MRNA Stock Down -19% after 5-Day Loss Streak

MRNA: Moderna logo
MRNA
Moderna

Moderna (MRNA) stock hit day 5 of a continuous streak of days with losses, with cumulative losses over this period amounting to a -19% return. The company has lost about $2.0 Bil in value over the last 5 days, with its current market capitalization at about $11 Bil. The stock remains 33.6% below its value at the end of 2024. This compares with year-to-date returns of 6.1% for the S&P 500.

MRNA develops mRNA-based therapeutics and vaccines for infectious, immuno-oncology, rare, cardiovascular, and autoimmune diseases with 44 development programs, including 26 clinical trials across seven modalities. Is this drop a warning sign or a setup for rebound? Deep dive with Buy or Sell MRNA.

Comparing MRNA Stock Returns With The S&P 500

The following table summarizes the return for MRNA stock vs. the S&P 500 index over different periods, including the current streak:
 

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Return Period MRNA S&P 500
1D -6.6% -1.6%
5D (Current Streak) -19.2% -2.4%
1M (21D) -8.8% 0.2%
3M (63D) 2.1% 11.3%
YTD 2025 -33.6% 6.1%
2024 -58.2% 23.3%
2023 -44.6% 24.2%
2022 -29.3% -19.4%

 
What is the point? Sustained weakness can be more than noise. It often signals shifting sentiment or deeper concerns. A multi-day losing streak may warn of further downside, or present an opportunity to buy if fundamentals are intact. Take a look at what history tells you about whether past dips like this have been buying opportunities or traps: MRNA Dip Buyer Analysis.

Gains and Losses Streaks: S&P 500 Constituents

There are currently 13 S&P constituents with 3 days or more of consecutive gains and 188 constituents with 3 days or more of consecutive losses.
 

Consecutive Days # of Gainers # of Losers
3D 1 89
4D 10 33
5D 2 49
6D 0 4
7D or more 0 13
Total >=3 D 13 188

 
 
Key Financials for Moderna (MRNA)

Last 2 Fiscal Years:

Metric FY2023 FY2024
Revenues $6.8 Bil $3.2 Bil
Operating Income $-4.2 Bil $-3.9 Bil
Net Income $-4.7 Bil $-3.6 Bil

Last 2 Fiscal Quarters:

Metric 2024 FQ4 2025 FQ1
Revenues $956.0 Mil $107.0 Mil
Operating Income $-1.2 Bil $-1.0 Bil
Net Income $-1.1 Bil $-971.0 Mil

 
The losing streak MRNA stock is currently on doesn’t inspire much confidence among investors. In contrast, Trefis High Quality (HQ) Portfolio, with a collection of 30 stocks, has a track record of comfortably outperforming the S&P 500 over the last 4-year period. Why is that? As a group, HQ Portfolio stocks provided better returns with less risk versus the benchmark index; less of a roller-coaster ride, as evident in HQ Portfolio performance metrics.