DYN Stock Down -31% after 8-Day Loss Streak
Dyne Therapeutics (DYN) stock hit day 8 of a continuous streak of days with losses, with cumulative losses over this period amounting to a -30% return. The company has lost about $358 Mil in valuation over the last 8 days, with its current market capitalization being $1.2 Bil. The stock remains 56.9% below its value at the end of 2024. This compares with year-to-date returns of 2.4% for the S&P 500 and -0.8% for the Trefis High Quality Portfolio.

Comparing DYN Stock Returns With The S&P 500
The following table summarizes the return for DYN stock vs. the S&P 500 index over different periods, including the current streak:
| Return Period | DYN | S&P 500 |
| 1D | -1.6% | 1.0% |
| 8D (Current Streak) | -31.3% | -0.2% |
| 1M (21D) | -13.6% | 3.1% |
| 3M (63D) | -15.9% | 6.3% |
| YTD 2025 | -56.9% | 2.4% |
| 2024 | 77.1% | 23.3% |
| 2023 | 14.8% | 24.2% |
| 2022 | -2.5% | -19.4% |
Gains and Losses Streaks: S&P 500 Constituents
There are currently 121 S&P constituents with 3 days or more of consecutive gains and 23 constituents with 3 days or more of consecutive losses.
| Consecutive Days | # of Gainers | # of Losers |
| 3D | 106 | 3 |
| 4D | 6 | 19 |
| 5D | 9 | 1 |
| 6D | 0 | 0 |
| 7D or more | 0 | 0 |
| Total >=3 D | 121 | 23 |
Key Financials for Dyne Therapeutics (DYN)
Last 2 Fiscal Years:
| Metric | FY2023 | FY2024 |
| Revenues | – | – |
| Operating Income | $-242.2 Mil | $-343.9 Mil |
| Net Income | $-235.9 Mil | $-317.4 Mil |
Last 2 Fiscal Quarters:
| Metric | 2024 FQ4 | 2025 FQ1 |
| Revenues | – | – |
| Operating Income | $-97.1 Mil | $-122.4 Mil |
| Net Income | $-89.5 Mil | $-115.4 Mil |
The losing streak DYN stock is currently on doesn’t inspire much confidence among investors. In contrast, Trefis High Quality (HQ) Portfolio, with a collection of 30 stocks, has a track record of comfortably outperforming the S&P 500 over the last 4-year period. Why is that? As a group, HQ Portfolio stocks provided better returns with less risk versus the benchmark index; less of a roller-coaster ride, as evident in HQ Portfolio performance metrics.