Tearsheet

Investment Highlights Why It Matters Which of these 2 stories sounds closer for this stock?

1. Generates cash flow

The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.

2. Riding a trend

Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow


0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -12%
Weak multi-year price returns
2Y Excs Rtn is -62%
Expensive valuation multiples
P/EPrice/Earnings or Price/(Net Income) is 25x
1 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 17%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 16%
  
2 Attractive yield
FCF Yield is 6.1%
  
3 Low stock price volatility
Vol 12M is 40%
  
4 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, Biopharmaceutical R&D, Show more.
  
0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -12%
1 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 17%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 16%
2 Attractive yield
FCF Yield is 6.1%
3 Low stock price volatility
Vol 12M is 40%
4 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, Biopharmaceutical R&D, Show more.
5 Weak multi-year price returns
2Y Excs Rtn is -62%
6 Expensive valuation multiples
P/EPrice/Earnings or Price/(Net Income) is 25x

Valuation, Metrics & Events

MDXG Stock


Why The Stock Moved


Qualitative Assessment

AI Generated Analysis | Feedback

Here are five key points highlighting why MiMedx (MDXG) stock moved by -3.4% during the approximate time period from August 31, 2025, to December 5, 2025: 1. Ongoing Uncertainty Regarding 2026 Medicare Reimbursement Changes. The primary factor influencing MiMedx's stock movement was the persistent uncertainty and anticipated impact of the CY 2026 Medicare Physician Fee Schedule Final Rule. This rule, finalized on November 3, 2025, was largely consistent with earlier proposals and is expected to introduce a fixed reimbursement rate for skin substitutes, potentially shrinking the market and challenging profit margins for companies like MiMedx.

2. Market Discounting of Positive Q3 2025 Results. Despite MiMedx reporting strong third-quarter 2025 financial results on October 29, 2025, beating both earnings and revenue estimates and raising full-year guidance, the market appeared to discount this positive news. Investors remained focused on the long-term risks posed by the upcoming Medicare reimbursement changes, with analysts noting that strong earnings did not fundamentally alter concerns about future demand and regulatory uncertainty.

Show more

Stock Movement Drivers

Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
MDXG Return20%-33%-54%215%10%-29%-9%
Peers Return6%-1%-7%-13%-25%3%-34%
S&P 500 Return16%27%-19%24%23%17%112%

Monthly Win Rates [3]
MDXG Win Rate17%67%33%67%50%20% 
Peers Win Rate29%21%25%27%15%40% 
S&P 500 Win Rate58%75%42%67%75%70% 

Max Drawdowns [4]
MDXG Max Drawdown-58%-39%-56%0%-37%-40% 
Peers Max Drawdown-19%-10%-17%-24%-25%-2% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: VRTX, ACSB, AIXC, ALPS, APRI.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 12/4/2025 (YTD)

How Low Can It Go

Unique KeyEventMDXGS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-83.4%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven501.9%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-58.2%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven139.1%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven267 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-86.6%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven645.2%24.7%
2018 CorrectionTime to BreakevenTime to BreakevenNot Fully Recovered days120 days
2008 Global Financial Crisis2008 Global Financial Crisis  
2008 Global Financial Crisis% Loss% Loss-92.2%-56.8%
2008 Global Financial Crisis% Gain to Breakeven% Gain to Breakeven1175.0%131.3%
2008 Global Financial CrisisTime to BreakevenTime to Breakeven1444 days1480 days

Compare to VRTX, ACSB, AIXC, ALPS, APRI


In The Past

MiMedx's stock fell -83.4% during the 2022 Inflation Shock from a high on 9/8/2021. A -83.4% loss requires a 501.9% gain to breakeven.

Preserve Wealth

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Asset Allocation

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About MiMedx (MDXG)

Better Bets than MiMedx (MDXG)

Trade Ideas

Select past ideas related to MDXG. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
10.0%10.0%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-7.7%-7.7%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
6.9%6.9%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
11.5%11.5%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
8.9%8.9%-5.1%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
10.0%10.0%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-7.7%-7.7%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
6.9%6.9%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
11.5%11.5%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
8.9%8.9%-5.1%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for MiMedx

Peers to compare with:

Financials

MDXGVRTXACSBAIXCALPSAPRIMedian
NameMiMedx Vertex P.Acesis AIxCryptoALPS Aprinoia. 
Mkt Price6.86457.36-2.631.17-4.75
Mkt Cap1.0116.9----59.0
Rev LTM39311,723-0--393
Op Inc LTM54-92--5---5
FCF LTM633,337--6--63
FCF 3Y Avg412,064--10--41
CFO LTM683,718--6--68
CFO 3Y Avg452,419--10--45

Growth & Margins

MDXGVRTXACSBAIXCALPSAPRIMedian
NameMiMedx Vertex P.Acesis AIxCryptoALPS Aprinoia. 
Rev Chg LTM14.8%10.3%----12.6%
Rev Chg 3Y Avg17.4%10.5%----13.9%
Rev Chg Q35.3%11.0%----23.1%
QoQ Delta Rev Chg LTM8.2%2.7%----5.4%
Op Mgn LTM13.7%-0.8%----6.5%
Op Mgn 3Y Avg14.3%26.2%----20.3%
QoQ Delta Op Mgn LTM1.8%1.0%----1.4%
CFO/Rev LTM17.2%31.7%----24.5%
CFO/Rev 3Y Avg12.5%23.1%----17.8%
FCF/Rev LTM16.1%28.5%----22.3%
FCF/Rev 3Y Avg11.2%19.8%----15.5%

Valuation

MDXGVRTXACSBAIXCALPSAPRIMedian
NameMiMedx Vertex P.Acesis AIxCryptoALPS Aprinoia. 
Mkt Cap1.0116.9----59.0
P/S2.68.5----5.6
P/EBIT19.022.4----20.7
P/E25.327.2----26.3
P/CFO15.226.9----21.1
Total Yield4.0%3.7%----3.8%
Dividend Yield0.0%0.0%----0.0%
FCF Yield 3Y Avg4.3%2.3%----3.3%
D/E0.00.0----0.0
Net D/E-0.1-0.0-----0.1

Returns

MDXGVRTXACSBAIXCALPSAPRIMedian
NameMiMedx Vertex P.Acesis AIxCryptoALPS Aprinoia. 
1M Rtn-10.8%8.5%--23.2%-8.5%
3M Rtn-3.2%15.2%----6.0%
6M Rtn8.2%3.1%----5.6%
12M Rtn-28.5%-1.4%-----14.9%
3Y Rtn119.2%44.0%----81.6%
1M Excs Rtn-12.1%7.2%--22.0%-7.2%
3M Excs Rtn-9.7%9.7%-----0.0%
6M Excs Rtn-7.3%-12.4%-----9.8%
12M Excs Rtn-40.3%-15.2%-----27.7%
3Y Excs Rtn48.7%-28.7%----10.0%

Financials

Segment Financials

Revenue by Segment

$ Mil20242023202220212020
Wound206    
Surgical116    
Wound & Surgical 268239  
Corporate & Other  3  
Regenerative Medicine  17  
Advanced Wound Care   209 
Other   8 
Section 351   32 
Single segment    299
Total321268259248299


Price Behavior

Short Interest

Short Interest: As Of Date11142025
Short Interest: Shares Quantity4,681,432
Short Interest: % Change Since 103120254.6%
Average Daily Volume1,038,901
Days-to-Cover Short Interest4.51
Basic Shares Quantity148,035,283
Short % of Basic Shares3.2%

SEC Filings

Expand for More

Report DateFiling DateFiling
93020251029202510-Q 9/30/2025
6302025730202510-Q 6/30/2025
3312025430202510-Q 3/31/2025
12312024226202510-K 12/31/2024
93020241030202410-Q 9/30/2024
6302024731202410-Q 6/30/2024
3312024430202410-Q 3/31/2024
12312023228202410-K 12/31/2023
93020231030202310-Q 9/30/2023
6302023801202310-Q 6/30/2023
3312023502202310-Q 3/31/2023
12312022228202310-K 12/31/2022
93020221102202210-Q 9/30/2022
6302022802202210-Q 6/30/2022
3312022503202210-Q 3/31/2022
12312021228202210-K 12/31/2021

Insider Activity

Expand for More

 OwnerTitleFiling DateActionPriceSharesTransacted
Value
Value of
Held Shares
Form
0Maersk-Moller KimberlyChief Commercial Officer11102025Sell7.4258,300432,3291,757,364Form