Between Gilead Sciences and Regeneron Pharmaceuticals, Which Stock Looks Set to Break Out?

REGN: Regeneron Pharmaceuticals logo
REGN
Regeneron Pharmaceuticals

Regeneron Pharmaceuticals surged 15% during the past Month. You may be tempted to buy more, or may want to reduce your exposure. But there is an entirely different perspective you might be missing. Is there a better alternative? Turns out, its peer Gilead Sciences gives you more. Gilead Sciences (GILD) stock offers superior revenue growth across key periods, better profitability, and relatively lower valuation vs Regeneron Pharmaceuticals (REGN) stock, suggesting you may be better off investing in GILD

  • GILD’s quarterly revenue growth was 3.0%, vs. REGN’s 0.9%.
  • In addition, its Last 3-Year Average revenue growth came in at 2.3%, ahead of REGN’s 1.4%.
  • GILD leads on profitability over both periods – LTM margin of 38.3% and 3-year average of 39.2%.

These differences become even clearer when you look at the financials side by side. The table highlights how REGN’s fundamentals stack up against those of GILD on growth, margins, momentum, and valuation multiples.

Valuation & Performance Overview

  REGN GILD Preferred
     
Valuation      
P/EBIT Ratio 21.7 13.5 GILD
     
Revenue Growth      
Last Quarter 0.9% 3.0% GILD
Last 12 Months 2.9% 2.8% REGN
Last 3 Year Average 1.4% 2.3% GILD
     
Operating Margins      
Last 12 Months 26.7% 38.3% GILD
Last 3 Year Average 30.0% 39.2% GILD
     
Momentum      
Last 3 Year Return 17.7% 58.1% GILD

Note: For “Last 3 Year Return” metric, preferred stock is one with higher returns unless the returns are too high (>300%) which creates risk of sell off.
See more revenue details: REGN Revenue Comparison | GILD Revenue Comparison
See more margin details: REGN Operating Income Comparison | GILD Operating Income Comparison

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See detailed fundamentals on Buy or Sell GILD Stock and Buy or Sell REGN Stock. Below we compare market return and related metrics across years.

Historical Market Performance

  2021 2022 2023 2024 2025 2026 Total [1] Avg Best
Returns
REGN Return 31% 14% 22% -19% 9% 4% 67%    
GILD Return 30% 24% -2% 19% 37% -2% 151%   <===
S&P 500 Return 27% -19% 24% 23% 16% 1% 84%    
Monthly Win Rates [3]
REGN Win Rate 67% 50% 58% 50% 50% 100%   62%  
GILD Win Rate 58% 33% 42% 67% 67% 0%   44%  
S&P 500 Win Rate 75% 42% 67% 75% 67% 100%   71% <===
Max Drawdowns [4]
REGN Max Drawdown -8% -13% -6% -20% -32% -1%   -13%  
GILD Max Drawdown 0% -20% -12% -21% -3% -4%   -10%  
S&P 500 Max Drawdown -1% -25% -1% -2% -15% 0%   -7% <===

[1] Cumulative total returns since the beginning of 2021
[2] 2026 data is for the year up to 1/9/2026 (YTD)
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year

No matter how good the numbers, stock investment is never a smooth ride. There is a risk you must factor in. Read REGN Dip Buyer Analyses to see how the stock has fallen and recovered in the past.

Still not sure about REGN or GILD? Consider portfolio approach.

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