Tearsheet

Harvard Bioscience (HBIO)


Market Price (4/23/2026): $6.67 | Market Cap: $297.5 Mil
Sector: Health Care | Industry: Health Care Equipment

Harvard Bioscience (HBIO)


Market Price (4/23/2026): $6.67
Market Cap: $297.5 Mil
Sector: Health Care
Industry: Health Care Equipment

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Biopharmaceutical R&D, Gene Editing & Therapy, Show more.

Weak multi-year price returns
2Y Excs Rtn is -126%, 3Y Excs Rtn is -158%

Expensive valuation multiples
P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 44x

Weak revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is -8.1%, Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -8.4%, Rev Chg QQuarterly Revenue Change % is -3.3%

Valuation getting more expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is 1442%

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -23%

High stock price volatility
Vol 12M is 175%

Key risks
HBIO key risks include [1] substantial doubt about its ability to continue as a going concern due to a critical need to refinance significant debt and [2] potential delisting from the Nasdaq exchange.

0 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Biopharmaceutical R&D, Gene Editing & Therapy, Show more.
1 Weak multi-year price returns
2Y Excs Rtn is -126%, 3Y Excs Rtn is -158%
2 Expensive valuation multiples
P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 44x
3 Weak revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is -8.1%, Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -8.4%, Rev Chg QQuarterly Revenue Change % is -3.3%
4 Valuation getting more expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is 1442%
5 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -23%
6 High stock price volatility
Vol 12M is 175%
7 Key risks
HBIO key risks include [1] substantial doubt about its ability to continue as a going concern due to a critical need to refinance significant debt and [2] potential delisting from the Nasdaq exchange.

Valuation, Metrics & Events

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Harvard Bioscience (HBIO) stock has remained largely at the same level since 12/31/2025 because of the following key factors:

1. Mixed Q4 2025 Financial Results and Modest 2026 Guidance.

Harvard Bioscience reported a decline in full-year 2025 revenue to $86.6 million from $94.1 million in 2024, alongside a significant GAAP net loss of $56.7 million, largely driven by a $48.0 million goodwill impairment. While the fourth quarter of 2025 showed some operational strength, with revenue of $23.7 million exceeding the midpoint of guidance and adjusted EBITDA growing 27% year-over-year to $3.8 million, the company's full-year 2026 guidance projects only modest revenue growth of 2% to 4% and adjusted EBITDA growth of 6% to 10%. This blend of past challenges and a cautiously optimistic, rather than transformative, outlook for 2026 likely contributed to the stock's largely stable performance.

2. Impact of Reverse Stock Split.

Harvard Bioscience implemented a reverse stock split, with the common stock beginning to trade on a post-split adjusted basis on March 16, 2026. While a reverse split mechanically increases the nominal share price, it is often undertaken to meet exchange listing requirements or enhance investor perception, rather than reflecting an underlying improvement in fundamental value. This event likely introduced a degree of investor caution or uncertainty, potentially offsetting any positive sentiment from operational improvements and leading to a relatively flat underlying stock movement.

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Stock Movement Drivers

Fundamental Drivers

The 0.0% change in HBIO stock from 12/31/2025 to 4/22/2026 was primarily driven by a 910.9% change in the company's P/S Multiple.
(LTM values as of)123120254222026Change
Stock Price ($)6.696.690.0%
Change Contribution By: 
Total Revenues ($ Mil)8787-0.9%
P/S Multiple0.33.4910.9%
Shares Outstanding (Mil)445-90.0%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

12/31/2025 to 4/22/2026
ReturnCorrelation
HBIO0.0% 
Market (SPY)-5.4%24.2%
Sector (XLV)-5.4%10.2%

Fundamental Drivers

The 52.6% change in HBIO stock from 9/30/2025 to 4/22/2026 was primarily driven by a 1475.1% change in the company's P/S Multiple.
(LTM values as of)93020254222026Change
Stock Price ($)4.386.6952.6%
Change Contribution By: 
Total Revenues ($ Mil)8987-2.5%
P/S Multiple0.23.41475.1%
Shares Outstanding (Mil)445-90.1%
Cumulative Contribution52.6%

LTM = Last Twelve Months as of date shown

Market Drivers

9/30/2025 to 4/22/2026
ReturnCorrelation
HBIO52.6% 
Market (SPY)-2.9%13.6%
Sector (XLV)5.6%15.4%

Fundamental Drivers

The 18.2% change in HBIO stock from 3/31/2025 to 4/22/2026 was primarily driven by a 1213.5% change in the company's P/S Multiple.
(LTM values as of)33120254222026Change
Stock Price ($)5.666.6918.2%
Change Contribution By: 
Total Revenues ($ Mil)9487-8.1%
P/S Multiple0.33.41213.5%
Shares Outstanding (Mil)445-90.2%
Cumulative Contribution18.2%

LTM = Last Twelve Months as of date shown

Market Drivers

3/31/2025 to 4/22/2026
ReturnCorrelation
HBIO18.2% 
Market (SPY)16.3%25.8%
Sector (XLV)1.6%20.5%

Fundamental Drivers

The -84.1% change in HBIO stock from 3/31/2023 to 4/22/2026 was primarily driven by a -90.7% change in the company's Shares Outstanding (Mil).
(LTM values as of)33120234222026Change
Stock Price ($)42.006.69-84.1%
Change Contribution By: 
Total Revenues ($ Mil)11387-23.6%
P/S Multiple1.53.4123.7%
Shares Outstanding (Mil)445-90.7%
Cumulative Contribution-84.1%

LTM = Last Twelve Months as of date shown

Market Drivers

3/31/2023 to 4/22/2026
ReturnCorrelation
HBIO-84.1% 
Market (SPY)63.3%23.9%
Sector (XLV)18.4%19.9%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
HBIO Return64%-61%93%-61%-68%-2%-85%
Peers Return42%-19%-8%2%2%-9%0%
S&P 500 Return27%-19%24%23%16%3%88%

Monthly Win Rates [3]
HBIO Win Rate67%33%42%8%42%50% 
Peers Win Rate77%40%50%47%50%30% 
S&P 500 Win Rate75%42%67%75%67%50% 

Max Drawdowns [4]
HBIO Max Drawdown-9%-70%-12%-63%-87%-36% 
Peers Max Drawdown-4%-33%-28%-10%-27%-20% 
S&P 500 Max Drawdown-1%-25%-1%-2%-15%-7% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: TMO, A, BIO, DHR, WAT.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 4/22/2026 (YTD)

How Low Can It Go

Unique KeyEventHBIOS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-75.0%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven299.5%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-56.8%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven131.7%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven104 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-76.1%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven318.2%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven616 days120 days
2008 Global Financial Crisis2008 Global Financial Crisis  
2008 Global Financial Crisis% Loss% Loss-67.3%-56.8%
2008 Global Financial Crisis% Gain to Breakeven% Gain to Breakeven206.2%131.3%
2008 Global Financial CrisisTime to BreakevenTime to Breakeven858 days1,480 days

Compare to TMO, A, BIO, DHR, WAT

In The Past

Harvard Bioscience's stock fell -75.0% during the 2022 Inflation Shock from a high on 8/12/2021. A -75.0% loss requires a 299.5% gain to breakeven.

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About Harvard Bioscience (HBIO)

Harvard Bioscience, Inc. develops, manufactures, and sells technologies, products, and services that enables fundamental research, discovery, and pre-clinical testing for drug development in the United States and internationally. The company offers cellular and molecular technology instruments, such as syringe and peristaltic pump products, as well as a range of instruments and accessories for tissue and organ-based lab research, including surgical products, infusion systems, and behavior research systems; and spectrophotometers, microplate readers, amino acid analyzers, gel electrophoresis equipment, and electroporation and electrofusion instruments. It also engages in the development and manufacture of precision scientific measuring instrumentation and equipment, which cover data acquisition systems with custom amplifier configurations for cellular analysis, micro electrode array solutions for in vivo recordings, and vitro-systems for extracellular recordings; and offers preclinical products. The company markets its products through sales organizations, websites, catalogs, and distributors to research scientists in pharmaceutical and biotechnology companies, universities, hospitals, and government laboratories, as well as to contract research organizations, academic labs, and government researchers. It primarily sells its products under Harvard Apparatus, DSI, Ponemah, Buxco, Biochrom, BTX, and MCS brand names. The company was founded in 1901 and is headquartered in Holliston, Massachusetts.

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Think of them as a smaller-scale Thermo Fisher Scientific or Danaher, providing the essential scientific instruments and lab equipment that researchers use for drug discovery and pre-clinical testing.

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  • Lab Research Instruments: A range of tools including syringe and peristaltic pumps, surgical products, infusion systems, and behavior research systems for tissue and organ-based lab research.
  • Cellular and Molecular Analysis Instruments: Products such as spectrophotometers, microplate readers, amino acid analyzers, and gel electrophoresis equipment for fundamental research.
  • Electroporation and Electrofusion Instruments: Specialized devices used to introduce substances into cells or fuse cells using electrical pulses.
  • Precision Scientific Measuring Instrumentation: Equipment covering data acquisition systems with custom amplifier configurations, micro electrode array solutions, and vitro-systems for cellular recordings.
  • Preclinical Testing Products: Technologies, products, and services specifically designed for early-stage drug development and testing.

AI Analysis | Feedback

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Harvard Bioscience (HBIO) primarily sells its products and services to research scientists within various organizations and institutions rather than directly to individuals. The company's major customers fall into the following categories:

  • Pharmaceutical and biotechnology companies
  • Universities and academic laboratories
  • Hospitals
  • Government laboratories and researchers
  • Contract research organizations (CROs)

The provided company description does not list specific names of customer companies, only the categories of organizations they serve.

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John Duke, President & Chief Executive Officer

John Duke was appointed President and Chief Executive Officer of Harvard Bioscience, as well as a member of its Board of Directors, in 2025. Previously, Mr. Duke served as the Chief Executive Officer of Plastic Molding Technology (PMT), where he achieved approximately 20% annual revenue growth during his tenure. Before joining PMT, he was the Executive Vice President and Chief Business Officer of Lyten, Inc., an advanced materials company. Mr. Duke also spent over 20 years at Corning Incorporated, holding various leadership positions including Corporate Vice President, Corporate Officer, VP & GM - Glass Microsystems, and Vice President, Business Operations - Corning Life Sciences.

Mark Frost, Chief Financial Officer & Treasurer

Mark Frost was appointed Chief Financial Officer and Treasurer of Harvard Bioscience, effective March 6, 2026, after serving as Interim CFO & Treasurer from April 10, 2025. He brings over 30 years of financial and executive-level management experience from both private and public companies. Prior to joining Harvard Bioscience, Mr. Frost served as the Chief Financial Officer of Fathom (NYSE:FATH), a digital manufacturing company, and before that, as CFO for Argon Medical Devices, a medical devices company that was planning to go public.

Nitya Shetty, Vice President, Global Research and Development

Nitya Shetty joined Harvard Bioscience in October 2021 as Vice President, Global Research and Development. Her background includes 15 years at Spacelabs Healthcare, where she specialized in Patient Monitoring, and seven years at GE Consumer & Industrial. Ms. Shetty has experience in developing innovative and high-performance R&D centers across multiple geographies that support revenue generation.

Ryan Wallace, Senior Vice President Global Sales, Preclinical Systems

Ryan Wallace was named Senior Vice President Global Sales, Preclinical Systems in April 2020. In this role, he is responsible for leading Harvard Bioscience's global direct sales efforts, with a focus on leading Clinical Research Organizations (CROs), pharmaceutical companies, and certain strategic accounts.

Diane Houston, Senior Director of Applications and Business Intelligence (Implied from search results as a key leader, actual title from company website not explicitly provided in snippets)

Diane Houston has extensive experience transforming sales analytics and fleet management, and has led numerous projects resulting in significant cost reductions. Before joining Harvard Bioscience, she held leadership roles in both private and public companies, including Kaz, Paychex, and Oracle, and spent half of her career as a consultant, leading small teams through significant systems changes for a wide range of businesses.

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Harvard Bioscience (HBIO) faces several key risks to its business operations and financial stability.

The most significant risk stems from the company's **financial health and high leverage**. Harvard Bioscience has been characterized by struggles for consistent profitability and efficient growth, with profit margins considerably thinner than the industry average. The company carries a notable debt load, which poses financial risk, especially in a volatile market environment. Its financial strength is rated as poor due to high leverage and liquidity concerns, and there has been a high probability of financial distress indicated by analytical models. While recent debt refinancing has occurred, the underlying issues of high leverage and operational costs relative to revenue continue to present a substantial challenge.

Another key risk is the **intense competitive landscape and limited organic growth potential**. Harvard Bioscience operates as a smaller provider in the vast life sciences tools and bioprocess market, which is dominated by larger entities with immense resources. This niche focus, while offering some insulation from direct competition, also caps the company's growth potential and limits its ability to achieve significant economies of scale. The company's revenue growth has been modest, sometimes stagnant, and heavily reliant on acquisitions rather than organic expansion. In 2025, the company experienced a decline in revenue, signaling weaker demand from distributors, contract research organizations (CROs), and academic institutions. Analysts forecast Harvard Bioscience's revenue to grow slower than the broader U.S. market.

Finally, Harvard Bioscience has faced risks associated with its **Nasdaq listing and share price volatility**, which can impact investor confidence and capital-raising abilities. The company previously received a notification from Nasdaq regarding non-compliance with the minimum bid price requirement, which could have led to delisting. Although the company received an extension and implemented a reverse stock split to regain compliance, the necessity of such actions highlights underlying concerns about its market valuation, liquidity, and ability to raise capital. Such events can also negatively affect employee morale, customer trust, and business development opportunities.

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Harvard Bioscience (HBIO) operates within several addressable markets related to life sciences research and drug development. Below are the estimated market sizes for their main product and service categories:

  • The global Scientific Instruments Market was valued at approximately USD 43.28 billion in 2024 and is projected to reach USD 66 billion by 2033, growing at a compound annual growth rate (CAGR) of 4.8% during the forecast period (2026–2033).
  • The global Cell Analysis Instruments Market is expected to grow from USD 22.94 billion in 2025 to USD 34.49 billion by 2031, at a CAGR of 7.02% over 2026-2031.
  • The global Preclinical Assets Market was valued at USD 5.87 billion in 2024 and is projected to grow to USD 9.3 billion by 2029, with a CAGR of 9.8%.
  • The global Preclinical CRO Market is estimated at USD 8.20 billion in 2026 and is expected to reach USD 11.74 billion by 2031, growing at a CAGR of 7.45% during the forecast period (2026-2031). Another estimate indicates the market was USD 10.11 billion in 2025 and is projected to increase to USD 32.61 billion by 2034, demonstrating a CAGR of 13.90% between 2026-2034.
  • The global Precision Measuring Tools Market was valued at USD 9.89 billion in 2025 and is expected to grow to USD 13.9 billion by 2030, at a CAGR of 7%.
  • The global Biotechnology Instruments Market was valued at USD 61.1 billion in 2022 and is expected to grow at a CAGR of over 4.4% between 2023 and 2032, reaching USD 96.1 billion by 2032. Another report indicates the market size was USD 80.76 billion in 2024 and is expected to grow to USD 173.96 billion by 2033, at a CAGR of 8.9% during the forecast period (2025-2033).
  • The global Cell Processing Instruments Market was valued at USD 6.39 billion in 2024 and is anticipated to grow from USD 6.82 billion in 2025 to USD 12.49 billion by 2034, exhibiting a CAGR of 7.0% during 2025–2034.
  • The global Laboratory Equipment Market size is estimated at USD 35.90 billion in 2025 and is predicted to increase to approximately USD 74.22 billion by 2035, expanding at a CAGR of 7.53% between 2026 to 2035.
  • The global Tissue Diagnostics Market is expected to grow from USD 6.45 billion in 2025 to USD 9.33 billion by 2031, reflecting a 6.35% CAGR (2026-2031). Another source projects a valuation of USD 10.86 billion by 2030, growing at a CAGR of 10.0% from 2025.

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Here are the expected drivers of future revenue growth for Harvard Bioscience (HBIO) over the next 2-3 years:

  • Expansion of New Product Innovation (NPI) and Focus on Translational Science: Harvard Bioscience anticipates revenue growth to be driven by new product innovation, particularly in the translational science market. This includes accelerating revenue from its NPI pipeline, which features offerings such as MeshMEA and organoid research platforms, as well as next-generation telemetry and bioproduction tools.
  • Stabilized NIH Funding Environment: The company expects revenue growth to be supported by a stabilized funding environment from the National Institutes of Health (NIH), which historically impacts orders from academic and government research laboratories.
  • Increasing Mix of Higher-Margin Recurring Revenue: Harvard Bioscience is strategically shifting towards higher-margin consumables, software, and services, aiming to increase the proportion of recurring revenue within its total sales.
  • Operational Efficiencies and Cost Reductions: Initiatives such as the strategic consolidation of manufacturing operations, including the phased closure of the Holliston, Massachusetts facility, are expected to yield significant cost savings. These efficiencies can enhance financial flexibility and enable further investment in growth opportunities, indirectly contributing to revenue expansion.

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Share Issuance

  • Harvard Bioscience completed a 1-for-10 reverse stock split, approved on March 6, 2026, and effective March 13, 2026, to regain compliance with Nasdaq's minimum bid price requirement.
  • This action reduced the number of outstanding common shares from approximately 44,719,894 to approximately 4,471,989.

Inbound Investments

  • The company completed a comprehensive debt refinancing in December 2025, which extended its debt maturity to 2029.
  • This refinancing is expected to reduce annual debt service by $3 million, generating annual cash savings.
  • As of December 31, 2025, Harvard Bioscience had $40.0 million in outstanding borrowings under its Credit Agreement.

Capital Expenditures

  • Harvard Bioscience launched "Project Viking" in January 2026, a strategic initiative to consolidate its manufacturing footprint.
  • Project Viking is anticipated to generate approximately $3 million in cost savings in 2027 and $4 million annually from 2028 onwards, with estimated pre-tax restructuring charges of $3.4 million to $4.4 million.
  • Cash used in investing activities for periods ending December 31, 2025, included amounts of $599,000, $466,000, $1,863,000, and $1,344,000.

Better Bets vs. Harvard Bioscience (HBIO)

Latest Trefis Analyses

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Trade Ideas

Select ideas related to HBIO.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
PGNY_3312026_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG03312026PGNYProgynyDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
0.0%0.0%0.0%
CNC_3272026_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG03272026CNCCenteneDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
2.3%2.3%-0.6%
OSCR_3272026_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG03272026OSCROscar HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
3.0%3.0%-2.6%
WAT_3202026_Monopoly_xInd_xCD_Getting_Cheaper03202026WATWatersMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-0.4%-0.4%-3.3%
GILD_3202026_Quality_Momentum_RoomToRun_10%03202026GILDGilead SciencesQualityQ | Momentum | UpsideQuality Stocks with Momentum and Upside
Buying quality stocks with strong momentum but still having room to run
1.6%1.6%-2.2%

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

HBIOTMOABIODHRWATMedian
NameHarvard .Thermo F.Agilent .Bio-Rad .Danaher Waters  
Mkt Price6.69513.98120.47300.78184.04334.38242.41
Mkt Cap0.3192.234.18.1130.319.927.0
Rev LTM8744,5557,0652,58324,7783,1655,115
Op Inc LTM08,1091,4562194,7608031,129
FCF LTM56,2939933755,291540766
FCF 3Y Avg56,8291,3182865,247534926
CFO LTM77,8181,3965326,4396531,024
CFO 3Y Avg78,2971,6854546,5486721,179

Growth & Margins

HBIOTMOABIODHRWATMedian
NameHarvard .Thermo F.Agilent .Bio-Rad .Danaher Waters  
Rev Chg LTM-8.1%3.9%8.1%0.7%4.0%7.0%4.0%
Rev Chg 3Y Avg-8.4%-0.2%0.8%-2.6%-0.1%2.2%-0.2%
Rev Chg Q-3.3%7.2%7.0%3.9%3.7%6.8%5.3%
QoQ Delta Rev Chg LTM-0.9%1.9%1.7%1.0%0.9%1.9%1.3%
Op Inc Chg LTM101.6%5.1%-1.6%-18.7%-1.3%-4.2%-1.5%
Op Inc Chg 3Y Avg-66.6%-1.1%-3.4%-22.7%-10.7%-3.1%-7.0%
Op Mgn LTM0.1%18.2%20.6%8.5%19.2%25.4%18.7%
Op Mgn 3Y Avg-1.6%17.8%20.9%10.5%20.2%27.1%19.0%
QoQ Delta Op Mgn LTM3.8%-0.2%-0.7%-0.3%0.1%-1.2%-0.2%
CFO/Rev LTM7.8%17.5%19.8%20.6%26.0%20.6%20.2%
CFO/Rev 3Y Avg7.3%19.1%25.0%17.5%27.2%22.3%20.7%
FCF/Rev LTM5.6%14.1%14.1%14.5%21.4%17.1%14.3%
FCF/Rev 3Y Avg4.7%15.7%19.5%11.0%21.8%17.7%16.7%

Valuation

HBIOTMOABIODHRWATMedian
NameHarvard .Thermo F.Agilent .Bio-Rad .Danaher Waters  
Mkt Cap0.3192.234.18.1130.319.927.0
P/S3.44.34.83.15.36.34.6
P/Op Inc2,984.023.723.437.127.424.826.1
P/EBIT-5.722.022.17.828.424.222.1
P/E-5.328.726.410.735.331.027.6
P/CFO44.324.624.415.220.230.524.5
Total Yield-19.0%3.5%4.6%9.4%2.8%3.2%3.4%
Dividend Yield0.0%0.0%0.8%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg1.6%3.3%3.4%3.3%3.4%2.5%3.3%
D/E0.10.20.10.20.10.10.1
Net D/E0.10.20.0-0.00.10.00.1

Returns

HBIOTMOABIODHRWATMedian
NameHarvard .Thermo F.Agilent .Bio-Rad .Danaher Waters  
1M Rtn25.3%7.5%7.8%13.5%-3.1%10.8%9.3%
3M Rtn12.9%-19.1%-13.6%-3.5%-23.8%-15.7%-14.7%
6M Rtn67.9%-9.2%-17.1%-9.9%-15.3%-4.1%-9.6%
12M Rtn70.1%18.7%18.1%22.8%-3.5%1.1%18.4%
3Y Rtn-86.3%-9.3%-11.0%-35.6%-16.7%9.0%-13.9%
1M Excs Rtn16.8%-1.0%-0.7%5.0%-11.6%2.3%0.8%
3M Excs Rtn9.1%-23.0%-17.4%-7.3%-27.6%-19.5%-18.5%
6M Excs Rtn62.1%-11.3%-21.4%-12.5%-17.4%-8.5%-11.9%
12M Excs Rtn45.3%-16.1%-17.2%-11.4%-38.2%-32.6%-16.7%
3Y Excs Rtn-158.4%-83.8%-84.0%-109.5%-89.6%-63.9%-86.8%

Comparison Analyses

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Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
Design, development, production and distribution of products and services that enable fundamental94112   
Instruments, equipment, software and accessories  10811497
Service, maintenance and warranty contracts  555
Total94112113119102


Net Income by Segment
$ Mil20252024202320222021
Design, development, production and distribution of products and services that enable fundamental-12-3   
Total-12-3   


Price Behavior

Price Behavior
Market Price$6.69 
Market Cap ($ Bil)0.3 
First Trading Date03/19/2001 
Distance from 52W High-15.0% 
   50 Days200 Days
DMA Price$5.48$5.45
DMA Trendupdown
Distance from DMA22.1%22.8%
 3M1YR
Volatility99.7%175.2%
Downside Capture0.011.07
Upside Capture105.87234.88
Correlation (SPY)18.2%13.9%
HBIO Betas & Captures as of 3/31/2026

 1M2M3M6M1Y3Y
Beta0.981.511.401.102.411.79
Up Beta3.911.962.572.522.172.04
Down Beta4.152.590.910.472.331.81
Up Capture-218%124%97%152%458%85%
Bmk +ve Days7162765139424
Stock +ve Days7172555105322
Down Capture81%104%173%96%164%112%
Bmk -ve Days12233358110323
Stock -ve Days14243770145400

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with HBIO
HBIO84.1%175.0%0.95-
Sector ETF (XLV)12.0%15.9%0.5213.8%
Equity (SPY)26.7%12.5%1.7714.1%
Gold (GLD)38.9%27.4%1.191.8%
Commodities (DBC)23.5%16.2%1.32-1.7%
Real Estate (VNQ)15.6%13.6%0.8216.4%
Bitcoin (BTCUSD)-12.8%42.6%-0.211.9%

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Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with HBIO
HBIO-37.1%95.3%-0.14-
Sector ETF (XLV)5.6%14.6%0.2020.3%
Equity (SPY)10.5%17.1%0.4824.5%
Gold (GLD)21.5%17.8%0.995.5%
Commodities (DBC)10.7%18.8%0.475.1%
Real Estate (VNQ)3.6%18.8%0.0920.8%
Bitcoin (BTCUSD)3.8%56.4%0.298.6%

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Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with HBIO
HBIO-13.4%79.5%0.12-
Sector ETF (XLV)9.5%16.5%0.4620.4%
Equity (SPY)13.8%17.9%0.6624.5%
Gold (GLD)13.9%15.9%0.735.5%
Commodities (DBC)8.1%17.6%0.389.2%
Real Estate (VNQ)5.4%20.7%0.2320.1%
Bitcoin (BTCUSD)68.1%66.9%1.077.1%

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Short Interest

Short Interest: As Of Date3312026
Short Interest: Shares Quantity0.1 Mil
Short Interest: % Change Since 3152026-82.1%
Average Daily Volume0.1 Mil
Days-to-Cover Short Interest1.3 days
Basic Shares Quantity44.6 Mil
Short % of Basic Shares0.2%

Earnings Returns History

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 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
2/10/202613.4%12.5%-4.3%
11/6/2025-7.3%5.7%28.6%
8/11/2025-9.2%0.2%-17.1%
3/12/2025-10.1%-11.6%-39.8%
11/7/2024-15.2%-23.0%-19.9%
8/8/202411.8%0.7%-2.9%
3/7/20249.7%6.8%10.0%
11/7/2023-1.2%-4.9%10.9%
...
SUMMARY STATS   
# Positive91210
# Negative968
Median Positive8.2%6.2%12.5%
Median Negative-7.3%-11.5%-12.3%
Max Positive14.7%53.6%71.8%
Max Negative-15.2%-23.0%-39.8%

SEC Filings

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Report DateFiling DateFiling
12/31/202503/13/202610-K
09/30/202511/06/202510-Q
06/30/202508/11/202510-Q
03/31/202505/12/202510-Q
12/31/202403/14/202510-K
09/30/202411/08/202410-Q
06/30/202408/08/202410-Q
03/31/202405/07/202410-Q
12/31/202303/07/202410-K
09/30/202311/07/202310-Q
06/30/202308/08/202310-Q
03/31/202304/26/202310-Q
12/31/202203/09/202310-K
09/30/202211/09/202210-Q
06/30/202208/04/202210-Q
03/31/202205/04/202210-Q

Recent Forward Guidance [BETA]

Latest: Q4 2025 Earnings Reported 3/12/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
Q1 2026 Revenue20.00 Mil21.00 Mil22.00 Mil   
Q1 2026 Adjusted Gross Margin57.0%58.0%59.0%   
Q1 2026 Adjusted EBITDA1.00 Mil1.60 Mil2.20 Mil   
2026 Revenue Growth2.0%3.0%4.0%   
2026 Adjusted Gross Margin58.0%59.0%60.0%   
2026 Adjusted EBITDA Growth6.0%8.0%10.0%   

Prior: Q3 2025 Earnings Reported 11/6/2025

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
Q4 2025 Revenue22.50 Mil23.50 Mil24.50 Mil17.5% Higher NewGuidance: 20.00 Mil for Q3 2025
Q4 2025 Gross Margin58.0%59.0%60.0%3.5%2.0%Higher NewGuidance: 57.0% for Q3 2025