Alnylam Pharmaceuticals Stock: 5 Straight Red Days, Down 14%

ALNYYTD-44.7%SPYYTD+13.5%XLVYTD+8.3%
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Shares of Alnylam Pharmaceuticals (ALNY) have closed lower in each of the last 5 sessions, a cumulative decline of 14.2%. That erased about $4.8 billion from the company’s market value, which now stands at about $29.4 billion. The stock closed at $219.72 on Friday, October 2, 55.3% below its 52-week high of $491.22 and 6.9% above its low of $205.48.

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ALNY Versus The S&P 500

Returns for ALNY and the S&P 500 over the streak and the periods around it, all ending Friday, October 2 and including dividends:
 

Return Period ALNY S&P 500
1 Day -5.0% 0.7%
5 Days (Current Streak) -14.2% -0.2%
1 Month (21 Trading Days) -17.8% 0.8%
3 Months (63 Trading Days) -29.8% 2.7%
Year To Date -44.7% 13.8%
1 Year (252 Trading Days) -52.3% 16.4%

A Stock-Specific Slide, Or A Market Move?

Over the same 5 trading days, the S&P 500 returned -0.2% including dividends, so the slide is mostly Alnylam Pharmaceuticals’ own story rather than the market’s. Over the past three months the stock is down 29.8%, a window that includes the streak; over the other 58 sessions of that window it was down 18.2%.

What The Numbers Say About The Slide

On the fundamentals, revenue grew 95.1% over the last twelve months, against a median of 8.1% for S&P 500 Health Care stocks; its operating margin is 20.8%, versus a median of 18.3%; and the stock trades at 36.3 times trailing earnings against a median of 28.3. The read is mixed.

If the drop has you weighing an entry, resist buying on price alone. Our Buy the Dip screen ranks the marked-down names where growth and cash generation still hold up.

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A Slide Like This Is Why Diversification Exists

Watching one stock fall day after day is the clearest lesson the market teaches about single-name risk. Whether this particular decline is an opportunity or a warning, the deeper point is the same: no one name should be able to do this to your portfolio.

The Trefis High Quality (HQ) Portfolio is built on that principle: roughly 30 businesses selected for consistent cash generation, strong margins, and resilient balance sheets, sized and rebalanced with rules. It has a track record of outpacing a benchmark that combines the S&P 500, the S&P MidCap 400, and the Russell 2000. Study the slide; spread the risk.