Tearsheet

CryoPort (CYRX)


Market Price (5/21/2026): $14.2 | Market Cap: $708.5 Mil
Sector: Industrials | Industry: Air Freight & Logistics

CryoPort (CYRX)


Market Price (5/21/2026): $14.2
Market Cap: $708.5 Mil
Sector: Industrials
Industry: Air Freight & Logistics

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Attractive yield
Total YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 11%, ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is 6.8%

Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -25%

Megatrend and thematic drivers
Megatrends include Advanced Biologics Supply Chain. Themes include Cell and Gene Therapy Logistics, Cryogenic Cold Chain Management, and Biopharmaceutical Clinical Trial Support.

Trading close to highs
Dist 52W High is 0.0%

Weak multi-year price returns
2Y Excs Rtn is -40%, 3Y Excs Rtn is -111%

Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -39 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -21%

Stock price has recently run up significantly
12M Rtn12 month market price return is 109%

Weak revenue growth
Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -5.4%

Not cash flow generative
FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -14%

Key risks
CYRX key risks include [1] severe financial underperformance, Show more.

0 Attractive yield
Total YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 11%, ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is 6.8%
1 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -25%
2 Megatrend and thematic drivers
Megatrends include Advanced Biologics Supply Chain. Themes include Cell and Gene Therapy Logistics, Cryogenic Cold Chain Management, and Biopharmaceutical Clinical Trial Support.
3 Trading close to highs
Dist 52W High is 0.0%
4 Weak multi-year price returns
2Y Excs Rtn is -40%, 3Y Excs Rtn is -111%
5 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -39 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -21%
6 Stock price has recently run up significantly
12M Rtn12 month market price return is 109%
7 Weak revenue growth
Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -5.4%
8 Not cash flow generative
FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -14%
9 Key risks
CYRX key risks include [1] severe financial underperformance, Show more.

Valuation, Metrics & Events

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

CryoPort (CYRX) stock has gained about 50% since 1/31/2026 because of the following key factors:

1. CryoPort reported stronger-than-expected first-quarter 2026 financial results and raised its full-year revenue guidance.

The company announced Q1 2026 revenue of $47.8 million, representing a 16% year-over-year increase, surpassing analyst estimates of approximately $44.87 million. Management subsequently raised its full-year 2026 revenue guidance to between $192 million and $196 million, an increase from the previous guidance of $190 million to $194 million. Additionally, CryoPort anticipates achieving positive adjusted EBITDA in the second half of 2026, with Q1 2026 adjusted EBITDA from continuing operations improving to negative $0.6 million from negative $2.8 million in Q1 2025.

2. The company demonstrated significant growth in its support for commercial cell and gene therapies (CGT) and an expanding clinical trial pipeline.

Commercial CGT revenue surged by 26% year-over-year to $9.1 million in the first quarter of 2026. As of March 31, 2026, CryoPort supported a record 766 global clinical trials, including 91 in Phase III, and 21 commercially approved CGTs, indicating its deepening involvement in the high-growth regenerative medicine sector.

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Stock Movement Drivers

Fundamental Drivers

The 47.9% change in CYRX stock from 1/31/2026 to 5/20/2026 was primarily driven by a 30.9% change in the company's P/E Multiple.
(LTM values as of)13120265202026Change
Stock Price ($)9.5114.0747.9%
Change Contribution By: 
Total Revenues ($ Mil)1721836.2%
Net Income Margin (%)39.2%41.6%5.9%
P/E Multiple7.19.230.9%
Shares Outstanding (Mil)50500.5%
Cumulative Contribution47.9%

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2026 to 5/20/2026
ReturnCorrelation
CYRX47.9% 
Market (SPY)7.4%53.3%
Sector (XLI)3.5%35.2%

Fundamental Drivers

The 52.3% change in CYRX stock from 10/31/2025 to 5/20/2026 was primarily driven by a 49.7% change in the company's P/E Multiple.
(LTM values as of)103120255202026Change
Stock Price ($)9.2414.0752.3%
Change Contribution By: 
Total Revenues ($ Mil)16618310.0%
Net Income Margin (%)45.3%41.6%-8.2%
P/E Multiple6.29.249.7%
Shares Outstanding (Mil)50500.7%
Cumulative Contribution52.3%

LTM = Last Twelve Months as of date shown

Market Drivers

10/31/2025 to 5/20/2026
ReturnCorrelation
CYRX52.3% 
Market (SPY)9.3%47.1%
Sector (XLI)10.8%30.2%

Fundamental Drivers

The 152.2% change in CYRX stock from 4/30/2025 to 5/20/2026 was primarily driven by a 117.3% change in the company's P/S Multiple.
(LTM values as of)43020255202026Change
Stock Price ($)5.5814.07152.2%
Change Contribution By: 
Total Revenues ($ Mil)15718316.7%
P/S Multiple1.83.8117.3%
Shares Outstanding (Mil)5050-0.6%
Cumulative Contribution152.2%

LTM = Last Twelve Months as of date shown

Market Drivers

4/30/2025 to 5/20/2026
ReturnCorrelation
CYRX152.2% 
Market (SPY)35.2%33.7%
Sector (XLI)31.9%29.8%

Fundamental Drivers

The -33.1% change in CYRX stock from 4/30/2023 to 5/20/2026 was primarily driven by a -22.9% change in the company's Total Revenues ($ Mil).
(LTM values as of)43020235202026Change
Stock Price ($)21.0414.07-33.1%
Change Contribution By: 
Total Revenues ($ Mil)237183-22.9%
P/S Multiple4.33.8-10.8%
Shares Outstanding (Mil)4950-2.8%
Cumulative Contribution-33.1%

LTM = Last Twelve Months as of date shown

Market Drivers

4/30/2023 to 5/20/2026
ReturnCorrelation
CYRX-33.1% 
Market (SPY)85.2%32.3%
Sector (XLI)78.5%32.7%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
CYRX Return35%-71%-11%-50%23%36%-70%
Peers Return33%-35%4%11%-1%-22%-23%
S&P 500 Return27%-19%24%23%16%7%96%

Monthly Win Rates [3]
CYRX Win Rate50%42%33%50%50%40% 
Peers Win Rate58%37%50%45%53%32% 
S&P 500 Win Rate75%42%67%75%67%60% 

Max Drawdowns [4]
CYRX Max Drawdown-41%-73%-65%-71%-47%-31% 
Peers Max Drawdown-28%-53%-43%-32%-40%-33% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: AZTA, BLFS, TMO, GTLS, RGEN. See CYRX Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 5/20/2026 (YTD)

How Low Can It Go

EventCYRXS&P 500
2025 US Tariff Shock
  % Loss-31.8%-18.8%
  % Gain to Breakeven46.6%23.1%
  Time to Breakeven2 days79 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-42.6%-9.5%
  % Gain to Breakeven74.3%10.5%
  Time to Breakeven47 days24 days
2020 COVID-19 Crash
  % Loss-27.8%-33.7%
  % Gain to Breakeven38.5%50.9%
  Time to Breakeven43 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-34.9%-19.2%
  % Gain to Breakeven53.6%23.8%
  Time to Breakeven65 days105 days
2015-2016 China Devaluation / Global Growth Scare
  % Loss-62.9%-12.2%
  % Gain to Breakeven169.2%13.9%
  Time to Breakeven72 days62 days
2014-2016 Oil Price Collapse
  % Loss-52.6%-6.8%
  % Gain to Breakeven111.1%7.3%
  Time to Breakeven64 days15 days

Compare to AZTA, BLFS, TMO, GTLS, RGEN

In The Past

CryoPort's stock fell -31.8% during the 2025 US Tariff Shock. Such a loss loss requires a 46.6% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventCYRXS&P 500
2025 US Tariff Shock
  % Loss-31.8%-18.8%
  % Gain to Breakeven46.6%23.1%
  Time to Breakeven2 days79 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-42.6%-9.5%
  % Gain to Breakeven74.3%10.5%
  Time to Breakeven47 days24 days
2020 COVID-19 Crash
  % Loss-27.8%-33.7%
  % Gain to Breakeven38.5%50.9%
  Time to Breakeven43 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-34.9%-19.2%
  % Gain to Breakeven53.6%23.8%
  Time to Breakeven65 days105 days
2015-2016 China Devaluation / Global Growth Scare
  % Loss-62.9%-12.2%
  % Gain to Breakeven169.2%13.9%
  Time to Breakeven72 days62 days
2014-2016 Oil Price Collapse
  % Loss-52.6%-6.8%
  % Gain to Breakeven111.1%7.3%
  Time to Breakeven64 days15 days
2013 Taper Tantrum
  % Loss-63.5%-0.2%
  % Gain to Breakeven174.3%0.2%
  Time to Breakeven134 days1 days
2011 US Debt Ceiling Crisis & European Contagion
  % Loss-33.8%-17.9%
  % Gain to Breakeven51.0%21.8%
  Time to Breakeven1376 days123 days
2010 Eurozone Sovereign Debt Crisis / Flash Crash
  % Loss-51.1%-15.4%
  % Gain to Breakeven104.4%18.2%
  Time to Breakeven1829 days125 days
2008-2009 Global Financial Crisis
  % Loss-73.6%-53.4%
  % Gain to Breakeven278.8%114.4%
  Time to Breakeven371 days1085 days

Compare to AZTA, BLFS, TMO, GTLS, RGEN

In The Past

CryoPort's stock fell -31.8% during the 2025 US Tariff Shock. Such a loss loss requires a 46.6% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About CryoPort (CYRX)

Cryoport, Inc., a life sciences services company, provides temperature-controlled logistics solutions in the Americas, Europe, the Middle East, Africa, and the Asia Pacific. The company offers Cryoportal, a cloud-based logistics management platform that supports the management of shipments, which includes order entry, document preparation, customs documentation, courier management, real-time shipment tracking and monitoring, issue resolution, and regulatory compliance requirements; and CryoPort Express Shippers, which is used to ensure that the stability of shipped biologic commodities is maintained throughout the shipping cycle. It also provides information dashboards and validation documentation for shipments through data collected by the SmartPak Condition Monitoring System; and vacuum insulated aluminum dewars and cryogenic freezers systems. In addition, the company offers biological specimen cryopreservation storage and maintenance; archiving, monitoring, tracking, receipt, and delivery of samples; transportation of frozen biological specimens to and from customer locations; and management of incoming and outgoing biological specimens, as well as provides logistics support and management; and short-term logistics and engineering consulting services. It serves biopharma/pharma, animal health, and human reproductive medicine markets. The company was founded in 1999 and is headquartered in Brentwood, Tennessee.

AI Analysis | Feedback

Here are 1-3 brief analogies for CryoPort (CYRX):

  • Like a highly specialized FedEx or UPS, but exclusively for critical, temperature-sensitive biological materials.
  • An Iron Mountain for frozen biological samples, coupled with a global, specialized delivery network.

AI Analysis | Feedback

  • Cryoportal Platform: A cloud-based logistics management platform for order entry, documentation, real-time shipment tracking, and regulatory compliance.
  • Temperature-Controlled Shipping Solutions: Specialized shipping containers like CryoPort Express Shippers, vacuum insulated dewars, and cryogenic freezer systems to maintain biologic stability during transport.
  • Biospecimen Storage & Management: Services for the cryopreservation, archiving, monitoring, and transportation of biological specimens.
  • Logistics & Engineering Consulting: Short-term consulting engagements providing logistics support and engineering expertise.

AI Analysis | Feedback

CryoPort (CYRX) primarily sells its services and solutions to other companies within specific life sciences markets.

Based on the provided background, the company serves customers in the following categories:

  • Biopharma/Pharma Market
  • Animal Health Market
  • Human Reproductive Medicine Market

The background information does not provide the names of specific customer companies.

AI Analysis | Feedback

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Jerrell W. Shelton President and Chief Executive Officer, Cryoport, Inc.

Jerrell Shelton has over 40 years of executive and corporate governance experience across various industries including information services, software, telecommunications, manufacturing, natural resources, and distribution. He joined Cryoport's board in October 2012 and was appointed President and CEO in November 2012, becoming Chairman in October 2015. Previously, he was a visiting executive at IBM Research, where his team developed WebFountain. He also served as President and CEO of NDC Holdings, Continental Graphics Holdings, Thomson Business Information Group, and Advantage Companies, under his leadership each of those companies achieved rapid revenue growth, improved profitability, and increased shareholder value.

Robert S. Stefanovich Chief Financial Officer and Treasurer, Cryoport, Inc.

Robert Stefanovich has over 30 years of experience in financial management and strategy, with more than 20 years as CFO in the specialty pharma, medical device, and software industries. He previously served as CFO of Novalar Pharmaceuticals, a venture-backed specialty pharmaceutical company. He also held CFO positions at three publicly traded companies: Xcorporeal, Artemis International Solutions Corporation, and Aethlon Medical. Earlier in his career, he was Vice President of Administration at SAIC, a Fortune 500 company, and an audit manager with Price Waterhouse LLP’s technology practice.

Mark W. Sawicki, Ph. D. Chief Scientific Officer, Cryoport, Inc.

Mark Sawicki brings over 20 years of executive and sales management experience, consistently achieving corporate revenue and market share goals in the pharmaceutical and biotechnology industries. He most recently served as the chief business officer at Alcami. Prior to that, he held senior business development roles at AGC Biologics and Curia, where he significantly increased revenue.

Tony Ippolito Vice President, General Counsel and Corporate Secretary, Cryoport, Inc.

Tony Ippolito has over 18 years of experience in mergers and acquisitions, securities law, and general corporate law. Before joining Cryoport, he was a partner in the Corporate and Securities practice group at Snell & Wilmer, LLP, where his practice focused on advising reporting companies in securities law matters, mergers and acquisitions, private placements, and venture capital financings. He is also a former CPA and was a forensic accountant at FTI Consulting, Inc.

Phil Wilson Senior Vice President & Chief Operating Officer, Cryoport Systems

Phil Wilson is an accomplished supply chain executive with over 25 years of industry experience. Before joining Cryoport, he served as Vice President, Supply Chain for Ancillare LP. Prior to that, he was the Director of Global Operational Programs at Catalent Pharma Solutions, where he managed various aspects of the pharmaceutical supply chain.

AI Analysis | Feedback

The key risks to Cryoport's business (CYRX) are:

  1. Dependence on successful commercialization of cell and gene therapies: Cryoport's revenue growth is heavily reliant on the successful progression of its clients' cell and gene therapies through clinical trials and subsequent commercialization, including Biologics License Application (BLA) and Marketing Authorisation Application (MAA) approvals. Any slowdown in clinical trial activity, delays in regulatory approvals, or lower-than-anticipated commercial adoption of these advanced therapies could significantly impact Cryoport's growth trajectory. The company currently holds a substantial market share in the logistics for cell and gene therapy clinical trials, making its performance closely tied to the success rates within this niche but high-growth sector.
  2. Intense competition from larger logistics providers: While Cryoport has established a strong position in the specialized and complex logistics for cell and gene therapies, it faces increasing competition, particularly as the industry evolves towards larger-scale commercial distribution, such as for allogeneic therapies. This shift brings Cryoport into direct competition with global logistics giants like DHL, UPS, and FedEx, which possess extensive global networks, greater economies of scale, and the ability to offer competitive pricing or bundled services. Cryoport's more limited presence in the high-volume commercial distribution of mainstream pharmaceuticals, a segment dominated by these larger players, also highlights a competitive weakness.
  3. Ongoing unprofitability and high financial leverage: Cryoport has consistently reported ongoing losses and negative operating margins, indicating persistent challenges in achieving profitability. While the company has shown improvements in gross margins and narrowed adjusted EBITDA losses, it is not forecasted to become profitable within the next three years. Furthermore, Cryoport carries significant financial leverage, with its net debt/EBITDA ratio notably higher than the market average, and faces a convertible debt maturity in December 2026 which will require refinancing or repayment, potentially straining its cash reserves. The company's Altman Z-Score also suggests a potential risk of financial distress.

AI Analysis | Feedback

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AI Analysis | Feedback

CryoPort (NASDAQ: CYRX) operates within several addressable markets related to temperature-controlled logistics and cryopreservation for the life sciences industry.

  • Life Science Logistics Market (Global): The global life science logistics market was calculated at approximately USD 127.7 billion in 2024 and is projected to reach around USD 262.51 billion by 2034, expanding at a Compound Annual Growth Rate (CAGR) of 7.46% between 2025 and 2034. Another estimate values the global life science logistics market at USD 123.75 billion in 2024, with a projection to grow to USD 289.35 billion by 2035 at a CAGR of 8.03% during the forecast period of 2025–2035. A different source indicates the global life science logistics market size at USD 17.69 billion in 2024, predicted to increase to approximately USD 38.19 billion by 2034, growing at a CAGR of 8.00% from 2025 to 2034.

  • Pharmaceutical Cold Chain Logistics Market (Global): This market was valued at approximately USD 27.9 billion in 2024 and is forecast to reach nearly USD 49.6 billion by 2032, with a CAGR of about 8.5%.

  • Cell and Gene Therapy Cold-Chain Logistics Market (Global): This specialized sector is estimated at USD 1.9 billion in 2024 and is projected to exceed USD 8 billion by 2034, demonstrating a CAGR of about 15.6%. The cell and gene therapy logistics sector is also projected to reach USD 37.8 billion by 2027. The commercial cell and gene therapy (CGT) market is expected to grow from USD 10 billion in 2025 to USD 38 billion by 2030, at a CAGR of approximately 30%. In North America, this market represents roughly 44% of the global total.

  • Cell Cryopreservation Market (Global): The global cell cryopreservation market size is estimated at USD 3.30 billion in 2025 and is projected to reach USD 8.68 billion by 2034, growing at a CAGR of 11.37%. Another report estimates the global cell cryopreservation market size at USD 3.38 billion in 2024, projected to reach USD 8.86 billion by 2033, with a CAGR of 11.40% from 2025 to 2033. A more optimistic projection values the global cell cryopreservation market at USD 11.19 billion in 2024, expected to reach USD 50.88 billion by 2032, growing at a robust CAGR of 21.0%. North America held the largest share of 40.46% of the global market in 2024.

  • Cryopreservation Services Market (Global): This market was estimated to be worth USD 8 billion in 2023 and is expected to increase to USD 34.07 billion by 2030, with a projected CAGR of 23% from 2024 to 2030.

  • Cryopreservation Systems Market (Global): This market, which includes cryogenic vessels and freezers, is estimated at USD 3.9 billion in 2025 and is projected to reach USD 7.1 billion by 2035, growing at a CAGR of 6.2% over the forecast period. The USA market specifically is estimated at USD 1.4 billion in 2025 and is anticipated to reach USD 2.3 billion by 2035.

AI Analysis | Feedback

CryoPort (NASDAQ: CYRX) is positioned for future revenue growth over the next 2-3 years, driven by several key factors:

  1. Growth in Commercial Cell and Gene Therapy (CGT) Support: CryoPort has demonstrated robust double-digit revenue growth from its commercial cell and gene therapy support services, with a 29% increase year-over-year in 2025. This segment is expected to continue expanding as more advanced therapies gain market acceptance.
  2. Conversion of Clinical Trials to Commercial Therapies: The company supports a significant number of clinical trials globally, including 86 in Phase 3 and 361 in Phase 2 as of December 31, 2025. This extensive pipeline represents a substantial foundation for future commercial cell and gene therapy revenue streams as these trials progress toward regulatory approval and commercialization.
  3. Expansion of Global Footprint and Network: CryoPort is strategically expanding its global supply chain network by adding regional depots and biorepositories, including new facilities in Paris, France, and Santa Ana, California. Additionally, strategic partnerships, such as the collaboration with DHL Group, are expected to enhance CryoPort's reach and service capabilities in global growth markets like EMEA and APAC.
  4. Launch of New Products and Services: The continuous introduction of new products and service enhancements contributes to revenue growth. Recent innovations include the Cryoport Express® Cryogenic HV3 Shipping System, designed to improve patient accessibility and shipping efficiency, and other new offerings like the Fusion® 800 Series cryogenic freezer and IntegriCell™ cryopreservation services.
  5. Growth in BioStorage and BioServices: The BioStorage and BioServices segment has shown strong momentum, with revenue growing 22% annually in 2025. This area is a key component of the Life Sciences Services business and is anticipated to continue its upward trajectory as demand for specialized biological specimen storage and maintenance increases.

AI Analysis | Feedback

Here is a summary of Cryoport's capital allocation decisions over the last 3-5 years:

Share Repurchases

  • Cryoport initiated a buyback program on August 1, 2024, authorizing the repurchase of up to $200 million of its common stock and/or convertible senior notes through the end of 2027.
  • Under this program, the company agreed to repurchase approximately $160 million in aggregate principal amount of its 0.75% Convertible Senior Notes due in 2026 for an aggregate repurchase price of $141.6 million, plus accrued interest, at an 11.5% discount.
  • As of December 2, 2025, Cryoport had approximately $65.9 million remaining under its share repurchase authorization.

Outbound Investments

  • In 2025, Cryoport divested its CRYOPDP specialty courier business to DHL Group. This divestiture resulted in a net income of $112.3 million from discontinued operations for the fiscal year 2025.

Capital Expenditures

  • Cryoport's capital expenditures were $24 million in 2022, $44 million in 2023, and $20 million in 2024.
  • The company's capital spending on property, plant, and equipment was $3.45 million in Q4 2025.
  • In 2025, Cryoport increased investments into Cryoport Systems to support cell and gene therapy clients. These investments include the launch of a Global Supply Chain Center in Paris, France, the expansion of its Belgian operations, and the consolidation of three facilities in Irvine, California, into one expansive Global Supply Chain Center in Santa Ana, California.

Better Bets vs. CryoPort (CYRX)

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Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

CYRXAZTABLFSTMOGTLSRGENMedian
NameCryoPort Azenta BioLife .Thermo F.Chart In.Repligen  
Mkt Price14.0718.5724.00451.79207.49111.7467.87
Mkt Cap0.70.91.2168.19.96.33.7
Rev LTM18359610045,1964,147763680
Op Inc LTM-39-20-158,2075255218
FCF LTM-2629-26,7481010419
FCF 3Y Avg-3732-37,01113611071
CFO LTM-161188,28710513183
CFO 3Y Avg-86768,451249141104

Growth & Margins

CYRXAZTABLFSTMOGTLSRGENMedian
NameCryoPort Azenta BioLife .Thermo F.Chart In.Repligen  
Rev Chg LTM14.0%1.7%27.5%5.4%-1.5%17.4%9.7%
Rev Chg 3Y Avg-5.4%0.8%12.6%1.1%40.3%1.3%1.2%
Rev Chg Q16.5%1.0%24.7%6.2%-11.7%14.8%10.5%
QoQ Delta Rev Chg LTM3.8%0.2%5.8%1.4%-2.7%3.4%2.4%
Op Inc Chg LTM17.5%37.2%-813.6%4.7%-23.6%292.7%11.1%
Op Inc Chg 3Y Avg-11.7%33.0%-248.5%3.7%68.5%-123.9%-4.0%
Op Mgn LTM-21.4%-3.3%-15.4%18.2%12.7%6.8%1.8%
Op Mgn 3Y Avg-30.6%-5.1%-14.5%17.9%13.8%1.2%-1.9%
QoQ Delta Op Mgn LTM-0.6%-0.1%1.4%-0.0%-2.0%1.0%-0.1%
CFO/Rev LTM-0.3%10.2%17.9%18.3%2.5%17.1%13.7%
CFO/Rev 3Y Avg-5.3%11.9%3.9%19.4%6.0%21.1%9.0%
FCF/Rev LTM-14.3%4.8%-1.8%14.9%0.2%13.7%2.5%
FCF/Rev 3Y Avg-23.4%5.8%-6.1%16.1%3.2%16.4%4.5%

Valuation

CYRXAZTABLFSTMOGTLSRGENMedian
NameCryoPort Azenta BioLife .Thermo F.Chart In.Repligen  
Mkt Cap0.70.91.2168.19.96.33.7
P/S3.81.411.73.72.48.23.8
P/Op Inc-17.9-43.7-75.720.518.9120.50.5
P/EBIT-21.4-43.7-75.718.945.680.7-1.3
P/E9.2-4.8-392.824.5-383.3122.52.2
P/CFO-1,395.814.065.020.394.848.234.2
Total Yield10.8%-20.8%-0.3%4.1%-0.3%0.8%0.3%
Dividend Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg-8.1%2.1%-0.4%3.6%2.1%1.4%1.8%
D/E0.30.10.00.30.40.10.2
Net D/E-0.2-0.4-0.10.20.4-0.0-0.0

Returns

CYRXAZTABLFSTMOGTLSRGENMedian
NameCryoPort Azenta BioLife .Thermo F.Chart In.Repligen  
1M Rtn32.9%-29.7%8.2%-14.1%-0.3%-15.3%-7.2%
3M Rtn64.4%-37.7%5.1%-11.9%0.1%-19.1%-5.9%
6M Rtn66.3%-38.2%-1.6%-21.1%1.8%-27.9%-11.3%
12M Rtn108.8%-34.3%5.2%9.6%24.2%-12.4%7.4%
3Y Rtn-30.2%-56.4%12.1%-13.5%79.8%-29.8%-21.7%
1M Excs Rtn26.5%-34.6%2.1%-19.1%-5.4%-21.0%-12.3%
3M Excs Rtn54.0%-45.7%-5.0%-20.5%-8.1%-26.9%-14.3%
6M Excs Rtn53.9%-48.2%-11.4%-31.6%-9.5%-36.4%-21.5%
12M Excs Rtn89.2%-56.2%-20.0%-15.1%-2.5%-36.1%-17.6%
3Y Excs Rtn-111.1%-134.0%-56.4%-92.6%0.0%-107.2%-99.9%

Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
Life Sciences Services8615013411955
Life Sciences Products728910310423
Elimination of intersegment revenue-1-6   
Total15723323722379


Price Behavior

Price Behavior
Market Price$14.07 
Market Cap ($ Bil)0.7 
First Trading Date02/23/2007 
Distance from 52W High0.0% 
   50 Days200 Days
DMA Price$10.14$9.51
DMA Trendupup
Distance from DMA38.8%48.0%
 3M1YR
Volatility59.1%68.5%
Downside Capture161.67166.54
Upside Capture298.89208.41
Correlation (SPY)50.3%34.0%
CYRX Betas & Captures as of 4/30/2026

 1M2M3M6M1Y3Y
Beta1.021.581.691.571.771.68
Up Beta0.460.530.571.461.631.62
Down Beta-0.112.412.491.642.001.71
Up Capture226%248%218%190%278%273%
Bmk +ve Days15223166141428
Stock +ve Days14243565121344
Down Capture89%136%176%140%137%112%
Bmk -ve Days4183056108321
Stock -ve Days8172756126401

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with CYRX
CYRX118.9%68.5%1.41-
Sector ETF (XLI)20.0%15.5%0.9828.2%
Equity (SPY)26.2%12.1%1.6234.3%
Gold (GLD)40.2%26.8%1.243.3%
Commodities (DBC)46.2%18.7%1.89-16.0%
Real Estate (VNQ)11.1%13.4%0.5424.4%
Bitcoin (BTCUSD)-27.4%41.8%-0.6520.7%

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Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with CYRX
CYRX-22.2%77.6%0.01-
Sector ETF (XLI)12.3%17.4%0.5537.8%
Equity (SPY)14.1%17.0%0.6542.2%
Gold (GLD)19.5%18.0%0.894.7%
Commodities (DBC)11.1%19.4%0.464.5%
Real Estate (VNQ)4.0%18.8%0.1138.3%
Bitcoin (BTCUSD)9.1%55.6%0.3721.2%

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Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with CYRX
CYRX22.2%73.7%0.61-
Sector ETF (XLI)13.8%20.0%0.6127.0%
Equity (SPY)15.5%17.9%0.7433.3%
Gold (GLD)13.1%16.0%0.684.4%
Commodities (DBC)7.9%17.9%0.365.9%
Real Estate (VNQ)5.4%20.7%0.2326.5%
Bitcoin (BTCUSD)67.1%66.9%1.0612.3%

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Short Interest

Short Interest: As Of Date4302026
Short Interest: Shares Quantity2.2 Mil
Short Interest: % Change Since 4152026-2.4%
Average Daily Volume0.4 Mil
Days-to-Cover Short Interest5.2 days
Basic Shares Quantity49.9 Mil
Short % of Basic Shares4.4%

Earnings Returns History

Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
3/3/20262.9%-7.2%0.2%
11/4/2025-7.5%-4.0%3.5%
8/6/2025-6.3%3.8%18.3%
3/4/202530.6%31.4%21.7%
11/7/2024-3.6%-8.0%3.9%
8/6/2024-0.3%5.3%5.4%
3/12/2024-11.9%1.5%10.8%
11/8/202310.0%29.5%48.3%
...
SUMMARY STATS   
# Positive101112
# Negative11109
Median Positive7.7%5.3%10.6%
Median Negative-3.6%-7.0%-6.4%
Max Positive30.6%39.4%54.9%
Max Negative-32.0%-24.1%-31.3%

SEC Filings

Expand for More
Report DateFiling DateFiling
03/31/202605/05/202610-Q
12/31/202503/05/202610-K
09/30/202511/06/202510-Q
06/30/202508/12/202510-Q
03/31/202505/08/202510-Q
12/31/202403/07/202510-K
09/30/202411/07/202410-Q
06/30/202408/08/202410-Q
03/31/202405/08/202410-Q
12/31/202303/13/202410-K
09/30/202311/09/202310-Q
06/30/202308/09/202310-Q
03/31/202305/04/202310-Q
12/31/202202/28/202310-K
09/30/202211/04/202210-Q
06/30/202208/04/202210-Q

Recent Forward Guidance [BETA]

Latest: Q1 2026 Earnings Reported 5/4/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2026 Revenue192.00 Mil194.00 Mil196.00 Mil1.0% RaisedGuidance: 192.00 Mil for 2026

Prior: Q4 2025 Earnings Reported 3/3/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2026 Revenue190.00 Mil192.00 Mil194.00 Mil11.6% Higher NewGuidance: 172.00 Mil for 2025

Insider Activity

Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Stefanovich, RobertChief Financial OfficerDirectSell32520268.181,0948,9492,284,486Form
2Shelton, JerrellPresident, CEODirectSell32520268.182,89423,6738,602,145Form
3Sawicki, Mark WChief Scientific OfficerDirectSell32520268.181,34110,969837,272Form
4Zecchini, Edward JSee RemarksDirectSell31720268.002,01416,112877,752Form
5Shelton, JerrellPresident, CEODirectSell31720268.007,91863,3448,436,008Form