Tearsheet

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -23%

Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, Biopharmaceutical R&D, Show more.

Weak multi-year price returns
2Y Excs Rtn is -131%, 3Y Excs Rtn is -174%

Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0

Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -15 Mil

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -70%

High stock price volatility
Vol 12M is 2193%

Significant short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 24%

Key risks
PSTV key risks include [1] a stated substantial doubt about its ability to continue as a going concern and [2] potential delisting from Nasdaq for non-compliance with listing requirements.

0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -23%
1 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, Biopharmaceutical R&D, Show more.
2 Weak multi-year price returns
2Y Excs Rtn is -131%, 3Y Excs Rtn is -174%
3 Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
4 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -15 Mil
5 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -70%
6 High stock price volatility
Vol 12M is 2193%
7 Significant short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 24%
8 Key risks
PSTV key risks include [1] a stated substantial doubt about its ability to continue as a going concern and [2] potential delisting from Nasdaq for non-compliance with listing requirements.

Valuation, Metrics & Events

Price Chart

Why The Stock Moved

Qualitative Assessment

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Plus Therapeutics (PSTV) stock has gained about 5% since 1/31/2026 because of the following key factors:

1. Plus Therapeutics reported a significant beat in its Fourth Quarter 2025 earnings. The company announced an Adjusted Earnings Per Share (EPS) of $6.25, substantially surpassing the analyst consensus estimate of a loss of $0.03. Additionally, quarterly revenue reached $1.37 million, exceeding analyst estimates of $1.23 million. This performance represents a 100% earnings surprise.

2. The company made notable advancements in its REYOBIQ clinical development program. Plus Therapeutics completed a Type B meeting with the U.S. Food and Drug Administration (FDA) on January 8, 2026, to discuss the pivotal trial strategy for REYOBIQ in leptomeningeal metastases (LM). The FDA also granted Orphan Drug Designation to REYOBIQ for the treatment of pediatric malignant gliomas on April 8, 2026. The company expects to report data from its ReSPECT-LM Phase 2 trial in the third quarter of 2026 and complete enrollment in its ReSPECT-GBM glioblastoma Phase 2 trial with data anticipated in the fourth quarter of 2026.

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Stock Movement Drivers

Fundamental Drivers

The 7.3% change in PSTV stock from 1/31/2026 to 5/9/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)13120265092026Change
Stock Price ($)5.706.127.3%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)46-22.5%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2026 to 5/9/2026
ReturnCorrelation
PSTV7.3% 
Market (SPY)3.6%1.9%
Sector (XLV)-6.9%-6.2%

Fundamental Drivers

The -54.9% change in PSTV stock from 10/31/2025 to 5/9/2026 was primarily driven by a -22.5% change in the company's Shares Outstanding (Mil).
(LTM values as of)103120255092026Change
Stock Price ($)13.576.12-54.9%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)46-22.5%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

10/31/2025 to 5/9/2026
ReturnCorrelation
PSTV-54.9% 
Market (SPY)5.5%2.1%
Sector (XLV)0.3%-5.5%

Fundamental Drivers

The -66.0% change in PSTV stock from 4/30/2025 to 5/9/2026 was primarily driven by a -94.3% change in the company's Shares Outstanding (Mil).
(LTM values as of)43020255092026Change
Stock Price ($)17.986.12-66.0%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)06-94.3%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

4/30/2025 to 5/9/2026
ReturnCorrelation
PSTV-66.0% 
Market (SPY)30.4%1.5%
Sector (XLV)4.0%-3.6%

Fundamental Drivers

The -93.7% change in PSTV stock from 4/30/2023 to 5/9/2026 was primarily driven by a -98.3% change in the company's Shares Outstanding (Mil).
(LTM values as of)43020235092026Change
Stock Price ($)97.426.12-93.7%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)06-98.3%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

4/30/2023 to 5/9/2026
ReturnCorrelation
PSTV-93.7% 
Market (SPY)78.7%0.8%
Sector (XLV)13.0%-2.0%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
PSTV Return-48%-70%-63%-34%-55%-54%-99%
Peers Return2%11%24%-35%-25%17%-20%
S&P 500 Return27%-19%24%23%16%7%95%

Monthly Win Rates [3]
PSTV Win Rate42%25%50%33%50%40% 
Peers Win Rate33%42%44%44%52%70% 
S&P 500 Win Rate75%42%67%75%67%60% 

Max Drawdowns [4]
PSTV Max Drawdown-49%-71%-79%-43%-84%-99% 
Peers Max Drawdown-28%-41%-27%-54%-51%-15% 
S&P 500 Max Drawdown-1%-25%-1%-2%-15%-7% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: CATX, LNTH, CLRB, ATNM.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 5/8/2026 (YTD)

How Low Can It Go

EventPSTVS&P 500
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-55.8%-9.5%
  % Gain to Breakeven126.0%10.5%
  Time to Breakeven23 days24 days
2020 COVID-19 Crash
  % Loss-50.9%-33.7%
  % Gain to Breakeven103.8%50.9%
  Time to Breakeven14 days140 days
2013 Taper Tantrum
  % Loss-19.5%-0.2%
  % Gain to Breakeven24.3%0.2%
  Time to Breakeven5 days1 days
2011 US Debt Ceiling Crisis & European Contagion
  % Loss-45.3%-17.9%
  % Gain to Breakeven82.9%21.8%
  Time to Breakeven354 days123 days
2010 Eurozone Sovereign Debt Crisis / Flash Crash
  % Loss-39.0%-15.4%
  % Gain to Breakeven63.9%18.2%
  Time to Breakeven167 days125 days
2008-2009 Global Financial Crisis
  % Loss-69.2%-53.4%
  % Gain to Breakeven224.4%114.4%
  Time to Breakeven255 days1085 days

Compare to CATX, LNTH, CLRB, ATNM

In The Past

Plus Therapeutics's stock fell -55.8% during the Summer-Fall 2023 Five Percent Yield Shock. Such a loss loss requires a 126.0% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventPSTVS&P 500
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-55.8%-9.5%
  % Gain to Breakeven126.0%10.5%
  Time to Breakeven23 days24 days
2020 COVID-19 Crash
  % Loss-50.9%-33.7%
  % Gain to Breakeven103.8%50.9%
  Time to Breakeven14 days140 days
2011 US Debt Ceiling Crisis & European Contagion
  % Loss-45.3%-17.9%
  % Gain to Breakeven82.9%21.8%
  Time to Breakeven354 days123 days
2010 Eurozone Sovereign Debt Crisis / Flash Crash
  % Loss-39.0%-15.4%
  % Gain to Breakeven63.9%18.2%
  Time to Breakeven167 days125 days
2008-2009 Global Financial Crisis
  % Loss-69.2%-53.4%
  % Gain to Breakeven224.4%114.4%
  Time to Breakeven255 days1085 days

Compare to CATX, LNTH, CLRB, ATNM

In The Past

Plus Therapeutics's stock fell -55.8% during the Summer-Fall 2023 Five Percent Yield Shock. Such a loss loss requires a 126.0% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Plus Therapeutics (PSTV)

Plus Therapeutics, Inc., a clinical-stage pharmaceutical company, focuses on the development, manufacture, and commercialization of treatments for patients with cancer and other diseases. Its lead drug candidate is Rhenium-186 NanoLiposome, a patented radiotherapy that targets central nervous system cancers, including recurrent glioblastoma, leptomeningeal metastases, and pediatric brain cancers. It has a license agreement with NanoTx, Corp. to develop and commercialize NanoTx's glioblastoma treatment. The company was formerly known as Cytori Therapeutics, Inc. and changed its name to Plus Therapeutics, Inc. in July 2019. Plus Therapeutics, Inc. was founded in 1996 and is headquartered in Austin, Texas.

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Here are 1-3 brief analogies for Plus Therapeutics (PSTV):
  • Imagine a small, R&D-heavy Eli Lilly trying to engineer a breakthrough radioactive drug specifically for central nervous system (CNS) cancers.
  • It's like a specialized, early-stage Genentech, but exclusively focused on developing novel radiation therapies for aggressive brain cancers.
  • Think of a focused biotech startup aiming to do for brain cancer what an early Gilead Sciences did for HIV – tackle a devastating disease with a unique, high-impact therapy.

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  • Rhenium-186 NanoLiposome: A patented radiotherapy drug candidate in development for treating central nervous system cancers, including recurrent glioblastoma, leptomeningeal metastases, and pediatric brain cancers.

AI Analysis | Feedback

Plus Therapeutics, Inc. (PSTV) is a clinical-stage pharmaceutical company focused on the development of treatments. Its lead drug candidate, Rhenium-186 NanoLiposome, is currently in clinical trials for central nervous system cancers.

Given its clinical-stage status, Plus Therapeutics does not currently have major commercial customers in the traditional sense, as its drug candidates are still under development and have not yet received regulatory approval for commercial sale. Therefore, the company does not primarily sell to other companies or directly to individuals. Its activities are focused on research, development, and clinical trials aimed at future commercialization.

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Marc Hedrick, MD, MBA - President and CEO

Dr. Marc Hedrick is the President and CEO at Plus Therapeutics, Inc. He previously held executive leadership roles, including President, CEO, and Director at Cytori Therapeutics, Inc., which was formerly known as Plus Therapeutics. Dr. Hedrick also served as President and CEO of StemSource, Inc. A trained general, vascular, and plastic surgeon, he was a former Associate Professor of Surgery and Pediatrics at the University of California, Los Angeles (UCLA), and Co-Director of the Laboratory of Regenerative Bioengineering and Repair at UCLA.

Andrew Sims, CPA - Vice President and Chief Financial Officer

Mr. Andrew Sims serves as the Vice President and Chief Financial Officer of Plus Therapeutics, Inc. He previously held Chief Financial Officer roles at several private equity-backed companies, including Amplify LLC from 2012 to 2017 and Verbatim Support Services LLC from 2017 to 2019. His professional focus includes mergers and acquisitions, integrations, corporate capitalization, and building and managing teams for global growth. Before joining Plus Therapeutics, Mr. Sims was a Partner at Mazars, a global accounting and advisory firm, where he was the lead partner on over 50 acquisitions.

Russ Havranek, MS MBA - EVP, Commercial and Corporate Strategy

Russ Havranek is the Executive Vice President of Commercial and Corporate Strategy for Plus Therapeutics.

Russell Bradley - President and General Manager, CNSide Diagnostics

Russell Bradley serves as the President and General Manager of CNSide Diagnostics, a wholly-owned subsidiary of Plus Therapeutics. He brings over 30 years of leadership experience in diagnostics and life sciences, with previous senior executive roles at Abbott Laboratories, Luminex Corporation, and Beckman Coulter.

Daniel Ortega, MBA - VP, Development and Technical Operations

Daniel Ortega is the Vice President of Development and Technical Operations at Plus Therapeutics.

AI Analysis | Feedback

The key risks to Plus Therapeutics (PSTV) are:

1. Clinical Trial and Regulatory Risks

As a clinical-stage pharmaceutical company, Plus Therapeutics' success hinges on the favorable outcomes of its ongoing clinical trials for Rhenium-186 NanoLiposome (186RNL) across indications such as recurrent glioblastoma (ReSPECT-GBM), leptomeningeal metastases (ReSPECT-LM), and pediatric brain cancers (ReSPECT-PBC). Any delays, failures, or adverse findings in these trials, or the inability to secure necessary regulatory approvals from bodies like the U.S. Food and Drug Administration (FDA) and European Medicines Agency (EMA), could significantly harm the company's business and prospects.

2. Financial Health and Funding Risks

Plus Therapeutics has a history of incurring net losses and negative cash flow from its operations and is expected to continue doing so for the foreseeable future. The company requires substantial additional funding to finance its product development activities, clinical trials, and general operations. Its ability to continue as a "going concern" is dependent on raising this additional capital and successfully executing its operational plans. Future financing efforts, which are frequently necessary, may lead to significant dilution of existing shareholders' investments.

3. Nasdaq Listing and Share Price Risks

Plus Therapeutics has faced challenges maintaining compliance with Nasdaq's listing standards, including requirements for minimum stockholders' equity. Receiving notices of non-compliance and the risk of delisting from Nasdaq pose a significant threat. Delisting would severely impair the liquidity of its common stock and negatively impact the company's ability to raise capital, further exacerbating its financial risks and potentially leading to a decline in its share price.

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The addressable markets for Plus Therapeutics' main products or services, which target central nervous system cancers, are as follows:

  • Recurrent Glioblastoma: The global recurrent glioblastoma multiforme treatment market was valued at approximately USD 380.6 million in 2025. The top 7 markets (U.S., EU4, UK, and Japan) for recurrent glioblastoma are projected to grow at a Compound Annual Growth Rate (CAGR) of 6.06% from 2025 to 2035. The United States represents the largest market for this treatment.
  • Leptomeningeal Metastases: The global market for leptomeningeal metastases management is valued at approximately USD 2.5 billion in 2024 and is expected to reach around USD 4.5 billion by 2034. The market in the 7MM (U.S., EU4, UK, and Japan) was approximately USD 1.7 billion in 2024. The United States accounts for the largest market size within the 7MM, representing 60% of it.
  • Pediatric Brain Cancers: The global pediatric brain tumors market is estimated to be valued at USD 1.66 billion in 2025 and is projected to reach USD 2.68 billion by 2032, with a CAGR of 7.1% from 2025 to 2032. North America holds a dominant position in this market, accounting for approximately 40% of the global market share in 2023.

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Here are 3-5 expected drivers of future revenue growth for Plus Therapeutics (PSTV) over the next 2-3 years:
  1. Advancement and Potential Commercialization of REYOBIQ for Leptomeningeal Metastases (LM): Plus Therapeutics is actively progressing its lead drug candidate, Rhenium-186 NanoLiposome (REYOBIQ), through clinical trials for leptomeningeal metastases (LM). The company plans to complete its Phase 1 LM trials and transition to later-stage trials in 2025. The FDA has already granted Orphan Drug Designation to REYOBIQ for the treatment of LM, which could facilitate its development and market access. Furthermore, Plus Therapeutics has reached an agreement with the FDA to initiate a Phase 1 multiple-dose administration trial for ReSPECT-LM, with site start-up currently underway. The company anticipates completing Phase 2 in 2025. This progression towards regulatory approval and eventual market launch represents a significant potential revenue stream addressing an unmet medical need.
  2. Launch and Commercialization of CNSide Diagnostic Test: Plus Therapeutics has acquired the assets necessary to exclusively commercialize CNSide, a novel diagnostic for leptomeningeal metastases. Positive topline results from the FORESEE trial for the CNSide diagnostic have been reported. The company is planning a limited launch of the CNSide diagnostic test in 2025 and is working towards CLIA compliance certification for its Houston-based clinical laboratory, which is crucial for the commercialization of this diagnostic tool. The CNSide platform is viewed as a feasible, clinically relevant, and scalable tool for managing leptomeningeal disease.
  3. Advancement of REYOBIQ for Pediatric Brain Cancers: Plus Therapeutics is developing REYOBIQ for pediatric brain cancers, including high-grade glioma and ependymoma. The company secured a $3 million grant from the U.S. Department of Defense to support a Phase 1 trial for these pediatric indications. An Investigational New Drug (IND) application for the ReSPECT-PBC pediatric brain cancer trial is under review, with ongoing interactions with the FDA towards final IND approval. The anticipated progression of this program lays the groundwork for future market entry and revenue generation in this specialized area.
  4. Continued Growth in Grant Revenue: As a clinical-stage company, grant revenue plays a crucial role in funding Plus Therapeutics' research and development efforts. The company reported $5.8 million in grant revenue in 2024, an increase from $4.9 million in 2023. For 2025, Plus Therapeutics expects grant revenue to be in the range of $6 million to $8 million, indicating a consistent and growing financial contribution that supports the advancement of its product pipeline towards commercialization. These grants primarily originate from sources such as the Cancer Prevention & Research Institute of Texas (CPRIT) and the U.S. Department of Defense.

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Share Repurchases

  • Plus Therapeutics announced an Equity Buyback for $0.5 million worth of its shares on November 4, 2023.

Share Issuance

  • In March 2025, Plus Therapeutics completed an underwritten equity financing, raising approximately $15.0 million in gross proceeds.
  • In June 2025, the company announced a comprehensive restructuring of its March 2025 equity financing to eliminate potential dilution of up to 1.5 billion shares of common stock, involving the cancellation of warrants and approximately 25 million shares of common stock.
  • In August 2025, stockholders approved the potential issuance of up to $50.0 million of common stock to Lincoln Park Capital under a purchase agreement.

Inbound Investments

  • Plus Therapeutics completed an underwritten equity financing, raising approximately $15.0 million in gross proceeds in March 2025.
  • As of September 30, 2025, the company held $16.6 million in cash and investments, partially supported by non-dilutive funding, including a $1.9 million advance from a $17.6 million Cancer Prevention and Research Institute of Texas (CPRIT) grant.
  • Grant revenue was $5.2 million for the year 2025, $5.8 million in 2024, and $4.9 million in 2023.

Capital Expenditures

  • Plus Therapeutics Inc invested $27K in capital expenditures in Q3 2025.
  • In the 12 months prior to a 2026 reporting date, capital expenditures were -$48,000.
  • The company anticipates increased research and development expenditures in 2026 compared to 2025, focusing on the ReSPECT-LM clinical trial, manufacturing scale-up for REYOBIQ, and initial enrollments in the ReSPECT-PBC clinical trial, along with expanding CNSide research and development teams.

Latest Trefis Analyses

TitleDate
0DASHBOARDS 
1Plus Therapeutics Earnings Notes12/16/2025
Title
0ARTICLES

Trade Ideas

Select ideas related to PSTV.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
GEHC_4302026_Dip_Buyer_FCFYield04302026GEHCGE HealthCare TechnologiesDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
0.0%0.0%0.0%
IQV_4302026_Dip_Buyer_FCFYield04302026IQVIQVIADip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
0.0%0.0%0.0%
UHS_4302026_Dip_Buyer_FCFYield04302026UHSUniversal Health ServicesDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
0.0%0.0%0.0%
ABT_4302026_Dip_Buyer_ValueBuy04302026ABTAbbott LaboratoriesDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
0.0%0.0%0.0%
ZBIO_4302026_Insider_Buying_45D_2Buy_200K04302026ZBIOZenas BioPharmaInsiderInsider Buys 45DStrong Insider Buying
Companies with multiple insider buys in the last 45 days
0.0%0.0%0.0%

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

PSTVCATXLNTHCLRBATNMMedian
NamePlus The.Perspect.Lantheus Cellecta.Actinium. 
Mkt Price6.123.7693.063.101.313.76
Mkt Cap0.00.36.00.00.00.0
Rev LTM001,546000
Op Inc LTM-15-114290-23-26-23
FCF LTM-21-95372-23-23-23
FCF 3Y Avg-15-69356-34-32-32
CFO LTM-21-82408-23-23-23
CFO 3Y Avg-15-46419-34-32-32

Growth & Margins

PSTVCATXLNTHCLRBATNMMedian
NamePlus The.Perspect.Lantheus Cellecta.Actinium. 
Rev Chg LTM--0.6%--0.6%
Rev Chg 3Y Avg--15.4%--15.4%
Rev Chg Q--1.2%--1.2%
QoQ Delta Rev Chg LTM--0.3%-0.0%0.1%
Op Inc Chg LTM-4.1%-70.0%-36.2%55.6%48.1%-4.1%
Op Inc Chg 3Y Avg6.0%-157.4%512.9%-4.2%8.8%6.0%
Op Mgn LTM--18.8%--28,346.7%-14,164.0%
Op Mgn 3Y Avg--27.7%--27.7%
QoQ Delta Op Mgn LTM---1.7%-11,927.8%5,963.0%
CFO/Rev LTM--26.4%--25,417.8%-12,695.7%
CFO/Rev 3Y Avg--28.1%--28.1%
FCF/Rev LTM--24.0%--25,420.0%-12,698.0%
FCF/Rev 3Y Avg--23.9%--23.9%

Valuation

PSTVCATXLNTHCLRBATNMMedian
NamePlus The.Perspect.Lantheus Cellecta.Actinium. 
Mkt Cap0.00.36.00.00.00.0
P/S--3.9-454.7229.3
P/Op Inc-2.2-2.520.8-0.6-1.6-1.6
P/EBIT-1.8-2.715.3-0.6-1.6-1.6
P/E-1.5-2.721.6-0.6-1.7-1.5
P/CFO-1.6-3.414.8-0.6-1.8-1.6
Total Yield-65.9%-36.9%4.6%-165.8%-57.4%-57.4%
Dividend Yield0.0%0.0%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg-3,359.5%-37.4%6.8%-4,647.3%-52.7%-52.7%
D/E0.00.00.10.00.00.0
Net D/E-0.2-0.50.0-1.0-1.0-0.5

Returns

PSTVCATXLNTHCLRBATNMMedian
NamePlus The.Perspect.Lantheus Cellecta.Actinium. 
1M Rtn56.1%-16.3%14.3%9.9%14.9%14.3%
3M Rtn-5.8%-20.2%43.4%2.0%13.9%2.0%
6M Rtn-54.5%71.7%82.2%-8.6%4.0%4.0%
12M Rtn-62.9%60.0%13.8%-58.2%-11.5%-11.5%
3Y Rtn-95.0%-42.2%-6.0%-92.6%-84.5%-84.5%
1M Excs Rtn47.7%-24.7%5.9%1.5%6.5%5.9%
3M Excs Rtn-12.5%-26.9%36.7%-4.8%7.2%-4.8%
6M Excs Rtn-63.9%52.5%53.7%-16.1%-11.1%-11.1%
12M Excs Rtn-88.0%28.6%-15.8%-89.1%-37.8%-37.8%
3Y Excs Rtn-174.3%-119.4%-68.1%-174.0%-166.3%-166.3%

Comparison Analyses

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Financials

Segment Financials

Assets by Segment
$ Mil20252024202320222021
Development, manufacturing and commercialization of complex and innovative treatments for patients7    
Single Segment 11242212
Total711242212


Price Behavior

Price Behavior
Market Price$6.12 
Market Cap ($ Bil)0.0 
First Trading Date11/16/2000 
Distance from 52W High-72.5% 
   50 Days200 Days
DMA Price$5.56$10.99
DMA Trenddowndown
Distance from DMA10.1%-44.3%
 3M1YR
Volatility4,413.4%2,202.0%
Downside Capture9.274.73
Upside Capture1578.33551.80
Correlation (SPY)1.8%1.7%
PSTV Betas & Captures as of 4/30/2026

 1M2M3M6M1Y3Y
Beta-68.254.025.905.102.630.69
Up Beta-190.21-151.20-114.15-60.93-29.54-4.95
Down Beta44.3621.0316.489.214.680.41
Up Capture13884%11018%10765%6741%7001%420%
Bmk +ve Days15223166141428
Stock +ve Days12203260115343
Down Capture-2356%752%511%318%221%113%
Bmk -ve Days4183056108321
Stock -ve Days10233265137388

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with PSTV
PSTV-56.7%2,193.2%0.97-
Sector ETF (XLV)7.9%15.4%0.30-4.1%
Equity (SPY)29.0%12.5%1.831.4%
Gold (GLD)39.8%27.0%1.22-6.6%
Commodities (DBC)50.6%18.0%2.2111.7%
Real Estate (VNQ)13.0%13.5%0.669.4%
Bitcoin (BTCUSD)-17.4%42.1%-0.34-2.7%

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Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with PSTV
PSTV-63.8%997.8%0.44-
Sector ETF (XLV)4.9%14.6%0.16-1.0%
Equity (SPY)12.8%17.1%0.591.4%
Gold (GLD)20.9%17.9%0.95-4.4%
Commodities (DBC)13.8%19.1%0.595.4%
Real Estate (VNQ)3.4%18.8%0.083.4%
Bitcoin (BTCUSD)7.0%56.0%0.34-0.4%

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Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with PSTV
PSTV-69.6%715.7%0.28-
Sector ETF (XLV)9.3%16.5%0.461.3%
Equity (SPY)15.1%17.9%0.722.9%
Gold (GLD)13.4%15.9%0.69-2.9%
Commodities (DBC)9.3%17.8%0.445.0%
Real Estate (VNQ)5.8%20.7%0.243.5%
Bitcoin (BTCUSD)67.8%66.9%1.070.2%

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Short Interest

Short Interest: As Of Date4152026
Short Interest: Shares Quantity1.3 Mil
Short Interest: % Change Since 3312026-94.4%
Average Daily Volume0.9 Mil
Days-to-Cover Short Interest1.5 days
Basic Shares Quantity5.5 Mil
Short % of Basic Shares24.3%

Earnings Returns History

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 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
3/12/2026-15.2%-18.2%-26.6%
10/30/20252.5%-3.1%11.3%
8/14/202515.8%-10.9%-23.8%
3/27/2025-23.7%-49.0%-44.5%
11/14/2024-7.1%-4.8%-7.1%
8/14/2024-1.4%2.8%4.2%
5/15/2024-3.0%-6.0%-13.8%
3/5/2024-11.2%-18.8%-12.2%
...
SUMMARY STATS   
# Positive554
# Negative141415
Median Positive3.9%5.2%25.3%
Median Negative-6.5%-12.7%-16.7%
Max Positive15.8%39.3%41.2%
Max Negative-23.7%-49.0%-44.5%

SEC Filings

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Report DateFiling DateFiling
12/31/202503/12/202610-K
09/30/202510/30/202510-Q
06/30/202508/14/202510-Q
03/31/202505/30/202510-Q
12/31/202403/31/202510-K
09/30/202411/14/202410-Q
06/30/202408/14/202410-Q
03/31/202405/15/202410-Q
12/31/202303/05/202410-K
09/30/202310/31/202310-Q
06/30/202308/14/202310-Q
03/31/202304/20/202310-Q
12/31/202202/23/202310-K
09/30/202210/20/202210-Q
06/30/202207/21/202210-Q
03/31/202204/21/202210-Q

Insider Activity

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#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Sims, Andrew John Hugh MacIntyreChief Financial OfficerDirectBuy110520250.5120,00010,20034,750Form
2Lenk, Robert P DirectBuy82520250.49110,00053,77968,117Form