.3 billion by 2034, growing at a Compound Annual Growth Rate (CAGR) of 8.5%. Another estimate places the global breast cancer market size at USD 26.23 billion in 2025, expected to grow to USD 38.54 billion by 2034 with a CAGR of 4.37%.
- The global HER2-positive breast cancer treatment market is estimated at USD 11.38 billion in 2026 and is projected to reach USD 13.79 billion by 2031, with a CAGR of 3.92%. North America accounted for 41.52% of this market's revenue in 2025.
- The global HER2 inhibitors market was valued at approximately USD 8.36 billion in 2025 and is expected to increase to approximately USD 13.69 billion by 2032, growing at a CAGR of 7.3%.
- The global cancer immunotherapy market was valued at USD 136.39 billion in 2025 and is projected to reach approximately USD 367.63 billion by 2035, growing at a CAGR of 10.42%. Within this, the breast cancer segment is anticipated to show significant growth.
- For HER2-low cancers, which GP2 also addresses (HER2 1-2+ patients), the market size across the 7 major markets (7MM) was approximately USD 3.2 billion in 2024. This market is projected to grow to USD 8.997 billion by 2034 in leading countries (US, EU4, UK, and Japan), at a CAGR of 11%. The United States market for HER2-low cancers was approximately USD 1.6 billion in 2024.
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The future revenue growth for Greenwich LifeSciences (GLSI) over the next 2-3 years is primarily driven by the advancement and potential commercialization of its lead product candidate, GP2 (GLSI-100), an immunotherapy aimed at preventing breast cancer recurrences.
- Successful Completion and Positive Data from the Phase III FLAMINGO-01 Clinical Trial: The ongoing global Phase III FLAMINGO-01 clinical trial evaluating GLSI-100 is a critical driver. The company expects to report topline efficacy and safety data once a prespecified number of recurrence events occurs, with a projected timeframe of 12 to 18 months, depending on event rates. Preliminary data from the non-HLA-A*02 arm of the trial have shown an approximately 80% reduction in recurrence rate after the primary immunization series. Positive outcomes from this trial are essential for subsequent regulatory submissions and potential market entry.
- Regulatory Approvals for GP2 (GLSI-100): The company is actively progressing toward filing a Biological License Application (BLA) with the FDA in the US and pursuing regulatory filings with European Medicines Agency (EMA) in Europe. The FDA's approval of the first commercially manufactured lot of GP2 vials for use in the Phase III trial has significantly de-risked the future BLA filing process from a manufacturing perspective. If approved, GLSI-100 could be granted up to 12 years of market exclusivity under current law.
- Commercial Manufacturing and Supply Chain Readiness: Greenwich LifeSciences has made substantial progress in establishing its commercial manufacturing capabilities. The company manufactured the first three commercial lots of GP2 active ingredient in 2023, capable of producing approximately 200,000 doses, and the first commercial lot of finished GP2 vials in 2024. This readiness in manufacturing and supply chain is crucial for a timely and efficient market launch following regulatory approval.
- Market Penetration Addressing Unmet Medical Need: Upon potential approval, GP2 is positioned to address a significant unmet need in preventing breast cancer recurrences, particularly in patients who do not adequately respond to existing treatments like Herceptin or Kadcyla. There are approximately 700,000 new breast cancer patients and 9.5 million breast cancer survivors in the US and EU in 2025. Successful market penetration within this patient population would be a key driver of revenue growth.
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Share Repurchases
- Greenwich LifeSciences suspended its share repurchase program in July 2022.
- Prior to suspension, the company repurchased approximately 520,000 shares of common stock for an aggregate of about $7.5 million.
Share Issuance
- Between January 1, 2024, and September 30, 2024, Greenwich LifeSciences raised approximately $1.75 million through an At-The-Market (ATM) agreement and nearly $2.5 million through a private placement offering.
- In the first three weeks of January 2026, the company raised approximately $7 million via its ATM financing vehicle.
- Cash burn in 2024 was offset in part through the sale of common stock via an ATM program and a private placement. The company also sold $1.2 million worth of shares in the ATM arrangement between January 1 and April 11, 2025.
Capital Expenditures
- Greenwich LifeSciences reported minimal to no significant capital expenditures on physical assets, with recent financial snapshots listing Capital Expenditures as $0.0.
- The primary focus of capital utilization is on research and development, particularly funding for its Phase III FLAMINGO-01 clinical trial.
- Research and development expenses increased to $2,292,040 for the three months ended September 30, 2024, up from $2,158,167 in the same quarter the previous year, mainly due to increased clinical expenses.
Trade Ideas
Select ideas related to GLSI.
| Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
|---|---|---|---|---|---|---|---|
| 02282026 | QDEL | QuidelOrtho | Insider | Insider Buys 45DStrong Insider BuyingCompanies with multiple insider buys in the last 45 days | 0.0% | 0.0% | 0.0% |
| 02272026 | CHE | Chemed | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 0.0% | 0.0% | 0.0% |
| 02272026 | LLY | Eli Lilly | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | 0.0% | 0.0% | 0.0% |
| 02202026 | HAE | Haemonetics | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 3.5% | 3.5% | 0.0% |
| 02132026 | IQV | IQVIA | Dip Buy | DB | P/E OPMDip Buy with Low PE and High MarginBuying dips for companies with tame PE and meaningfully high operating margin | 7.1% | 7.1% | -3.0% |
Research & Analysis
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Peer Comparisons
| Peers to compare with: |
Financials
| Median | |
|---|---|
| Name | |
| Mkt Price | 16.54 |
| Mkt Cap | 0.3 |
| Rev LTM | 0 |
| Op Inc LTM | -12 |
| FCF LTM | -7 |
| FCF 3Y Avg | -8 |
| CFO LTM | -7 |
| CFO 3Y Avg | -8 |
Growth & Margins
| Median | |
|---|---|
| Name | |
| Rev Chg LTM | 8.9% |
| Rev Chg 3Y Avg | 10.4% |
| Rev Chg Q | 9.5% |
| QoQ Delta Rev Chg LTM | 2.4% |
| Op Mgn LTM | 37.9% |
| Op Mgn 3Y Avg | 24.7% |
| QoQ Delta Op Mgn LTM | 38.7% |
| CFO/Rev LTM | 30.3% |
| CFO/Rev 3Y Avg | 20.5% |
| FCF/Rev LTM | 26.6% |
| FCF/Rev 3Y Avg | 17.0% |
Valuation
| Median | |
|---|---|
| Name | |
| Mkt Cap | 0.3 |
| P/S | 9.2 |
| P/EBIT | -0.0 |
| P/E | -0.1 |
| P/CFO | -0.1 |
| Total Yield | -6.4% |
| Dividend Yield | 0.0% |
| FCF Yield 3Y Avg | -4.3% |
| D/E | 0.0 |
| Net D/E | -0.0 |
Returns
| Median | |
|---|---|
| Name | |
| 1M Rtn | -16.1% |
| 3M Rtn | 1.0% |
| 6M Rtn | 12.3% |
| 12M Rtn | 12.1% |
| 3Y Rtn | 28.8% |
| 1M Excs Rtn | -7.4% |
| 3M Excs Rtn | 15.0% |
| 6M Excs Rtn | 17.0% |
| 12M Excs Rtn | 0.6% |
| 3Y Excs Rtn | -29.7% |
Price Behavior
Price Behavior
| Market Price | $22.33 | |
| Market Cap ($ Bil) | 0.3 | |
| First Trading Date | 09/25/2020 | |
| Distance from 52W High | -33.5% | |
| 50 Days | 200 Days | |
| DMA Price | $26.53 | $15.30 |
| DMA Trend | up | up |
| Distance from DMA | -15.8% | 46.0% |
| 3M | 1YR | |
| Volatility | 128.0% | 87.9% |
| Downside Capture | 2.83 | 1.59 |
| Upside Capture | 708.94 | 271.61 |
| Correlation (SPY) | 47.1% | 27.6% |
GLSI Betas & Captures as of 2/28/2026
[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
| 1M | 2M | 3M | 6M | 1Y | 3Y | |
|---|---|---|---|---|---|---|
| Beta | 5.75 | 6.19 | 5.96 | 2.93 | 1.12 | 1.32 |
| Up Beta | 8.61 | 6.83 | 5.99 | 1.41 | 0.48 | 0.99 |
| Down Beta | 6.87 | 4.55 | 6.05 | 3.22 | 0.87 | 1.30 |
| Up Capture | 538% | 1090% | 2087% | 875% | 524% | 394% |
| Bmk +ve Days | 9 | 20 | 31 | 70 | 142 | 431 |
| Stock +ve Days | 10 | 21 | 37 | 61 | 123 | 355 |
| Down Capture | 384% | 475% | 210% | 193% | 135% | 110% |
| Bmk -ve Days | 12 | 21 | 30 | 54 | 109 | 320 |
| Stock -ve Days | 11 | 20 | 24 | 63 | 124 | 391 |
[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
| Annualized Return | Annualized Volatility | Sharpe Ratio | Correlation with GLSI | |
|---|---|---|---|---|
| GLSI | 106.7% | 88.0% | 1.21 | - |
| Sector ETF (XLV) | 0.3% | 17.6% | -0.13 | 21.7% |
| Equity (SPY) | 14.5% | 18.9% | 0.59 | 27.7% |
| Gold (GLD) | 50.2% | 27.7% | 1.46 | -2.6% |
| Commodities (DBC) | 17.8% | 17.6% | 0.85 | 0.8% |
| Real Estate (VNQ) | 0.4% | 16.4% | -0.15 | 15.7% |
| Bitcoin (BTCUSD) | -23.7% | 44.2% | -0.49 | 26.7% |
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Based On 5-Year Data
| Annualized Return | Annualized Volatility | Sharpe Ratio | Correlation with GLSI | |
|---|---|---|---|---|
| GLSI | -6.6% | 80.0% | 0.26 | - |
| Sector ETF (XLV) | 6.0% | 14.5% | 0.23 | 19.3% |
| Equity (SPY) | 11.8% | 17.0% | 0.54 | 27.2% |
| Gold (GLD) | 20.7% | 17.7% | 0.96 | 1.9% |
| Commodities (DBC) | 11.6% | 18.9% | 0.50 | -0.6% |
| Real Estate (VNQ) | 3.0% | 18.8% | 0.07 | 19.8% |
| Bitcoin (BTCUSD) | 4.0% | 56.6% | 0.29 | 16.1% |
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Based On 10-Year Data
| Annualized Return | Annualized Volatility | Sharpe Ratio | Correlation with GLSI | |
|---|---|---|---|---|
| GLSI | 15.9% | 435.7% | 0.46 | - |
| Sector ETF (XLV) | 9.7% | 16.5% | 0.48 | 2.5% |
| Equity (SPY) | 14.0% | 17.9% | 0.67 | 2.5% |
| Gold (GLD) | 13.3% | 15.8% | 0.70 | -4.2% |
| Commodities (DBC) | 8.2% | 17.6% | 0.39 | -0.0% |
| Real Estate (VNQ) | 4.7% | 20.7% | 0.19 | 2.2% |
| Bitcoin (BTCUSD) | 66.4% | 66.8% | 1.06 | 3.5% |
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Earnings Returns History
Expand for More| Forward Returns | |||
|---|---|---|---|
| Earnings Date | 1D Returns | 5D Returns | 21D Returns |
| SUMMARY STATS | |||
| # Positive | 0 | 0 | 0 |
| # Negative | 0 | 0 | 0 |
| Median Positive | |||
| Median Negative | |||
| Max Positive | |||
| Max Negative | |||
SEC Filings
Expand for More| Report Date | Filing Date | Filing |
|---|---|---|
| 09/30/2025 | 11/14/2025 | 10-Q |
| 06/30/2025 | 08/14/2025 | 10-Q |
| 03/31/2025 | 05/20/2025 | 10-Q |
| 12/31/2024 | 04/15/2025 | 10-K |
| 09/30/2024 | 11/14/2024 | 10-Q |
| 06/30/2024 | 08/14/2024 | 10-Q |
| 03/31/2024 | 05/20/2024 | 10-Q |
| 12/31/2023 | 04/15/2024 | 10-K |
| 09/30/2023 | 10/19/2023 | 10-Q |
| 06/30/2023 | 08/21/2023 | 10-Q |
| 03/31/2023 | 05/22/2023 | 10-Q |
| 12/31/2022 | 03/31/2023 | 10-K |
| 09/30/2022 | 11/14/2022 | 10-Q |
| 06/30/2022 | 08/15/2022 | 10-Q |
| 03/31/2022 | 05/20/2022 | 10-Q |
| 12/31/2021 | 03/21/2022 | 10-K |
Insider Activity
Expand for More| # | Owner | Title | Holding | Action | Filing Date | Price | Shares | Transacted Value | Value of Held Shares | Form |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Patel, Snehal | CEO and CFO | Direct | Buy | 1052026 | 21.36 | 4,300 | 91,848 | 119,603,227 | Form |
| 2 | Patel, Snehal | CEO and CFO | Direct | Buy | 1022026 | 21.73 | 2,900 | 63,017 | 121,581,566 | Form |
| 3 | Patel, Snehal | CEO and CFO | Direct | Buy | 12192025 | 12.62 | 4,100 | 51,742 | 70,573,589 | Form |
| 4 | Patel, Snehal | CEO and CFO | Direct | Buy | 11282025 | 8.37 | 4,600 | 38,502 | 46,772,414 | Form |
| 5 | Patel, Snehal | CEO and CFO | Direct | Buy | 11122025 | 8.43 | 10,600 | 89,358 | 47,068,922 | Form |
Industry Resources
External Quote Links
| Y Finance | Barrons |
| TradingView | Morningstar |
| SeekingAlpha | ValueLine |
| Motley Fool | Robinhood |
| CNBC | Etrade |
| MarketWatch | Unusual Whales |
| YCharts | Perplexity Finance |
| FinViz |
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