Market Movers | Winners: KOD, CD, QNC | Losers: ITG, OCUL, CYPH
A large single-day stock gain on an otherwise down day raises questions about what makes a trend.
Major indexes fell on Monday, with the S&P 500 returning -0.8%. Against that backdrop, the day’s most extreme move belonged to Kodiak Sciences (KOD), which returned +178.0%. The central question raised by such an outlier is whether its strength is a sudden event or part of a sustained trend. The day’s largest percentage moves follow.

Monday’s Market Winners
The 10 US-listed stocks in the Trefis coverage universe with the highest returns on the last trading day:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | KOD | Kodiak Sciences | 178.0% | 221.6% |
| 2 | CD | Chaince Digital | 22.3% | 31.2% |
| 3 | QNC | Quantum eMotion | 17.0% | -40.2% |
| 4 | SFIX | Stitch Fix | 14.6% | -53.0% |
| 5 | FBYD | Falcons Beyond Global | 12.5% | -44.3% |
| 6 | AMC | AMC Entertainment | 11.9% | 110.9% |
| 7 | AGEN | Agenus | 10.4% | 200.3% |
| 8 | ANNX | Annexon | 10.2% | -20.1% |
| 9 | ABCL | AbCellera Biologics | 9.6% | 307.0% |
| 10 | HHH | Howard Hughes | 8.1% | -7.3% |
Monday’s Market Losers
And the 10 US-listed stocks in the Trefis coverage universe with the lowest returns:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | ITG | ITG | -32.6% | n/a |
| 2 | OCUL | Ocular Therapeutix | -20.7% | -36.9% |
| 3 | CYPH | Cypherpunk Technologies | -19.7% | 185.3% |
| 4 | MDB | MongoDB | -18.5% | -20.3% |
| 5 | CCB | Coastal Financial | -16.2% | -67.2% |
| 6 | INDP | Indaptus Therapeutics | -14.5% | 13.1% |
| 7 | AUR | Aurora Innovation | -12.4% | 37.8% |
| 8 | MOD | Modine Manufacturing | -11.6% | 31.1% |
| 9 | ASPI | ASP Isotopes | -11.1% | -51.4% |
| 10 | ENVX | Enovix | -11.0% | -65.0% |
This stock’s weakness has been building for weeks.
ITG was the weakest name on the tape, returning -32.6%. The stock also appears on the one-month losers list, where its return is -45.1%. This is not a one-day event, as the stock lost 18.6% over the other sessions in that period. The company trades at 25.8 times trailing earnings (on trailing earnings that include at least one loss quarter, so the multiple is not comparable to a clean-year multiple).
Movers Over The Last Week
Widening the window to five trading days, these are the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | KOD | Kodiak Sciences | 177.4% | 221.6% |
| 2 | SRZN | Surrozen | 79.3% | 31.2% |
| 3 | CD | Chaince Digital | 67.6% | 31.2% |
| 4 | BALY | Ballys | 32.6% | -15.3% |
| 5 | DNA | Ginkgo Bioworks | 31.1% | 25.9% |
| 6 | VICR | Vicor | 27.3% | 160.1% |
| 7 | PACB | Pacific Biosciences of California | 25.7% | -8.6% |
| 8 | QNC | Quantum eMotion | 24.3% | -40.2% |
| 9 | FBYD | Falcons Beyond Global | 23.1% | -44.3% |
| 10 | GRAL | GRAIL | 22.8% | 55.0% |
Losers
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | ITG | ITG | -39.4% | n/a |
| 2 | XNDU | Xanadu Quantum Technologies | -35.3% | n/a |
| 3 | KDK | Kodiak AI | -30.6% | -79.2% |
| 4 | CGEM | Cullinan Therapeutics | -30.0% | 44.4% |
| 5 | CTEV | Claritev | -28.9% | -47.4% |
| 6 | BYND | Beyond Meat | -28.5% | -65.4% |
| 7 | GEN | Gen Digital | -28.5% | -22.2% |
| 8 | ALKT | Alkami Technology | -27.7% | -42.0% |
| 9 | EOSE | Eos Energy Enterprises | -24.6% | -73.2% |
| 10 | OCUL | Ocular Therapeutix | -23.4% | -36.9% |
Movers Over The Last Month
And over the last 21 trading days, the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | INDP | Indaptus Therapeutics | 183.6% | 13.1% |
| 2 | KOD | Kodiak Sciences | 129.9% | 221.6% |
| 3 | CD | Chaince Digital | 90.6% | 31.2% |
| 4 | SVIA | Silvia | 80.6% | 10.5% |
| 5 | CYPH | Cypherpunk Technologies | 75.1% | 185.3% |
| 6 | GRAL | GRAIL | 60.8% | 55.0% |
| 7 | MNTK | Montauk Renewables | 55.6% | 67.7% |
| 8 | BALY | Ballys | 53.8% | -15.3% |
| 9 | ACVA | ACV Auctions | 44.9% | 30.4% |
| 10 | SDGR | Schrodinger | 44.5% | 65.0% |
Losers
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | ALMS | Alumis | -69.2% | -26.6% |
| 2 | XNDU | Xanadu Quantum Technologies | -54.0% | n/a |
| 3 | RARE | Ultragenyx Pharmaceutical | -45.1% | -37.3% |
| 4 | ITG | ITG | -45.1% | n/a |
| 5 | KDK | Kodiak AI | -42.8% | -79.2% |
| 6 | CTEV | Claritev | -42.1% | -47.4% |
| 7 | IMUX | Immunic | -41.7% | 78.2% |
| 8 | ALHC | Alignment Healthcare | -41.5% | -59.8% |
| 9 | CABA | Cabaletta Bio | -40.8% | -8.7% |
| 10 | XENE | Xenon Pharmaceuticals | -40.7% | -18.1% |
A movers list is a map of attention, not a set of instructions.
The tables appearing earlier show the largest percentage gains and losses over several time horizons. A name appearing on these lists is a signal that something has captured market notice, for better or worse. It is information about risk and attention.
A large move is never an instruction to act. The disciplined response is to treat it as a starting point for research. The essential follow-up is to check the business fundamentals behind the stock’s new price.
Either side of these lists can be a lead worth following, with the same follow-up question: does the business back the move? For the winners, our Guidance Momentum screen tracks which companies raised their own forward numbers. For the losers, our Buy the Dip screen flags which marked-down names still have the fundamentals to recover.
Volatility Is The Cost Of Owning Stocks. Concentration Makes It A Bill
Every name on these lists made a move big enough to notice. A diversified holder reads that as noise; a concentrated holder feels it as real money. The difference is not the stock, it is the portfolio around it.
Building that portfolio is what the Trefis High Quality (HQ) Portfolio does: roughly 30 businesses with the cash generation and balance-sheet strength to absorb bad days, selected and rebalanced by rules. It has a track record of outpacing a benchmark that combines the S&P 500, the S&P MidCap 400, and the Russell 2000. Let the movers list remind you why diversification exists.