Tearsheet

Cumberland Pharmaceuticals (CPIX)


Market Price (12/18/2025): $3.95 | Market Cap: $59.1 Mil
Sector: Health Care | Industry: Pharmaceuticals

Cumberland Pharmaceuticals (CPIX)


Market Price (12/18/2025): $3.95
Market Cap: $59.1 Mil
Sector: Health Care
Industry: Pharmaceuticals

Investment Highlights Why It Matters Which of these 2 stories sounds closer for this stock?

1. Generates cash flow

The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.

2. Riding a trend

Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow


0 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 17%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 13%
Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -3.3 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -7.9%
1 Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -27%
Weak revenue growth
Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is 0.4%, Rev Chg QQuarterly Revenue Change % is -8.7%
2 Attractive yield
FCF Yield is 9.5%
Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -9.8%
3 Megatrend and thematic drivers
Megatrends include Specialty Pharmaceutical Development. Themes include Niche Drug Development & Commercialization, Acute Care & Hospital Therapeutics, and Gastroenterology & Autoimmune Specialty Drugs.
High stock price volatility
Vol 12M is 140%
4  Key risks
CPIX key risks include [1] its reliance on the successful development and commercialization of its pipeline drug, Show more.
0 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 17%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 13%
1 Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -27%
2 Attractive yield
FCF Yield is 9.5%
3 Megatrend and thematic drivers
Megatrends include Specialty Pharmaceutical Development. Themes include Niche Drug Development & Commercialization, Acute Care & Hospital Therapeutics, and Gastroenterology & Autoimmune Specialty Drugs.
4 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -3.3 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -7.9%
5 Weak revenue growth
Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is 0.4%, Rev Chg QQuarterly Revenue Change % is -8.7%
6 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -9.8%
7 High stock price volatility
Vol 12M is 140%
8 Key risks
CPIX key risks include [1] its reliance on the successful development and commercialization of its pipeline drug, Show more.

Valuation, Metrics & Events

CPIX Stock


Why The Stock Moved


Qualitative Assessment

AI Generated Analysis | Feedback

Cumberland Pharmaceuticals (CPIX) experienced significant movements between August 31, 2025, and December 18, 2025. The stock price rose by 65.28% over two weeks leading up to December 16, 2025. Here are five key points explaining the stock's movement during the approximate period from August 31, 2025, to December 18, 2025:

1. Strong Q2 2025 Revenue Growth: On August 5, 2025, Cumberland Pharmaceuticals announced its Q2 2025 financial results, reporting combined net revenues of $10.8 million for the quarter, a 10% increase over the prior year period. Year-to-date revenues for the first six months of 2025 totaled $22.6 million, marking a 23% increase over the first half of 2024. This strong financial performance likely contributed positively to investor confidence.

2. Positive Ifetroban Clinical Study Results: In June 2025, breakthrough findings from Cumberland's Phase II FIGHT DMD trial for its ifetroban product candidate, evaluating it in patients with Duchenne muscular dystrophy (DMD), were presented. High-dose ifetroban demonstrated a 5.4% improvement in cardiac function in DMD patients, with additional biomarker data indicating reduced cardiac damage. These promising results, presented in August 2025, positioned ifetroban as a potential treatment for DMD cardiomyopathy and were submitted to the FDA for an end-of-Phase II meeting, generating significant positive sentiment.

Show more

Stock Movement Drivers

Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
CPIX Return-43%58%-52%-20%32%51%-31%
Peers Return-16%-0%-1%-32%-34%-2%-63%
S&P 500 Return16%27%-19%24%23%14%108%

Monthly Win Rates [3]
CPIX Win Rate25%50%33%50%42%50% 
Peers Win Rate46%42%38%44%40%44% 
S&P 500 Win Rate58%75%42%67%75%73% 

Max Drawdowns [4]
CPIX Max Drawdown-44%-25%-59%-36%-41%-20% 
Peers Max Drawdown-51%-35%-35%-55%-51%-40% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: HRTX, IRWD, PCRX, ASRT.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 12/17/2025 (YTD)

How Low Can It Go

Unique KeyEventCPIXS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-79.4%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven385.3%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-45.6%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven83.8%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven385 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-41.1%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven69.9%24.7%
2018 CorrectionTime to BreakevenTime to BreakevenNot Fully Recovered days120 days

Compare to LLY, JNJ, MRK, PFE, BMY


In The Past

Cumberland Pharmaceuticals's stock fell -79.4% during the 2022 Inflation Shock from a high on 12/6/2021. A -79.4% loss requires a 385.3% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth over time.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Cumberland Pharmaceuticals (CPIX)

Better Bets than Cumberland Pharmaceuticals (CPIX)

Trade Ideas

Select past ideas related to CPIX. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
16.3%16.3%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-7.1%-7.1%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
3.6%3.6%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
1.6%1.6%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
14.1%14.1%-5.1%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
16.3%16.3%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-7.1%-7.1%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
3.6%3.6%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
1.6%1.6%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
14.1%14.1%-5.1%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for Cumberland Pharmaceuticals

Peers to compare with:

Financials

CPIXHRTXIRWDPCRXASRTMedian
NameCumberla.Heron Th.Ironwood.Pacira B.Assertio  
Mkt Price3.891.273.3726.550.743.37
Mkt Cap0.10.20.51.20.10.2
Rev LTM41155339717137155
Op Inc LTM-3214460-172
FCF LTM6-31681241313
FCF 3Y Avg4-471391493535
CFO LTM7-30681411313
CFO 3Y Avg5-461401653535

Growth & Margins

CPIXHRTXIRWDPCRXASRTMedian
NameCumberla.Heron Th.Ironwood.Pacira B.Assertio  
Rev Chg LTM12.2%12.6%-10.4%3.1%9.2%9.2%
Rev Chg 3Y Avg0.4%16.6%-6.7%3.1%1.7%1.7%
Rev Chg Q-8.7%16.5%33.3%6.5%69.4%16.5%
QoQ Delta Rev Chg LTM-1.9%3.6%9.9%1.6%17.3%3.6%
Op Mgn LTM-7.9%1.0%42.4%8.4%-12.3%1.0%
Op Mgn 3Y Avg-17.2%-38.7%38.5%11.1%0.4%0.4%
QoQ Delta Op Mgn LTM-0.8%0.2%12.7%-1.4%15.5%0.2%
CFO/Rev LTM16.6%-19.5%20.0%19.7%9.7%16.6%
CFO/Rev 3Y Avg11.5%-35.3%35.1%23.8%22.6%22.6%
FCF/Rev LTM13.4%-20.1%20.0%17.3%9.7%13.4%
FCF/Rev 3Y Avg8.6%-36.1%35.0%21.6%22.5%21.6%

Valuation

CPIXHRTXIRWDPCRXASRTMedian
NameCumberla.Heron Th.Ironwood.Pacira B.Assertio  
Mkt Cap0.10.20.51.20.10.2
P/S1.41.41.61.60.61.4
P/EBIT-21.038.54.319.9-12.1
P/E-17.5-15.819.152.9-2.9-2.9
P/CFO8.5-7.18.18.06.48.0
Total Yield-5.7%-6.3%5.2%1.9%-34.1%-5.7%
Dividend Yield0.0%0.0%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg9.0%-28.2%21.9%16.0%-12.5%
D/E0.20.71.10.4-0.5
Net D/E-0.10.40.80.2-0.3

Returns

CPIXHRTXIRWDPCRXASRTMedian
NameCumberla.Heron Th.Ironwood.Pacira B.Assertio  
1M Rtn104.7%16.5%7.7%11.2%-1.7%11.2%
3M Rtn20.4%5.0%163.3%1.8%-22.1%5.0%
6M Rtn-27.4%-36.5%382.3%9.9%11.8%9.9%
12M Rtn83.5%-23.0%-4.5%33.9%-20.3%-4.5%
3Y Rtn71.4%-53.6%-72.1%-30.9%-79.9%-53.6%
1M Excs Rtn104.0%15.8%6.9%10.4%-2.4%10.4%
3M Excs Rtn16.2%-2.9%129.5%-1.7%-25.7%-1.7%
6M Excs Rtn-39.8%-48.9%369.9%-2.4%-0.5%-2.4%
12M Excs Rtn52.4%-31.7%-15.6%22.6%-30.9%-15.6%
3Y Excs Rtn10.8%-117.0%-140.7%-110.1%-148.7%-117.0%

Financials

Segment Financials

Revenue by Segment

$ Mil20242023202220212020
Kristalose1615161613
Vibativ9712119
Sancuso813   
Caldolor45555
Other revenue21122
Acetadote01124
Vaprisol0-0211
Omeclamox-Pak00-001
RediTrex-0-001 
Total4042363734


Price Behavior

Short Interest

Short Interest: As Of Date11282025
Short Interest: Shares Quantity24,522
Short Interest: % Change Since 11152025-28.0%
Average Daily Volume57,827
Days-to-Cover Short Interest1
Basic Shares Quantity14,958,534
Short % of Basic Shares0.2%