Tearsheet

Inhibrx Biosciences (INBX)


Market Price (12/8/2025): $89.5 | Market Cap: $1.4 Bil
Sector: Health Care | Industry: Biotechnology

Inhibrx Biosciences (INBX)


Market Price (12/8/2025): $89.5
Market Cap: $1.4 Bil
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Which of these 2 stories sounds closer for this stock?

1. Generates cash flow

The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.

2. Riding a trend

Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow


0 Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -66%
Trading close to highs
Dist 52W High is 0.0%
Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -154 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -11002%
1 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Biopharmaceutical R&D, Targeted Therapies, Show more.
  Expensive valuation multiples
P/SPrice/Sales ratio is 989x
2   Stock price has recently run up significantly
6M Rtn6 month market price return is 543%, 12M Rtn12 month market price return is 470%
3   Weak revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is -19%
4   Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -10242%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -10246%
5   Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -15%
6   High stock price volatility
Vol 12M is 120%
0 Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -66%
1 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Biopharmaceutical R&D, Targeted Therapies, Show more.
2 Trading close to highs
Dist 52W High is 0.0%
3 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -154 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -11002%
4 Expensive valuation multiples
P/SPrice/Sales ratio is 989x
5 Stock price has recently run up significantly
6M Rtn6 month market price return is 543%, 12M Rtn12 month market price return is 470%
6 Weak revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is -19%
7 Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -10242%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -10246%
8 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -15%
9 High stock price volatility
Vol 12M is 120%

Valuation, Metrics & Events

INBX Stock


Why The Stock Moved


Qualitative Assessment

AI Generated Analysis | Feedback



1. Positive Topline Results for Ozekibart (INBRX-109) in Chondrosarcoma: On October 23, 2025, Inhibrx Biosciences announced positive topline results from its registrational trial of Ozekibart (INBRX-109) in chondrosarcoma. The trial met its primary endpoint, demonstrating a statistically significant and clinically meaningful improvement in median progression-free survival compared to placebo.

2. Confirmation of Ozekibart's Efficacy and Safety Profile: The positive results for Ozekibart were consistent across all pre-specified subgroups, showing improved disease control and quality of life for patients. The company also highlighted a manageable safety profile for Ozekibart after mitigation measures.

Show more

Stock Movement Drivers

Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
INBX Return-----468%468%
Peers Return2%-1%6%8%-0%3%18%
S&P 500 Return16%27%-19%24%23%17%112%

Monthly Win Rates [3]
INBX Win Rate----71%70% 
Peers Win Rate13%8%13%12%10%90% 
S&P 500 Win Rate58%75%42%67%75%70% 

Max Drawdowns [4]
INBX Max Drawdown------30% 
Peers Max Drawdown-2%-5%0%-0%-1%-2% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: VRTX, AIXC, ALPS, BBOT, EVMN.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 12/5/2025 (YTD)

How Low Can It Go

INBX has limited trading history. Below is the Health Care sector ETF (XLV) in its place.

Unique KeyEventXLVS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-16.1%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven19.1%34.1%
2022 Inflation ShockTime to BreakevenTime to Breakeven599 days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-28.8%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven40.4%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven116 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-15.8%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven18.8%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven326 days120 days
2008 Global Financial Crisis2008 Global Financial Crisis  
2008 Global Financial Crisis% Loss% Loss-40.6%-56.8%
2008 Global Financial Crisis% Gain to Breakeven% Gain to Breakeven68.3%131.3%
2008 Global Financial CrisisTime to BreakevenTime to Breakeven1100 days1480 days

Compare to


In The Past

SPDR Select Sector Fund's stock fell -16.1% during the 2022 Inflation Shock from a high on 4/8/2022. A -16.1% loss requires a 19.1% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth over time.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Inhibrx Biosciences (INBX)

Better Bets than Inhibrx Biosciences (INBX)

Trade Ideas

Select past ideas related to INBX. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
9.8%9.8%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-8.8%-8.8%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
2.5%2.5%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
12.5%12.5%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
10.1%10.1%-5.1%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
9.8%9.8%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-8.8%-8.8%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
2.5%2.5%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
12.5%12.5%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
10.1%10.1%-5.1%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for Inhibrx Biosciences

Peers to compare with:

Financials

INBXVRTXAIXCALPSBBOTEVMNMedian
NameInhibrx .Vertex P.AIxCryptoALPS BridgeBi.Evommune  
Mkt Price89.47455.482.501.2113.6921.9017.79
Mkt Cap1.4116.4--0.6-1.4
Rev LTM111,7230-0101
Op Inc LTM-154-92-7--124-70-92
FCF LTM-1433,337-7--87-64-64
FCF 3Y Avg-2,064-8---1,028
CFO LTM-1433,718-7--87-64-64
CFO 3Y Avg-2,419-8---1,205

Growth & Margins

INBXVRTXAIXCALPSBBOTEVMNMedian
NameInhibrx .Vertex P.AIxCryptoALPS BridgeBi.Evommune  
Rev Chg LTM-19.3%10.3%-----4.5%
Rev Chg 3Y Avg-10.5%----10.5%
Rev Chg Q-11.0%----11.0%
QoQ Delta Rev Chg LTM0.0%2.7%----1.3%
Op Mgn LTM-11,002.1%-0.8%----700.7%-700.7%
Op Mgn 3Y Avg-26.2%----26.2%
QoQ Delta Op Mgn LTM927.5%1.0%----464.2%
CFO/Rev LTM-10,242.3%31.7%----635.6%-635.6%
CFO/Rev 3Y Avg-23.1%----23.1%
FCF/Rev LTM-10,245.6%28.5%----636.5%-636.5%
FCF/Rev 3Y Avg-19.8%----19.8%

Valuation

INBXVRTXAIXCALPSBBOTEVMNMedian
NameInhibrx .Vertex P.AIxCryptoALPS BridgeBi.Evommune  
Mkt Cap1.4116.4--0.6-1.4
P/S989.28.5----498.8
P/EBIT-9.522.4---4.8--4.8
P/E-8.927.2---5.2--5.2
P/CFO-9.726.9---6.9--6.9
Total Yield-11.2%3.7%---19.3%--11.2%
Dividend Yield0.0%0.0%--0.0%-0.0%
FCF Yield 3Y Avg-2.3%----2.3%
D/E0.10.0--0.0-0.0
Net D/E-0.0-0.0---0.8--0.0

Returns

INBXVRTXAIXCALPSBBOTEVMNMedian
NameInhibrx .Vertex P.AIxCryptoALPS BridgeBi.Evommune  
1M Rtn10.9%11.2%-65.7%12.7%19.0%12.7%
3M Rtn217.5%15.0%--38.3%-38.3%
6M Rtn542.7%1.1%----271.9%
12M Rtn469.9%-1.4%----234.2%
3Y Rtn-41.8%----41.8%
1M Excs Rtn7.7%8.1%-36.8%9.3%-8.7%
3M Excs Rtn201.7%9.5%--18.6%-18.6%
6M Excs Rtn528.2%-13.4%----257.4%
12M Excs Rtn482.9%-13.9%----234.5%
3Y Excs Rtn--24.4%-----24.4%

Financials

Price Behavior

Short Interest

Short Interest: As Of Date11142025
Short Interest: Shares Quantity1,136,139
Short Interest: % Change Since 1031202510.7%
Average Daily Volume346,540
Days-to-Cover Short Interest3.28
Basic Shares Quantity15,478,000
Short % of Basic Shares7.3%

Earnings Returns History

Expand for More

 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
11/14/2025-2.2%6.1% 
8/13/20251.6%3.6%16.8%
3/17/20250.4%5.6%-15.4%
11/14/2024-3.5%-2.4%1.6%
8/13/2024-0.1%14.2%33.5%
SUMMARY STATS   
# Positive243
# Negative312
Median Positive1.0%5.8%16.8%
Median Negative-2.2%-2.4%-15.4%
Max Positive1.6%14.2%33.5%
Max Negative-3.5%-2.4%-15.4%

SEC Filings

Expand for More

Report DateFiling DateFiling
93020251114202510-Q 9/30/2025
6302025813202510-Q 6/30/2025
3312025514202510-Q 3/31/2025
12312024317202510-K 12/31/2024
93020241114202410-Q 9/30/2024
6302024813202410-Q 6/30/2024
3312024515202410-12B/A 3/31/2024
12312023508202410-12B/A 12/31/2023

Insider Activity

Expand for More

 OwnerTitleFiling DateActionPriceSharesTransacted
Value
Value of
Held Shares
Form
0VIKING GLOBAL INVESTORS LP 10092025Sell32.25308,6439,953,73740,887,292Form