Tearsheet

Cerus (CERS)


Market Price (12/4/2025): $1.99 | Market Cap: $381.7 Mil
Sector: Health Care | Industry: Life Sciences Tools & Services

Cerus (CERS)


Market Price (12/4/2025): $1.99
Market Cap: $381.7 Mil
Sector: Health Care
Industry: Life Sciences Tools & Services

Investment Highlights Why It Matters Which of these 2 stories sounds closer for this stock?

1. Generates cash flow

The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.

2. Riding a trend

Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow


0 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics. Themes include Blood Safety Technologies.
Weak multi-year price returns
2Y Excs Rtn is -39%, 3Y Excs Rtn is -119%
Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -9.5 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -4.8%
1   Expensive valuation multiples
P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 86x
2   Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -9.4%
0 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics. Themes include Blood Safety Technologies.
1 Weak multi-year price returns
2Y Excs Rtn is -39%, 3Y Excs Rtn is -119%
2 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -9.5 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -4.8%
3 Expensive valuation multiples
P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 86x
4 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -9.4%

Valuation, Metrics & Events

CERS Stock


Why The Stock Moved


Qualitative Assessment

AI Generated Analysis | Feedback

Cerus (CERS) stock experienced an approximate 51.9% increase from late August 2025 to early December 2025, primarily driven by several positive financial and operational developments.

1. Strong Third Quarter 2025 Financial Performance: Cerus reported a record-breaking third quarter for 2025, with total revenue increasing by 19% to $60.2 million and product revenue reaching $52.7 million, marking a 15% year-over-year growth. The company also surpassed analyst estimates, reporting $0.00 earnings per share (EPS), which was $0.03 better than the estimated loss of ($0.03), and revenue that exceeded the consensus estimate.

2. Raised Full-Year 2025 Revenue Guidance: Following robust performance, Cerus raised its full-year 2025 product revenue guidance for the second time, setting a new range of $202 million to $204 million. This reflected increased confidence in sustained momentum across its product franchises.

Show more

Stock Movement Drivers

Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
CERS Return64%-2%-46%-41%-29%21%-56%
Peers Return47%19%-8%2%-12%32%93%
S&P 500 Return16%27%-19%24%23%16%112%

Monthly Win Rates [3]
CERS Win Rate58%42%50%42%33%40% 
Peers Win Rate50%50%38%38%33%57% 
S&P 500 Win Rate58%75%42%67%75%70% 

Max Drawdowns [4]
CERS Max Drawdown-32%-31%-50%-66%-30%-25% 
Peers Max Drawdown-30%-8%-30%-24%-24%-16% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: A, TECH, ATEC, AVRT, BLLN.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 12/3/2025 (YTD)

How Low Can It Go

Unique KeyEventCERSS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-84.2%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven534.4%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-47.7%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven91.3%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven37 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-56.2%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven128.2%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven244 days120 days
2008 Global Financial Crisis2008 Global Financial Crisis  
2008 Global Financial Crisis% Loss% Loss-94.3%-56.8%
2008 Global Financial Crisis% Gain to Breakeven% Gain to Breakeven1655.2%131.3%
2008 Global Financial CrisisTime to BreakevenTime to BreakevenNot Fully Recovered days1480 days

Compare to A, TECH, ATEC, AVRT, BLLN


In The Past

Cerus's stock fell -84.2% during the 2022 Inflation Shock from a high on 11/4/2021. A -84.2% loss requires a 534.4% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth over time.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Cerus (CERS)

Better Bets than Cerus (CERS)

Latest Trefis Analyses

TitleTopic
0DASHBOARDS 
1Is Cerus Stock Built to Withstand a Pullback?Return
Title
0ARTICLES

Trade Ideas

Select past ideas related to CERS. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
4.1%4.1%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-9.8%-9.8%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
6.0%6.0%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
9.7%9.7%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
6.2%6.2%-5.1%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
4.1%4.1%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-9.8%-9.8%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
6.0%6.0%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
9.7%9.7%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
6.2%6.2%-5.1%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for Cerus

Peers to compare with:

Financials

CERSATECHATECAVRTBLLNMedian
NameCerus Agilent .Bio-Tech.Alphatec Avertix .BillionT. 
Mkt Price1.99149.2663.8221.23-102.7663.82
Mkt Cap0.442.49.93.2--6.6
Rev LTM1996,7881,217728--972
Op Inc LTM-91,444250-74--120
FCF LTM01,088224-3--112
FCF 3Y Avg-151,308228-112--106
CFO LTM41,49525135--143
CFO 3Y Avg-121,662271-36--130

Growth & Margins

CERSATECHATECAVRTBLLNMedian
NameCerus Agilent .Bio-Tech.Alphatec Avertix .BillionT. 
Rev Chg LTM13.0%4.5%3.9%27.1%--8.8%
Rev Chg 3Y Avg8.3%0.8%2.9%31.8%--5.6%
Rev Chg Q14.5%10.1%-1.0%30.4%--12.3%
QoQ Delta Rev Chg LTM3.5%2.4%-0.2%6.7%--2.9%
Op Mgn LTM-4.8%21.3%20.6%-10.1%--7.9%
Op Mgn 3Y Avg-11.9%21.5%21.9%-21.8%--4.8%
QoQ Delta Op Mgn LTM1.3%-0.1%0.7%3.8%--1.0%
CFO/Rev LTM1.8%22.0%20.6%4.8%--12.7%
CFO/Rev 3Y Avg-7.5%24.6%23.0%-7.6%--7.8%
FCF/Rev LTM0.1%16.0%18.4%-0.5%--8.1%
FCF/Rev 3Y Avg-9.7%19.4%19.4%-21.7%--4.8%

Valuation

CERSATECHATECAVRTBLLNMedian
NameCerus Agilent .Bio-Tech.Alphatec Avertix .BillionT. 
Mkt Cap0.442.49.93.2--6.6
P/S1.54.97.13.0--4.0
P/EBIT-42.122.274.8-19.2--1.5
P/E-19.127.5110.9-14.2--6.6
P/CFO85.522.434.462.8--48.6
Total Yield-5.2%4.5%1.5%-7.0%---1.9%
Dividend Yield0.0%0.8%0.6%0.0%--0.3%
FCF Yield 3Y Avg-5.1%3.7%2.2%-11.2%---1.5%
D/E0.30.10.00.3--0.2
Net D/E0.10.10.00.2--0.1

Returns

CERSATECHATECAVRTBLLNMedian
NameCerus Agilent .Bio-Tech.Alphatec Avertix .BillionT. 
1M Rtn30.9%3.2%4.3%10.1%--7.2%
3M Rtn51.9%19.4%19.8%33.5%--26.7%
6M Rtn38.2%30.4%28.4%72.9%--34.3%
12M Rtn12.4%8.0%-14.5%112.3%--10.2%
3Y Rtn-52.0%-2.0%-23.6%106.7%---12.8%
1M Excs Rtn31.0%3.2%4.4%10.1%--7.2%
3M Excs Rtn44.3%11.1%15.4%22.9%--19.2%
6M Excs Rtn23.5%15.7%13.7%58.2%--19.6%
12M Excs Rtn-6.0%-4.5%-28.4%89.0%---5.2%
3Y Excs Rtn-119.0%-72.6%-94.4%50.7%---83.5%

Financials

Segment Financials

Revenue by Segment

$ Mil20242023202220212020
Product revenue15616213111494
Total15616213111494


Price Behavior

Short Interest

Short Interest: As Of Date11142025
Short Interest: Shares Quantity5,720,796
Short Interest: % Change Since 103120259.6%
Average Daily Volume1,393,250
Days-to-Cover Short Interest4.11
Basic Shares Quantity191,830,000
Short % of Basic Shares3.0%

SEC Filings

Expand for More

Report DateFiling DateFiling
93020251106202510-Q 9/30/2025
6302025805202510-Q 6/30/2025
3312025501202510-Q 3/31/2025
12312024226202510-K 12/31/2024
93020241031202410-Q 9/30/2024
6302024801202410-Q 6/30/2024
3312024502202410-Q 3/31/2024
12312023305202410-K 12/31/2023
93020231102202310-Q 9/30/2023
6302023803202310-Q 6/30/2023
3312023504202310-Q 3/31/2023
12312022301202310-K 12/31/2022
93020221103202210-Q 9/30/2022
6302022804202210-Q 6/30/2022
3312022505202210-Q 3/31/2022
12312021222202210-K 12/31/2021