Why Johnson & Johnson Stock Jumped 60%?

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JNJ: Johnson & Johnson logo
JNJ
Johnson & Johnson

Over the year from 2/18/2025 to 2/18/2026, Johnson & Johnson (JNJ) rode a powerful 62% stock rally fueled by soaring profits and strong oncology and MedTech sales—despite a notable earnings multiple dip and ongoing legal headwinds. Strategic growth and pipeline wins kept investors hooked.

Below is an analytical breakdown of stock movement into key contributing metrics.

  2182025 2182026 Change
Stock Price ($) 151.6 245.0 61.6%
Total Revenues ($ Mil) 88,821.0 94,193.0 6.0%
Net Income Margin (%) 15.8% 28.5% 79.7%
P/E Multiple 25.9 22.0 -15.2%
Shares Outstanding (Mil) 2,407.0 2,407.7 -0.0%
Cumulative Contribution 61.6%

So what is happening here? A 62% stock surge was driven by a 6% rise in revenue and a sharp 80% boost in net income margin, despite a 15% dip in P/E multiple and nearly flat shares outstanding.

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Here Is Why Johnson & Johnson Stock Moved

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  • Oncology Growth Driver: Full-year 2025 oncology sales grew 21% operationally, with DARZALEX crossing $14 billion in annual revenue, demonstrating a significant growth driver.
  • MedTech Segment Strength: The MedTech segment reported a 6.1% operational sales increase in Q2 2025, with cardiovascular product sales surging, indicating robust commercial execution.
  • Pipeline Acceleration: Received FDA Breakthrough Therapy Designation for RYBREVANT FASPRO for head and neck cancer on 2/18/2026, one of 51 regulatory approvals in 2025.
  • CapEx for Future Growth: Announced a new $1B+ cell therapy manufacturing site on 2/18/2026, part of a plan to increase high-growth asset share of the MedTech portfolio to over 70%.
  • Persistent Legal Risk: Lost a talc trial on 2/13/2026, adding to over 67,000 active lawsuits, creating a direct earnings reserve risk against a guided $21B in 2026 free cash flow.

Current Assesment Of JNJ Stock

The core investment debate is centered around: Can accelerating growth from the innovative pipeline (Oncology, MedTech) fully offset the material revenue erosion from Stelara’s loss of exclusivity and absorb major litigation/regulatory risks?

The prevailing sentiment appears to be neutral. Sentiment is pinned at Neutral. The impressive, accelerating growth in the new portfolio (+) is in a direct tug-of-war with the massive, quantifiable Stelara patent cliff (-) and the unquantifiable talc litigation overhang (-). The company is executing well, but the headwinds are structural.

Bull View Bear View
Strong growth in Darzalex, Carvykti, and Tremfya, plus a deep pipeline, will overwhelm the Stelara headwind, leading to re-accelerated growth and a higher multiple in 2026. The ~50% decline in the ~$10B Stelara franchise, combined with unquantified talc liability and IRA margin pressure, creates an insurmountable drag on growth and sentiment.

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