Inhibrx Biosciences (INBX)
Market Price (12/8/2025): $89.5 | Market Cap: $1.4 BilSector: Health Care | Industry: Biotechnology
Inhibrx Biosciences (INBX)
Market Price (12/8/2025): $89.5Market Cap: $1.4 BilSector: Health CareIndustry: Biotechnology
Investment Highlights
Why It Matters
Which of these 2 stories sounds closer for this stock?
1. Generates cash flow
The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.
2. Riding a trend
Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow
| Valuation becoming less expensiveP/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -66% | Trading close to highsDist 52W High is 0.0% | Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -154 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -11002% |
| Megatrend and thematic driversMegatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Biopharmaceutical R&D, Targeted Therapies, Show more. | Expensive valuation multiplesP/SPrice/Sales ratio is 989x | |
| Stock price has recently run up significantly6M Rtn6 month market price return is 543%, 12M Rtn12 month market price return is 470% | ||
| Weak revenue growthRev Chg LTMRevenue Change % Last Twelve Months (LTM) is -19% | ||
| Not cash flow generativeCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -10242%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -10246% | ||
| Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -15% | ||
| High stock price volatilityVol 12M is 120% |
| Valuation becoming less expensiveP/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -66% |
| Megatrend and thematic driversMegatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Biopharmaceutical R&D, Targeted Therapies, Show more. |
| Trading close to highsDist 52W High is 0.0% |
| Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -154 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -11002% |
| Expensive valuation multiplesP/SPrice/Sales ratio is 989x |
| Stock price has recently run up significantly6M Rtn6 month market price return is 543%, 12M Rtn12 month market price return is 470% |
| Weak revenue growthRev Chg LTMRevenue Change % Last Twelve Months (LTM) is -19% |
| Not cash flow generativeCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -10242%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -10246% |
| Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -15% |
| High stock price volatilityVol 12M is 120% |
Valuation, Metrics & Events
INBX Stock
Why The Stock Moved
Qualitative Assessment
AI Generated Analysis | Feedback
1. Positive Topline Results for Ozekibart (INBRX-109) in Chondrosarcoma: On October 23, 2025, Inhibrx Biosciences announced positive topline results from its registrational trial of Ozekibart (INBRX-109) in chondrosarcoma. The trial met its primary endpoint, demonstrating a statistically significant and clinically meaningful improvement in median progression-free survival compared to placebo.
2. Confirmation of Ozekibart's Efficacy and Safety Profile: The positive results for Ozekibart were consistent across all pre-specified subgroups, showing improved disease control and quality of life for patients. The company also highlighted a manageable safety profile for Ozekibart after mitigation measures.
Stock Movement Drivers
Return vs. Risk
Price Returns Compared
| 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total [1] | |
|---|---|---|---|---|---|---|---|
| Returns | |||||||
| INBX Return | - | - | - | - | - | 468% | 468% |
| Peers Return | 2% | -1% | 6% | 8% | -0% | 3% | 18% |
| S&P 500 Return | 16% | 27% | -19% | 24% | 23% | 17% | 112% |
Monthly Win Rates [3] | |||||||
| INBX Win Rate | - | - | - | - | 71% | 70% | |
| Peers Win Rate | 13% | 8% | 13% | 12% | 10% | 90% | |
| S&P 500 Win Rate | 58% | 75% | 42% | 67% | 75% | 70% | |
Max Drawdowns [4] | |||||||
| INBX Max Drawdown | - | - | - | - | - | -30% | |
| Peers Max Drawdown | -2% | -5% | 0% | -0% | -1% | -2% | |
| S&P 500 Max Drawdown | -31% | -1% | -25% | -1% | -2% | -15% | |
[1] Cumulative total returns since the beginning of 2020
[2] Peers: VRTX, AIXC, ALPS, BBOT, EVMN.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 12/5/2025 (YTD)
How Low Can It Go
INBX has limited trading history. Below is the Health Care sector ETF (XLV) in its place.
| Event | XLV | S&P 500 |
|---|---|---|
| 2022 Inflation Shock | ||
| % Loss | -16.1% | -25.4% |
| % Gain to Breakeven | 19.1% | 34.1% |
| Time to Breakeven | 599 days | 464 days |
| 2020 Covid Pandemic | ||
| % Loss | -28.8% | -33.9% |
| % Gain to Breakeven | 40.4% | 51.3% |
| Time to Breakeven | 116 days | 148 days |
| 2018 Correction | ||
| % Loss | -15.8% | -19.8% |
| % Gain to Breakeven | 18.8% | 24.7% |
| Time to Breakeven | 326 days | 120 days |
| 2008 Global Financial Crisis | ||
| % Loss | -40.6% | -56.8% |
| % Gain to Breakeven | 68.3% | 131.3% |
| Time to Breakeven | 1100 days | 1480 days |
Compare to
In The Past
SPDR Select Sector Fund's stock fell -16.1% during the 2022 Inflation Shock from a high on 4/8/2022. A -16.1% loss requires a 19.1% gain to breakeven.
Preserve Wealth
Limiting losses and compounding gains is essential to preserving wealth over time.
Asset Allocation
Actively managed asset allocation strategies protect wealth. Learn more.
Trade Ideas
Select past ideas related to INBX. For more, see Trefis Trade Ideas.
| Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
|---|---|---|---|---|---|---|---|
| 11142025 | CRL | Charles River Laboratories International | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 9.8% | 9.8% | -3.7% |
| 11142025 | GDRX | GoodRx | Dip Buy | DB | CFO/Rev | Low D/EDip Buy with High Cash Flow MarginsBuying dips for companies with significant cash flows from operations and reasonable debt / market cap | -8.8% | -8.8% | -11.8% |
| 11142025 | ASTH | Astrana Health | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 2.5% | 2.5% | -5.5% |
| 11142025 | SGRY | Surgery Partners | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 12.5% | 12.5% | -1.4% |
| 11072025 | TFX | Teleflex | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 10.1% | 10.1% | -5.1% |
| Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
|---|---|---|---|---|---|---|---|
| 11142025 | CRL | Charles River Laboratories International | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 9.8% | 9.8% | -3.7% |
| 11142025 | GDRX | GoodRx | Dip Buy | DB | CFO/Rev | Low D/EDip Buy with High Cash Flow MarginsBuying dips for companies with significant cash flows from operations and reasonable debt / market cap | -8.8% | -8.8% | -11.8% |
| 11142025 | ASTH | Astrana Health | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 2.5% | 2.5% | -5.5% |
| 11142025 | SGRY | Surgery Partners | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 12.5% | 12.5% | -1.4% |
| 11072025 | TFX | Teleflex | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 10.1% | 10.1% | -5.1% |
Research & Analysis
Invest in Strategies
Wealth Management
Peer Comparisons for Inhibrx Biosciences
| Peers to compare with: |
Financials
| Median | |
|---|---|
| Name | |
| Mkt Price | 17.79 |
| Mkt Cap | 1.4 |
| Rev LTM | 1 |
| Op Inc LTM | -92 |
| FCF LTM | -64 |
| FCF 3Y Avg | 1,028 |
| CFO LTM | -64 |
| CFO 3Y Avg | 1,205 |
Growth & Margins
| Median | |
|---|---|
| Name | |
| Rev Chg LTM | -4.5% |
| Rev Chg 3Y Avg | 10.5% |
| Rev Chg Q | 11.0% |
| QoQ Delta Rev Chg LTM | 1.3% |
| Op Mgn LTM | -700.7% |
| Op Mgn 3Y Avg | 26.2% |
| QoQ Delta Op Mgn LTM | 464.2% |
| CFO/Rev LTM | -635.6% |
| CFO/Rev 3Y Avg | 23.1% |
| FCF/Rev LTM | -636.5% |
| FCF/Rev 3Y Avg | 19.8% |
Valuation
| Median | |
|---|---|
| Name | |
| Mkt Cap | 1.4 |
| P/S | 498.8 |
| P/EBIT | -4.8 |
| P/E | -5.2 |
| P/CFO | -6.9 |
| Total Yield | -11.2% |
| Dividend Yield | 0.0% |
| FCF Yield 3Y Avg | 2.3% |
| D/E | 0.0 |
| Net D/E | -0.0 |
Returns
| Median | |
|---|---|
| Name | |
| 1M Rtn | 12.7% |
| 3M Rtn | 38.3% |
| 6M Rtn | 271.9% |
| 12M Rtn | 234.2% |
| 3Y Rtn | 41.8% |
| 1M Excs Rtn | 8.7% |
| 3M Excs Rtn | 18.6% |
| 6M Excs Rtn | 257.4% |
| 12M Excs Rtn | 234.5% |
| 3Y Excs Rtn | -24.4% |
Returns Analyses
Earnings Returns History
Expand for More| Forward Returns | |||
|---|---|---|---|
| Earnings Date | 1D Returns | 5D Returns | 21D Returns |
| 11/14/2025 | -2.2% | 6.1% | |
| 8/13/2025 | 1.6% | 3.6% | 16.8% |
| 3/17/2025 | 0.4% | 5.6% | -15.4% |
| 11/14/2024 | -3.5% | -2.4% | 1.6% |
| 8/13/2024 | -0.1% | 14.2% | 33.5% |
| SUMMARY STATS | |||
| # Positive | 2 | 4 | 3 |
| # Negative | 3 | 1 | 2 |
| Median Positive | 1.0% | 5.8% | 16.8% |
| Median Negative | -2.2% | -2.4% | -15.4% |
| Max Positive | 1.6% | 14.2% | 33.5% |
| Max Negative | -3.5% | -2.4% | -15.4% |
SEC Filings
Expand for More| Report Date | Filing Date | Filing |
|---|---|---|
| 9302025 | 11142025 | 10-Q 9/30/2025 |
| 6302025 | 8132025 | 10-Q 6/30/2025 |
| 3312025 | 5142025 | 10-Q 3/31/2025 |
| 12312024 | 3172025 | 10-K 12/31/2024 |
| 9302024 | 11142024 | 10-Q 9/30/2024 |
| 6302024 | 8132024 | 10-Q 6/30/2024 |
| 3312024 | 5152024 | 10-12B/A 3/31/2024 |
| 12312023 | 5082024 | 10-12B/A 12/31/2023 |
Insider Activity
Expand for More| Owner | Title | Filing Date | Action | Price | Shares | TransactedValue | Value ofHeld Shares | Form | |
|---|---|---|---|---|---|---|---|---|---|
| 0 | VIKING GLOBAL INVESTORS LP | 10092025 | Sell | 32.25 | 308,643 | 9,953,737 | 40,887,292 | Form |
Industry Resources
External Quote Links
| Y Finance | Barrons |
| TradingView | Morningstar |
| SeekingAlpha | ValueLine |
| Motley Fool | Robinhood |
| CNBC | Etrade |
| MarketWatch | Unusual Whales |
| YCharts | Perplexity Finance |
| FinViz |