Market Movers | Winners: SRZN, MNTK, CD | Losers: LRMR, ACAD, SGMT
A day of extreme moves in individual stocks unfolded against a backdrop of flat major indexes.
Surrozen (SRZN) gained +108.4% in a single session. The move came on a day when the S&P 500 returned 0.0% and the Dow Jones Industrial Average returned -0.3%. Such a large individual gain against a quiet tape raises a key question: are these moves just one-day noise, or do they signal something more persistent? The day’s biggest winners and losers are below.

Thursday’s Market Winners
The 10 US-listed stocks in the Trefis coverage universe with the highest returns on the last trading day:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | SRZN | Surrozen | 108.4% | 49.0% |
| 2 | MNTK | Montauk Renewables | 26.6% | 72.5% |
| 3 | CD | Chaince Digital | 20.8% | 4.0% |
| 4 | DNA | Ginkgo Bioworks | 19.5% | 23.3% |
| 5 | TWST | Twist Bioscience | 16.1% | 480.2% |
| 6 | GRAL | GRAIL | 15.4% | 46.3% |
| 7 | BALY | Ballys | 15.1% | -15.0% |
| 8 | QMCO | Quantum | 13.6% | 357.2% |
| 9 | CYPH | Cypherpunk Technologies | 13.0% | 251.7% |
| 10 | CDNA | CareDx | 13.0% | 225.7% |
Thursday’s Market Losers
And the 10 US-listed stocks in the Trefis coverage universe with the lowest returns:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | LRMR | Larimar Therapeutics | -14.1% | -12.9% |
| 2 | ACAD | ACADIA Pharmaceuticals | -12.8% | -17.0% |
| 3 | SGMT | Sagimet Biosciences | -12.6% | 53.9% |
| 4 | GEN | Gen Digital | -12.0% | -13.9% |
| 5 | GIL | Gildan Activewear | -12.0% | -34.1% |
| 6 | VKTX | Viking Therapeutics | -11.8% | 4.5% |
| 7 | KGC | Kinross Gold | -11.6% | -12.9% |
| 8 | MGM | MGM Resorts International | -11.0% | -7.7% |
| 9 | RCKT | Rocket Pharmaceuticals | -10.9% | -23.4% |
| 10 | FISN | Deep Fission | -10.9% | n/a |
Some of today’s moves reflect longer-term strength.
Montauk Renewables (MNTK) appears on both the one-day and one-month winners lists. Its +26.6% daily return is part of a one-month gain of +58.2%. The strength is not a one-day event, as it still gained +25.0% over the other sessions. Chaince Digital (CD) shows a similar pattern, with a +20.8% daily return contributing to a +56.0% one-month gain. Excluding today, it still gained +29.1%.
Movers Over The Last Week
Widening the window to five trading days, these are the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | SRZN | Surrozen | 98.8% | 49.0% |
| 2 | CD | Chaince Digital | 77.7% | 4.0% |
| 3 | GRAL | GRAIL | 56.6% | 46.3% |
| 4 | BALY | Ballys | 35.4% | -15.0% |
| 5 | FWDI | Forward Industries | 34.7% | 26.3% |
| 6 | CYPH | Cypherpunk Technologies | 32.9% | 251.7% |
| 7 | PRTH | Priority Technology | 30.9% | 42.9% |
| 8 | MNTK | Montauk Renewables | 30.9% | 72.5% |
| 9 | DNA | Ginkgo Bioworks | 30.7% | 23.3% |
| 10 | VICR | Vicor | 27.6% | 151.9% |
Losers
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | XENE | Xenon Pharmaceuticals | -33.6% | -15.1% |
| 2 | XNDU | Xanadu Quantum Technologies | -33.4% | n/a |
| 3 | CGEM | Cullinan Therapeutics | -27.7% | 49.2% |
| 4 | KDK | Kodiak AI | -27.4% | -74.5% |
| 5 | CTEV | Claritev | -26.4% | -45.4% |
| 6 | ALKT | Alkami Technology | -24.4% | -38.5% |
| 7 | GEN | Gen Digital | -23.6% | -13.9% |
| 8 | RCKT | Rocket Pharmaceuticals | -23.1% | -23.4% |
| 9 | RSI | Rush Street Interactive | -22.6% | 0.6% |
| 10 | BYND | Beyond Meat | -21.5% | -62.6% |
Movers Over The Last Month
And over the last 21 trading days, the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | INDP | Indaptus Therapeutics | 265.3% | 37.5% |
| 2 | CYPH | Cypherpunk Technologies | 148.8% | 251.7% |
| 3 | SVIA | Silvia | 76.0% | 12.2% |
| 4 | MNTK | Montauk Renewables | 58.2% | 72.5% |
| 5 | OKTA | OKTA | 58.2% | 139.0% |
| 6 | CD | Chaince Digital | 56.0% | 4.0% |
| 7 | TMS | Teamshares | 52.6% | n/a |
| 8 | GRAL | GRAIL | 51.7% | 46.3% |
| 9 | BALY | Ballys | 48.1% | -15.0% |
| 10 | SDGR | Schrodinger | 47.3% | 64.7% |
Losers
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | ALMS | Alumis | -69.6% | -25.3% |
| 2 | XNDU | Xanadu Quantum Technologies | -52.0% | n/a |
| 3 | RARE | Ultragenyx Pharmaceutical | -44.2% | -35.8% |
| 4 | ALHC | Alignment Healthcare | -43.6% | -61.2% |
| 5 | SWMR | Swarmer | -43.4% | n/a |
| 6 | IMUX | Immunic | -43.2% | 74.6% |
| 7 | FBYD | Falcons Beyond Global | -40.1% | -55.0% |
| 8 | GSHD | Goosehead Insurance | -39.7% | -40.7% |
| 9 | PRLD | Prelude Therapeutics | -39.5% | 37.6% |
| 10 | CTEV | Claritev | -37.9% | -45.4% |
A movers list is a starting point, not an instruction.
The tables earlier in this report show the largest percentage moves, which is information about attention and risk. A large gain or loss does not, by itself, suggest a stock is a good or bad investment. The disciplined follow-up for any name on these lists is to check the business behind the move. The list identifies where the market’s attention was sharpest; the work of deciding what that means begins from there.
Either side of these lists can be a lead worth following, with the same follow-up question: does the business back the move? For the winners, our Guidance Momentum screen tracks which companies raised their own forward numbers. For the losers, our Buy the Dip screen flags which marked-down names still have the fundamentals to recover.
Today’s Winner Is Tomorrow’s Loser Often Enough
The movers list is the most honest picture of single-stock risk the market prints each day: the same volatility that makes the winners column also fills the losers column, and no one reliably knows which side a stock lands on next.
That is the case for owning a disciplined basket instead of chasing the tape. The Trefis High Quality (HQ) Portfolio holds roughly 30 businesses selected for consistent cash generation, strong margins, and resilient balance sheets, sized and rebalanced with rules. It has a track record of outpacing a benchmark that combines the S&P 500, the S&P MidCap 400, and the Russell 2000. Watch the movers for information; let the portfolio do the compounding.