Market Movers | Winners: GEMI, FWDI, CYPH | Losers: XENE, KDK, HELP
A day of sharp divergence at the market’s edges raises questions about whether Friday’s biggest moves are new or just new chapters in older stories.
The S&P 500 gained +0.2% and the Nasdaq-100 added +0.7%, while the Dow Jones Industrial Average edged down 0.2%. Beneath that quiet surface, the day’s extremes were severe, with Gemini Space Station (GEMI) rising +31.2% as Xenon Pharmaceuticals (XENE) fell 30.7%. The question is whether these are isolated events or continuations of an existing trend.
The one-day tables below show the full range of Friday’s largest moves.

Friday’s Market Winners
The 10 US-listed stocks in the Trefis coverage universe with the highest returns on the last trading day:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | GEMI | Gemini Space Station | 31.2% | -41.4% |
| 2 | FWDI | Forward Industries | 24.2% | 16.5% |
| 3 | CYPH | Cypherpunk Technologies | 17.3% | 210.3% |
| 4 | MSTR | Strategy | 16.4% | 1.3% |
| 5 | BKKT | Bakkt | 15.4% | -14.2% |
| 6 | LVWR | LiveWire | 14.8% | -63.1% |
| 7 | ORBS | Eightco | 14.7% | -39.9% |
| 8 | ABTC | American Bitcoin | 14.4% | -60.4% |
| 9 | MARA | MARA | 13.7% | 47.4% |
| 10 | PS | Pershing Square | 13.7% | n/a |
Friday’s Market Losers
And the 10 US-listed stocks in the Trefis coverage universe with the lowest returns:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | XENE | Xenon Pharmaceuticals | -30.7% | -11.3% |
| 2 | KDK | Kodiak AI | -14.4% | -70.0% |
| 3 | HELP | Helus Pharma | -11.8% | n/a |
| 4 | GTN-A | Gray Media | -11.4% | -56.2% |
| 5 | ISOU | IsoEnergy | -11.1% | 1.9% |
| 6 | INDP | Indaptus Therapeutics | -9.7% | 22.0% |
| 7 | ELA | Envela | -8.9% | -6.9% |
| 8 | SMR | NuScale Power | -8.5% | -41.6% |
| 9 | CCHGY | Coca-Cola HBC | -8.3% | 12.2% |
| 10 | RSI | Rush Street Interactive | -7.7% | 19.9% |
Are these one-day moves or something more?
Several of the day’s biggest movers show persistent strength or weakness. Gemini Space Station (GEMI) appears on both the one-day and one-month winners lists. Its one-month return is +47.8%, and it still gained +12.7% over the other sessions excluding Friday. This performance is matched by a business that saw revenue grow 51.5% over the last twelve months.
The story is inverted for Xenon Pharmaceuticals (XENE), which is on both the one-day and one-month losers lists. Its one-month return is -36.2%, and it still lost 8.0% on the other days in that period. The company’s revenue declined 100.0% over the last twelve months.
Movers Over The Last Week
Widening the window to five trading days, these are the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | CYPH | Cypherpunk Technologies | 58.9% | 210.3% |
| 2 | SDGR | Schrodinger | 52.6% | 62.3% |
| 3 | LVWR | LiveWire | 43.0% | -63.1% |
| 4 | ELMT | Elmet | 41.9% | n/a |
| 5 | PS | Pershing Square | 32.3% | n/a |
| 6 | BBNX | Beta Bionics | 32.1% | -28.2% |
| 7 | TEM | Tempus AI | 31.9% | 31.8% |
| 8 | TWST | Twist Bioscience | 31.3% | 426.5% |
| 9 | EMAT | Evolution Metals & Technologies | 30.5% | n/a |
| 10 | GEMI | Gemini Space Station | 30.3% | -41.4% |
Losers
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | SWMR | Swarmer | -39.4% | n/a |
| 2 | ALHC | Alignment Healthcare | -33.8% | -57.7% |
| 3 | XENE | Xenon Pharmaceuticals | -32.2% | -11.3% |
| 4 | FLNC | Fluence Energy | -26.3% | -63.0% |
| 5 | PALI | Palisade Bio | -22.8% | -32.3% |
| 6 | ENVA | Enova International | -21.8% | 11.1% |
| 7 | VYX | NCR Voyix | -21.2% | -33.9% |
| 8 | ARWR | Arrowhead Pharmaceuticals | -19.8% | 0.1% |
| 9 | DMRA | Damora Therapeutics | -19.6% | -1.8% |
| 10 | OPFI | OppFi | -18.2% | -37.6% |
Movers Over The Last Month
And over the last 21 trading days, the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | INDP | Indaptus Therapeutics | 277.7% | 22.0% |
| 2 | CYPH | Cypherpunk Technologies | 236.4% | 210.3% |
| 3 | BRR | ProCap Financial | 79.0% | 6.5% |
| 4 | ARCT | Arcturus Therapeutics | 55.9% | 161.5% |
| 5 | FWDI | Forward Industries | 55.9% | 16.5% |
| 6 | TTRX | Turn Therapeutics | 52.1% | 279.2% |
| 7 | PURR | Hyperliquid Strategies | 50.1% | 295.8% |
| 8 | GEMI | Gemini Space Station | 47.8% | -41.4% |
| 9 | MSTR | Strategy | 47.6% | 1.3% |
| 10 | SMTC | Semtech | 47.6% | 151.1% |
Losers
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | ALMS | Alumis | -67.6% | -20.4% |
| 2 | SWMR | Swarmer | -46.9% | n/a |
| 3 | RARE | Ultragenyx Pharmaceutical | -44.7% | -36.9% |
| 4 | TTAN | ServiceTitan | -42.1% | -48.3% |
| 5 | FLNC | Fluence Energy | -39.4% | -63.0% |
| 6 | EYPT | EyePoint | -38.9% | -78.9% |
| 7 | KRMN | Karman | -38.6% | -51.1% |
| 8 | FBYD | Falcons Beyond Global | -36.4% | -53.6% |
| 9 | XENE | Xenon Pharmaceuticals | -36.2% | -11.3% |
| 10 | DYN | Dyne Therapeutics | -36.1% | -12.5% |
How should an investor use these lists?
A movers list is a map of where market attention is focused, not a set of instructions. The tables above show the largest percentage moves, which are often in smaller or more volatile names. A large gain or loss is simply information, signaling that something has changed.
The disciplined next step is not to chase the move but to investigate the business behind it. The names that appear across multiple time horizons, as seen in the one-week and one-month lists earlier, often merit the closest look. They point to trends that may have more behind them than a single day’s noise.
The next step is never to trade the list; it is to test it. Our Guidance Momentum screen shows which risers have management raising guidance behind them, and our Buy the Dip screen shows which of the fallers still generate the growth and cash that make a recovery plausible.
Volatility Is The Cost Of Owning Stocks. Concentration Makes It A Bill
Every name on these lists made a move big enough to notice. A diversified holder reads that as noise; a concentrated holder feels it as real money. The difference is not the stock, it is the portfolio around it.
Building that portfolio is what the Trefis High Quality (HQ) Portfolio does: roughly 30 businesses with the cash generation and balance-sheet strength to absorb bad days, selected and rebalanced by rules. It has a track record of outpacing a benchmark that combines the S&P 500, the S&P MidCap 400, and the Russell 2000. Let the movers list remind you why diversification exists.