Tearsheet

State Street SPDR S&P Biotech ETF (XBI)

Market Price (5/22/2026): $132.76

State Street SPDR S&P Biotech ETF (XBI)

Market Price (5/22/2026): $132.76

Asset Allocation with XBI

	ETF	1D	1W	1M	YTD
Equity	XBI	0.8%	-1.5%	-3.3%	8.9%
Bond	BND	0.1%	-0.3%	-0.9%	-0.2%
Gold	GLD	-0.1%	-2.4%	-4.2%	5.2%
Commodity	DBC	-0.6%	-1.4%	4.0%	37.3%
Real Estate	VNQ	0.2%	1.4%	2.3%	10.4%
Bitcoin	BTCUSD	0.5%	-4.0%	-0.5%	-11.1%
Cash	GOVT	0.1%	-0.3%	-1.3%	-0.9%

	ETF	Return	Volatility	Sharpe
Equity	XBI	10.5%	29.2%	44.1%
Bond	BND	1.6%	5.2%	-20.4%
Gold	GLD	13.2%	15.0%	68.6%
Commodity	DBC	7.8%	16.7%	37.6%
Real Estate	VNQ	5.4%	17.7%	21.9%
Bitcoin	BTCUSD	67.2%	76.6%	100.9%
Cash	GOVT	0.5%	5.0%	-42.2%

Figures are on an annualized basis, based on monthly return data for the last 10 years

	ETF	Inflation Shock	Covid Pandemic	2018 Correction
Equity	XBI	-25.2%	-27.0%	-32.6%
Bond	BND	-14.2%	-2.2%	1.3%
Gold	GLD	-7.7%	-6.3%	5.0%
Commodity	DBC	20.5%	-23.7%	-17.5%
Real Estate	VNQ	-29.8%	-41.6%	-11.1%
Bitcoin	BTCUSD	-56.0%	-33.5%	-37.4%
Cash	GOVT	-12.4%	4.4%	1.6%

The table shows the return of different asset classes during market crises - specifically during the period where the S&P fell and bottomed

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Price Chart

ETF Price
Price/Gold

Valuation & Yield

	5/22/26	2025	2024	2023	2022	2021
Share Price CYE	$132.78	$121.93	$90.02	$89.12	$82.83	$111.73
Dividend/Share TTM	$0.03	$0.04	$0.13	$0.02	$0.00	$0.04
Valuation [1]
P/S TTM	6.72	6.54	6.91	7.33	6.75	10.73
P/E TTM	49.49	38.98	35.96	77.88	53.99	46.40
Yields TTM
Earnings Yield	2.02%	2.57%	2.78%	1.28%	1.85%	2.16%
Dividend Yield	0.03%	0.03%	0.15%	0.02%	0.00%	0.04%
Total Yield (TY)	2.05%	2.60%	2.93%	1.30%	1.85%	2.19%
Risk Premium [2]
Risk Free Rate (Rf)	4.57%	4.18%	4.58%	3.88%	3.88%	1.52%
Risk Prem. (TY - Rf)	-2.52%	-1.58%	-1.65%	-2.58%	-2.03%	0.67%

[1] P/E uses aggregate method (profitable constituents only); P/S uses all constituents. Ratios reflect current ETF holdings at current weights.
[2] The premium above the risk free rate (US 10Y) offered by the investment. Negative premiums can indicate stretched valuations.

Top 20 Holdings for XBI

Total Weights
Top 5: 8.2% | Top 10: 15.3% | Top 20: 28.1%

Ticker	Holding	Weight
RVMD	Revolution Medicines	1.76%
TVTX	Travere Therapeutics	1.72%
TGTX	TG Therapeutics	1.65%
ALKS	Alkermes	1.55%
ARWR	Arrowhead Pharmaceuticals	1.55%
CYTK	Cytokinetics	1.45%
CELC	Celcuity	1.42%
EXEL	Exelixis	1.40%
NBIX	Neurocrine Biosciences	1.39%
MDGL	Madrigal Pharmaceuticals	1.39%
KRYS	Krystal Biotech	1.38%
TWST	Twist Bioscience	1.34%
PRAX	Praxis Precision Medicines	1.32%
SRRK	Scholar Rock	1.31%
ROIV	Roivant Sciences	1.28%
APGE	Apogee Therapeutics	1.27%
PTCT	PTC Therapeutics	1.26%
IMVT	Immunovant	1.26%
MIRM	Mirum Pharmaceuticals	1.23%
PTGX	Protagonist Therapeutics	1.22%

Performance for XBI Top Holdings

Ticker	Holding	Weight	Mkt Price 5/21	1D Rtn	1M Rtn	YTD Rtn	1Y Rtn	3Y Rtn	5Y Rtn	10Y Rtn
XBI	State Street SPDR S&P Biotech ETF	100.00%	132.78	0.8%	-2.6%	8.9%	67.4%	52.1%	5.0%	144.9%
RVMD	Revolution Medicines	1.76%	153.73	2.3%	3.2%	93.0%	296.8%	476.0%	389.7%
TVTX	Travere Therapeutics	1.72%	44.74	2.9%	15.4%	17.1%	169.5%	164.0%	147.3%	166.3%
TGTX	TG Therapeutics	1.65%	39.24	-1.3%	8.2%	31.6%	14.7%	37.3%	18.2%	405.7%
ALKS	Alkermes	1.55%	36.95	-0.1%	10.2%	32.1%	21.0%	31.5%	79.1%	-7.3%
ARWR	Arrowhead Pharmaceuticals	1.55%	75.54	-2.1%	6.3%	13.8%	393.4%	106.8%	1.8%	1,239.4%
CYTK	Cytokinetics	1.45%	78.06	-0.9%	18.6%	22.9%	149.3%	91.6%	238.7%	908.5%
CELC	Celcuity	1.42%	142.53	1.6%	13.1%	42.9%	1,244.6%	1,244.6%	400.6%
EXEL	Exelixis	1.40%	49.65	-0.5%	8.2%	13.3%	13.6%	151.1%	103.0%	727.5%
NBIX	Neurocrine Biosciences	1.39%	155.50	0.5%	19.4%	9.6%	29.0%	66.3%	62.0%	223.5%
MDGL	Madrigal Pharmaceuticals	1.39%	513.59	0.0%	-2.7%	-11.8%	85.3%	79.9%	295.8%	3,760.6%
KRYS	Krystal Biotech	1.38%	304.23	0.7%	11.6%	23.4%	140.2%	158.9%	363.8%
TWST	Twist Bioscience	1.34%	58.84	9.6%	-6.0%	85.5%	106.7%	294.1%	-38.3%
PRAX	Praxis Precision Medicines	1.32%	350.56	4.5%	2.9%	18.9%	830.4%	2,104.8%	19.0%
SRRK	Scholar Rock	1.31%	47.72	-1.4%	-0.8%	8.3%	55.3%	537.1%	81.2%
ROIV	Roivant Sciences	1.28%	30.88	-4.7%	5.4%	42.3%	183.0%	219.7%	213.2%
APGE	Apogee Therapeutics	1.27%	82.43	1.3%	-9.3%	9.2%	105.2%
PTCT	PTC Therapeutics	1.26%	69.79	-1.7%	-1.2%	-8.1%	51.0%	18.1%	77.0%	805.2%
IMVT	Immunovant	1.26%	34.13	-4.0%	20.7%	34.3%	136.8%	43.7%	122.2%
MIRM	Mirum Pharmaceuticals	1.23%	100.67	3.8%	7.9%	27.4%	127.2%	260.4%	474.6%
PTGX	Protagonist Therapeutics	1.22%	102.01	1.1%	-3.7%	16.8%	122.6%	298.5%	197.6%

Guidance Updates for XBI Top Holdings

	Ticker	Company	Earnings Date	Guidance Metric	Midpoint Value	% Change	Guidance Change
ALKS_2252026	ALKS	Alkermes	2/25/2026	2026 Total Revenues	1.78 Bil	22.3%	Higher NewNew Guidance Higher than Prior Actual of 1.46 Bil for 2025
TGTX_5062026	TGTX	TG Therapeutics	5/6/2026	Q2 2026 BRIUMVI U.S. Net Product Revenue	220.00 Mil	17.3%	Higher NewNew Guidance Higher than Prior Actual of 187.50 Mil for Q1 2026
TWST_5042026	TWST	Twist Bioscience	5/4/2026	Q3 2026 Revenue	114.50 Mil	6.5%	Higher NewNew Guidance Higher than Prior Actual of 107.50 Mil for Q2 2026

Return vs. Risk

Price Returns Compared

	2021	2022	2023	2024	2025	2026	Total [1]
Returns
XBI Return	-20%	-26%	8%	1%	35%	8%	-6%
Peers Return	33%	-5%	32%	13%	33%	34%	235%
S&P 500 Return	27%	-19%	24%	23%	16%	9%	98%
Monthly Win Rates [3]
XBI Win Rate	33%	50%	50%	50%	67%	100%
Peers Win Rate	63%	48%	58%	57%	67%	64%
S&P 500 Win Rate	75%	42%	67%	75%	67%	60%
Max Drawdowns [4]
XBI Max Drawdown	-37%	-46%	-30%	-20%	-26%	-10%
Peers Max Drawdown	-18%	-35%	-16%	-18%	-27%	-14%
S&P 500 Max Drawdown	-5%	-25%	-10%	-8%	-19%	-9%

[1] Cumulative total returns since the beginning of 2021
[2] Peers: SMH, SOXX, IBB, ITA, XOP.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 5/21/2026 (YTD)

Sharpe Ratios Compared

One measure of reward vs. risk is a Sharpe ratio. A higher ratio indicates better risk-adjusted returns. Most funds have Sharpe ratios < 1.0.

Ticker	1Y	3Y	5Y
XBI	1.79	0.59	0.03
Equity Top Results (3Y)
SPMO	1.93	1.45	0.89
SMH	2.99	1.44	0.91
CGDV	2.12	1.32	0.89
ALLW	1.75	1.29	1.29
DYNF	1.96	1.28	0.68

Results as of 4302026.

Event	XBI	S&P 500
2025 US Tariff Shock
% Loss	-24.6%	-18.8%
% Gain to Breakeven	32.6%	23.1%
Time to Breakeven	147 days	79 days
Summer-Fall 2023 Five Percent Yield Shock
% Loss	-22.9%	-9.5%
% Gain to Breakeven	29.7%	10.5%
Time to Breakeven	47 days	24 days
2023 SVB Regional Banking Crisis
% Loss	-14.5%	-6.7%
% Gain to Breakeven	17.0%	7.1%
Time to Breakeven	48 days	31 days
2022 Inflation Shock & Fed Tightening
% Loss	-45.6%	-24.5%
% Gain to Breakeven	83.8%	32.4%
Time to Breakeven	1290 days	427 days
2020 COVID-19 Crash
% Loss	-32.9%	-33.7%
% Gain to Breakeven	49.1%	50.9%
Time to Breakeven	53 days	140 days
Q4 2018 Fed Policy Error / Growth Scare
% Loss	-31.1%	-19.2%
% Gain to Breakeven	45.0%	23.8%
Time to Breakeven	351 days	105 days

Compare to SMH, SOXX, IBB, ITA, XOP

In The Past

State Street SPDR S&P Biotech ETF's stock fell -24.6% during the 2025 US Tariff Shock. Such a loss loss requires a 32.6% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

Event	XBI	S&P 500
2025 US Tariff Shock
% Loss	-24.6%	-18.8%
% Gain to Breakeven	32.6%	23.1%
Time to Breakeven	147 days	79 days
Summer-Fall 2023 Five Percent Yield Shock
% Loss	-22.9%	-9.5%
% Gain to Breakeven	29.7%	10.5%
Time to Breakeven	47 days	24 days
2022 Inflation Shock & Fed Tightening
% Loss	-45.6%	-24.5%
% Gain to Breakeven	83.8%	32.4%
Time to Breakeven	1290 days	427 days
2020 COVID-19 Crash
% Loss	-32.9%	-33.7%
% Gain to Breakeven	49.1%	50.9%
Time to Breakeven	53 days	140 days
Q4 2018 Fed Policy Error / Growth Scare
% Loss	-31.1%	-19.2%
% Gain to Breakeven	45.0%	23.8%
Time to Breakeven	351 days	105 days
2016-2017 Trump Reflation Bond Selloff
% Loss	-21.4%	-3.7%
% Gain to Breakeven	27.2%	3.9%
Time to Breakeven	11 days	6 days
2015-2016 China Devaluation / Global Growth Scare
% Loss	-42.3%	-12.2%
% Gain to Breakeven	73.2%	13.9%
Time to Breakeven	497 days	62 days
2011 US Debt Ceiling Crisis & European Contagion
% Loss	-26.7%	-17.9%
% Gain to Breakeven	36.5%	21.8%
Time to Breakeven	172 days	123 days
2008-2009 Global Financial Crisis
% Loss	-29.1%	-53.4%
% Gain to Breakeven	41.0%	114.4%
Time to Breakeven	371 days	1085 days

Compare to SMH, SOXX, IBB, ITA, XOP

In The Past

State Street SPDR S&P Biotech ETF's stock fell -24.6% during the 2025 US Tariff Shock. Such a loss loss requires a 32.6% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

XBI Dip Buy History

XBI had 33 events since 2/6/2006 where the dip threshold of -5.0% within 60 days was triggered

30% median peak return within 1 year of dip event
321 days is the median time to peak return after a dip event
-15% median max drawdown within 1 year of dip event

60 Day Dip			XBI Subsequent Performance
Date	XBI	SPY	1Y	Peak Return	Max Drop	# Days to Peak
Median			27%	30%	-15%	321
3242026	-5%	-5%	11%	16%	-1%	24
11152024	-8%	6%	24%	24%	-24%	362
10092024	-5%	2%	9%	11%	-28%	365
4182024	-6%	3%	-7%	25%	-16%	204
8042023	-5%	9%	16%	27%	-21%	207
3102023	-7%	-3%	27%	36%	-15%	354
10032022	-5%	-5%	-13%	15%	-12%	122
11182021	-5%	5%	-34%	0%	-49%	0
9202021	-6%	2%	-36%	4%	-51%	44
3232021	-8%	6%	-33%	1%	-41%	36
2272020	-6%	-5%	69%	99%	-25%	347
9032019	-5%	2%	39%	53%	-16%	321
5132019	-5%	3%	27%	30%	-18%	364
9142018	-5%	5%	-13%	1%	-32%	6
4022018	-5%	-4%	10%	21%	-22%	79
5302017	-5%	2%	40%	44%	0%	244
12122016	-6%	6%	34%	46%	-3%	297
10252016	-8%	-1%	42%	51%	-9%	345
6272016	-6%	-3%	56%	62%	0%	361
8202015	-8%	-4%	-14%	10%	-37%	28
4072014	-8%	1%	72%	80%	-9%	346
12112013	-6%	5%	53%	56%	-1%	363
10232012	-5%	3%	43%	51%	-7%	344
11252011	-5%	-4%	47%	61%	0%	301
8022011	-7%	-6%	29%	38%	-18%	360
5242010	-6%	-2%	38%	41%	-6%	339
10192009	-6%	12%	17%	20%	-10%	155
3022009	-5%	-17%	36%	36%	-2%	365
10032008	-5%	-11%	-11%	0%	-25%	0
1232008	-6%	-11%	-8%	23%	-21%	204
7272007	-5%	-3%	30%	32%	-5%	361
1012007	-5%	6%	29%	35%	-1%	339
5022006	-5%	4%	15%	16%	-9%	365

[1] Dip event defined as first instance dip threshold is triggered within a 60-day time period.
[2] Analysis for period from 1/1/2005 to 5/21/2026

XBI had 21 events since 2/6/2006 where the dip threshold of -10% within 90 days was triggered

35% median peak return within 1 year of dip event
321 days is the median time to peak return after a dip event
-18% median max drawdown within 1 year of dip event

90 Day Dip			XBI Subsequent Performance
Date	XBI	SPY	1Y	Peak Return	Max Drop	# Days to Peak
Median			26%	35%	-18%	321
2252025	-10%	2%	39%	48%	-21%	331
12302024	-12%	6%	41%	41%	-22%	359
9182023	-12%	9%	33%	35%	-16%	162
3232023	-11%	0%	26%	40%	-13%	341
12132022	-10%	-2%	3%	11%	-23%	51
11262021	-10%	6%	-32%	1%	-46%	27
10182021	-10%	6%	-34%	10%	-49%	16
5042021	-14%	14%	-41%	7%	-43%	52
3122020	-13%	-18%	107%	146%	-7%	333
8122019	-11%	1%	33%	46%	-20%	343
10102018	-11%	2%	-10%	10%	-23%	177
9252015	-12%	-9%	1%	8%	-32%	63
8242015	-12%	-9%	-7%	16%	-33%	24
7072014	-10%	8%	67%	73%	-11%	350
5202014	-14%	3%	90%	93%	-0%	303
11152012	-12%	1%	50%	62%	0%	321
8082011	-16%	-15%	57%	69%	0%	354
7062010	-11%	-6%	48%	50%	0%	329
10072008	-11%	-28%	-3%	8%	-18%	345
2202008	-10%	-13%	-3%	30%	-16%	176
6122006	-11%	-3%	20%	24%	-3%	344

[1] Dip event defined as first instance dip threshold is triggered within a 90-day time period.
[2] Analysis for period from 1/1/2005 to 5/21/2026

XBI had 7 events since 2/6/2006 where the dip threshold of -20% within 180 days was triggered

47% median peak return within 1 year of dip event
296 days is the median time to peak return after a dip event
-6.7% median max drawdown within 1 year of dip event

180 Day Dip			XBI Subsequent Performance
Date	XBI	SPY	1Y	Peak Return	Max Drop	# Days to Peak
Median			44%	47%	-7%	296
4012025	-21%	1%	65%	68%	-11%	296
10122023	-23%	10%	44%	50%	-7%	138
10062021	-21%	14%	-32%	10%	-49%	28
3162020	-23%	-17%	122%	164%	0%	329
12212018	-21%	-6%	49%	47%	-0%	364
1082016	-23%	-8%	8%	14%	-24%	258
3022009	-22%	-46%	36%	36%	-2%	365

[1] Dip event defined as first instance dip threshold is triggered within a 180-day time period.
[2] Analysis for period from 1/1/2005 to 5/21/2026

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Current Dip Buy Opportunities Across ETFs

ETFs currently down 5% or more from trailing 6M peaks.

Ticker	Name	Dip %	Mkt Price	Price Date	Peak Price	Peak Date	# Days
NOBL	ProShares S&P 500 Dividend Aristocrats ETF	-5.9%	107.32	5212026	114.03	3012026	81
JEPI	JPMorgan Equity Premium Income ETF	-5.1%	56.08	5212026	59.09	3012026	81
ARKK	ARK Innovation ETF	-7.9%	76.62	5212026	83.21	1132026	128
URA	Global X Uranium ETF	-21.0%	48.86	5212026	61.81	1282026	113
LIT	Global X Lithium & Battery Tech ETF	-7.9%	84.38	5212026	91.62	5112026	10
CGBL	Capital Group Core Balanced ETF	-6.2%	34.41	5212026	36.67	2252026	85
XLF	State Street Financial Select Sector SPDR ETF	-7.8%	51.73	5212026	56.11	1062026	135
XLV	State Street Health Care Select Sector SPDR ETF	-7.1%	148.15	5212026	159.54	3012026	81
XLE	State Street Energy Select Sector SPDR ETF	-5.5%	59.13	5212026	62.56	3292026	53
XLP	State Street Consumer Staples Select Sector SPDR ETF	-5.4%	84.66	5212026	89.51	3012026	81
XLU	State Street Utilities Select Sector SPDR ETF	-5.1%	45.00	5212026	47.40	3012026	81
XLB	State Street Materials Select Sector SPDR ETF	-6.3%	50.02	5212026	53.38	2112026	99
ITA	iShares U.S. Aerospace & Defense ETF	-10.9%	223.15	5212026	250.42	3022026	80
XOP	State Street SPDR S&P Oil & Gas Exploration & Production ETF	-9.3%	170.65	5212026	188.18	3292026	53
TLT	iShares 20+ Year Treasury Bond ETF	-6.6%	84.22	5212026	90.16	3012026	81
VGLT	Vanguard Long-Term Treasury ETF	-5.7%	53.91	5212026	57.20	3012026	81
SPTL	State Street SPDR Portfolio Long Term Treasury ETF	-6.1%	25.61	5212026	27.28	3012026	81
TLH	iShares 10-20 Year Treasury Bond ETF	-5.7%	98.34	5212026	104.25	3012026	81
EDV	Vanguard World Funds Extended Duration ETF	-9.1%	62.11	5212026	68.33	3012026	81
GSG	iShares GSCI Commodity	-5.8%	30.01	5212026	31.85	3182026	64
GLD	SPDR Gold Trust	-15.9%	416.99	5212026	495.90	1292026	112
IAU	iShares Gold Trust	-15.9%	85.43	5212026	101.57	1292026	112
GLDM	SPDR Gold MiniShares Trust	-15.8%	89.87	5212026	106.77	1292026	112
SGOL	ETFS Physical Swiss Gold Shares	-13.1%	44.66	5212026	51.41	1292026	112
BAR	Direxion Daily Gold Bull 3X Shares	-16.6%	44.34	5212026	53.16	1292026	112
SLV	iShares Silver Trust	-34.2%	69.45	5212026	105.60	1282026	113
SIVR	ETFS Physical Silver Shares Trust ETF	-24.8%	83.39	5212026	110.87	1282026	113
PPLT	ETFS Physical Platinum Shares	-29.3%	17.84	5212026	25.23	1252026	116
CPER	United States Copper Index Fund ETV	-13.9%	33.33	5212026	38.71	1292026	112
PALL	ETFS Physical Palladium Shares	-32.2%	25.22	5212026	37.18	1282026	113
USO	United States Oil Fund LP	-6.8%	142.54	5212026	152.96	5192026	2
UNG	United States Natural Gas Fund LP	-33.0%	11.33	5212026	16.90	2012026	109
BNO	United States Brent Oil Fund LP ETV	-7.1%	55.85	5212026	60.13	5042026	17
IBIT	iShares Bitcoin Trust ETF	-20.6%	44.00	5212026	55.44	1142026	127
FBTC	Fidelity Wise Origin Bitcoin Fund	-20.6%	67.56	5212026	85.12	1142026	127
GBTC	Grayscale Bitcoin Trust ETF	-19.0%	61.84	5212026	76.31	1142026	127
ETHA	iShares Ethereum Trust ETF	-36.9%	16.15	5212026	25.59	1142026	127

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About XBI

Holdings Count: 151
Expense Ratio: 0.35%
Inception Date: 2006-01-31

State Street SPDR S&P Biotech ETF
The State Street SPDR S&P Biotech ETF seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of the S&P Biotechnology Select Industry Index (the "Index")Seeks to provide exposure to the Biotechnology segment of the S&P TMI, which comprises the following sub-industries: BiotechnologySeeks to track a modified equal weighted index which provides the potential for unconcentrated industry exposure across large, mid and small cap stocksAllows investors to take strategic or tactical positions at a more targeted level than traditional sector based investing
Asset Class: Equity | ETF Website

Recent Active Movers

Top Gainers

Ticker	Company	Mkt Cap (B)	1D Rtn	YTD Rtn
FBYD	Falcons Beyond Global	0.8	36.6%	27.2%
QBTS	D-Wave Quantum	9.1	33.4%	-1.6%
RGTI	Rigetti Computing	7.3	30.6%	-0.5%
FCEL	FuelCell Energy	1.3	30.5%	260.9%
APLD	Applied Digital	13.5	21.5%	95.8%
QUBT	Quantum Computing	2.5	19.4%	11.2%
WOLF	Wolfspeed	1.9	18.6%	299.2%
HOV	Hovnanian Enterprises	0.7	17.8%	18.4%
ENPH	Enphase Energy	8.2	17.3%	94.5%
AXTI	AXT	5.4	15.7%	640.2%

Top Losers

Ticker	Company	Mkt Cap (B)	1D Rtn	YTD Rtn
INTU	Intuit	85.4	-20.0%	-53.4%
SLS	SELLAS Life Sciences	1.1	-15.7%	100.5%
BVS	Bioventus	0.6	-13.2%	27.6%
NPK	National Presto Industries	0.9	-10.2%	21.5%
GTN-A	Gray Media	0.9	-9.9%	-28.2%
SATS	EchoStar	37.0	-9.4%	18.2%
BORR	Borr Drilling	1.6	-8.7%	40.0%
NN	NextNav	2.9	-7.8%	28.5%
VAL	Valaris	7.1	-7.4%	101.3%
WMT	Walmart	967.2	-7.3%	9.3%

Top Gainers

Ticker	Company	Mkt Cap (B)	1W Rtn	YTD Rtn
FBYD	Falcons Beyond Global	0.8	68.9%	27.2%
TE	T1 Energy	1.9	52.2%	30.5%
RXO	RXO	4.1	39.1%	92.7%
BLDP	Ballard Power Systems	1.6	31.5%	113.8%
SG	Sweetgreen	1.1	30.3%	32.8%
ALAB	Astera Labs	50.5	30.3%	79.0%
RAMP	LiveRamp	2.4	29.9%	28.8%
ENPH	Enphase Energy	8.2	29.8%	94.5%
HIVE	HIVE Digital Technologies	0.9	29.6%	49.2%
SEDG	SolarEdge Technologies	3.8	25.4%	118.4%

Top Losers

Ticker	Company	Mkt Cap (B)	1W Rtn	YTD Rtn
POET	POET Technologies	1.8	-28.0%	134.1%
DSGN	Design Therapeutics	0.6	-24.3%	17.4%
BTGO	BitGo	0.9	-21.3%	-58.0%
FIGR	Figure Technology Solutions	7.4	-20.5%	-15.8%
USAS	Americas Gold And Silver	1.6	-20.1%	11.7%
OPTU	Optimum Communications	0.3	-18.8%	-56.7%
INTU	Intuit	85.4	-18.8%	-53.4%
GTN-A	Gray Media	0.9	-18.6%	-28.2%
SVM	Silvercorp Metals	2.7	-18.2%	46.6%
ONDS	Ondas	3.5	-18.1%	-5.9%

Top Gainers

Ticker	Company	Mkt Cap (B)	1M Rtn	YTD Rtn
MXL	MaxLinear	8.7	194.1%	471.8%
WOLF	Wolfspeed	1.9	150.5%	299.2%
BAND	Bandwidth	1.8	149.0%	278.9%
FCEL	FuelCell Energy	1.3	123.6%	260.9%
INOD	Innodata	3.2	108.2%	93.4%
INTC	Intel	602.3	81.6%	221.1%
VPG	Vishay Precision	1.4	81.5%	170.2%
XMTR	Xometry	4.5	79.6%	46.1%
PENG	Penguin Solutions	2.6	77.0%	149.5%
ENPH	Enphase Energy	8.2	76.3%	94.5%

Top Losers

Ticker	Company	Mkt Cap (B)	1M Rtn	YTD Rtn
CAR	Avis Budget	5.6	-64.5%	22.9%
EMBC	Embecta	0.2	-64.0%	-71.6%
FWRD	Forward Air	0.3	-63.3%	-66.6%
CABO	Cable One	0.3	-58.6%	-57.7%
OPTU	Optimum Communications	0.3	-58.3%	-56.7%
PSIX	Power Solutions International	0.9	-53.1%	-30.7%
TRDA	Entrada Therapeutics	0.3	-51.6%	-38.6%
ERAS	Erasca	3.3	-46.4%	212.0%
BETR	Better Home & Finance	0.4	-45.5%	-23.2%
BRBR	BellRing Brands	1.1	-45.2%	-66.1%

Short Interest

Short Interest: As Of Date	4302026
Short Interest: Shares Quantity	74.8 Mil
Short Interest: % Change Since 4152026	1.9%
Average Daily Volume	7.3 Mil
Days-to-Cover Short Interest	10.2 days

External Quote Links

0	Y Finance	Barrons
1	TradingView	Morningstar
2	SeekingAlpha	ValueLine
3	Motley Fool	Robinhood
4	CNBC	Etrade
5	MarketWatch	Unusual Whales
6	YCharts	Perplexity Finance
7	FinViz

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State Street SPDR S&P Biotech ETF (XBI)

Market Price (5/22/2026): $132.76

State Street SPDR S&P Biotech ETF (XBI)

Market Price (5/22/2026): $132.76

Asset Allocation with XBI

Price Chart

Valuation & Yield

Top 20 Holdings for XBI

Performance for XBI Top Holdings

Guidance Updates for XBI Top Holdings

Return vs. Risk

Price Returns Compared

Sharpe Ratios Compared

How Low Can It Go

In The Past

Preserve Wealth

Asset Allocation

In The Past

Preserve Wealth

Asset Allocation

XBI Dip Buy History

Current Dip Buy Opportunities Across ETFs

Set Alerts and Notifications

Stay Informed

Trade & Investment Ideas

Wealth

Alert Me Periodically

Inform Me Once

About XBI

Latest Trefis Analyses

Recent Active Movers

Top Gainers

Top Losers

Top Gainers

Top Losers

Top Gainers

Top Losers

More From Trefis

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External Quote Links