Satellos Bioscience (MSLE)


Market Price (8/8/2026): $9.91 | Market Cap: $182.7 MilSector: Health Care | Industry: Biotechnology

Satellos Bioscience (MSLE)


Market Price (8/8/2026): $9.91
Market Cap: $182.7 Mil
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -38%

Megatrend and thematic drivers
Megatrends include Precision Medicine, and Biotechnology & Genomics. Themes include Biopharmaceutical R&D, Targeted Therapies, Show more.

Weak multi-year price returns
3Y Excs Rtn is -6.5%

Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0

Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -30 Mil

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -20%

Key risks
MSLE key risks include [1] the company's singular dependence on the clinical trial success and regulatory approval of its lead drug candidate, Show more.

0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -38%
1 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Biotechnology & Genomics. Themes include Biopharmaceutical R&D, Targeted Therapies, Show more.
2 Weak multi-year price returns
3Y Excs Rtn is -6.5%
3 Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
4 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -30 Mil
5 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -20%
6 Key risks
MSLE key risks include [1] the company's singular dependence on the clinical trial success and regulatory approval of its lead drug candidate, Show more.

Valuation & Metrics

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Updated on 8/1/2026

Satellos Bioscience (MSLE) stock has gained about 25% since 4/30/2026 because of the following key factors:

1. Positive Six-Month Interim Data from Phase 2 TRAILHEAD Study.

On July 8, 2026, Satellos Bioscience announced positive six-month interim data from its Phase 2 TRAILHEAD study for SAT-3247 in adult patients with Duchenne Muscular Dystrophy (DMD). The data indicated reduced muscle fat fraction, increased effort, stable strength, lower creatine kinase (CK) levels, and a favorable safety profile.

2. FDA Fast Track Designation for SAT-3247.

Satellos received Fast Track designation from the U.S. Food and Drug Administration (FDA) for SAT-3247 for the treatment of DMD on June 29, 2026. This designation is granted to therapies that address serious conditions and have the potential to fulfill an unmet medical need, aiming to accelerate the development and review process.

Show more
Updated on 8/1/2026

Satellos Bioscience (MSLE) stock has gained about 25% since 4/30/2026 because of the following key factors:

1. Positive Six-Month Interim Data from Phase 2 TRAILHEAD Study.

On July 8, 2026, Satellos Bioscience announced positive six-month interim data from its Phase 2 TRAILHEAD study for SAT-3247 in adult patients with Duchenne Muscular Dystrophy (DMD). The data indicated reduced muscle fat fraction, increased effort, stable strength, lower creatine kinase (CK) levels, and a favorable safety profile.

2. FDA Fast Track Designation for SAT-3247.

Satellos received Fast Track designation from the U.S. Food and Drug Administration (FDA) for SAT-3247 for the treatment of DMD on June 29, 2026. This designation is granted to therapies that address serious conditions and have the potential to fulfill an unmet medical need, aiming to accelerate the development and review process.

3. Analyst Upgrades and Increased Price Targets.

Following the positive clinical trial data, investment analysts revised their ratings and price targets for MSLE. On July 9, 2026, H.C. Wainwright raised its price target for Satellos Bioscience from $11 to $18 while maintaining a "Buy" rating. The consensus among 7 investment analysts shifted to a "Moderate Buy" rating by July 2026, a change from a "Hold" consensus rating in April 2026. The average price target from these analysts stood at $19.75, representing a potential upside of approximately 101.9% from the stock's closing price of $9.78 as of July 24, 2026.

4. Investor Optimism Despite Q1 Fiscal 2026 Loss.

Satellos Bioscience reported its financial results for fiscal Q1 2026 (ended March 31, 2026) on May 15, 2026, with a wider net loss per share of -$0.53, missing the Zacks Consensus Estimate of -$0.51. Despite the negative earnings surprise, the stock rose 19.4% in the trading session, reflecting investor focus on the advancement of its pipeline, particularly SAT-3247, rather than the near-term financial performance. The company also confirmed it had raised $57 million, providing operational funding through 2027, and that its BASECAMP study was on track to complete enrollment in fiscal Q3 2026.

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Stock Movement Drivers

Fundamental Drivers

The 26.2% change in MSLE stock from 4/30/2026 to 8/7/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)43020268072026Change
Stock Price ($)7.9510.0326.2%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)1518-16.1%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

4/30/2026 to 8/7/2026
ReturnCorrelation
MSLE26.2% 
Market (SPY)7.6%24.5%
Sector (XLV)13.5%-6.4%

Fundamental Drivers

The -9.4% change in MSLE stock from 1/31/2026 to 8/7/2026 was primarily driven by a -24.4% change in the company's Shares Outstanding (Mil).
(LTM values as of)13120268072026Change
Stock Price ($)11.0810.03-9.4%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)1418-24.4%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2026 to 8/7/2026
ReturnCorrelation
MSLE-9.4% 
Market (SPY)12.1%27.1%
Sector (XLV)7.5%11.3%

Fundamental Drivers

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Market Drivers

7/31/2025 to 8/7/2026
ReturnCorrelation
MSLE  
Market (SPY)23.4%24.6%
Sector (XLV)28.7%11.3%

Fundamental Drivers

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Market Drivers

7/31/2023 to 8/7/2026
ReturnCorrelation
MSLE  
Market (SPY)74.9%24.6%
Sector (XLV)29.3%11.3%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
MSLE Return-----66%66%
Peers Return-7%32%-21%-50%56%2547480%1909342%
S&P 500 Return27%-19%24%23%16%13%105%

Monthly Win Rates [3]
MSLE Win Rate-----75% 
Peers Win Rate42%67%46%34%46%31% 
S&P 500 Win Rate75%42%67%75%67%50% 

Max Drawdowns [4]
MSLE Max Drawdown------ 
Peers Max Drawdown-27%-19%-12%-62%-64%-58% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: VRTX, APMD, ATTO, BLSM, BRVE.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 8/7/2026 (YTD)

How Low Can It Go

MSLE has limited trading history. Below is the Health Care sector ETF (XLV) in its place.

EventXLVS&P 500
2025 US Tariff Shock
  % Loss-11.7%-18.8%
  % Gain to Breakeven13.3%23.1%
  Time to Breakeven142 days79 days
2022 Inflation Shock & Fed Tightening
  % Loss-13.8%-24.5%
  % Gain to Breakeven15.9%32.4%
  Time to Breakeven166 days427 days
2020 COVID-19 Crash
  % Loss-27.9%-33.7%
  % Gain to Breakeven38.8%50.9%
  Time to Breakeven77 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-15.0%-19.2%
  % Gain to Breakeven17.6%23.8%
  Time to Breakeven191 days105 days
2015-2016 China Devaluation / Global Growth Scare
  % Loss-15.9%-12.2%
  % Gain to Breakeven18.9%13.9%
  Time to Breakeven165 days62 days
2011 US Debt Ceiling Crisis & European Contagion
  % Loss-15.8%-17.9%
  % Gain to Breakeven18.8%21.8%
  Time to Breakeven153 days123 days

Compare to VRTX, ATYR, AVLN, CNXU, COAG

In The Past

State Street Health Care Select Sector SPDR ETF's stock fell -11.7% during the 2025 US Tariff Shock. Such a loss loss requires a 13.3% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

MSLE has limited trading history. Below is the Health Care sector ETF (XLV) in its place.

EventXLVS&P 500
2020 COVID-19 Crash
  % Loss-27.9%-33.7%
  % Gain to Breakeven38.8%50.9%
  Time to Breakeven77 days140 days
2008-2009 Global Financial Crisis
  % Loss-37.9%-53.4%
  % Gain to Breakeven61.1%114.4%
  Time to Breakeven767 days1085 days

Compare to VRTX, ATYR, AVLN, CNXU, COAG

In The Past

State Street Health Care Select Sector SPDR ETF's stock fell -11.7% during the 2025 US Tariff Shock. Such a loss loss requires a 13.3% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Satellos Bioscience (MSLE)

Satellos Bioscience (MSLE) is a Canadian biotechnology company focused on developing a novel class of therapeutics aimed at regenerating muscle tissue. Leveraging an innovative artificial intelligence (AI)-driven discovery platform, Satellos explores the intricate biology of muscle stem cells. Their core mission is to discover and develop small molecule drugs that restore the natural muscle repair mechanisms within the body, offering a new approach to treating muscle degenerative diseases.

The company's primary strategy revolves around modulating the muscle stem cell niche, effectively "re-awakening" or optimizing the body's intrinsic ability to repair and rebuild muscle. Their lead program targets Duchenne Muscular Dystrophy (DMD), a severe, rare genetic disorder characterized by progressive muscle degeneration and weakness. By focusing on selective modulation of muscle stem cells, Satellos aims to provide therapies that address the root cause of muscle loss rather than just managing symptoms.

Satellos Bioscience primarily serves the pharmaceutical market, with a specific focus on developing treatments for patients afflicted with debilitating muscle degenerative diseases, beginning with rare disorders like DMD. Their potential customers are patients and healthcare providers seeking transformative therapies for conditions where current treatments are limited or insufficient. Ultimately, Satellos seeks to establish itself as a leader in regenerative medicine, providing innovative solutions for a broad range of muscle-related conditions.

AI Analysis | Feedback

Here are 1-3 brief analogies to describe Satellos Bioscience:

  • Sarepta Therapeutics for Duchenne muscle regeneration.

  • Vertex Pharmaceuticals for muscle stem cell therapies.

AI Analysis | Feedback

  • SAT-3157: This is their lead oral small molecule drug candidate designed to modulate muscle stem cell regeneration for the treatment of Duchenne muscular dystrophy (DMD) and other muscle disorders.
  • MyoReGenX™ Platform: This proprietary drug discovery platform is used to identify and develop small molecules that specifically modulate muscle stem cell behavior for therapeutic applications in muscle diseases.

AI Analysis | Feedback

Satellos Bioscience (MSLE) is a biotechnology company focused on the discovery and development of small molecule therapeutics that modulate muscle stem cell function for the treatment of muscle diseases, such as Duchenne muscular dystrophy (DMD). As a pre-clinical and early clinical-stage drug development company, Satellos Bioscience does not currently have major customers that purchase its products or services in the traditional sense.

Its business model is centered on research and development, aiming to develop proprietary drug candidates. Revenue typically comes from equity financing, grants, and potentially future licensing agreements or partnerships with larger pharmaceutical companies if their drug candidates advance through clinical trials.

Therefore, Satellos Bioscience does not have identifiable major customer companies or categories of individual customers to report at this stage of its operations.

AI Analysis | Feedback

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AI Analysis | Feedback

Satellos Bioscience Management Team

Frank Gleeson, MBA

Co-founder, Chief Executive Officer, & Board Director

Mr. Gleeson has been instrumental in building over 20 biomedical companies from breakthrough research and technologies, negotiating numerous financing and M&A transactions valued at more than $500 million. Prior to co-founding Satellos, he co-founded Verio Therapeutics with Dr. Rudnicki, serving as CEO and managing its acquisition by Fate Therapeutics (Nasdaq: FATE). He was Chief Commercial Operations at the Centre for Probe Development and Commercialization (CPDC), where he played a key role in building a global radiopharmaceutical manufacturing business and supported the creation of two spin-out companies. Mr. Gleeson also served as an Executive-in-Residence with the Fight Against Cancer Innovation Trust (FACIT), supporting or leading the creation, financing, and exits of three new entities. Earlier, he was the founding CEO of MDS Proteomics Inc., where he integrated three acquisitions, built a 200-person team, and raised over $100 million. He was also a Senior Vice President and Venture Partner with MDS Capital Corp. (now Lumira), managing a fund exceeding $250 million focused on creating drug discovery companies based on novel Canadian science.

Elizabeth Williams, CPA, CA

Chief Financial Officer

Ms. Williams was appointed Chief Financial Officer of Satellos on September 5, 2023, bringing nearly 20 years of experience in biotech, working with publicly listed entities in both Canada and the United States. Before joining Satellos, she served as CFO of Medicenna (Nasdaq: MDNA), where she oversaw all financial, legal, and investor relations functions and guided the company's uplisting to the TSX and Nasdaq. She also held several positions at Aptose Biosciences Inc. (Nasdaq: APTO), including Vice President of Finance and Administration and Acting CFO, with responsibilities spanning financings, financial reporting, and regulatory compliance. Ms. Williams is also a Director and Chair of the Audit Committee of Triumvira Immunologics Inc.

Michael Rudnicki, OC, Ph.D., FRS, FRSC

Co-founder and Chief Discovery Officer

Dr. Rudnicki is a co-founder of Satellos and is recognized globally as a leading scientific authority on muscle stem cell function and their role in muscle regeneration. His research led to a landmark 2007 Cell paper and a 2016 Nature Medicine paper, which provided foundational insights into muscle stem cells and the role of the dystrophin protein in muscle regeneration. He currently serves as the Scientific Director of the Canadian Stem Cell Network and Director of the Regenerative Medicine Program at the Ottawa Hospital Research Institute, in addition to being a Professor in the Faculty of Medicine at the University of Ottawa.

Wildon Farwell, M.D., MPH

Chief Medical Officer

Dr. Farwell possesses over a decade of leadership experience in clinical development and medical affairs, with a deep specialization in neuromuscular and rare diseases. Before joining Satellos, he served as Chief Medical Officer and later as a Medical Advisor at Dyne Therapeutics, where he established and led the development organization. At Dyne, he was responsible for overseeing protocol design, regulatory strategy for programs in Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1), and guiding the execution of multiple clinical trials. He has been directly involved in leading multiple product development programs, including two novel drugs approved by the FDA for ALS and spinal muscular atrophy.

Phil Lambert, Ph.D.

Chief Scientific Officer

Dr. Lambert brings extensive leadership experience to Satellos, having held significant positions at various pharmaceutical and biotechnology companies. His career includes roles at Centogene, Life Biosciences, Sirtris Pharmaceuticals, Forum Pharmaceuticals, ALS Therapy Development Institute, Regeneron Pharmaceuticals, GSK, and Parke Davis. He also served as a faculty member in the Department of Psychiatry at Emory University School of Medicine.

AI Analysis | Feedback

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  • Clinical Trial and Regulatory Approval Risk: The success of Satellos Bioscience is heavily dependent on the successful outcome of its preclinical and clinical trials for its drug candidate SAT-3247 and subsequent regulatory approvals from health authorities. As a biotechnology company, failure to demonstrate efficacy and safety, or to meet trial endpoints, could lead to a complete loss of investment.
  • Financial Sustainability and Funding Risk: As an early-stage, pre-revenue biotechnology company with zero current revenue and a negative earnings per share, Satellos Bioscience faces significant challenges in its financial metrics and ongoing operational costs, requiring continuous investment in research and development. The company's ability to raise additional funds when needed and to continue as a going concern is a key risk.
  • Market Competition Risk: Satellos Bioscience operates in a highly competitive pharmaceutical and bioscience industry, particularly in the market for therapeutic products to treat Duchenne muscular dystrophy and related diseases. This competition could impact the market acceptance and commercialization of its products, even if approved.
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AI Analysis | Feedback

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AI Analysis | Feedback

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Satellos Bioscience (symbol: MSLE) is developing SAT-3247, an oral small molecule drug candidate, as a potential treatment for Duchenne Muscular Dystrophy (DMD) and other degenerative muscle diseases.

The addressable market for Duchenne Muscular Dystrophy (DMD) treatments is substantial:

  • The global Duchenne Muscular Dystrophy treatment market size was valued at approximately USD 4.63 billion in 2025. This market is projected to grow to USD 19.18 billion by 2034, with a Compound Annual Growth Rate (CAGR) of 17.1% during this forecast period.
  • Another estimate places the global Duchenne Muscular Dystrophy drugs market size at USD 3.9 billion in 2025, with an anticipated growth to USD 6.5 billion by 2034, demonstrating a CAGR of 10.96%.
  • In 2023, the Duchenne Muscular Dystrophy market size in the 7 Major Markets (7MM) was approximately USD 2,150 million.
  • For the U.S. alone, the Duchenne Muscular Dystrophy patient population is around 12,000, and the market opportunity exceeds USD 4 billion.
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AI Analysis | Feedback

Satellos Bioscience (symbol: MSLE) is a clinical-stage biotechnology company focused on developing therapies for degenerative muscle diseases, primarily Duchenne muscular dystrophy (DMD). Given its current stage of development, the company is not yet generating significant product revenue. Therefore, the drivers of future revenue growth over the next 2-3 years are intrinsically tied to the advancement of its drug pipeline and the establishment of strategic partnerships.

Here are 3-5 expected drivers of future revenue growth for Satellos Bioscience over the next 2-3 years:

  1. Successful Advancement of SAT-3247 in Clinical Trials: The primary driver of future revenue potential is the successful progression of its lead drug candidate, SAT-3247, through ongoing and upcoming clinical trials. Positive interim and final data from the Phase 2 TRAILHEAD trial for adult Duchenne muscular dystrophy and the BASECAMP pediatric DMD Phase 2 trial are critical. Full enrollment for the BASECAMP trial is anticipated in the second quarter of 2026, with interim data expected in the coming months and final data in the first half of 2027. These positive results are essential for demonstrating the drug's efficacy and safety, which would significantly enhance its attractiveness for potential licensing deals or eventual commercialization.
  2. Securing Strategic Partnerships and Licensing Agreements: As a clinical-stage company, Satellos Bioscience is likely to generate revenue through collaborations with larger pharmaceutical companies. Such partnerships could involve upfront payments, milestone payments tied to clinical and regulatory achievements, and future royalties on product sales. An analyst report projects SAT-3247 royalty revenue potentially beginning in fiscal year 2030, which would be a direct outcome of successful development and partnerships initiated within or following the 2-3 year timeframe.
  3. Expansion of the Therapeutic Pipeline through MyoReGenX™ Platform: Satellos Bioscience utilizes its proprietary MyoReGenX™ platform to identify and develop novel drug candidates for various degenerative muscle diseases. Further leveraging this platform to discover and advance additional therapies beyond SAT-3247 into preclinical or clinical development would broaden the company's long-term revenue potential by creating new assets for partnership or independent development. The company aims to build a pipeline of novel therapeutics to correct muscle stem cell polarity and promote the body's innate muscle repair and regeneration process.

AI Analysis | Feedback

Share Issuance

  • Satellos Bioscience completed a public offering in February 2026, generating approximately US$57.2 million in gross proceeds from the sale of 5,168,019 common shares and pre-funded warrants to purchase 495,049 common shares.
  • The common shares were sold at a price of US$10.10 per share, and the pre-funded warrants at US$10.09999 per pre-funded warrant.
  • The company previously announced the pricing of a public offering of approximately US$50 million in February 2026, which included 4,455,445 common shares and pre-funded warrants for 495,049 common shares.

Inbound Investments

  • In February 2026, Satellos Bioscience completed a public offering, securing approximately US$57.2 million in gross proceeds.
  • Franklin Berger and Mark Nawacki, members of the company's board of directors, participated in the February 2026 offering, purchasing 24,750 and 30,000 common shares, respectively.

Capital Expenditures

  • In the last 12 months (prior to March 2026), capital expenditures were -$6,000.
  • Satellos Bioscience Inc.'s capital expenditure for 2025 was CAD -3.0 thousand.
  • The net proceeds from the February 2026 offering are primarily allocated to funding ongoing research and development activities, including advancing the SAT-3247 program through clinical trials (Phase 2 to Phase 3), and for other discovery-stage or pre-clinical development programs, as well as for working capital and general corporate purposes.

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

MSLEVRTXAPMDATTOBLSMBRVEMedian
NameSatellos.Vertex P.Apnimed Attovia .BlossomH.Bravehea. 
Mkt Price10.03496.0727.0020.1716.0030.0023.59
Mkt Cap0.2125.9----63.0
Rev LTM012,587----6,294
Op Inc LTM-304,777----2,373
FCF LTM-263,796----1,885
FCF 3Y Avg-201,957----968
CFO LTM-264,293----2,134
CFO 3Y Avg-202,398----1,189

Growth & Margins

MSLEVRTXAPMDATTOBLSMBRVEMedian
NameSatellos.Vertex P.Apnimed Attovia .BlossomH.Bravehea. 
Rev Chg LTM-10.2%----10.2%
Rev Chg 3Y Avg-9.8%----9.8%
Rev Chg Q-12.5%----12.5%
QoQ Delta Rev Chg LTM-3.0%----3.0%
Op Inc Chg LTM-44.7%2,497.9%----1,226.6%
Op Inc Chg 3Y Avg-82.4%792.2%----354.9%
Op Mgn LTM-37.9%----37.9%
Op Mgn 3Y Avg-23.9%----23.9%
QoQ Delta Op Mgn LTM--0.2%-----0.2%
CFO/Rev LTM-34.1%----34.1%
CFO/Rev 3Y Avg-19.6%----19.6%
FCF/Rev LTM-30.2%----30.2%
FCF/Rev 3Y Avg-15.7%----15.7%

Valuation

MSLEVRTXAPMDATTOBLSMBRVEMedian
NameSatellos.Vertex P.Apnimed Attovia .BlossomH.Bravehea. 
Mkt Cap0.2125.9----63.0
P/S-10.0----10.0
P/Op Inc-6.226.3----10.1
P/EBIT-6.225.0----9.4
P/E-6.528.6----11.0
P/CFO-7.229.3----11.1
Total Yield-15.4%3.5%-----6.0%
Dividend Yield0.0%0.0%----0.0%
FCF Yield 3Y Avg-1.6%----1.6%
D/E0.00.0----0.0
Net D/E-0.4-0.0-----0.2

Returns

MSLEVRTXAPMDATTOBLSMBRVEMedian
NameSatellos.Vertex P.Apnimed Attovia .BlossomH.Bravehea. 
1M Rtn11.7%-0.5%8.0%20,169,900.0%0.0%0.7%4.3%
3M Rtn30.4%15.4%8.0%20,169,900.0%0.0%0.7%11.7%
6M Rtn-10.8%3.8%8.0%10,084,900.0%0.0%0.7%2.2%
12M Rtn65.4%32.1%8.0%20,169,900.0%0.0%0.7%20.0%
3Y Rtn65.4%44.0%8.0%25,594.3%0.0%0.7%26.0%
1M Excs Rtn3.4%-2.9%5.2%20,169,897.2%-2.8%-2.2%0.6%
3M Excs Rtn34.7%11.0%2.3%20,169,894.3%-5.7%-5.1%6.6%
6M Excs Rtn-29.9%-6.0%-6.1%10,084,885.9%-14.1%-13.4%-9.8%
12M Excs Rtn43.2%6.4%-14.3%20,169,877.7%-22.3%-21.6%-3.9%
3Y Excs Rtn-6.5%-33.5%-63.9%20,169,828.1%-71.9%-71.2%-48.7%

Comparison Analyses

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Financials

Segment Financials

Assets by Segment
$ Mil20252024202320222021
Research and development of small molecule drugcandidates to treat degenerative muscle diseases325133510
Total325133510


Price Behavior

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MSLE Betas & Captures as of 7/31/2026

 1M2M3M6M1Y3Y
Beta2.192.111.681.82-0.420.04
Up Beta4.451.241.620.34-0.870.50
Down Beta2.683.333.443.71-0.092.67
Up Capture365%361%161%175%134%13%
Bmk +ve Days11223567138427
Stock +ve Days122028546565
Down Capture-53%88%64%171%84%47%
Bmk -ve Days11212859114326
Stock -ve Days102133697474

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with MSLE
MSLE57.9%95.7%1.25-
Sector ETF (XLV)28.7%15.5%1.4211.1%
Equity (SPY)23.3%12.8%1.3624.4%
Gold (GLD)28.5%28.4%0.879.1%
Commodities (DBC)32.9%19.8%1.32-6.2%
Real Estate (VNQ)14.2%13.8%0.726.9%
Bitcoin (BTCUSD)-44.2%42.9%-1.234.0%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with MSLE
MSLE9.5%95.7%1.25-
Sector ETF (XLV)6.2%15.0%0.2311.1%
Equity (SPY)13.5%17.2%0.6124.4%
Gold (GLD)18.6%18.6%0.819.1%
Commodities (DBC)8.2%19.6%0.31-6.2%
Real Estate (VNQ)2.3%18.9%0.026.9%
Bitcoin (BTCUSD)8.8%53.0%0.354.0%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with MSLE
MSLE4.7%95.7%1.25-
Sector ETF (XLV)10.1%16.6%0.4911.1%
Equity (SPY)15.4%17.9%0.7324.4%
Gold (GLD)12.1%16.2%0.619.1%
Commodities (DBC)7.4%18.0%0.33-6.2%
Real Estate (VNQ)4.8%20.7%0.206.9%
Bitcoin (BTCUSD)58.2%66.2%0.984.0%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date7152026
Short Interest: Shares Quantity0.1 Mil
Short Interest: % Change Since 630202624.7%
Average Daily Volume0.1 Mil
Days-to-Cover Short Interest1
Basic Shares Quantity18.4 Mil
Short % of Basic Shares0.6%

Earnings Returns History

Updated 6/2/2026
Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
SUMMARY STATS   
# Positive000
# Negative000
Median Positive   
Median Negative   
Max Positive   
Max Negative   
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 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
SUMMARY STATS   
# Positive000
# Negative000
Median Positive   
Median Negative   
Max Positive   
Max Negative   

SEC Filings

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Report DateFiling DateFiling
03/31/202605/15/20266-K
12/31/202503/27/2026Annual
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Report DateFiling DateFiling
03/31/202605/15/20266-K
12/31/202503/27/2026Annual
Core Cache Last Updated: 8/7/2026