8 Large Cap Stocks Hit 52-Week Highs On Thursday
As of Thursday, November 5, there are 8 Large Cap US and Canada-listed stocks in the Trefis coverage universe trading at their 52-week highs. Large Cap here means a market value above $40 billion.
McKesson (MCK), with a market value of about $124.7 billion, is the largest company on the list; its stock is up 17.8% over the past month and up 27.9% over the past year. By sector, Health Care leads the list with 3 of the 8 names. For context, the S&P 500 is down 5.7% over the past month, including dividends.

Every Name On The List
Here are all 8 names, sorted by market capitalization, with returns over four windows:
| Tickers | Market Cap |
1D Return |
1W Return |
1M Return |
1Y Return |
|---|---|---|---|---|---|
| MCK | $124.7 Bil | 0.2% | 9.3% | 17.8% | 27.9% |
| MSI | $85.6 Bil | 4.0% | 5.1% | 15.3% | 32.7% |
| RSG | $76.4 Bil | 1.6% | 5.6% | 15.4% | 21.5% |
| CAH | $62.1 Bil | 2.2% | 6.7% | 15.4% | 38.4% |
| EW | $58.1 Bil | 1.5% | 6.8% | 17.5% | 19.8% |
| KDP | $50.2 Bil | 0.3% | 4.5% | 20.8% | 43.9% |
| WCN | $48.2 Bil | 0.1% | 5.5% | 23.8% | 14.8% |
| ED | $44.8 Bil | 0.9% | 5.2% | 16.1% | 28.1% |
The Businesses Behind The Largest New Highs
McKesson (MCK) trades at 26.5 times trailing earnings, grew revenue 8.2% over the last twelve months and earned an operating margin of 1.7%.
Motorola Solutions (MSI) trades at 41.1 times trailing earnings, grew revenue 11.4% over the last twelve months and earned an operating margin of 25.4%.
Across the list, one-month moves range from +15.3% for Motorola Solutions (MSI) to +23.8% for Waste Connections (WCN).
Over the past year, the median name here is up 28.0%.
7 of the 8 names are also S&P 500 members.
A new high tells you what the market already believes. The harder question is which of these runs management itself is underwriting. Our Guidance Momentum screen tracks exactly that: stocks where the company raised its own forward numbers.
New Highs Fade. Discipline Compounds
Some of the names on this list will keep setting highs for years, and some are at the top of their run right now. Sorting one from the other, name by name, every day, is the work most investors never keep up with.
That sorting is what the Trefis High Quality (HQ) Portfolio does systematically: about 30 quality businesses screened for the fundamentals that sustain a run, held with rules instead of excitement. It has a track record of outpacing a benchmark that combines the S&P 500, the S&P MidCap 400, and the Russell 2000. Use the high list for ideas; use the portfolio for the compounding.