Tearsheet

Investment Highlights Why It Matters Which of these 2 stories sounds closer for this stock?

1. Generates cash flow

The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.

2. Riding a trend

Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow


0 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Advanced Diagnostics, Show more.
 
0 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Advanced Diagnostics, Show more.

Valuation, Metrics & Events

ZTS Stock


Why The Stock Moved


Qualitative Assessment

AI Generated Analysis | Feedback

Here are five key points explaining the approximate -21.4% movement of Zoetis (ZTS) stock from August 31, 2025, to December 4, 2025:

1. Zoetis reported mixed third-quarter 2025 earnings, with a revenue miss and lowered full-year guidance. Despite beating adjusted earnings per share (EPS) estimates with $1.70 against a forecast of $1.62, the company's reported revenue of $2.4 billion slightly missed the anticipated $2.41 billion. More significantly, Zoetis lowered its fiscal 2025 sales guidance from an earlier projection of $9.45 billion-$9.60 billion to a new range of $9.4 billion-$9.475 billion. This updated guidance, reflecting moderated growth expectations, contributed to a pre-market stock decline of 14.79% following the November 4, 2025, earnings release.

2. The company experienced softening demand for certain animal medicines and vaccines. Zoetis attributed its reduced sales outlook to a general moderation in growth and specifically noted softer demand for its medicines and vaccines targeting livestock, particularly pigs and chickens.

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Stock Movement Drivers

Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
ZTS Return26%48%-40%36%-17%-23%-1%
Peers Return17%8%-19%12%9%66%107%
S&P 500 Return16%27%-19%24%23%16%112%

Monthly Win Rates [3]
ZTS Win Rate67%83%33%67%50%30% 
Peers Win Rate58%54%44%50%48%57% 
S&P 500 Win Rate58%75%42%67%75%70% 

Max Drawdowns [4]
ZTS Max Drawdown-30%-13%-46%-1%-26%-28% 
Peers Max Drawdown-33%-7%-38%-18%-17%-23% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: MRK, IDXX, ELAN, PAHC, LHI. See ZTS Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 12/3/2025 (YTD)

How Low Can It Go

Unique KeyEventZTSS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-46.9%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven88.4%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-36.1%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven56.4%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven119 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-16.8%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven20.2%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven53 days120 days

Compare to MRK, IDXX, ELAN, PAHC, LHI


In The Past

Zoetis's stock fell -46.9% during the 2022 Inflation Shock from a high on 12/29/2021. A -46.9% loss requires a 88.4% gain to breakeven.

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Asset Allocation

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About Zoetis (ZTS)

Latest Trefis Analyses

Trade Ideas

Select past ideas related to ZTS. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
4.1%4.1%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-9.8%-9.8%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
6.0%6.0%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
9.7%9.7%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
6.2%6.2%-5.1%
ZTS_11072025_Dip_Buyer_ValueBuy11072025ZTSZoetisDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
3.5%3.5%-3.6%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
4.1%4.1%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-9.8%-9.8%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
6.0%6.0%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
9.7%9.7%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
6.2%6.2%-5.1%
ZTS_11072025_Dip_Buyer_ValueBuy11072025ZTSZoetisDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
3.5%3.5%-3.6%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for Zoetis

Peers to compare with:

Financials

ZTSMRKIDXXELANPAHCLHIMedian
NameZoetis Merck IDEXX La.Elanco A.Phibro A.Living H. 
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Growth & Margins

ZTSMRKIDXXELANPAHCLHIMedian
NameZoetis Merck IDEXX La.Elanco A.Phibro A.Living H. 
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Valuation

ZTSMRKIDXXELANPAHCLHIMedian
NameZoetis Merck IDEXX La.Elanco A.Phibro A.Living H. 
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Returns

ZTSMRKIDXXELANPAHCLHIMedian
NameZoetis Merck IDEXX La.Elanco A.Phibro A.Living H. 
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Financials

Segment Financials

Revenue by Segment

$ Mil20242023202220212020
Parasiticides1,9471,8601,6351,173966
Vaccines1,7711,7181,6731,4761,483
Dermatology1,4271,3291,180941770
Anti-infectives1,0571,0811,2151,2061,254
Other pharmaceuticals6781,043966821780
Pain and sedation602    
Animal health diagnostics376353374305268
Medicated feed additives354360420460470
Other non-pharmaceuticals254250231210184
Contract manufacturing & human health7886828385
Total8,5448,0807,7766,6756,260


Price Behavior

Short Interest

Short Interest: As Of Date11142025
Short Interest: Shares Quantity8,251,796
Short Interest: % Change Since 10312025-25.5%
Average Daily Volume5,953,921
Days-to-Cover Short Interest1.39
Basic Shares Quantity442,900,000
Short % of Basic Shares1.9%

SEC Filings

Expand for More

Report DateFiling DateFiling
93020251104202510-Q 9/30/2025
6302025805202510-Q 6/30/2025
3312025506202510-Q 3/31/2025
12312024213202510-K 12/31/2024
93020241104202410-Q 9/30/2024
6302024806202410-Q 6/30/2024
3312024502202410-Q 3/31/2024
12312023213202410-K 12/31/2023
93020231102202310-Q 9/30/2023
6302023808202310-Q 6/30/2023
3312023504202310-Q 3/31/2023
12312022214202310-K 12/31/2022
93020221103202210-Q 9/30/2022
6302022804202210-Q 6/30/2022
3312022505202210-Q 3/31/2022
12312021215202210-K 12/31/2021