How Does Charles River Laboratories International Stock Compare With Peers?

CRL: Charles River Laboratories International logo
CRL
Charles River Laboratories International

Charles River Laboratories stock saw a 7% return over the past year, but how does it truly measure up against peers scaling in an AI-driven, evolving CRO market facing cost pressures and regulatory shifts? A closer look reveals negative LTM revenue growth and a challenging negative P/E, despite respectable operating and free cash flow margins. This presents a nuanced picture, suggesting headwinds for growth and valuation amidst competitive dynamics.

  • CRL’s 8.8% operating margin, well below MEDP’s 21.1%, reflects impacts from restructuring, lower service volume, and broader portfolio challenges.
  • CRL’s -0.9% revenue decline, lagging all peers, stems from weak biopharma spending and loss of key contracts.
  • CRL’s 7.2% stock gain is modest, with its -97.8 PE reflecting investor concern over recent losses and goodwill impairment.

Here’s how Charles River Laboratories International stacks up across size, valuation, and profitability versus key peers.

  CRL LH TMO IQV FTRE MEDP
Market Cap ($ Bil) 8.2 24.1 199.3 30.2 1.1 12.0
Revenue ($ Bil) 4.0 13.8 43.7 15.9 2.8 2.5
PE Ratio -97.8 28.2 30.3 23.5 -1.0 26.6
LTM Revenue Growth -0.9% 8.3% 3.2% 3.8% 1.9% 20.0%
LTM Operating Margin 8.8% 9.9% 18.4% 14.2% -2.4% 21.1%
LTM FCF Margin 13.5% 10.0% 14.0% 13.9% -0.6% 26.9%
12M Market Return 7.2% 19.6% -3.0% -11.8% -23.1% 29.3%

For more details on Charles River Laboratories International, read Buy or Sell CRL Stock. Below we compare CRL’s growth, margin, and valuation with peers across years

Trefis

Revenue Growth Comparison

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  LTM 2025 2024 2023 2022
CRL -0.9% -1.9% 3.9% 12.3%
LH 8.3% 7.0% 2.5% -9.7%
TMO 3.2% 0.1% -4.6% 14.5%
IQV 3.8% 2.8% 4.0% 3.9%
FTRE 1.9% -5.1% 0.2% -7.2%
MEDP 20.0% 20.0% 11.8% 29.2%  

Operating Margin Comparison

  LTM 2025 2024 2023 2022
CRL 8.8% 10.9% 14.9% 16.4%
LH 9.9% 8.7% 9.2% 14.8%
TMO 18.4% 18.0% 17.1% 18.9%
IQV 14.2% 14.7% 13.8% 12.7%
FTRE -2.4% -4.1% 1.9% 7.9%
MEDP 21.1% 21.1% 21.2% 17.9%  

PE Ratio Comparison

  LTM 2025 2024 2023 2022
CRL -97.8 995.4 19.9 24.7
LH 28.2 28.2 47.8 16.2
TMO 30.3 34.9 33.5 29.9
IQV 23.5 29.8 26.6 39.8
FTRE -1.0 -4.7 -65.7 16.6
MEDP 26.6 35.9 25.4 33.3  

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