Tearsheet

Hologic (HOLX)


Market Price (11/10/2025): $73.76 | Market Cap: $16.7 Bil
Sector: Health Care | Industry: Health Care Equipment

Hologic (HOLX)


Market Price (11/10/2025): $73.76
Market Cap: $16.7 Bil
Sector: Health Care
Industry: Health Care Equipment

Investment Highlights Why It Matters Which of these 2 stories sounds closer for this stock?

1. Generates cash flow

The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.

2. Riding a trend

Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow


0 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 28%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 24%
Weak multi-year price returns
2Y Excs Rtn is -31%, 3Y Excs Rtn is -59%
Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 21x, P/EPrice/Earnings or Price/(Net Income) is 30x
1 Attractive yield
FCF Yield is 5.8%
  Weak revenue growth
Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -8.5%, Rev Chg QQuarterly Revenue Change % is -1.2%
2 Low stock price volatility
Vol 12M is 30%
  
0 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 28%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 24%
1 Attractive yield
FCF Yield is 5.8%
2 Low stock price volatility
Vol 12M is 30%
3 Weak multi-year price returns
2Y Excs Rtn is -31%, 3Y Excs Rtn is -59%
4 Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 21x, P/EPrice/Earnings or Price/(Net Income) is 30x
5 Weak revenue growth
Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -8.5%, Rev Chg QQuarterly Revenue Change % is -1.2%

Market Valuation & Key Metrics

HOLX Stock


Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
HOLX Return39%5%-2%-4%1%3%42%
Peers Return10%11%-8%-18%-11%-9%-24%
S&P 500 Return16%27%-19%24%23%14%108%

Monthly Win Rates [3]
HOLX Win Rate75%58%50%50%42%70% 
Peers Win Rate38%35%38%40%35%53% 
S&P 500 Win Rate58%75%42%67%75%70% 

Max Drawdowns [4]
HOLX Max Drawdown-44%-17%-20%-13%-1%-27% 
Peers Max Drawdown-17%-5%-16%-29%-22%-17% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: RMD, COO, HSIC, CUPR, MHUA. See HOLX Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 11/7/2025 (YTD)

How Low Can It Go

Unique KeyEventHOLXS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-27.7%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven38.3%34.1%
2022 Inflation ShockTime to BreakevenTime to Breakeven604 days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-46.2%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven86.0%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven88 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-22.8%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven29.5%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven494 days120 days
2008 Global Financial Crisis2008 Global Financial Crisis  
2008 Global Financial Crisis% Loss% Loss-73.7%-56.8%
2008 Global Financial Crisis% Gain to Breakeven% Gain to Breakeven279.6%131.3%
2008 Global Financial CrisisTime to BreakevenTime to Breakeven367 days1480 days

Compare to RMD, COO, HSIC, CUPR, MHUA


In The Past

Hologic's stock fell -27.7% during the 2022 Inflation Shock from a high on 2/4/2021. A -27.7% loss requires a 38.3% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth over time.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Hologic (HOLX)

Better Bets than Hologic (HOLX)

Latest Trefis Analyses

Trade Ideas

Select past ideas related to HOLX. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
GDRX_10312025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG10312025GDRXGoodRxDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
-7.7%-7.7%-7.7%
DXCM_10312025_Monopoly_xInd_xCD_Getting_Cheaper10312025DXCMDexComMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-5.5%-5.5%-5.5%
ACHC_10242025_Dip_Buyer_ValueBuy10242025ACHCAcadia HealthcareDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
-16.6%-16.6%-16.6%
PBH_10102025_Dip_Buyer_ValueBuy10102025PBHPrestige Consumer HealthcareDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
-1.7%-1.7%-1.9%
REGN_10032025_Dip_Buyer_ValueBuy10032025REGNRegeneron PharmaceuticalsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
9.6%9.6%-7.0%
HOLX_4302025_Dip_Buyer_ValueBuy04302025HOLXHologicDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
27.1%27.3%-9.4%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
GDRX_10312025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG10312025GDRXGoodRxDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
-7.7%-7.7%-7.7%
DXCM_10312025_Monopoly_xInd_xCD_Getting_Cheaper10312025DXCMDexComMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-5.5%-5.5%-5.5%
ACHC_10242025_Dip_Buyer_ValueBuy10242025ACHCAcadia HealthcareDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
-16.6%-16.6%-16.6%
PBH_10102025_Dip_Buyer_ValueBuy10102025PBHPrestige Consumer HealthcareDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
-1.7%-1.7%-1.9%
REGN_10032025_Dip_Buyer_ValueBuy10032025REGNRegeneron PharmaceuticalsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
9.6%9.6%-7.0%
HOLX_4302025_Dip_Buyer_ValueBuy04302025HOLXHologicDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
27.1%27.3%-9.4%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for Hologic

Financials

HOLXRMDCOOHSICCUPRMHUAMedian
NameHologic ResMed Cooper C.Henry Sc.Cuprina Meihua I. 
Mkt Price74.10251.4970.1071.900.830.2371.00
Mkt Cap16.736.814.08.6--15.4
Rev LTM4,0265,2574,04612,938--4,652
Op Inc LTM7581,762741764--761
FCF LTM9701,757412356--691
FCF 3Y Avg9201,299274455--687
CFO LTM1,1321,883816535--974
CFO 3Y Avg1,0651,420665644--865

Growth & Margins

HOLXRMDCOOHSICCUPRMHUAMedian
NameHologic ResMed Cooper C.Henry Sc.Cuprina Meihua I. 
Rev Chg LTM1.7%9.4%6.4%3.5%--4.9%
Rev Chg 3Y Avg-8.5%13.3%7.9%0.9%--4.4%
Rev Chg Q-1.2%9.1%5.7%5.2%--5.5%
QoQ Delta Rev Chg LTM-0.3%2.2%1.4%1.3%--1.4%
Op Mgn LTM18.8%33.5%18.3%5.9%--18.6%
Op Mgn 3Y Avg19.6%30.3%16.5%5.7%--18.0%
QoQ Delta Op Mgn LTM-4.4%0.7%-0.7%-0.1%---0.4%
CFO/Rev LTM28.1%35.8%20.2%4.1%--24.1%
CFO/Rev 3Y Avg26.5%29.1%17.5%5.1%--22.0%
FCF/Rev LTM24.1%33.4%10.2%2.8%--17.1%
FCF/Rev 3Y Avg22.9%26.5%7.2%3.6%--15.0%

Valuation

HOLXRMDCOOHSICCUPRMHUAMedian
NameHologic ResMed Cooper C.Henry Sc.Cuprina Meihua I. 
Mkt Cap16.736.814.08.6--15.4
P/S4.27.03.50.7--3.8
P/EBIT20.820.919.412.9--20.1
P/E30.125.634.322.1--27.8
P/CFO14.819.517.116.2--16.6
Total Yield3.3%4.8%2.9%4.5%--3.9%
Dividend Yield0.0%0.9%0.0%0.0%--0.0%
FCF Yield 3Y Avg5.4%3.9%1.7%5.0%--4.5%
D/E0.20.00.20.4--0.2
Net D/E0.1-0.00.20.4--0.1

Returns

HOLXRMDCOOHSICCUPRMHUAMedian
NameHologic ResMed Cooper C.Henry Sc.Cuprina Meihua I. 
1M Rtn9.4%-7.5%2.5%13.8%-13.1%-42.2%-2.5%
3M Rtn8.9%-11.4%-0.3%9.0%-89.8%-45.7%-5.8%
6M Rtn30.6%2.8%-14.8%4.7%-82.8%-27.2%-6.0%
12M Rtn-5.9%0.3%-32.4%5.7%--57.3%-5.9%
3Y Rtn-1.2%14.6%-7.1%-7.0%--97.6%-7.0%
1M Excs Rtn-------
3M Excs Rtn0.6%-20.0%-9.5%0.3%-98.4%-53.4%-14.8%
6M Excs Rtn27.2%-0.5%-18.2%1.4%-86.2%-30.6%-9.4%
12M Excs Rtn-18.8%-9.6%-46.2%-8.6%--77.5%-18.8%
3Y Excs Rtn-58.5%-39.7%-54.6%-55.1%--155.7%-55.1%

Financials

Price Behavior

Short Interest

Short Interest: As Of Date10152025
Short Interest: Shares Quantity3,501,521
Short Interest: % Change Since 930202513.0%
Average Daily Volume1,426,870
Days-to-Cover Short Interest2.45
Basic Shares Quantity225,774,000
Short % of Basic Shares1.6%

Earnings Returns History

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 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
11/3/20250.1%  
7/30/20252.8%2.9%2.5%
5/1/2025-5.4%-1.9%8.3%
1/13/2025-2.0%-2.7%-10.1%
11/4/2024-5.9%-5.2%-8.2%
7/29/20243.6%3.4%0.1%
5/2/20240.8%-0.2%-1.8%
2/1/2024-2.6%-1.3%0.3%
...
SUMMARY STATS   
# Positive141113
# Negative101311
Median Positive3.2%6.3%5.3%
Median Negative-3.1%-2.4%-6.2%
Max Positive9.3%14.6%12.3%
Max Negative-8.5%-9.5%-13.8%

SEC Filings

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Report DateFiling DateFiling
6302025731202510-Q 6/28/2025
3312025502202510-Q 3/29/2025
12312024206202510-Q 12/28/2024
93020241127202410-K 9/28/2024
6302024730202410-Q 6/29/2024
3312024503202410-Q 3/30/2024
12312023202202410-Q 12/30/2023
93020231121202310-K 9/30/2023
6302023801202310-Q 7/1/2023
3312023502202310-Q 4/1/2023
12312022201202310-Q 12/31/2022
93020221115202210-K 9/24/2022
6302022727202210-Q 6/25/2022
3312022427202210-Q 3/26/2022
12312021202202210-Q 12/25/2021
93020211116202110-K 9/25/2021

Insider Activity

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