Market Movers | Winners: AEMD, HYFM, FUSE | Losers: GYGY, CALC, MIRA
A single stock’s explosive gain rewrites its monthly performance, raising questions about the nature of market momentum.
Aethlon Medical (AEMD) gained +403.0% in a single session, an extreme move that stands out even on a broadly positive day for the market. The major indices saw solid gains, with the S&P 500 returning +1.5%, the Dow Jones Industrial Average returning +1.3%, and the Nasdaq-100 returning +1.8%. But how should an investor process a move of that magnitude? The day’s biggest winners and losers are below.

Monday’s Market Winners
The 7 stocks with the highest returns on the last trading day:
- Where The Buying Ran Strongest: 19 S&P 500 Stocks At 52-Week Highs
- 57 Small Cap Stocks Just Made New 52-Week Highs
- Where The Buying Ran Strongest: 22 Mid Cap Stocks At 52-Week Highs
- The 52-Week-Low List: 7 Names On Monday
- 11 Large Cap Stocks Just Made New 52-Week Highs
- S&P 500 Movers | Winners: FSLR, COHR, LITE | Losers: MAR, FICO, EBAY
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | AEMD | Aethlon Medical | 403.0% | 20.4% |
| 2 | HYFM | Hydrofarm | 298.1% | 42.4% |
| 3 | FUSE | Fusemachines | 69.6% | -19.4% |
| 4 | EZRA | Reliance Global | 45.6% | n/a |
| 5 | ULH | Universal Logistics | 36.1% | 21.4% |
| 6 | LUNG | Pulmonx | 30.1% | -4.1% |
| 7 | SDST | Stardust Power | 29.6% | -77.1% |
Monday’s Market Losers
And the 6 stocks with the lowest returns:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | GYGY | Game Your Game | -31.3% | n/a |
| 2 | CALC | CalciMedica | -24.7% | -88.6% |
| 3 | MIRA | Mira Pharmaceuticals | -22.5% | -59.3% |
| 4 | EXYN | Exyn Technologies | -22.2% | n/a |
| 5 | FNGR | FingerMotion | -21.9% | -82.8% |
| 6 | EMAT | Evolution Metals & Technologies | -19.4% | n/a |
One day’s gain can create an entire month’s performance.
Aethlon Medical (AEMD) appears on both the one-day and one-month winners lists, but this is not a story of steady accumulation. The stock’s one-month return is +369.5%. Yet, according to the factbook, excluding today the other sessions returned -6.7%. The entire monthly gain came from this single session. This highlights the volatility often present in smaller companies; the market value of Aethlon Medical is about $5.2 million. An extreme return on one day can completely mask the underlying trend.
Movers Over The Last Week
Widening the window to five trading days, these are the strongest and weakest Market names:
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | AEMD | Aethlon Medical | 492.2% | 20.4% |
| 2 | FWAC | Futurewave Acquisition | 461.9% | 287.8% |
| 3 | HYFM | Hydrofarm | 220.8% | 42.4% |
| 4 | CYCU | Cycurion | 215.6% | -66.8% |
| 5 | LUNG | Pulmonx | 73.8% | -4.1% |
| 6 | RACC | Research Alliance Corporation III | 68.7% | n/a |
| 7 | TCX | Tucows | 60.4% | -38.7% |
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | YYAI | Airwa | -96.0% | -99.6% |
| 2 | BIOT | Instinct Bio Technical Company | -84.1% | n/a |
| 3 | MBRX | Moleculin Biotech | -80.6% | -87.2% |
| 4 | KPTI | Karyopharm Therapeutics | -72.2% | -73.2% |
| 5 | IMC | IMC Rare Earths | -59.4% | -59.4% |
| 6 | SDST | Stardust Power | -51.4% | -77.1% |
| 7 | DAIC | CID Holdco | -50.4% | -99.8% |
| 8 | BIOA | Bioage Labs | -48.4% | -18.5% |
Movers Over The Last Month
And over the last 21 trading days:
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | BRKH | Burtech Acquisition II | 641.8% | 409.7% |
| 2 | FWAC | Futurewave Acquisition | 559.3% | 287.8% |
| 3 | AEMD | Aethlon Medical | 369.5% | 20.4% |
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | YYAI | Airwa | -98.4% | -99.6% |
| 2 | LESL | Leslies | -87.5% | -34.5% |
| 3 | MBRX | Moleculin Biotech | -83.9% | -87.2% |
| 4 | CAPR | Capricor Therapeutics | -81.9% | -85.4% |
| 5 | KPTI | Karyopharm Therapeutics | -79.5% | -73.2% |
| 6 | ONFO | Onfolio | -77.1% | -87.1% |
A big move is a question, not an answer.
The tables earlier in this report are a map of market attention and risk, nothing more. A stock appearing on a winners or losers list is simply information. It is not an instruction to buy or sell. The disciplined follow-up is always to investigate the business behind the ticker. A sudden surge or drop prompts a question: what, if anything, has fundamentally changed? The movers list is the beginning of that work, never the end of it.
Either side of these lists can be a lead worth following, with the same follow-up question: does the business back the move? For the winners, our Guidance Momentum screen tracks which companies raised their own forward numbers. For the losers, our Buy the Dip screen flags which marked-down names still have the fundamentals to recover.
Volatility Is The Cost Of Owning Stocks. Concentration Makes It A Bill
Every name on these lists moved this much in a single day. A diversified holder reads that as noise; a concentrated holder feels it as real money. The difference is not the stock, it is the portfolio around it.
Building that portfolio is what the Trefis High Quality (HQ) Portfolio does: roughly 30 businesses with the cash generation and balance-sheet strength to absorb bad days, selected and rebalanced by rules. It has a track record of outpacing a benchmark that combines the three major indices – the S&P 500, S&P Mid-cap, and Russell 2000. Let the movers list remind you why diversification exists.