PTC Therapeutics or Eli Lilly: Which Stock Has More Upside?

LLY: Eli Lilly logo
LLY
Eli Lilly

Eli Lilly fell -5.9% during the past Day. You may be tempted to buy more, or may want to reduce your exposure. But there is an entirely different perspective you might be missing. Is there a better alternative? Turns out, its peer PTC Therapeutics gives you more. PTC Therapeutics (PTCT) stock offers superior revenue growth across key periods, better profitability, and relatively lower valuation vs Eli Lilly (LLY) stock, suggesting you may be better off investing in PTCT

  • PTCT’s Last 12 Months revenue growth was 114.5%, vs. LLY’s 44.7%.
  • In addition, its Last 3-Year Average revenue growth came in at 44.9%, ahead of LLY’s 32.1%.
  • PTCT’s LTM margin is higher: 49.5% vs. LLY’s 45.6%.

These differences become even clearer when you look at the financials side by side. The table highlights how LLY’s fundamentals stack up against those of PTCT on growth, margins, momentum, and valuation multiples.

Trefis: LLY Stock Insights

Valuation & Performance Overview

  LLY PTCT Preferred
     
Valuation      
P/EBIT Ratio 28.1 6.5 PTCT
     
Revenue Growth      
Last Quarter 42.6% -22.7% LLY
Last 12 Months 44.7% 114.5% PTCT
Last 3 Year Average 32.1% 44.9% PTCT
     
Operating Margins      
Last 12 Months 45.6% 49.5% PTCT
Last 3 Year Average 37.9% -2.0% LLY
     
Momentum      
Last 3 Year Return 189.0% 42.6% LLY

Note: For “Last 3 Year Return” metric, preferred stock is one with higher returns unless the returns are too high (>300%) which creates risk of sell off.
See more revenue details: LLY Revenue Comparison | PTCT Revenue Comparison
See more margin details: LLY Operating Income Comparison | PTCT Operating Income Comparison

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See detailed fundamentals on Buy or Sell PTCT Stock and Buy or Sell LLY Stock. Below we compare market return and related metrics across years.

Historical Market Performance

  2021 2022 2023 2024 2025 2026 Total [1] Avg Best
Returns
LLY Return 66% 34% 61% 33% 40% -8% 518%   <===
PTCT Return -35% -4% -28% 64% 68% -12% 9%    
S&P 500 Return 27% -19% 24% 23% 16% -2% 78%    
Monthly Win Rates [3]
LLY Win Rate 58% 75% 58% 58% 58% 33%   57%  
PTCT Win Rate 33% 58% 42% 83% 58% 0%   46%  
S&P 500 Win Rate 75% 42% 67% 75% 67% 33%   60% <===
Max Drawdowns [4]
LLY Max Drawdown -3% -15% -15% 0% -19% -9%   -10%  
PTCT Max Drawdown -42% -36% -53% -12% -20% -17%   -30%  
S&P 500 Max Drawdown -1% -25% -1% -2% -15% -3%   -8% <===

[1] Cumulative total returns since the beginning of 2021
[2] 2026 data is for the year up to 3/17/2026 (YTD)
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year

No matter how good the numbers, stock investment is never a smooth ride. There is a risk you must factor in. Read PTCT Dip Buyer Analyses to see how the stock has fallen and recovered in the past.

Still not sure about LLY or PTCT? Consider portfolio approach.

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