Tearsheet

Investment Highlights Why It Matters Which of these 2 stories sounds closer for this stock?

1. Generates cash flow

The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.

2. Riding a trend

Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow


0 Attractive yield
Total YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 5.4%
Weak multi-year price returns
2Y Excs Rtn is -79%, 3Y Excs Rtn is -86%
Key risks
ZTS key risks include [1] intensifying competition threatening market share in its key companion animal franchises and [2] regulatory scrutiny and reputational challenges for specific products like Librela.
1 Attractive operating margins
Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 38%
  
2 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 31%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 24%, CFO LTM is 2.9 Bil, FCF LTM is 2.2 Bil
  
3 Low stock price volatility
Vol 12M is 29%
  
4 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Advanced Diagnostics, Show more.
  
0 Attractive yield
Total YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 5.4%
1 Attractive operating margins
Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 38%
2 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 31%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 24%, CFO LTM is 2.9 Bil, FCF LTM is 2.2 Bil
3 Low stock price volatility
Vol 12M is 29%
4 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Advanced Diagnostics, Show more.
5 Weak multi-year price returns
2Y Excs Rtn is -79%, 3Y Excs Rtn is -86%
6 Key risks
ZTS key risks include [1] intensifying competition threatening market share in its key companion animal franchises and [2] regulatory scrutiny and reputational challenges for specific products like Librela.

Valuation, Metrics & Events

ZTS Stock


Why The Stock Moved


Qualitative Assessment

AI Generated Analysis | Feedback



1. Zoetis revised its full-year 2025 revenue guidance downward on November 4, 2025. This lowered forecast, from a previous range of $9.450 - $9.600 billion to $9.400 - $9.475 billion, was a significant factor contributing to investor concern. The stock experienced a drop of over 13% in morning trading following this announcement.

2. The company cited slowing growth and weakening demand across certain key areas. This included a more measured view of macro and operational trends in the latter half of 2025, with particular softness in demand for medicines and vaccines for pigs and chickens. U.S. companion animal product sales were flat in the third quarter of 2025, and growth was generally moderated by strong year-over-year comparisons and macroeconomic factors like veterinary clinic visits.

Show more

Stock Movement Drivers

Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
ZTS Return26%48%-40%36%-17%-23%-2%
Peers Return17%8%-19%12%9%63%103%
S&P 500 Return16%27%-19%24%23%14%108%

Monthly Win Rates [3]
ZTS Win Rate67%83%33%67%50%25% 
Peers Win Rate58%54%44%50%48%54% 
S&P 500 Win Rate58%75%42%67%75%73% 

Max Drawdowns [4]
ZTS Max Drawdown-30%-13%-46%-1%-26%-28% 
Peers Max Drawdown-33%-7%-38%-18%-17%-23% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: ELAN, IDXX, MRK, PAHC. See ZTS Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 12/17/2025 (YTD)

How Low Can It Go

Unique KeyEventZTSS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-46.9%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven88.4%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-36.1%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven56.4%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven119 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-16.8%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven20.2%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven53 days120 days

Compare to MRK, IDXX, ELAN, PAHC, LHI


In The Past

Zoetis's stock fell -46.9% during the 2022 Inflation Shock from a high on 12/29/2021. A -46.9% loss requires a 88.4% gain to breakeven.

Preserve Wealth

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Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Zoetis (ZTS)

Better Bets than Zoetis (ZTS)

Latest Trefis Analyses

Trade Ideas

Select past ideas related to ZTS. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
16.8%16.8%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-6.4%-6.4%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
5.2%5.2%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
3.4%3.4%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
14.4%14.4%-5.1%
ZTS_11072025_Dip_Buyer_ValueBuy11072025ZTSZoetisDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
1.7%1.7%-3.7%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
16.8%16.8%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-6.4%-6.4%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
5.2%5.2%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
3.4%3.4%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
14.4%14.4%-5.1%
ZTS_11072025_Dip_Buyer_ValueBuy11072025ZTSZoetisDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
1.7%1.7%-3.7%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for Zoetis

Peers to compare with:

Financials

ZTSELANIDXXMRKPAHCMedian
NameZoetis Elanco A.IDEXX La.Merck Phibro A. 
Mkt Price122.2522.08695.6099.1840.6099.18
Mkt Cap54.111.055.7247.51.654.1
Rev LTM9,3974,5914,16764,2351,4004,591
Op Inc LTM3,5362411,30622,3911441,306
FCF LTM2,24035494013,04934940
FCF 3Y Avg2,01322380413,68526804
CFO LTM2,9166291,08817,065771,088
CFO 3Y Avg2,68642694517,50667945

Growth & Margins

ZTSELANIDXXMRKPAHCMedian
NameZoetis Elanco A.IDEXX La.Merck Phibro A. 
Rev Chg LTM2.7%3.1%8.4%1.7%33.7%3.1%
Rev Chg 3Y Avg5.5%0.4%7.7%2.9%14.2%5.5%
Rev Chg Q0.5%10.4%13.3%3.7%39.7%10.4%
QoQ Delta Rev Chg LTM0.1%2.4%3.2%1.0%8.0%2.4%
Op Mgn LTM37.6%5.2%31.3%34.9%10.3%31.3%
Op Mgn 3Y Avg36.8%6.2%30.1%23.7%7.7%23.7%
QoQ Delta Op Mgn LTM0.1%0.6%0.3%3.7%1.8%0.6%
CFO/Rev LTM31.0%13.7%26.1%26.6%5.5%26.1%
CFO/Rev 3Y Avg29.8%9.4%24.4%28.2%5.9%24.4%
FCF/Rev LTM23.8%7.7%22.6%20.3%2.4%20.3%
FCF/Rev 3Y Avg22.3%4.9%20.7%22.0%2.3%20.7%

Valuation

ZTSELANIDXXMRKPAHCMedian
NameZoetis Elanco A.IDEXX La.Merck Phibro A. 
Mkt Cap54.111.055.7247.51.654.1
P/S6.92.212.33.31.23.3
P/EBIT18.358.939.09.112.318.3
P/E24.4277.949.811.024.224.4
P/CFO22.215.947.012.321.421.4
Total Yield5.4%0.4%2.0%13.0%5.3%5.3%
Dividend Yield1.3%0.0%0.0%3.9%1.2%1.2%
FCF Yield 3Y Avg2.6%2.5%1.9%5.5%2.4%2.5%
D/E0.10.40.00.20.50.2
Net D/E0.10.40.00.10.40.1

Returns

ZTSELANIDXXMRKPAHCMedian
NameZoetis Elanco A.IDEXX La.Merck Phibro A. 
1M Rtn2.9%3.1%4.0%7.7%-9.7%3.1%
3M Rtn-16.5%19.8%8.5%23.3%5.5%8.5%
6M Rtn-20.6%65.6%33.8%27.4%70.5%33.8%
12M Rtn-27.5%79.4%62.9%2.8%84.7%62.9%
3Y Rtn-12.6%83.7%70.6%-0.5%253.4%70.6%
1M Excs Rtn2.2%2.3%3.2%7.0%-10.4%2.3%
3M Excs Rtn-18.0%14.3%4.8%21.3%-0.9%4.8%
6M Excs Rtn-33.0%53.3%21.4%15.0%58.1%21.4%
12M Excs Rtn-41.6%71.4%49.9%-9.4%70.9%49.9%
3Y Excs Rtn-85.8%6.3%-4.0%-68.0%174.5%-4.0%

Financials

Segment Financials

Revenue by Segment

$ Mil20242023202220212020
Parasiticides1,9471,8601,6351,173966
Vaccines1,7711,7181,6731,4761,483
Dermatology1,4271,3291,180941770
Anti-infectives1,0571,0811,2151,2061,254
Other pharmaceuticals6781,043966821780
Pain and sedation602    
Animal health diagnostics376353374305268
Medicated feed additives354360420460470
Other non-pharmaceuticals254250231210184
Contract manufacturing & human health7886828385
Total8,5448,0807,7766,6756,260


Price Behavior

Short Interest

Short Interest: As Of Date11282025
Short Interest: Shares Quantity9,178,700
Short Interest: % Change Since 1115202511.2%
Average Daily Volume5,155,379
Days-to-Cover Short Interest1.78
Basic Shares Quantity442,900,000
Short % of Basic Shares2.1%

Earnings Returns History

Expand for More

 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
11/4/2025-13.8%-17.0%-16.6%
8/5/2025-3.7%-1.8%0.4%
5/6/2025-5.2%2.4%6.7%
2/13/2025-5.1%-9.5%-7.3%
11/4/2024-3.7%-2.8%-2.8%
8/6/20246.0%5.1%7.2%
5/2/20245.5%4.1%7.0%
2/13/2024-6.7%-5.2%-10.4%
...
SUMMARY STATS   
# Positive101013
# Negative141411
Median Positive4.0%4.1%5.8%
Median Negative-3.7%-4.5%-7.3%
Max Positive6.3%12.8%18.3%
Max Negative-13.8%-17.0%-16.6%

SEC Filings

Expand for More

Report DateFiling DateFiling
93020251104202510-Q 9/30/2025
6302025805202510-Q 6/30/2025
3312025506202510-Q 3/31/2025
12312024213202510-K 12/31/2024
93020241104202410-Q 9/30/2024
6302024806202410-Q 6/30/2024
3312024502202410-Q 3/31/2024
12312023213202410-K 12/31/2023
93020231102202310-Q 9/30/2023
6302023808202310-Q 6/30/2023
3312023504202310-Q 3/31/2023
12312022214202310-K 12/31/2022
93020221103202210-Q 9/30/2022
6302022804202210-Q 6/30/2022
3312022505202210-Q 3/31/2022
12312021215202210-K 12/31/2021