How Does Gilead Sciences Stock Stack Up Against Its Peers?

GILD: Gilead Sciences logo
GILD
Gilead Sciences

Gilead Sciences’ stock delivered solid 35% returns over the past year, but how does it truly measure up against pharmaceutical peers like JNJ and MRK, who outperformed with 55% and 37% respectively? A closer look reveals GILD’s leading profitability, boasting a 39.7% operating margin and 32.1% FCF margin, alongside a moderate 21.9x PE ratio. While its 2.4% revenue growth trails some rivals and its 2026 outlook was conservative, potentially limiting upside amidst evolving healthcare demands, the company maintains a robust core business and analyst optimism for long-term growth.

  • GILD’s 39.7% operating margin, highest among peers, stems from its efficient HIV franchise and strong specialty drug pricing.
  • GILD’s 2.4% revenue growth, lagging ABBV, PFE, JNJ, reflects Veklury/cell therapy declines, outpacing MRK/BMY with strong HIV sales.
  • GILD’s 34.9% stock gain and 21.9 PE, below MRK/JNJ’s stronger returns, reflect investor pipeline caution versus diverse peer growth.

Here’s how Gilead Sciences stacks up across size, valuation, and profitability versus key peers.

  GILD ABBV MRK BMY PFE JNJ
Market Cap ($ Bil) 186.2 414.4 301.2 126.8 155.0 598.5
Revenue ($ Bil) 29.4 61.2 65.0 48.2 62.8 94.2
PE Ratio 21.9 98.1 16.5 18.0 15.8 22.3
LTM Revenue Growth 2.4% 8.6% 1.3% -0.2% 3.9% 6.0%
LTM Operating Margin 39.7% 32.8% 34.0% 28.5% 24.6% 27.2%
LTM FCF Margin 32.1% 29.1% 19.0% 26.7% 16.5% 20.5%
12M Market Return 34.9% 15.8% 36.6% 9.8% 10.6% 54.8%

For more details on Gilead Sciences, read Buy or Sell GILD Stock. Below we compare GILD’s growth, margin, and valuation with peers across years

Trefis: GILD Stock Insights

Revenue Growth Comparison

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  LTM 2025 2024 2023 2022
GILD 2.4% 2.4% 6.0% -0.6%  
ABBV 8.6% 8.6% 3.7% -6.4%  
MRK 1.3% 1.3% 6.7% 1.4%  
BMY -0.2% -0.2% 7.3% -2.5%  
PFE 3.9% 6.8% -41.1% 24.5%
JNJ 6.0% 6.0% 4.3% 6.5%  

Operating Margin Comparison

  LTM 2025 2024 2023 2022
GILD 39.7% 39.7% 36.9% 32.6%  
ABBV 32.8% 32.8% 21.1% 24.9%  
MRK 34.0% 34.0% 31.5% 4.9%  
BMY 28.5% 28.5% 12.2% 18.2%  
PFE 24.6% 23.3% 7.1% 36.7%
JNJ 27.2% 27.2% 23.9% 25.8%  

PE Ratio Comparison

  LTM 2025 2024 2023 2022
GILD 21.9 17.9 240.0 17.8  
ABBV 98.1 95.6 73.5 56.3  
MRK 16.5 14.4 14.7 757.8  
BMY 18.0 15.6 -12.8 13.2  
PFE 15.8 17.6 70.7 5.1
JNJ 22.3 18.6 24.8 11.3  

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