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TriSalus Life Sciences (TLSI)


Market Price (5/25/2026): $3.25 | Market Cap: $167.5 Mil
Sector: Health Care | Industry: Life Sciences Tools & Services

TriSalus Life Sciences (TLSI)


Market Price (5/25/2026): $3.25
Market Cap: $167.5 Mil
Sector: Health Care
Industry: Life Sciences Tools & Services

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

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Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -13%

Strong revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is 40%

Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -48%

Megatrend and thematic drivers
Megatrends include Aging Population & Chronic Disease, and Precision Medicine. Themes include Oncology Treatments, and Targeted Therapies.

Weak multi-year price returns
2Y Excs Rtn is -108%, 3Y Excs Rtn is -148%

Meaningful short interest
Short Interest Days-to-CoverDTC = (Short Interest Share Quantity) / (Average Daily Trading Volume). Reflects how many days it would take to cover (close out) the short interest based on average volumes. High DTC can signify an increased risk of a short squeeze. is 12.25

Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -28 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -62%

Weak revenue growth
Rev Chg QQuarterly Revenue Change % is -2.9%

Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 22%

Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -45%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -45%

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -20%

Key risks
TLSI key risks include [1] substantial doubt about its ability to continue as a going concern due to significant losses and insufficient cash, Show more.

0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -13%
1 Strong revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is 40%
2 Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -48%
3 Megatrend and thematic drivers
Megatrends include Aging Population & Chronic Disease, and Precision Medicine. Themes include Oncology Treatments, and Targeted Therapies.
4 Weak multi-year price returns
2Y Excs Rtn is -108%, 3Y Excs Rtn is -148%
5 Meaningful short interest
Short Interest Days-to-CoverDTC = (Short Interest Share Quantity) / (Average Daily Trading Volume). Reflects how many days it would take to cover (close out) the short interest based on average volumes. High DTC can signify an increased risk of a short squeeze. is 12.25
6 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -28 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -62%
7 Weak revenue growth
Rev Chg QQuarterly Revenue Change % is -2.9%
8 Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 22%
9 Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -45%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -45%
10 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -20%
11 Key risks
TLSI key risks include [1] substantial doubt about its ability to continue as a going concern due to significant losses and insufficient cash, Show more.

Valuation, Metrics & Events

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

TriSalus Life Sciences (TLSI) stock has lost about 35% since 1/31/2026 because of the following key factors:

1. TriSalus Life Sciences reported Q1 2026 revenue of $8.9 million, missing analysts' expectations and leading to a downward revision of full-year 2026 revenue guidance.

The company's first-quarter 2026 revenue of $8.9 million was a decrease of 2.9% compared to the prior-year period and fell short of analyst estimates, which ranged from $10.44 million to $10.649 million. Following this, TriSalus revised its full-year 2026 revenue guidance to a range of $54 million to $57 million. This revised outlook is lower than the preliminary 2026 revenue guidance of approximately $60 million to $62 million announced in January 2026.

2. The delay in FDA clearance for TriNav Advance has impacted revenue expectations.

The FDA review process for TriNav Advance is running approximately five months behind its anticipated timeline. This delay directly contributed to the company's decision to lower its full-year 2026 revenue guidance, as the new device's market entry and sales are consequently postponed.

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Stock Movement Drivers

Fundamental Drivers

The -34.4% change in TLSI stock from 1/31/2026 to 5/24/2026 was primarily driven by a -29.7% change in the company's P/S Multiple.
(LTM values as of)13120265242026Change
Stock Price ($)4.973.26-34.4%
Change Contribution By: 
Total Revenues ($ Mil)404511.6%
P/S Multiple5.33.7-29.7%
Shares Outstanding (Mil)4352-16.5%
Cumulative Contribution-34.4%

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2026 to 5/24/2026
ReturnCorrelation
TLSI-34.4% 
Market (SPY)8.1%20.8%
Sector (XLV)-2.7%11.0%

Fundamental Drivers

The -31.2% change in TLSI stock from 10/31/2025 to 5/24/2026 was primarily driven by a -36.2% change in the company's Shares Outstanding (Mil).
(LTM values as of)103120255242026Change
Stock Price ($)4.743.26-31.2%
Change Contribution By: 
Total Revenues ($ Mil)364524.7%
P/S Multiple4.33.7-13.6%
Shares Outstanding (Mil)3352-36.2%
Cumulative Contribution-31.2%

LTM = Last Twelve Months as of date shown

Market Drivers

10/31/2025 to 5/24/2026
ReturnCorrelation
TLSI-31.2% 
Market (SPY)9.9%17.4%
Sector (XLV)4.8%15.9%

Fundamental Drivers

The -36.5% change in TLSI stock from 4/30/2025 to 5/24/2026 was primarily driven by a -46.5% change in the company's Shares Outstanding (Mil).
(LTM values as of)43020255242026Change
Stock Price ($)5.133.26-36.5%
Change Contribution By: 
Total Revenues ($ Mil)294552.5%
P/S Multiple4.83.7-22.1%
Shares Outstanding (Mil)2852-46.5%
Cumulative Contribution-36.5%

LTM = Last Twelve Months as of date shown

Market Drivers

4/30/2025 to 5/24/2026
ReturnCorrelation
TLSI-36.5% 
Market (SPY)36.0%17.1%
Sector (XLV)8.6%21.3%

Fundamental Drivers

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Market Drivers

4/30/2023 to 5/24/2026
ReturnCorrelation
TLSI-68.0% 
Market (SPY)86.3%9.5%
Sector (XLV)18.0%11.6%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
TLSI Return-6%2%-16%-41%39%-51%-67%
Peers Return16%-15%-3%10%-2%-15%-12%
S&P 500 Return27%-19%24%23%16%9%98%

Monthly Win Rates [3]
TLSI Win Rate55%67%50%50%58%40% 
Peers Win Rate51%48%48%53%53%28% 
S&P 500 Win Rate75%42%67%75%67%60% 

Max Drawdowns [4]
TLSI Max Drawdown--6%-70%-65%-38%-64% 
Peers Max Drawdown-17%-40%-41%-25%-33%-33% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: RNXT, ANGO, MMSI, BSX, BDX.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 5/22/2026 (YTD)

How Low Can It Go

EventTLSIS&P 500
2025 US Tariff Shock
  % Loss-18.5%-18.8%
  % Gain to Breakeven22.7%23.1%
  Time to Breakeven37 days79 days

Compare to RNXT, ANGO, MMSI, BSX, BDX

In The Past

TriSalus Life Sciences's stock fell -18.5% during the 2025 US Tariff Shock. Such a loss loss requires a 22.7% gain to breakeven.

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Asset Allocation

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Event

Compare to RNXT, ANGO, MMSI, BSX, BDX

In The Past

TriSalus Life Sciences's stock fell -18.5% during the 2025 US Tariff Shock. Such a loss loss requires a 22.7% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About TriSalus Life Sciences (TLSI)

TriSalus Life Sciences, Inc., an immunotherapy company that develops and commercializes immunotherapies for the treatment of liver and pancreatic tumors. The company offers the TriNav Infusion System for hepatic arterial infusion of liver tumors; and the Pancreatic Retrograde Venous Infusion System for pancreatic tumors. It also develops SD-101, an investigational immunotherapeutic with pressure-enabled drug delivery technology for hepatocellular carcinoma, intrahepatic cholangiocarcinoma, uveal melanoma with liver metastases, pancreatic ductal adenocarcinoma with liver metastases, colorectal cancer with liver metastases, and primary pancreatic cancers. The company is based in Westminster, Colorado.

AI Analysis | Feedback

Here are 1-3 brief analogies to describe TriSalus Life Sciences (TLSI):

  • The Intuitive Surgical of targeted cancer drug delivery.

  • A specialized Medtronic focused on immunotherapy drugs and their unique delivery systems for liver and pancreatic cancers.

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  • TriNav Infusion System: A device for hepatic arterial infusion of liver tumors.
  • Pancreatic Retrograde Venous Infusion System: A device designed for treating pancreatic tumors.
  • SD-101: An investigational immunotherapeutic utilizing pressure-enabled drug delivery technology for various liver and pancreatic cancers.

AI Analysis | Feedback

TriSalus Life Sciences (TLSI) sells its medical devices and develops immunotherapies primarily to other companies and institutions within the healthcare sector, rather than directly to individuals. While specific individual major customer names are not publicly disclosed by the company, as its customer base consists of numerous healthcare institutions (over 130 unique institutions as of December 2023 according to its SEC filings), its major customers fall into the following categories:

  • Hospitals: These institutions, particularly those with interventional oncology, radiology, and surgical departments specializing in liver and pancreatic care, purchase systems like the TriNav Infusion System for patient treatment.
  • Cancer Treatment Centers: Specialized facilities and clinics dedicated to comprehensive oncology care are key customers for technologies aimed at treating liver and pancreatic tumors.
  • Healthcare Systems: Larger integrated healthcare organizations that encompass multiple hospitals and clinics often make procurement decisions for their member institutions, acting as significant customers.

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Mary Szela, Chief Executive Officer and President

Mary Szela has served as CEO and President of TriSalus Life Sciences since January 2018. She brings nearly 35 years of experience in the commercial and clinical pharmaceutical arenas. Prior to TriSalus, Ms. Szela was Chief Executive Officer of Novelion Therapeutics, a rare disease company, where she orchestrated the successful merger and expansion of Aegerion Pharmaceuticals and QLT Therapeutics. She also served as Chief Executive Officer of Melinta Therapeutics, leading its revitalization efforts and accelerating clinical development of its lead asset. Earlier in her career, Ms. Szela held various leadership roles at Abbott Laboratories, including President of the company's $8 billion U.S. pharmaceutical business, and was instrumental in developing global brands such as Humira®. She currently serves on the Board of Directors for Kura Oncology, Prometheus Biosciences, Omega Therapeutics, and Senda Biosciences.

James Young, Chief Financial Officer

James Young was appointed Chief Financial Officer of TriSalus Life Sciences effective January 6, 2025. Before this role, he served as the company's Senior Vice President of Investor Relations and Treasurer. His appointment as CFO followed an 18-month period of planning and collaboration with his predecessor to ensure a seamless transition of responsibilities.

Sean Murphy, Chief Manufacturing, Strategy and Business Development Officer

Sean Murphy was appointed Chief Manufacturing, Strategy, and Business Development Officer effective January 6, 2025, transitioning from his previous role as CFO of TriSalus, which he held since June 2022. He has been a director of TriSalus since August 2020. With over 40 years of experience in healthcare operations and business development across pharmaceuticals, medical devices, and diagnostics, Mr. Murphy has a rich background. He previously served as Executive Vice President at Malin PLC, a publicly listed company investing in life sciences firms. Additionally, he was a founding member of the Evercore HealthCare practice, a prominent investment banking advisory firm. His career also includes numerous senior executive roles at Abbott Laboratories, including Head of Corporate M&A and Business Development over a 30-year tenure. He currently serves on the boards of Immucor, Xenex, and Prenosis, and previously served on the public company boards of Radius Health and Poseida.

Dr. Richard Marshak, Chief Commercial Officer

Dr. Richard Marshak was appointed Chief Commercial Officer of TriSalus Life Sciences effective January 6, 2025. He previously served as Senior Vice President of Corporate Development, Strategy, and Marketing at TriSalus since June 2022. Dr. Marshak brings extensive experience from leadership positions, including serving as Chief Executive Officer of Mount Tam Biotechnologies and co-founder of Nephraegis Therapeutics. He also held ascending leadership roles at Abbott Laboratories, culminating as Head of Global Strategic Pricing, which included their flagship product, Humira.

Jodi Devlin, Chief of Clinical Strategy and Operations

Jodi Devlin was appointed Chief of Clinical Strategy and Operations effective January 6, 2025. She joined TriSalus Life Sciences in August 2023 as President of Commercial Operations. Ms. Devlin has a strong background in the biotech, medical device, and pharmaceutical industries.

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Key Risks to TriSalus Life Sciences (TLSI)

TriSalus Life Sciences, Inc. (TLSI) faces several key risks inherent in the biotechnology and medical technology sectors, particularly given its focus on novel drug delivery systems and investigational immunotherapies for difficult-to-treat cancers. These risks primarily revolve around the complex processes of clinical development and regulatory approval, ongoing financial sustainability, and the successful commercialization and market adoption of its products.

1. Clinical Development and Regulatory Approval Challenges: A significant risk for TriSalus is the inherent uncertainty and potential for delays in the clinical development and regulatory approval pathways for its product candidates. This includes the investigational immunotherapeutic, nelitolimod (SD-101), currently in clinical trials for various liver and pancreatic cancers. Delays in the release of clinical data, such as from the PERIO-03 study, or unexpected findings regarding safety or efficacy in ongoing or future trials, could significantly impact the company's ability to bring these therapies to market. Furthermore, challenges and delays in obtaining regulatory clearances for new iterations of its existing products, like the TriNav Advance, pose an additional risk. The company's focus on "hard-to-treat" tumors also implies a higher historical rate of development failures in this complex therapeutic area.

2. Financial Sustainability and Capital Requirements: TriSalus Life Sciences is currently operating in a "heavy investment mode" and has reported net losses. The company's ability to continue funding its extensive research and development efforts, clinical trials, and commercial expansion relies heavily on its capacity to raise additional capital through equity offerings. This reliance on external financing presents risks of significant shareholder dilution and uncertainty regarding the company's ability to achieve profitability within its projected timeline. Upfront investments in sales infrastructure and commercial expansion also influence near-term revenue phasing.

3. Commercialization and Market Acceptance: Even with regulatory approvals, TriSalus faces substantial risks related to the commercialization and market acceptance of its drug delivery systems, such as the TriNav Infusion System, and any future products. These risks include the ability to successfully gain market share in both existing and new indications, particularly in non-liver markets. The company must also navigate intense market competition and ensure that its products receive adequate insurance coverage and reimbursement from payers, as a lack of favorable coverage could compromise commercial success. Additionally, any performance issues with its products could harm the company's reputation and hinder market adoption.

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TriSalus Life Sciences (NASDAQ: TLSI) focuses on developing and commercializing immunotherapies and drug delivery systems for liver and pancreatic tumors. The addressable markets for their main products and services are as follows:

TriNav Infusion System for Hepatic Arterial Infusion of Liver Tumors

  • TriSalus estimates the market opportunity for its current TriNav portfolio of devices in Transarterial Chemoembolization (TACE) and Transarterial Radioembolization (TARE) procedures for liver cancers in the U.S. to be approximately $494 million annually, based on approximately 62,000 units.
  • The launch of the TriNav LV system is expected to provide full access to the U.S. $375 million liver embolization market.
  • More broadly, TriSalus estimates a U.S. total addressable Pressure-Enabled Drug Delivery (PEDD) market, which includes liver cancers and other conditions, to exceed $2.3 billion annually.

Pancreatic Retrograde Venous Infusion System for Pancreatic Tumors

  • TriSalus believes its pancreatic infusion technology could potentially treat two thousand patients annually, adding an additional U.S. market expansion of $400 million.
  • The global pancreatic cancer treatment market was estimated at $2.92 billion in 2024 and is projected to reach $5.84 billion by 2030. North America held a 39.27% share of this market in 2024, with the U.S. accounting for 89.00% of North America in 2023. The U.S. pancreatic cancer treatment market was valued at $1.75 billion in 2025 and is projected to reach approximately $5.46 billion by 2035.

SD-101 (Investigational Immunotherapeutic with Pressure-Enabled Drug Delivery Technology)

  • Hepatocellular Carcinoma (HCC): The global hepatocellular carcinoma (HCC) treatment market size is expected to be valued at $5.2 billion in 2026, growing to $9.4 billion by 2033. North America is projected to account for 38% of this market in 2026. The global liver cancer market, which HCC heavily influences (74.88% share in 2025), was valued at $15.05 billion in 2025 and is estimated to reach $37.78 billion by 2031.
  • Intrahepatic Cholangiocarcinoma (ICC): The global intrahepatic cholangiocarcinoma market is estimated to be valued at $1.10 billion in 2025 and is expected to reach $1.90 billion by 2032. Another estimate places the global market at $1.7 billion in 2024, growing to $2.9 billion by 2030. The U.S. market for ICC is expected to grow from approximately $0.51 billion in 2024 to about $0.83 billion by 2030.
  • Uveal Melanoma with Liver Metastases (UM-LM): The global uveal melanoma market, driven by its metastatic potential to the liver, was valued at $402.5 million in 2024 and is projected to reach approximately $609.7 million by 2030. The broader global liver metastases treatment market (which includes UM-LM) was estimated at $1.63 billion in 2023 and is projected to grow to $2.66 billion by 2030. North America dominated this market with a 40.82% share in 2023.
  • Pancreatic Ductal Adenocarcinoma with Liver Metastases & Primary Pancreatic Cancers: These fall under the broader pancreatic cancer market previously described.
  • Colorectal Cancer with Liver Metastases: The global metastatic colorectal cancer market is projected to reach $19.06 billion by 2035 from $6.78 billion in 2024. Another source estimates the global market at $10.95 billion in 2025, reaching $19.13 billion by 2032. The U.S. accounted for approximately 45% of the total metastatic colorectal cancer market size in 2024, which was more than $13 billion across the seven major markets (7MM).

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TriSalus Life Sciences (TLSI) anticipates several key drivers for future revenue growth over the next 2-3 years, focusing on expanding its proprietary Pressure-Enabled Drug Delivery (PEDD) platform and TriNav Infusion System. These drivers include:

  • Expansion into New Indications and Markets: TriSalus aims to broaden the application of its TriNav platform and PEDD technology beyond existing liver-directed therapies into new solid tumor indications. The company is actively exploring and developing applications for conditions such as uterine fibroids, symptomatic thyroid disease, and knee osteoarthritis, and continuing to target hepatocellular carcinoma, intrahepatic cholangiocarcinoma, uveal melanoma with liver metastases, pancreatic ductal adenocarcinoma with liver metastases, and colorectal cancer with liver metastases.
  • Launch of New and Enhanced TriNav Products: TriSalus is committed to continuously innovating and expanding its product portfolio. The company has already increased its commercial offerings from 2 at the start of 2025 to 7 by early 2026, with specific new launches including TriNav LV, TriGuide, TriNav FLX, and TriNav XP. The anticipated launch of TriNav Advance in the first half of 2026, pending regulatory clearance, is expected to capture new market segments and drive more procedures per account.
  • Expansion of Sales and Commercial Infrastructure: A significant driver of growth is the strategic investment in and expansion of TriSalus's sales and commercial organization. The company plans to aggressively invest in its sales force, including a stated goal of doubling its size, to deepen engagement within the interventional radiology community and drive broader adoption of the PEDD platform and TriNav product suite.
  • Continued Growth in Core Liver-Directed Therapies: The company expects continued revenue growth from increased sales of its TriNav units within its established liver-directed therapy applications. This sustained market penetration in the liver embolization market remains a fundamental component of its growth strategy.
  • Investment in Clinical Studies and Data Generation: TriSalus is prioritizing aggressive investment in foundational clinical and registry studies to further validate the value of its PEDD technology and generate differentiated clinical data across various vascular anatomies and indications. This evidence is crucial for supporting broader clinical adoption and expanding into new applications.
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Share Issuance

  • In February 2026, TriSalus Life Sciences priced an underwritten public offering of 9,756,100 shares of its common stock at $4.10 per share, expecting to raise approximately $40.0 million in gross proceeds. Net proceeds are estimated at around $37.0 million, or approximately $42.64 million if the underwriters' over-allotment option is fully exercised.
  • The company completed a private placement in April 2025, issuing 5,500,000 shares of common stock at $4.00 per share, which generated approximately $22.0 million in gross proceeds.
  • An exchange offer and consent solicitation for Series A Convertible Preferred Stock was completed in July 2025, aiming to simplify the capital structure by converting preferred shares into common stock. Approximately 98.82% of the outstanding preferred shares were tendered and accepted.

Inbound Investments

  • A public offering in February 2026 is expected to generate approximately $40.0 million in gross proceeds, or $46 million according to other sources, designated for general corporate purposes, including capital expenditures, working capital, and administrative costs, to accelerate strategic initiatives.
  • In April 2025, TriSalus secured approximately $22.0 million in gross proceeds through a private placement of common stock, with investments from Nantahala Capital, Broadfin Holdings, and other healthcare-focused institutional investors.
  • TriSalus obtained an additional $10 million from the OrbiMed debt facility to support its growth initiatives.

Capital Expenditures

  • Proceeds from the February 2026 public offering are intended to be used, in part, for capital expenditures.
  • Non-cash capital expenditures included in trade payables for the year ended December 31, 2025, amounted to $68,000.
  • There were no non-cash capital expenditures reported as included in trade payables for the year ended December 31, 2024.

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Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

TLSIRNXTANGOMMSIBSXBDXMedian
NameTriSalus.RenovoRx AngioDyn.Merit Me.Boston S.Becton D. 
Mkt Price3.260.8811.9264.1757.78147.6334.85
Mkt Cap0.20.00.53.885.841.42.2
Rev LTM4513141,54220,61521,366928
Op Inc LTM-28-13-201884,1063,09387
FCF LTM-20-1122173,2983,057109
FCF 3Y Avg-36-10-171752,5252,89582
CFO LTM-20-1142974,3413,831151
CFO 3Y Avg-35-10-122303,5433,630110

Growth & Margins

TLSIRNXTANGOMMSIBSXBDXMedian
NameTriSalus.RenovoRx AngioDyn.Merit Me.Boston S.Becton D. 
Rev Chg LTM39.6%520.4%10.7%11.1%17.4%6.4%14.3%
Rev Chg 3Y Avg53.9%--1.7%9.6%16.5%4.4%9.6%
Rev Chg Q-2.9%185.8%8.9%7.5%11.6%5.2%8.2%
QoQ Delta Rev Chg LTM-0.6%32.6%2.1%1.7%2.7%1.1%1.9%
Op Inc Chg LTM11.9%-10.9%22.0%15.5%26.6%22.3%18.8%
Op Inc Chg 3Y Avg2.5%-8.1%-4.3%20.1%24.4%8.2%5.3%
Op Mgn LTM-62.4%-864.3%-6.5%12.2%19.9%14.5%2.8%
Op Mgn 3Y Avg-138.7%--8.4%11.5%18.5%13.2%11.5%
QoQ Delta Op Mgn LTM-2.8%249.7%0.2%-0.1%0.1%0.5%0.2%
CFO/Rev LTM-44.5%-759.0%1.4%19.3%21.1%17.9%9.7%
CFO/Rev 3Y Avg-127.8%--4.1%16.2%19.9%17.8%16.2%
FCF/Rev LTM-45.4%-759.0%0.5%14.1%16.0%14.3%7.3%
FCF/Rev 3Y Avg-130.1%--5.6%12.4%14.0%14.2%12.4%

Valuation

TLSIRNXTANGOMMSIBSXBDXMedian
NameTriSalus.RenovoRx AngioDyn.Merit Me.Boston S.Becton D. 
Mkt Cap0.20.00.53.885.841.42.2
P/S3.722.51.62.54.21.93.1
P/Op Inc-6.0-2.6-24.220.420.913.45.4
P/EBIT-7.8-2.6-24.217.920.918.47.7
P/E-6.2-2.7-15.827.424.136.410.7
P/CFO-8.4-3.0111.512.819.810.811.8
Total Yield-16.3%-36.7%-6.3%3.6%4.2%5.6%-1.3%
Dividend Yield0.0%0.0%0.0%0.0%0.0%2.9%0.0%
FCF Yield 3Y Avg-18.4%-37.1%-5.7%3.7%2.3%5.0%-1.7%
D/E0.20.00.00.20.10.40.2
Net D/E-0.1-0.4-0.10.10.10.40.0

Returns

TLSIRNXTANGOMMSIBSXBDXMedian
NameTriSalus.RenovoRx AngioDyn.Merit Me.Boston S.Becton D. 
1M Rtn-29.7%2.9%7.4%-6.4%-6.9%-3.0%-4.7%
3M Rtn-40.2%-3.4%6.2%-21.9%-22.5%-19.9%-20.9%
6M Rtn-35.7%10.8%-0.3%-26.4%-40.4%-1.4%-13.9%
12M Rtn-41.4%-25.9%26.1%-32.7%-44.7%12.2%-29.3%
3Y Rtn-68.7%-53.6%27.2%-20.7%12.1%-17.9%-19.3%
1M Excs Rtn-34.7%-7.2%1.3%-11.6%-17.2%-9.8%-10.7%
3M Excs Rtn-44.0%-11.5%-3.0%-30.7%-31.6%-28.7%-29.7%
6M Excs Rtn-41.3%7.8%-12.3%-35.8%-53.0%-13.1%-24.5%
12M Excs Rtn-67.9%-55.6%-3.3%-61.4%-72.7%-16.8%-58.5%
3Y Excs Rtn-148.1%-137.7%-54.9%-103.3%-71.5%-100.7%-102.0%

Comparison Analyses

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Financials

Segment Financials

Revenue by Segment
$ Mil2025202420232022
Single Segment2919128
Total2919128


Price Behavior

Price Behavior
Market Price$3.26 
Market Cap ($ Bil)0.2 
First Trading Date02/08/2021 
Distance from 52W High-56.5% 
   50 Days200 Days
DMA Price$4.06$4.94
DMA Trenddowndown
Distance from DMA-19.8%-34.0%
 3M1YR
Volatility102.1%79.4%
Downside Capture193.79161.45
Upside Capture-52.1748.23
Correlation (SPY)21.1%17.9%
TLSI Betas & Captures as of 4/30/2026

 1M2M3M6M1Y3Y
Beta2.552.012.251.681.330.52
Up Beta2.922.912.582.521.970.58
Down Beta1.330.121.270.470.570.40
Up Capture164%151%225%176%88%9%
Bmk +ve Days15223166141428
Stock +ve Days13192858114341
Down Capture167%246%230%162%143%91%
Bmk -ve Days4183056108321
Stock -ve Days8233565134361

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with TLSI
TLSI-40.9%79.2%-0.29-
Sector ETF (XLV)16.0%14.5%0.8021.8%
Equity (SPY)29.5%12.0%1.8618.0%
Gold (GLD)35.5%26.8%1.114.5%
Commodities (DBC)42.9%18.7%1.77-4.5%
Real Estate (VNQ)15.2%13.1%0.8220.1%
Bitcoin (BTCUSD)-31.3%41.8%-0.786.3%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with TLSI
TLSI-23.4%62.1%-0.23-
Sector ETF (XLV)5.7%14.7%0.218.5%
Equity (SPY)14.0%17.0%0.647.3%
Gold (GLD)18.8%18.0%0.854.7%
Commodities (DBC)10.4%19.4%0.420.0%
Real Estate (VNQ)3.8%18.8%0.108.9%
Bitcoin (BTCUSD)11.6%55.3%0.418.8%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with TLSI
TLSI-13.3%60.4%-0.26-
Sector ETF (XLV)9.9%16.5%0.498.5%
Equity (SPY)15.7%17.9%0.757.6%
Gold (GLD)13.0%16.0%0.674.8%
Commodities (DBC)7.8%17.9%0.350.3%
Real Estate (VNQ)5.5%20.7%0.239.1%
Bitcoin (BTCUSD)66.7%66.9%1.068.9%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date4302026
Short Interest: Shares Quantity1.4 Mil
Short Interest: % Change Since 41520269.0%
Average Daily Volume0.1 Mil
Days-to-Cover Short Interest12.2 days
Basic Shares Quantity51.5 Mil
Short % of Basic Shares2.8%

Earnings Returns History

Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
3/5/2026-6.4%-14.0%-14.5%
11/13/20253.9%13.0%69.0%
8/12/20258.2%27.4%28.2%
4/30/2025-10.3%-10.1%-4.2%
1/23/20255.3%-0.2%17.8%
11/14/2024-10.9%-9.6%-13.1%
8/15/20240.6%-5.3%-22.8%
4/1/20245.1%0.5%-3.9%
...
SUMMARY STATS   
# Positive534
# Negative465
Median Positive5.1%13.0%38.3%
Median Negative-8.4%-8.3%-13.1%
Max Positive8.2%27.4%69.0%
Max Negative-10.9%-14.0%-22.8%

SEC Filings

Expand for More
Report DateFiling DateFiling
03/31/202605/12/202610-Q
12/31/202503/05/202610-K
09/30/202511/13/202510-Q
06/30/202508/12/202510-Q
03/31/202505/15/202510-Q
12/31/202404/15/202510-K
09/30/202411/14/202410-Q
06/30/202408/14/202410-Q
03/31/202405/15/202410-Q
12/31/202304/11/202410-K
09/30/202311/14/202310-Q
03/31/202307/18/2023424B3

Recent Forward Guidance [BETA]

Latest: Q1 2026 Earnings Reported 5/12/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2026 Revenue54.00 Mil55.50 Mil57.00 Mil-9.0% LoweredGuidance: 61.00 Mil for 2026

Prior: Q4 2025 Earnings Reported 3/5/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2026 Revenue60.00 Mil61.00 Mil62.00 Mil0 AffirmedGuidance: 61.00 Mil for 2026

Insider Activity

Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Wahlstrom, Mats DirectBuy51820262.5360,000151,800373,314Form
2Stansky, Michael P DirectBuy51820262.50410,0001,025,0003,101,805Form
3Stansky, Michael P Skyview Investments LLCBuy51820262.50200,000500,000999,245Form
4Szela, Mary TCEO and PresidentDirectBuy51820262.5939,682102,7762,758,907Form
5Patience, DavidChief Financial OfficerDirectBuy51820262.437,10017,253670,090Form