ILMN’s 11% Decline in a Week Brings Valuations Into Focus – Is IQV a Better Deal?

ILMN: Illumina logo
ILMN
Illumina

IQVIA (IQV) offers superior revenue growth across key periods, better profitability, and relatively lower valuation vs Illumina (ILMN), suggesting you may be better off investing in IQV

  • IQV’s quarterly revenue growth was 5.3%, vs. ILMN’s -4.8%.
  • In addition, its Last 12 Months revenue growth came in at 3.6%, ahead of ILMN’s -3.3%.
  • IQV’s 3-year average margin is stronger: 13.7% vs. ILMN’s 6.7%.

ILMN provides sequencing and array-based genomic analysis solutions, supporting research and clinical markets worldwide through direct sales in North America, Europe, Latin America, and Asia-Pacific. IQV provides advanced analytics, technology, and clinical research services, including cloud applications, project management, clinical trial support, virtual trials, and strategic planning for the life sciences industry globally.

Valuation & Performance Overview

  ILMN IQV Preferred
     
Valuation      
P/EBIT Ratio 17.6 13.4 IQV
     
Revenue Growth      
Last Quarter -4.8% 5.3% IQV
Last 12 Months -3.3% 3.6% IQV
Last 3 Year Average -3.0% 3.6% IQV
     
Operating Margins      
Last 12 Months 19.2% 14.4% ILMN
Last 3 Year Average 6.7% 13.7% IQV
     
Momentum      
Last 3 Year Return -50.2% -6.7% IQV

Note: For “Last 3 Year Return” metric, preferred stock is one with higher returns unless the returns are too high (>300%) which creates risk of sell off.
See more revenue details: ILMN Revenue Comparison | IQV Revenue Comparison
See more margin details: ILMN Operating Income Comparison | IQV Operating Income Comparison
 
But do these numbers tell the full story? Read Buy or Sell IQV Stock to see if IQVIA’s edge holds up under the hood or if Illumina still has cards to play (see Buy or Sell ILMN Stock).

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Historical Market Performance

  2020 2021 2022 2023 2024 2025 Total [1] Avg Best
Returns
ILMN Return 12% 3% -47% -31% -1% -31% -68%  
IQV Return 16% 57% -27% 13% -15% -10% 21%  
S&P 500 Return 16% 27% -19% 24% 23% 12% 106% <===
Monthly Win Rates [3]
ILMN Win Rate 58% 67% 25% 33% 50% 38%   45%  
IQV Win Rate 58% 75% 42% 42% 33% 50%   50%  
S&P 500 Win Rate 58% 75% 42% 67% 75% 62%   63% <===
Max Drawdowns [4]
ILMN Max Drawdown -37% -6% -53% -54% -27% -47%   -38%  
IQV Max Drawdown -46% -3% -39% -14% -17% -30%   -25%  
S&P 500 Max Drawdown -31% -1% -25% -1% -2% -15%   -12% <===

[1] Cumulative total returns since the beginning of 2020
[2] 2025 data is for the year up to 9/25/2025 (YTD)
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year

 
No matter how good the numbers, stock investment is never a smooth ride. There is a risk you must factor in. Read IQV Dip Buyer Analyses and ILMN Dip Buyer Analyses to see how these stocks have fallen and recovered in the past.