How Does Thermo Fisher Scientific Stock Stack Up Against Its Peers?

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Thermo Fisher Scientific (TMO) stock has delivered mixed performance over the past year, posting a -2.12% return. Against peers like DHR, A, ILMN, BDX, and WAT, TMO, as of 2/27/2026, demonstrates solid operating margins of 18.79% and steady LTM revenue growth of 3.91%. However, its PE ratio of 29.25 suggests a relatively elevated valuation, and its free cash flow generation, while solid, trails some top-tier rivals like DHR (21.4%) and ILMN (21.4%), potentially limiting significant near-term upside.

  • TMO’s 18.4% operating margin, strong but below WAT’s 26.5%, suggests WAT benefits more from high-margin specialized analytical consumables.
  • TMO’s 3.2% revenue growth trails A, BDX, WAT, possibly diluted by broad offerings versus peers’ specific high-demand product cycles.
  • TMO’s 0.1% stock drop (PE 30.0) underperforms DHR/ILMN, possibly due to DHR’s stable recurring revenue and ILMN’s genomics market acceleration.

Here’s how Thermo Fisher Scientific stacks up across size, valuation, and profitability versus key peers.

  TMO DHR A ILMN BDX WAT
Market Cap ($ Bil) 197.0 149.0 34.1 20.4 50.4 19.0
Revenue ($ Bil) 43.7 24.6 6.9 4.3 21.9 3.1
PE Ratio 30.0 41.2 26.2 24.0 28.7 29.3
LTM Revenue Growth 3.2% 2.9% 6.7% -0.7% 6.2% 6.9%
LTM Operating Margin 18.4% 19.1% 21.3% 18.8% 14.2% 26.5%
LTM FCF Margin 14.0% 21.4% 16.6% 21.4% 12.0% 19.4%
12M Market Return -0.1% 3.0% -3.7% 51.1% -19.6% -14.4%

For more details on Thermo Fisher Scientific, read Buy or Sell TMO Stock. Below we compare TMO’s growth, margin, and valuation with peers across years

Trefis: TMO Stock Insights

Revenue Growth Comparison

  LTM 2025 2024 2023 2022
TMO 3.2% – 0.1% -4.6% 14.5%
DHR 2.9% 2.9% -0.1% -10.3%  
A 6.7% 6.7% -4.7% -0.2%  
ILMN -0.7% -0.7% -2.9% -1.7%  
BDX 6.2% 8.2% 4.2% 2.7%  
WAT 6.9% – 0.1% -0.5% 6.7%

Operating Margin Comparison

  LTM 2025 2024 2023 2022
TMO 18.4% – 18.0% 17.1% 18.9%
DHR 19.1% 19.1% 20.4% 21.8%  
A 21.3% 21.3% 22.9% 19.8%  
ILMN 18.8% 18.8% 13.7% -4.9%  
BDX 14.2% 13.7% 14.2% 12.5%  
WAT 26.5% – 28.3% 27.7% 29.7%

PE Ratio Comparison

  LTM 2025 2024 2023 2022
TMO 30.0 – 34.9 33.5 29.9
DHR 41.2 45.1 43.0 35.8  
A 26.2 29.7 30.2 33.0  
ILMN 24.0 23.9 -17.4 -18.4  
BDX 28.7 33.3 38.6 47.0  
WAT 29.3 – 35.3 34.1 27.9

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