Tempus AI Stock: 5 Straight Green Days, Up 37%

TEMYTD+36.1%SPYYTD+12.1%XLVYTD+9.5%
Analyze TEM →

A five-day run has sharply repriced the stock, but the underlying numbers present a divided picture.

Shares of Tempus AI (TEM) have gained 36.8% over a winning streak that has now lasted for 5 consecutive trading days. That run has added about $3.9 billion to the company’s market value, which now stands at about $14.5 billion. The stock trades at about $80.36 a share as of 9/17/2026.

For anyone holding the stock, the move is a significant gain in a short period.

Image from Pixabay

How The Streak Stacks Up Against The S&P 500

Recent performance for TEM stock across the winning streak and prior periods:

Return Period TEM S&P 500
1D 14.8% 1.1%
5D (Current Streak) 36.8% 0.6%
1M (21D) 62.8% -0.7%
3M (63D) 64.7% 2.9%
YTD 2026 36.1% 11.6%
2025 74.9% 16.4%
2024 23.3%
2023 24.2%

Is This The Market’s Move, Or The Company’s?

This streak appears to be the stock’s own story. Over the same 5 trading days, the S&P 500 returned just +0.6%. The company’s fundamentals present a divided picture. Revenue over the last twelve months grew 50.4%, compared to an 8.1% median across large-cap Health Care companies in the S&P 500.

However, the company’s operating margin over the same period is -19.8%, compared to a median of 17.6% for S&P 500 Health Care stocks. Tempus AI also has negative trailing earnings, so it does not have a meaningful price-to-earnings multiple.

What Does A Streak Tell An Investor To Do?

A streak is not an instruction to buy or sell. It is simply information. It tells you that a stock has momentum and that other market participants are paying attention to it. The disciplined response is to use that information as a prompt to check your own thinking.

The core task is always the same: weigh the quality of the business against the price being asked for a share of it. A streak changes the price side of that equation, and the numbers here offer a starting point for re-evaluating the business side.

If you are hunting for strength that has more behind it than a hot tape, our Guidance Momentum screen surfaces the names where management raised its own outlook, which is the kind of momentum that tends to persist.

Those drawn to the strength but not the single-name risk have another route: our ETF Scorecard shows how the health care funds stack up. Any one of those funds is still a concentrated bet on that one theme, though, which is exactly the gap the portfolio below closes.

One Hot Stock Is A Story. Thirty Sound Ones Are A Strategy

A streak like this earns a place on your watchlist, and it also earns a question: how much of your outcome do you want depending on one company keeping this up?

The Trefis High Quality (HQ) Portfolio answers it with breadth: roughly 30 businesses picked for consistent cash generation, strong margins, and balance-sheet strength, sized and rebalanced by rules. It has a track record of outpacing a benchmark that combines the three major indices – the S&P 500, S&P Mid-cap, and Russell 2000. Follow the story; invest in the strategy.