How Does Eli Lilly Stock Stack Up Against Its Peers?

LLY: Eli Lilly logo
LLY
Eli Lilly

Eli Lilly’s stock has underperformed some key peers over the past year, yet its significant growth in areas like GLP-1 therapies remains notable. A closer look reveals superior profitability and robust revenue acceleration, fueled by its strong pipeline and market leadership in key therapeutic areas. However, a premium valuation and lower free cash flow generation suggest high growth expectations and substantial investment in future drivers, balanced against intensifying competitive and pricing pressures within the pharmaceutical sector.

  • LLY’s 45.6% operating margin, highest among peers, reflects robust GLP-1 drug demand, enabling strong pricing power and an efficient product mix.
  • LLY’s 44.7% revenue growth, outpacing peers, stems from surging GLP-1 drug sales (Mounjaro, Zepbound) driving dominance in diabetes/obesity markets.
  • LLY’s 16.8% stock gain and 43.8 PE, while peers delivered more, signals investors’ high future growth expectations for its blockbuster GLP-1 pipeline.

Here’s how Eli Lilly stacks up across size, valuation, and profitability versus key peers.

  LLY JNJ MRK PFE ABBV AMGN
Market Cap ($ Bil) 903.3 584.1 290.5 152.4 402.4 202.8
Revenue ($ Bil) 65.2 94.2 65.0 62.6 61.2 36.8
PE Ratio 43.8 21.8 15.9 19.6 95.2 26.3
LTM Revenue Growth 44.7% 6.0% 1.3% -1.6% 8.6% 10.0%
LTM Operating Margin 45.6% 27.2% 34.0% 27.8% 32.8% 24.7%
LTM FCF Margin 9.2% 20.5% 19.0% 14.5% 29.1% 22.0%
12M Market Return 16.8% 49.6% 28.4% 7.6% 9.7% 19.7%

For more details on Eli Lilly, read Buy or Sell LLY Stock. Below we compare LLY’s growth, margin, and valuation with peers across years

Trefis: LLY Stock Insights

Revenue Growth Comparison

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  LTM 2025 2024 2023
LLY 44.7% 44.7% 32.0% 19.6%
JNJ 6.0% 6.0% 4.3% 6.5%
MRK 1.3% 1.3% 6.7% 1.4%
PFE -1.6% -1.6% 6.8% -41.1%
ABBV 8.6% 8.6% 3.7% -6.4%
AMGN 10.0% 10.0% 18.6% 7.1%

Operating Margin Comparison

  LTM 2025 2024 2023
LLY 45.6% 45.6% 37.8% 30.3%
JNJ 27.2% 27.2% 23.9% 25.8%
MRK 34.0% 34.0% 31.5% 4.9%
PFE 27.8% 27.8% 23.5% 7.4%
ABBV 32.8% 32.8% 21.1% 24.9%
AMGN 24.7% 24.7% 21.7% 28.0%

PE Ratio Comparison

  LTM 2025 2024 2023
LLY 43.8 46.7 65.7 100.1
JNJ 21.8 18.6 24.8 11.3
MRK 15.9 14.4 14.7 757.8
PFE 19.6 18.2 18.7 76.7
ABBV 95.2 95.6 73.5 56.3
AMGN 26.3 22.8 34.2 22.9

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