Market Movers | Winners: TTRX, ORBS, NUAI | Losers: DYN, SGML, XFOR
A day of sharp individual moves raises the question of which gains have staying power.
The S&P 500 fell 0.6% on the day, with the Dow Jones Industrial Average down 1.2%. Against that backdrop, Turn Therapeutics (TTRX) posted a gain of +29.2%.
The real question for any investor scanning a list of extremes is whether a move is a one-off event or part of a larger trend. Today’s lists offer a clear example of both.
Tuesday’s Market Winners
The 10 stocks with the highest returns on the last trading day:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | TTRX | Turn Therapeutics | 29.2% | 221.3% |
| 2 | ORBS | Eightco | 26.2% | -34.1% |
| 3 | NUAI | New Era Energy & Digital | 22.0% | 125.3% |
| 4 | FCEL | FuelCell Energy | 18.8% | 143.0% |
| 5 | ROIV | Roivant Sciences | 18.8% | 91.2% |
| 6 | SEI | Solaris Energy Infrastructure | 16.3% | 39.7% |
| 7 | TMS | Teamshares | 16.0% | n/a |
| 8 | SATL | Satellogic | 15.3% | 186.1% |
| 9 | SMR | NuScale Power | 15.3% | -21.1% |
| 10 | ALTI | AlTi Global | 14.0% | -26.3% |
Tuesday’s Market Losers
And the 10 stocks with the lowest returns:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | DYN | Dyne Therapeutics | -16.4% | 3.8% |
| 2 | SGML | Sigma Lithium | -15.8% | -20.9% |
| 3 | XFOR | X4 Pharmaceuticals | -13.2% | -12.4% |
| 4 | CNXC | Concentrix | -12.1% | -29.3% |
| 5 | HWM | Howmet Aerospace | -10.7% | 13.1% |
| 6 | SANA | Sana Biotechnology | -10.4% | -15.2% |
| 7 | MEI | Methode Electronics | -10.4% | 115.4% |
| 8 | AMGN | Amgen | -10.1% | 22.6% |
| 9 | APPN | Appian | -9.9% | -2.4% |
| 10 | ALIT | Alight | -9.9% | -65.5% |
Some moves show clear persistence across time horizons.
Eightco (ORBS) appears on both the one-day and one-month winners lists. Its one-month return is +65.4%, and its strength is not a one-day event. The stock still gained +31.1% over the other sessions in the period, excluding today’s move.
Movers Over The Last Week
Widening the window to five trading days, these are the strongest and weakest Market names:
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | ORBS | Eightco | 48.9% | -34.1% |
| 2 | MNTK | Montauk Renewables | 45.3% | 49.7% |
| 3 | CYPH | Cypherpunk Technologies | 44.1% | 126.7% |
| 4 | NUAI | New Era Energy & Digital | 39.1% | 125.3% |
| 5 | BE | Bloom Energy | 34.4% | 219.0% |
| 6 | EOSE | Eos Energy Enterprises | 33.5% | -62.5% |
| 7 | TTRX | Turn Therapeutics | 31.9% | 221.3% |
| 8 | EPRX | Eupraxia Pharmaceuticals | 27.7% | 9.3% |
| 9 | NRGV | Energy Vault | 27.1% | -6.3% |
| 10 | SMMT | Summit Therapeutics | 26.9% | -1.2% |
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | ALMS | Alumis | -51.5% | 8.4% |
| 2 | RARE | Ultragenyx Pharmaceutical | -41.0% | -35.3% |
| 3 | CXM | Sprinklr | -32.4% | -28.7% |
| 4 | GWRE | Guidewire Software | -26.9% | -25.5% |
| 5 | CRDO | Credo Technology | -25.8% | 16.6% |
| 6 | PATH | UiPath | -25.0% | -14.5% |
| 7 | MEI | Methode Electronics | -22.9% | 115.4% |
| 8 | RPD | Rapid7 | -22.3% | -31.2% |
| 9 | MDB | MongoDB | -21.5% | -15.2% |
| 10 | DYN | Dyne Therapeutics | -20.1% | 3.8% |
Movers Over The Last Month
And over the last 21 trading days:
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | CYPH | Cypherpunk Technologies | 281.9% | 126.7% |
| 2 | MRNA | Moderna | 137.2% | 375.9% |
| 3 | CAPR | Capricor Therapeutics | 121.5% | -68.6% |
| 4 | ARCT | Arcturus Therapeutics | 110.9% | 155.0% |
| 5 | QMCO | Quantum | 103.2% | 279.2% |
| 6 | PURR | Hyperliquid Strategies | 75.2% | 235.1% |
| 7 | HTFL | HeartFlow | 65.7% | 63.8% |
| 8 | ORBS | Eightco | 65.4% | -34.1% |
| 9 | ABCL | AbCellera Biologics | 65.1% | 234.5% |
| 10 | ARX | Accelerant | 59.2% | 21.3% |
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | SION | Sionna Therapeutics | -85.7% | -82.3% |
| 2 | EYPT | EyePoint | -67.2% | -75.0% |
| 3 | ALMS | Alumis | -61.7% | 8.4% |
| 4 | KLC | KinderCare Learning Companies | -50.1% | -40.3% |
| 5 | RARE | Ultragenyx Pharmaceutical | -42.6% | -35.3% |
| 6 | AADX | Applied Aerospace & Defense | -42.5% | n/a |
| 7 | CDNL | Cardinal Infrastructure | -40.3% | 58.1% |
| 8 | LINC | Lincoln Educational Services | -39.5% | 2.7% |
| 9 | AEVA | Aeva Technologies | -39.0% | 22.4% |
| 10 | DKS | Dick’s Sporting Goods | -36.6% | -32.3% |
What is the right way to use these lists?
A large price change is information about attention and risk, never an instruction to act. The names in the tables earlier are starting points for research, not conclusions.
The disciplined follow-up is to investigate the underlying business. A stock price is not the company, and a one-day, one-week, or even one-month return reveals little about its long-term prospects.
Either side of these lists can be a lead worth following, with the same follow-up question: does the business back the move? For the winners, our Guidance Momentum screen tracks which companies raised their own forward numbers. For the losers, our Buy the Dip screen flags which marked-down names still have the fundamentals to recover.
The Tape Rewards Attention. It Punishes Reaction
Big daily moves pull hard at both greed and fear, and acting on either, day after day, is how most portfolios end up trailing the index they were trying to beat.
The Trefis High Quality (HQ) Portfolio is built for the opposite reflex: about 30 quality businesses screened for the fundamentals that survive volatile stretches, held with rules instead of reactions. It has a track record of outpacing a benchmark that combines the three major indices – the S&P 500, S&P Mid-cap, and Russell 2000. Read the movers daily; trade them rarely.