Insmed Stock Drop Looks Sharp, But How Deep Can It Go?

INSM: Insmed logo
INSM
Insmed

Insmed (INSM) stock is down 14.3% in 21 trading days. The recent slide reflects renewed concerns following the failed CRSsNP trial, but sharp drops like this often raise a tougher question: is the weakness temporary, or a sign of deeper cracks in the story?

Before judging its downturn reslience, let’s look at where Insmed stands today.

  • Size: Insmed is a $38 Bil company with $447 Mil in revenue currently trading at $177.42.
  • Fundamentals: Last 12 month revenue growth of 30.3% and operating margin of -221.5%.
  • Liquidity: Has Debt to Equity ratio of 0.02 and Cash to Assets ratio of 0.71
  • Valuation: Insmed stock is currently trading at P/E multiple of -31.7 and P/EBIT multiple of -34.1
  • Has returned (median) -23.1% within a year following sharp dips since 2010. See INSM Dip Buy Analysis.

These metrics point to a Moderate operational performance, alongside Very High valuation – making the stock Unattractive. For details, see Buy or Sell INSM Stock

That brings us to the key consideration for investors worried about this fall: how resilient is INSM stock if markets turn south? This is where our downturn resilience framework comes in. Suppose INSM stock falls another 20-30% to $124 – can investors comfortably hold on? Turns out, the stock has fared worse than the S&P 500 index during various economic downturns, based on (a) how much the stock fell and, (b) how quickly it recovered. Below, we dive deeper into each such downturn.

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2022 Inflation Shock

  • INSM stock fell 63.3% from a high of $44.30 on 8 February 2021 to $16.26 on 22 March 2023 vs. a peak-to-trough decline of 25.4% for the S&P 500.
  • However, the stock fully recovered to its pre-Crisis peak by 28 May 2024
  • Since then, the stock increased to a high of $211.41 on 1 December 2025 , and currently trades at $177.42

  INSM S&P 500
% Change from Pre-Recession Peak -63.3% -25.4%
Time to Full Recovery 433 days 464 days

 
2020 Covid Pandemic

  • INSM stock fell 59.9% from a high of $33.98 on 5 February 2020 to $13.63 on 23 March 2020 vs. a peak-to-trough decline of 33.9% for the S&P 500.
  • However, the stock fully recovered to its pre-Crisis peak by 16 September 2020

  INSM S&P 500
% Change from Pre-Recession Peak -59.9% -33.9%
Time to Full Recovery 177 days 148 days

 
2018 Correction

  • INSM stock fell 64.8% from a high of $32.99 on 3 January 2018 to $11.60 on 24 December 2018 vs. a peak-to-trough decline of 19.8% for the S&P 500.
  • However, the stock fully recovered to its pre-Crisis peak by 4 February 2020

  INSM S&P 500
% Change from Pre-Recession Peak -64.8% -19.8%
Time to Full Recovery 407 days 120 days

 
2008 Global Financial Crisis

  • INSM stock fell 77.6% from a high of $156.00 on 2 March 2007 to $34.99 on 6 November 2008 vs. a peak-to-trough decline of 56.8% for the S&P 500.
  • However, the stock fully recovered to its pre-Crisis peak by 18 May 2009

  INSM S&P 500
% Change from Pre-Recession Peak -77.6% -56.8%
Time to Full Recovery 193 days 1,480 days

 
Feeling jittery about INSM stock? Consider portfolio approach.

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The Trefis High Quality (HQ) Portfolio, with a collection of 30 stocks, has a track record of comfortably outperforming its benchmark that includes all 3 – the S&P 500, S&P mid-cap, and Russell 2000 indices. Why is that? As a group, HQ Portfolio stocks provided better returns with less risk versus the benchmark index; less of a roller-coaster ride, as evident in HQ Portfolio performance metrics.