Market Movers | Winners: BBNX, EMAT, BRUN | Losers: PALI, ALHC, JBHT
A split market shows extreme moves in individual stocks, but persistence is rare among the leaders.
The S&P 500 returned -0.4% and the Dow Jones Industrial Average returned -1.2%, while the Nasdaq-100 returned +0.0%. Amid the mixed index performance, single stocks saw sharp moves, with Palisade Bio (PALI) falling 16.1%. The key question is whether any of today’s volatility signals a durable trend or is simply noise. The day’s largest moves are below.
Wednesday’s Market Winners
The 10 US-listed stocks in the Trefis coverage universe with the highest returns on the last trading day:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | BBNX | Beta Bionics | 15.3% | -27.2% |
| 2 | EMAT | Evolution Metals & Technologies | 14.8% | n/a |
| 3 | BRUN | Boost Run | 11.7% | n/a |
| 4 | AXTI | AXT | 11.4% | 293.3% |
| 5 | ARQT | Arcutis Biotherapeutics | 11.2% | -10.0% |
| 6 | SMTC | Semtech | 11.0% | 127.4% |
| 7 | SABR | Sabre | 11.0% | 70.6% |
| 8 | CIFR | Cipher Digital | 10.8% | 13.3% |
| 9 | EROC | ERock | 10.6% | n/a |
| 10 | CYPH | Cypherpunk Technologies | 9.9% | 110.3% |
Wednesday’s Market Losers
And the 10 US-listed stocks in the Trefis coverage universe with the lowest returns:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | PALI | Palisade Bio | -16.1% | -28.1% |
| 2 | ALHC | Alignment Healthcare | -16.0% | -55.9% |
| 3 | JBHT | JB Hunt Transport Services | -13.3% | 22.5% |
| 4 | INDP | Indaptus Therapeutics | -11.8% | 10.3% |
| 5 | BTGO | BitGo | -11.6% | n/a |
| 6 | RCAT | Red Cat | -10.9% | -10.5% |
| 7 | EIKN | Eikon Therapeutics | -10.3% | n/a |
| 8 | PLSE | Pulse Biosciences | -10.1% | 261.3% |
| 9 | ON | ON Semiconductor | -9.0% | 23.0% |
| 10 | HPK | HighPeak Energy | -8.9% | 66.0% |
One name shows strength beyond a single day.
Most large moves are fleeting, but Cypherpunk Technologies (CYPH) appears on both the one-day and one-month winners lists. Its one-month return is +246.0%. This is not the result of a single session’s gain. Excluding today, the stock still gained +214.8% over the other sessions in that period.
Movers Over The Last Week
Widening the window to five trading days, these are the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | INDP | Indaptus Therapeutics | 54.3% | 10.3% |
| 2 | ACVA | ACV Auctions | 41.4% | 29.9% |
| 3 | BBNX | Beta Bionics | 27.3% | -27.2% |
| 4 | SDGR | Schrodinger | 24.6% | 33.8% |
| 5 | MYGN | Myriad Genetics | 21.0% | -37.2% |
| 6 | ELMT | Elmet | 20.5% | n/a |
| 7 | NTSK | Netskope | 19.6% | -1.4% |
| 8 | S | SentinelOne | 19.2% | 54.5% |
| 9 | BALY | Ballys | 18.9% | -36.1% |
| 10 | FTRE | Fortrea | 18.9% | 15.8% |
Losers
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | ALHC | Alignment Healthcare | -33.2% | -55.9% |
| 2 | SWMR | Swarmer | -28.9% | n/a |
| 3 | ALM | Almonty Industries | -26.5% | 52.9% |
| 4 | LEU | Centrus Energy | -23.4% | -42.7% |
| 5 | SMR | NuScale Power | -23.2% | -41.4% |
| 6 | ENVA | Enova International | -23.2% | 9.5% |
| 7 | ASMB | Assembly Biosciences | -22.5% | -25.1% |
| 8 | CTMX | CytomX Therapeutics | -21.9% | -35.1% |
| 9 | EIKN | Eikon Therapeutics | -20.7% | n/a |
| 10 | PWP | Perella Weinberg Partners | -20.5% | -25.4% |
Movers Over The Last Month
And over the last 21 trading days, the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | CYPH | Cypherpunk Technologies | 246.0% | 110.3% |
| 2 | INDP | Indaptus Therapeutics | 221.0% | 10.3% |
| 3 | MRNA | Moderna | 125.9% | 393.8% |
| 4 | ARCT | Arcturus Therapeutics | 91.6% | 154.5% |
| 5 | PURR | Hyperliquid Strategies | 60.0% | 221.3% |
| 6 | AMLX | Amylyx Pharmaceuticals | 52.3% | 170.1% |
| 7 | EBS | Emergent BioSolutions | 50.0% | -45.4% |
| 8 | IRD | Opus Genetics | 48.2% | 169.2% |
| 9 | CVI | CVR Energy | 45.7% | 109.8% |
| 10 | FWDI | Forward Industries | 40.4% | -9.1% |
Losers
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | ALMS | Alumis | -68.9% | -18.6% |
| 2 | RARE | Ultragenyx Pharmaceutical | -50.7% | -44.0% |
| 3 | SWMR | Swarmer | -46.7% | n/a |
| 4 | CRDO | Credo Technology | -42.9% | 12.2% |
| 5 | AEHR | Aehr Test Systems | -42.1% | 317.3% |
| 6 | ALOY | REalloys | -41.2% | n/a |
| 7 | KRMN | Karman | -40.2% | -49.5% |
| 8 | AEVA | Aeva Technologies | -39.4% | 8.4% |
| 9 | AAOI | Applied Optoelectronics | -37.5% | 177.5% |
| 10 | IMUX | Immunic | -36.9% | 89.6% |
A large price move is a starting point, not a conclusion.
The tables above highlight stocks drawing significant market attention. A large percentage gain or loss is information, not an instruction. It signals a change that merits investigation, not imitation. For example, the day’s top gainer, Beta Bionics (BBNX), returned +15.3%. A disciplined follow-up would be to examine the business itself, which saw revenue grow 52.5% over the last twelve months. The move gets your attention; the business fundamentals determine if it deserves to keep it.
The next step is never to trade the list; it is to test it. Our Guidance Momentum screen shows which risers have management raising guidance behind them, and our Buy the Dip screen shows which of the fallers still generate the growth and cash that make a recovery plausible.
Volatility Is The Cost Of Owning Stocks. Concentration Makes It A Bill
Every name on these lists made a move big enough to notice. A diversified holder reads that as noise; a concentrated holder feels it as real money. The difference is not the stock, it is the portfolio around it.
Building that portfolio is what the Trefis High Quality (HQ) Portfolio does: roughly 30 businesses with the cash generation and balance-sheet strength to absorb bad days, selected and rebalanced by rules. It has a track record of outpacing a benchmark that combines the S&P 500, the S&P MidCap 400, and the Russell 2000. Let the movers list remind you why diversification exists.