Tearsheet

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Megatrend and thematic drivers
Megatrends include Aging Population & Chronic Disease, and Precision Medicine. Themes include Oncology Treatments, Targeted Therapies, Show more.

Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0

Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -31 Mil

Stock price has recently run up significantly
6M Rtn6 month market price return is 223%, 12M Rtn12 month market price return is 454%

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -6.2%

Significant short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 35%

Key risks
SLS key risks include [1] a critical dependency on the success of its pivotal Phase 3 REGAL trial for drug candidate GPS and [2] overcoming intense competition in the saturated Acute Myeloid Leukemia market to achieve market adoption.

0 Megatrend and thematic drivers
Megatrends include Aging Population & Chronic Disease, and Precision Medicine. Themes include Oncology Treatments, Targeted Therapies, Show more.
1 Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
2 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -31 Mil
3 Stock price has recently run up significantly
6M Rtn6 month market price return is 223%, 12M Rtn12 month market price return is 454%
4 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -6.2%
5 Significant short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 35%
6 Key risks
SLS key risks include [1] a critical dependency on the success of its pivotal Phase 3 REGAL trial for drug candidate GPS and [2] overcoming intense competition in the saturated Acute Myeloid Leukemia market to achieve market adoption.

SLS in ETFs

Weight = SLS's share of each fund

VTI0.00%
VTI0.00%
ITOT0.00%
IWM0.04%
XBI0.47%
IWO0.08%
VTWO0.05%
VHT0.03%
+2 more covered ETFs

Valuation & Metrics

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Updated on 6/22/2026

SELLAS Life Sciences (SLS) stock has gained about 75% since 2/28/2026 because of the following key factors:

1. Significant Advancement in the Pivotal Phase 3 REGAL Trial for GPS.

SELLAS Life Sciences' stock gained momentum as its pivotal Phase 3 REGAL trial for Galinpepimut-S (GPS) in Acute Myeloid Leukemia (AML) approached its final analysis, with 78 of the 80 required events recorded as of May 11, 2026, during fiscal Q2 2026. The anticipation of these results, coupled with CEO Angelos Stergiou's comments suggesting patient survival times in the trial were "longer than expected," fueled investor optimism regarding the potential success of the immunotherapy.

2. Expansion and Promising Data for the SLS009 Clinical Program.

The company initiated an 80-patient Phase 2 trial of SLS009 (tambiciclib) in newly diagnosed, first-line AML patients on March 12, 2026, within fiscal Q1 2026, following positive Phase 2 results in relapsed/refractory AML which showed a 46% overall response rate (29% complete remission/complete remission with incomplete hematologic recovery) in 35 evaluable patients. Further boosting confidence, preclinical data for SLS009 presented at the 2026 American Association for Cancer Research (AACR) demonstrated the drug's ability to induce apoptosis in AML cell lines, including those with high-risk ASXL1 and TP53 mutations.

Show more
Updated on 6/22/2026

SELLAS Life Sciences (SLS) stock has gained about 75% since 2/28/2026 because of the following key factors:

1. Significant Advancement in the Pivotal Phase 3 REGAL Trial for GPS.

SELLAS Life Sciences' stock gained momentum as its pivotal Phase 3 REGAL trial for Galinpepimut-S (GPS) in Acute Myeloid Leukemia (AML) approached its final analysis, with 78 of the 80 required events recorded as of May 11, 2026, during fiscal Q2 2026. The anticipation of these results, coupled with CEO Angelos Stergiou's comments suggesting patient survival times in the trial were "longer than expected," fueled investor optimism regarding the potential success of the immunotherapy.

2. Expansion and Promising Data for the SLS009 Clinical Program.

The company initiated an 80-patient Phase 2 trial of SLS009 (tambiciclib) in newly diagnosed, first-line AML patients on March 12, 2026, within fiscal Q1 2026, following positive Phase 2 results in relapsed/refractory AML which showed a 46% overall response rate (29% complete remission/complete remission with incomplete hematologic recovery) in 35 evaluable patients. Further boosting confidence, preclinical data for SLS009 presented at the 2026 American Association for Cancer Research (AACR) demonstrated the drug's ability to induce apoptosis in AML cell lines, including those with high-risk ASXL1 and TP53 mutations.

3. Strengthened Cash Position to Fund Clinical Programs.

SELLAS significantly bolstered its financial runway, reporting $107.1 million in cash and cash equivalents as of March 31, 2026, at the end of fiscal Q1 2026. This was further enhanced by an additional $7.5 million in proceeds from warrant exercises received in fiscal Q2 2026. Overall, the company's cash position was reported to be over $135 million, providing substantial capital to advance its ongoing clinical development efforts.

4. Positive Analyst Sentiment and Better-than-Expected Fiscal Q1 2026 Earnings.

Investor confidence was further supported by positive analyst sentiment, including a Zacks Rank #2 (Buy) upgrade on March 26, 2026, in fiscal Q1 2026, and an average analyst price target ranging from $10.00 to $10.20. This was complemented by the company's fiscal Q1 2026 financial results, reported on May 12, 2026, in fiscal Q2 2026, where SELLAS announced a net loss per share of -$0.05, surpassing analysts' expectations of -$0.06 by 16.67%.

Show less
Holding a concentrated position? Know your true downside before the momentum shifts.
Protect Your Wealth →

Stock Movement Drivers

Fundamental Drivers

The 73.0% change in SLS stock from 2/28/2026 to 6/22/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)22820266222026Change
Stock Price ($)4.938.5373.0%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)108172-37.2%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

2/28/2026 to 6/22/2026
ReturnCorrelation
SLS73.0% 
Market (SPY)8.8%47.0%
Sector (XLV)-5.9%35.3%

Fundamental Drivers

The 426.5% change in SLS stock from 11/30/2025 to 6/22/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)113020256222026Change
Stock Price ($)1.628.53426.5%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)108172-37.2%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

11/30/2025 to 6/22/2026
ReturnCorrelation
SLS426.5% 
Market (SPY)9.5%30.4%
Sector (XLV)-4.0%18.6%

Fundamental Drivers

The 398.8% change in SLS stock from 5/31/2025 to 6/22/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)53120256222026Change
Stock Price ($)1.718.53398.8%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)88172-49.1%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

5/31/2025 to 6/22/2026
ReturnCorrelation
SLS398.8% 
Market (SPY)27.7%24.2%
Sector (XLV)15.2%16.3%

Fundamental Drivers

The 397.4% change in SLS stock from 5/31/2023 to 6/22/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)53120236222026Change
Stock Price ($)1.728.53397.4%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)24172-86.3%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

5/31/2023 to 6/22/2026
ReturnCorrelation
SLS397.4% 
Market (SPY)85.1%14.1%
Sector (XLV)23.4%15.2%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
SLS Return-5%-57%-55%-2%262%114%39%
Peers Return-30%-42%107%-56%10%8%-56%
S&P 500 Return27%-19%24%23%16%10%100%

Monthly Win Rates [3]
SLS Win Rate42%50%50%33%58%50% 
Peers Win Rate27%40%57%40%48%53% 
S&P 500 Win Rate75%42%67%75%67%50% 

Max Drawdowns [4]
SLS Max Drawdown-61%-75%-77%-52%-37%-33% 
Peers Max Drawdown-66%-68%-63%-72%-57%-37% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: KURA, TCRX, AGEN, MRKR, IMMX.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 6/22/2026 (YTD)

How Low Can It Go

EventSLSS&P 500
2025 US Tariff Shock
  % Loss-17.5%-18.8%
  % Gain to Breakeven21.2%23.1%
  Time to Breakeven11 days79 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-44.7%-9.5%
  % Gain to Breakeven80.7%10.5%
  Time to Breakeven162 days24 days
2023 SVB Regional Banking Crisis
  % Loss-63.1%-6.7%
  % Gain to Breakeven171.2%7.1%
  Time to Breakeven1007 days31 days
2022 Inflation Shock & Fed Tightening
  % Loss-69.3%-24.5%
  % Gain to Breakeven225.6%32.4%
  Time to Breakeven1245 days427 days
2020 COVID-19 Crash
  % Loss-34.6%-33.7%
  % Gain to Breakeven52.9%50.9%
  Time to Breakeven27 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-29.1%-19.2%
  % Gain to Breakeven41.1%23.8%
  Time to Breakeven3 days105 days

Compare to KURA, TCRX, AGEN, MRKR, IMMX

In The Past

SELLAS Life Sciences's stock fell -17.5% during the 2025 US Tariff Shock. Such a loss loss requires a 21.2% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventSLSS&P 500
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-44.7%-9.5%
  % Gain to Breakeven80.7%10.5%
  Time to Breakeven162 days24 days
2023 SVB Regional Banking Crisis
  % Loss-63.1%-6.7%
  % Gain to Breakeven171.2%7.1%
  Time to Breakeven1007 days31 days
2022 Inflation Shock & Fed Tightening
  % Loss-69.3%-24.5%
  % Gain to Breakeven225.6%32.4%
  Time to Breakeven1245 days427 days
2020 COVID-19 Crash
  % Loss-34.6%-33.7%
  % Gain to Breakeven52.9%50.9%
  Time to Breakeven27 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-29.1%-19.2%
  % Gain to Breakeven41.1%23.8%
  Time to Breakeven3 days105 days
2015-2016 China Devaluation / Global Growth Scare
  % Loss-57.5%-12.2%
  % Gain to Breakeven135.2%13.9%
  Time to Breakeven59 days62 days
2013 Taper Tantrum
  % Loss-40.2%-0.2%
  % Gain to Breakeven67.3%0.2%
  Time to Breakeven112 days1 days
2011 US Debt Ceiling Crisis & European Contagion
  % Loss-49.6%-17.9%
  % Gain to Breakeven98.5%21.8%
  Time to Breakeven158 days123 days
2010 Eurozone Sovereign Debt Crisis / Flash Crash
  % Loss-52.9%-15.4%
  % Gain to Breakeven112.3%18.2%
  Time to Breakeven1243 days125 days

Compare to KURA, TCRX, AGEN, MRKR, IMMX

In The Past

SELLAS Life Sciences's stock fell -17.5% during the 2025 US Tariff Shock. Such a loss loss requires a 21.2% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About SELLAS Life Sciences (SLS)

```html

SELLAS Life Sciences (SLS) is a late-stage biopharmaceutical company focused on developing novel cancer immunotherapies. The company's core mission is to create innovative treatments that harness the body's immune system to combat a variety of cancer indications, aiming to provide new therapeutic options for patients with significant unmet medical needs.

The company's lead product candidate is galinpepimut-S (GPS), an immunotherapeutic agent that targets the Wilms tumor 1 (WT1) protein, which is frequently overexpressed in various cancers. GPS is currently in Phase III clinical trials for acute myeloid leukemia (AML) and in Phase 1/2 trials for ovarian cancer. SELLAS also maintains a strategic collaboration with Merck & Co., Inc. to evaluate GPS in combination with the PD1 blocker pembrolizumab, spanning Phase 1/2 clinical trials for up to five different cancer indications, including both hematologic malignancies and solid tumors. Additionally, SELLAS is developing nelipepimut-S, an immunotherapy targeting the human epidermal growth factor receptor 2 (HER2), which is in Phase 2b clinical trials for early-stage breast cancer.

SELLAS Life Sciences primarily serves the oncology market, with its product pipeline designed to address patients battling challenging cancers such as acute myeloid leukemia, ovarian cancer, and early-stage breast cancer. Its potential customers are healthcare providers and patients within the global cancer therapy landscape, seeking advanced immunotherapy options for a broad spectrum of solid tumors and hematologic cancers.

```

AI Analysis | Feedback

Here are 1-2 brief analogies for SELLAS Life Sciences (SLS):

  • Think of them as a Moderna or BioNTech, but for novel cancer immunotherapies instead of vaccines, still aiming for their big breakthrough.
  • A focused biotech company, similar to a younger Genentech, specializing in developing new cancer immunotherapy drugs.

AI Analysis | Feedback

```html
  • galinpepimut-S (GPS): A cancer immunotherapeutic agent targeting Wilms tumor 1, in Phase III clinical trials for acute myeloid leukemia and Phase 1/2 for ovarian cancer.
  • nelipepimut-S: A cancer immunotherapy targeting human epidermal growth factor receptor 2, in Phase 2b clinical trials for early-stage breast cancer.
```

AI Analysis | Feedback

SELLAS Life Sciences (SLS) is a late-stage biopharmaceutical company primarily focused on the research and development of novel cancer immunotherapies. Its lead product candidates, galinpepimut-S (GPS) and nelipepimut-S, are currently in various phases of clinical trials (Phase III, Phase 1/2, and Phase 2b).

As their product candidates are still in development and have not yet received regulatory approval for commercial sale, SELLAS Life Sciences does not currently have major customers that purchase its therapeutic products. The company's activities are centered on advancing its pipeline through clinical trials.

While SELLAS has a strategic collaboration with Merck & Co., Inc. (NYSE: MRK) for the evaluation of GPS in combination with pembrolizumab, this relationship is a development partnership rather than a customer-vendor arrangement for product sales.

AI Analysis | Feedback

null

AI Analysis | Feedback

Dr. Angelos M. Stergiou, President and Chief Executive Officer

Dr. Stergiou is the founder of SELLAS Life Sciences Group, Inc.. Prior to founding SELLAS in 2012, he co-founded Genesis Life Sciences, Ltd. (now Genesis Research), where he served as President and Chief Operating Officer from 2009 to 2011. From 2002 to 2009, he held international positions of increasing responsibility in pharmaceutical and biotechnology companies, including PAION AG, Accentia Biopharmaceuticals, BioVest International, Analytica International, and Anavex Life Sciences. Dr. Stergiou led the Phase 3 development of a therapeutic cancer vaccine, BiovaxID, and holds a patent on the technology.

John T. Burns, Vice President Finance, Corporate Controller and Interim Principal Accounting Officer

John T. Burns serves as the Vice President Finance, Corporate Controller, and Interim Principal Accounting Officer at SELLAS Life Sciences.

Dragan Cicic, Senior Vice President, Clinical Development

Dr. Cicic has 20 years of experience in the biopharmaceutical industry. Before joining SELLAS, he was a Senior Vice President, Clinical Lead, at Klus Pharma, where he led the global clinical development of targeted solid cancer biologicals. He also held senior management positions at Actinium Pharmaceuticals, launching key clinical trials in hematologic malignancies. Dr. Cicic received his medical degree from the University of Belgrade and an MBA from the Wharton School of the University of Pennsylvania.

Stacy Yeung, Vice President, Associate General Counsel, and Head of Compliance

Stacy Yeung has 20 years of relevant experience and was promoted to Vice President, Associate General Counsel, and Head of Compliance as of March 8, 2024, leading the Company's legal and compliance functions.

AI Analysis | Feedback

```html

Here are the key risks to SELLAS Life Sciences (SLS):

  1. Clinical Trial and Regulatory Approval Risk: As a late-stage biopharmaceutical company, SELLAS Life Sciences' success is heavily dependent on the successful outcome of its ongoing clinical trials and the subsequent receipt of regulatory approvals for its product candidates. The lead candidate, galinpepimut-S (GPS), is in Phase III for acute myeloid leukemia and Phase 1/2 for ovarian cancer, while nelipepimut-S is in Phase 2b for early-stage breast cancer. There is no guarantee that these clinical trials will demonstrate sufficient efficacy and safety, or that regulatory bodies will grant approval, which could significantly jeopardize the company's future prospects.
  2. Pipeline Concentration Risk: The company's future value and viability are substantially tied to the successful development and commercialization of a limited number of product candidates, primarily galinpepimut-S (GPS) and nelipepimut-S. A failure in the development, clinical trials, or regulatory approval process of one or both of these key candidates would have a disproportionately severe negative impact on SELLAS Life Sciences, given the lack of a broad and diversified product pipeline.
```

AI Analysis | Feedback

null

AI Analysis | Feedback

For SELLAS Life Sciences (symbol: SLS), the addressable markets for their main products are as follows:

  • Galinpepimut-S (GPS) for Acute Myeloid Leukemia (AML): The global acute myeloid leukemia treatment market was valued at approximately USD 3.91 billion in 2025. It is projected to grow to USD 9.79 billion by 2034. North America represented approximately 41% of this global market in 2025.
  • Galinpepimut-S (GPS) for Ovarian Cancer: The global ovarian cancer treatment market (specifically for High-Grade vs. Low-Grade Serous Ovarian Cancer) was valued at USD 3.012 billion in 2025 and is expected to grow to USD 5.703 billion by 2034. The United States accounted for nearly USD 1,922 million of this market in 2024.
  • Nelipepimut-S for Early-Stage Breast Cancer: The global breast cancer market was valued at USD 38.41 billion in 2025 and is projected to reach USD 89.91 billion by 2034. North America dominated the breast cancer market in 2024.

AI Analysis | Feedback

SELLAS Life Sciences (SLS) is a late-stage biopharmaceutical company with no current product revenue; therefore, its future revenue growth over the next 2-3 years is primarily dependent on the successful clinical development, regulatory approval, and commercialization of its lead product candidates. Key drivers of future revenue growth for SELLAS Life Sciences include:
  1. Commercialization of Galinpepimut-S (GPS) for Acute Myeloid Leukemia (AML) in the United States: The most significant anticipated driver is the potential U.S. regulatory approval and subsequent commercial launch of galinpepimut-S (GPS). GPS is currently in a pivotal Phase 3 REGAL trial for AML as maintenance therapy following second complete remission. Analysts' forecasts for substantial revenue beginning in 2026, reaching billions in subsequent years, indicate an expectation of successful product launch and sales for GPS.
  2. Advancement and Potential Commercialization of SLS009 in AML: The progression and potential regulatory approval of SLS009, a highly selective CDK9 inhibitor, for AML indications represent another crucial revenue driver. SLS009 has demonstrated positive Phase 2 data in relapsed/refractory AML, and a new randomized Phase 2 trial evaluating it in newly diagnosed, first-line AML patients commenced enrollment in early 2026. Successful outcomes from these trials could lead to accelerated regulatory approvals and market entry within the projected timeframe.
  3. Expansion into New Geographic Markets and Additional Cancer Indications through Strategic Collaborations: SELLAS's strategic partnerships could drive future revenue by expanding the market reach and therapeutic applications of its product candidates. This includes the existing collaboration with Merck & Co. to evaluate GPS in combination with pembrolizumab across various hematologic malignancies and solid tumors, which could lead to expanded indications. Furthermore, the agreement with IMPACT-AML to extend the SLS009 clinical program into Europe aims to broaden patient access and establish a foundation for potential European commercialization.
  4. Achievement of Milestone Payments from Strategic Partnerships: As a clinical-stage company, SELLAS's revenue growth can also be fueled by milestone payments triggered by the successful achievement of clinical development, regulatory, or commercial milestones from its various strategic collaborations. For example, the agreement with 3D Medicines for GPS commercialization in China includes potential future bonuses up to $191.5 million.

AI Analysis | Feedback

Share Issuance

  • SELLAS completed multiple registered direct offerings in 2024, resulting in approximately $66.3 million in net proceeds through the issuance of common stock, pre-funded warrants, and accompanying warrants.
  • In 2025, the company received a total of approximately $54.6 million in gross proceeds from the immediate exercise of existing warrants.
  • Subsequent to December 31, 2025, SELLAS received approximately $42.6 million in cash proceeds from common stock warrant exercises.

Inbound Investments

  • SELLAS received approximately $42.6 million in cash from common stock warrant exercises after December 31, 2025.
  • The company received approximately $54.6 million in gross proceeds from warrant exercises in September and October 2025.
  • In January 2025, SELLAS closed a $25 million registered direct offering with a single healthcare-focused institutional investor.

Latest Trefis Analyses

TitleDate
0DASHBOARDS 
1SELLAS Life Sciences Earnings Notes12/16/2025
Title
0ARTICLES

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

SLSKURATCRXAGENMRKRIMMXMedian
NameSELLAS L.Kura Onc.TScan Th.Agenus Marker T.Immix Bi. 
Mkt Price8.5310.360.873.041.379.405.79
Mkt Cap1.50.90.10.10.00.50.3
Rev LTM0729124005
Op Inc LTM-31-318-1298-12-36-34
FCF LTM-28-84-125-88-8-33-59
FCF 3Y Avg-32-37-106-149-12-20-34
CFO LTM-28-78-122-88-8-32-55
CFO 3Y Avg-31-35-103-146-12-19-33

Growth & Margins

SLSKURATCRXAGENMRKRIMMXMedian
NameSELLAS L.Kura Onc.TScan Th.Agenus Marker T.Immix Bi. 
Rev Chg LTM-5.4%106.7%24.5%--24.5%
Rev Chg 3Y Avg--7.3%18.7%--13.0%
Rev Chg Q-29.5%-54.8%40.2%--29.5%
QoQ Delta Rev Chg LTM-6.2%-11.5%8.5%--6.2%
Op Inc Chg LTM-12.6%-56.2%7.9%107.4%8.8%-65.7%-2.4%
Op Inc Chg 3Y Avg-8.8%-31.6%-22.8%54.0%7.8%-61.1%-15.8%
Op Mgn LTM--443.5%-1,408.7%6.3%---443.5%
Op Mgn 3Y Avg---1,752.6%-61.6%---907.1%
QoQ Delta Op Mgn LTM-6.4%-93.4%24.3%--6.4%
CFO/Rev LTM--108.9%-1,335.5%-70.7%---108.9%
CFO/Rev 3Y Avg---1,494.3%-114.5%---804.4%
FCF/Rev LTM--117.9%-1,367.7%-70.7%---117.9%
FCF/Rev 3Y Avg---1,546.9%-116.3%---831.6%

Valuation

SLSKURATCRXAGENMRKRIMMXMedian
NameSELLAS L.Kura Onc.TScan Th.Agenus Marker T.Immix Bi. 
Mkt Cap1.50.90.10.10.00.50.3
P/S-12.812.40.9--12.4
P/Op Inc-46.8-2.9-0.914.8-2.3-14.4-2.6
P/EBIT-46.8-3.1-0.91.0-2.3-14.4-2.7
P/E-49.9-3.1-0.91.8-2.4-14.9-2.8
P/CFO-52.2-11.8-0.9-1.3-3.3-16.2-7.6
Total Yield-2.0%-32.1%-110.0%56.0%-41.2%-6.7%-19.4%
Dividend Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg-37.5%-0.1%-57.9%-185.3%-53.7%-17.3%-45.6%
D/E0.00.00.80.40.00.00.0
Net D/E-0.1-0.6-0.30.1-0.6-0.2-0.2

Returns

SLSKURATCRXAGENMRKRIMMXMedian
NameSELLAS L.Kura Onc.TScan Th.Agenus Marker T.Immix Bi. 
1M Rtn9.6%-7.9%-18.4%-2.3%-2.1%7.1%-2.2%
3M Rtn55.7%24.5%-16.8%-17.6%4.6%6.7%5.6%
6M Rtn223.1%-8.1%-4.0%-13.4%-3.5%61.8%-3.7%
12M Rtn453.9%77.1%-39.9%-36.4%-5.5%319.6%35.8%
3Y Rtn410.8%-5.0%-68.0%-91.2%-67.8%260.2%-36.4%
1M Excs Rtn-5.4%-0.3%-13.6%-4.0%-3.4%4.6%-3.7%
3M Excs Rtn64.4%10.6%-31.7%-32.9%-12.6%-11.7%-12.1%
6M Excs Rtn293.1%-9.4%-18.0%-26.5%-4.1%57.9%-6.8%
12M Excs Rtn418.4%46.0%-65.7%-56.9%-31.7%268.4%7.1%
3Y Excs Rtn343.0%-80.6%-138.5%-162.6%-114.5%292.2%-97.6%

Comparison Analyses

null

Financials

Segment Financials

Revenue by Segment
$ Mil2023202220212020
Development of novel therapeutics for a broad range of cancer indications0182
Total0182


Assets by Segment
$ Mil20252024202320222021
Development of novel therapeutics for a broad range of cancer indications781962126
Total781962126


Price Behavior

Price Behavior
Market Price$8.53 
Market Cap ($ Bil)1.5 
First Trading Date03/12/2008 
Distance from 52W High-8.4% 
   50 Days200 Days
DMA Price$6.59$3.93
DMA Trendupup
Distance from DMA29.5%116.9%
 3M1YR
Volatility109.7%95.9%
Downside Capture400.98134.18
Upside Capture383.79299.87
Correlation (SPY)50.2%25.1%
SLS Betas & Captures as of 5/31/2026

 1M2M3M6M1Y3Y
Beta5.763.493.582.491.700.80
Up Beta10.823.032.652.081.550.71
Down Beta5.020.792.711.040.660.47
Up Capture965%683%795%1300%768%220%
Bmk +ve Days13283667141432
Stock +ve Days14243473126350
Down Capture-173%258%291%101%116%95%
Bmk -ve Days7132757109318
Stock -ve Days6152748114349

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with SLS
SLS434.3%96.2%2.18-
Sector ETF (XLV)14.7%15.0%0.7016.0%
Equity (SPY)26.1%12.4%1.5924.7%
Gold (GLD)24.1%27.5%0.7713.7%
Commodities (DBC)18.5%18.8%0.77-18.8%
Real Estate (VNQ)11.8%13.8%0.5712.3%
Bitcoin (BTCUSD)-40.2%42.5%-1.0915.6%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with SLS
SLS-7.6%95.3%0.39-
Sector ETF (XLV)5.5%14.7%0.1918.5%
Equity (SPY)13.4%17.1%0.6121.0%
Gold (GLD)17.1%18.3%0.766.5%
Commodities (DBC)7.5%19.4%0.28-1.3%
Real Estate (VNQ)2.1%18.9%0.0117.9%
Bitcoin (BTCUSD)9.4%54.1%0.3717.4%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with SLS
SLS-59.0%130.7%-0.09-
Sector ETF (XLV)9.5%16.6%0.468.9%
Equity (SPY)15.4%18.0%0.7311.0%
Gold (GLD)12.2%16.1%0.624.0%
Commodities (DBC)6.0%18.0%0.263.1%
Real Estate (VNQ)5.4%20.7%0.238.7%
Bitcoin (BTCUSD)59.9%66.8%1.007.7%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date5292026
Short Interest: Shares Quantity61.0 Mil
Short Interest: % Change Since 51520266.9%
Average Daily Volume13.8 Mil
Days-to-Cover Short Interest4.4 days
Basic Shares Quantity172.5 Mil
Short % of Basic Shares35.4%

Earnings Returns History

Updated 6/15/2026
Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
5/12/202625.1%45.4%48.5%
3/19/2026-8.5%-4.8%-4.0%
11/12/2025-2.0%2.0%36.9%
8/12/2025-3.7%5.6%17.4%
5/13/20257.1%37.6%17.0%
3/20/2025-0.8%-4.1%6.6%
11/13/20240.0%-2.4%-31.3%
8/13/20240.8%10.1%11.8%
...
SUMMARY STATS   
# Positive101213
# Negative141211
Median Positive6.5%14.4%19.8%
Median Negative-3.3%-10.6%-5.4%
Max Positive25.1%49.4%176.0%
Max Negative-44.0%-42.9%-46.8%
Collapse to Preview
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
5/12/202625.1%45.4%48.5%
3/19/2026-8.5%-4.8%-4.0%
11/12/2025-2.0%2.0%36.9%
8/12/2025-3.7%5.6%17.4%
5/13/20257.1%37.6%17.0%
3/20/2025-0.8%-4.1%6.6%
11/13/20240.0%-2.4%-31.3%
8/13/20240.8%10.1%11.8%
5/14/20247.3%3.6%5.8%
3/28/20245.9%32.7%19.8%
11/9/2023-0.2%1.2%13.2%
8/10/2023-1.4%-9.6%-3.8%
5/11/2023-11.1%-0.6%-3.5%
3/16/2023-2.2%-11.6%20.3%
11/14/2022-44.0%-42.9%-46.8%
8/11/2022-2.8%4.7%-1.3%
5/12/202210.4%49.4%-5.4%
11/12/2021-18.5%-22.0%-27.2%
8/12/20211.6%-17.2%-2.6%
5/13/20217.1%25.5%62.8%
3/23/2021-17.8%-18.9%-21.6%
1/14/2021-0.7%-1.5%67.1%
11/13/20200.4%18.6%176.0%
8/13/2020-11.0%-22.3%-36.3%
SUMMARY STATS   
# Positive101213
# Negative141211
Median Positive6.5%14.4%19.8%
Median Negative-3.3%-10.6%-5.4%
Max Positive25.1%49.4%176.0%
Max Negative-44.0%-42.9%-46.8%

SEC Filings

Expand for More
Report DateFiling DateFiling
03/31/202605/12/202610-Q
12/31/202503/19/202610-K
09/30/202511/12/202510-Q
06/30/202508/12/202510-Q
03/31/202505/13/202510-Q
12/31/202403/20/202510-K
09/30/202411/13/202410-Q
06/30/202408/13/202410-Q
03/31/202405/14/202410-Q
12/31/202303/28/202410-K
09/30/202311/09/202310-Q
06/30/202308/10/202310-Q
03/31/202305/11/202310-Q
12/31/202203/16/202310-K
09/30/202211/14/202210-Q
06/30/202208/11/202210-Q
Collapse to Preview
Report DateFiling DateFiling
03/31/202605/12/202610-Q
12/31/202503/19/202610-K
09/30/202511/12/202510-Q
06/30/202508/12/202510-Q
03/31/202505/13/202510-Q
12/31/202403/20/202510-K
09/30/202411/13/202410-Q
06/30/202408/13/202410-Q
03/31/202405/14/202410-Q
12/31/202303/28/202410-K
09/30/202311/09/202310-Q
06/30/202308/10/202310-Q
03/31/202305/11/202310-Q
12/31/202203/16/202310-K
09/30/202211/14/202210-Q
06/30/202208/11/202210-Q
03/31/202205/12/202210-Q
12/31/202103/31/202210-K
09/30/202111/12/202110-Q
06/30/202108/12/202110-Q
03/31/202105/13/202110-Q
12/31/202003/23/202110-K
09/30/202011/13/202010-Q
06/30/202008/13/202010-Q
03/31/202005/14/202010-Q
12/31/201903/13/202010-K
09/30/201911/14/201910-Q
06/30/201908/14/201910-Q

Recent Forward Guidance

Updated 6/1/2026

Latest: Q1 2026 Earnings Reported 5/12/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2026 Capital Raising Capacity 150.00 Mil    

Prior: Q4 2025 Earnings Reported 3/19/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
Q2 2026 Patient Enrollment 40    

Insider Activity

Updated 6/18/2026
Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Kalin, Katherine BachDirectBuy112120251.5963,400100,806165,996Form
2Van, Nostrand Robert LDirectBuy61320251.4810,00014,80030,192Form
3Wasman, JaneDirectBuy60220251.6920,00033,80051,376Form
Collapse to Preview
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Kalin, Katherine BachDirectBuy112120251.5963,400100,806165,996Form
2Van, Nostrand Robert LDirectBuy61320251.4810,00014,80030,192Form
3Wasman, JaneDirectBuy60220251.6920,00033,80051,376Form
Core Cache Last Updated: 6/22/2026