Market Movers | Winners: INDP, BBNX, SWKS | Losers: SWMR, ENVA, ALHC
A day of modest index declines hid significant persistence in the market’s biggest winners and losers.
Swarmer (SWMR) fell 28.4% in a session that saw major indexes post smaller declines. The S&P 500 returned -0.4% while the Dow Jones Industrial Average and the Nasdaq-100 each returned -0.6%. This raises a critical question for any disciplined observer: when is a dramatic one-day move part of a larger trend, and when is it just noise? The day’s largest percentage changes are a starting point.

Tuesday’s Market Winners
The 10 US-listed stocks in the Trefis coverage universe with the highest returns on the last trading day:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | INDP | Indaptus Therapeutics | 15.9% | 25.1% |
| 2 | BBNX | Beta Bionics | 14.9% | -36.9% |
| 3 | SWKS | Skyworks Solutions | 13.6% | 44.9% |
| 4 | FTRE | Fortrea | 13.3% | 14.4% |
| 5 | SDGR | Schrodinger | 12.0% | 30.0% |
| 6 | TEM | Tempus AI | 10.7% | 16.6% |
| 7 | CAI | Caris Life Sciences | 9.4% | 5.6% |
| 8 | QRVO | Qorvo | 9.3% | 39.7% |
| 9 | RVTY | Revvity | 9.1% | 45.2% |
| 10 | RIG | Transocean | 9.0% | 43.8% |
Tuesday’s Market Losers
And the 10 US-listed stocks in the Trefis coverage universe with the lowest returns:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | SWMR | Swarmer | -28.4% | n/a |
| 2 | ENVA | Enova International | -23.4% | 10.4% |
| 3 | ALHC | Alignment Healthcare | -19.9% | -47.5% |
| 4 | SION | Sionna Therapeutics | -16.7% | -83.3% |
| 5 | CTMX | CytomX Therapeutics | -15.9% | -36.9% |
| 6 | KRUS | Kura Sushi USA | -14.0% | -32.2% |
| 7 | CYPH | Cypherpunk Technologies | -14.0% | 91.4% |
| 8 | EYPT | EyePoint | -13.9% | -80.0% |
| 9 | DMRA | Damora Therapeutics | -12.8% | 7.6% |
| 10 | FWDI | Forward Industries | -12.5% | -8.0% |
Tuesday’s biggest moves are not one-day events.
The theme across time horizons is persistence. Indaptus Therapeutics (INDP), the day’s top gainer, also appears on the one-month winners list with a return of +240.2%. Its strength is not a one-day event; excluding yesterday, the stock still gained +193.5% over the other sessions. Swarmer (SWMR) shows the same pattern in reverse. It appears on both the one-day and one-month losers lists, with a one-month return of -44.6%. Its weakness has been building, as it still lost 22.7% in the month’s other sessions.
Movers Over The Last Week
Widening the window to five trading days, these are the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | INDP | Indaptus Therapeutics | 96.8% | 25.1% |
| 2 | ACVA | ACV Auctions | 48.4% | 30.0% |
| 3 | IRD | Opus Genetics | 34.1% | 189.6% |
| 4 | MYGN | Myriad Genetics | 22.0% | -36.9% |
| 5 | NTSK | Netskope | 21.7% | -0.4% |
| 6 | S | SentinelOne | 20.8% | 56.5% |
| 7 | INSP | Inspire Medical Systems | 20.1% | -19.1% |
| 8 | ZS | Zscaler | 19.7% | -13.8% |
| 9 | SWKS | Skyworks Solutions | 19.4% | 44.9% |
| 10 | RPD | Rapid7 | 19.1% | -18.0% |
Losers
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | TTAN | ServiceTitan | -28.2% | -45.0% |
| 2 | BRUN | Boost Run | -27.9% | n/a |
| 3 | SWMR | Swarmer | -27.7% | n/a |
| 4 | ALM | Almonty Industries | -26.6% | 59.4% |
| 5 | CTMX | CytomX Therapeutics | -26.3% | -36.9% |
| 6 | ASMB | Assembly Biosciences | -26.0% | -23.2% |
| 7 | OCGN | Ocugen | -25.3% | -26.4% |
| 8 | ASPI | ASP Isotopes | -25.1% | -40.9% |
| 9 | ORBS | Eightco | -24.6% | -50.3% |
| 10 | SMR | NuScale Power | -24.6% | -40.5% |
Movers Over The Last Month
And over the last 21 trading days, the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | CYPH | Cypherpunk Technologies | 244.7% | 91.4% |
| 2 | INDP | Indaptus Therapeutics | 240.2% | 25.1% |
| 3 | MRNA | Moderna | 127.1% | 387.5% |
| 4 | ARCT | Arcturus Therapeutics | 92.5% | 158.4% |
| 5 | PURR | Hyperliquid Strategies | 67.7% | 214.6% |
| 6 | IRD | Opus Genetics | 61.2% | 189.6% |
| 7 | AMLX | Amylyx Pharmaceuticals | 53.3% | 174.4% |
| 8 | CVI | CVR Energy | 48.0% | 106.3% |
| 9 | FWDI | Forward Industries | 42.7% | -8.0% |
| 10 | TTRX | Turn Therapeutics | 40.6% | 241.6% |
Losers
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | EYPT | EyePoint | -75.2% | -80.0% |
| 2 | ALMS | Alumis | -66.8% | -13.9% |
| 3 | RARE | Ultragenyx Pharmaceutical | -50.7% | -43.2% |
| 4 | SWMR | Swarmer | -44.6% | n/a |
| 5 | ALOY | REalloys | -42.5% | n/a |
| 6 | CRDO | Credo Technology | -42.1% | 4.5% |
| 7 | BRUN | Boost Run | -40.8% | n/a |
| 8 | KRMN | Karman | -39.6% | -48.8% |
| 9 | AEHR | Aehr Test Systems | -39.1% | 304.1% |
| 10 | AEVA | Aeva Technologies | -39.0% | 6.9% |
A large price change is a starting point for research.
The tables of market movers shown earlier are best used as a map of attention, not a set of instructions. A stock appearing on these lists has experienced a significant price change, drawing investor focus. But a large move is simply new information. The disciplined follow-up is always the same: to investigate the business behind the ticker and understand what has, or has not, changed in its fundamentals.
Either side of these lists can be a lead worth following, with the same follow-up question: does the business back the move? For the winners, our Guidance Momentum screen tracks which companies raised their own forward numbers. For the losers, our Buy the Dip screen flags which marked-down names still have the fundamentals to recover.
Volatility Is The Cost Of Owning Stocks. Concentration Makes It A Bill
Every name on these lists made a move big enough to notice. A diversified holder reads that as noise; a concentrated holder feels it as real money. The difference is not the stock, it is the portfolio around it.
Building that portfolio is what the Trefis High Quality (HQ) Portfolio does: roughly 30 businesses with the cash generation and balance-sheet strength to absorb bad days, selected and rebalanced by rules. It has a track record of outpacing a benchmark that combines the S&P 500, the S&P MidCap 400, and the Russell 2000. Let the movers list remind you why diversification exists.