Tearsheet

Thermo Fisher Scientific (TMO)


Market Price (11/24/2025): $587.1 | Market Cap: $221.9 Bil
Sector: Health Care | Industry: Life Sciences Tools & Services

Thermo Fisher Scientific (TMO)


Market Price (11/24/2025): $587.1
Market Cap: $221.9 Bil
Sector: Health Care
Industry: Life Sciences Tools & Services

Investment Highlights Why It Matters Which of these 2 stories sounds closer for this stock?

1. Generates cash flow

The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.

2. Riding a trend

Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow


0 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 17%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 14%, CFO LTM is 7.7 Bil, FCF LTM is 6.1 Bil
Trading close to highs
Dist 52W High is -2.9%
Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 26x, P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 29x, P/EPrice/Earnings or Price/(Net Income) is 34x
1 Low stock price volatility
Vol 12M is 32%
Weak multi-year price returns
2Y Excs Rtn is -20%, 3Y Excs Rtn is -56%
Weak revenue growth
Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -0.3%
2 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Advanced Diagnostics, Show more.
  
0 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 17%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 14%, CFO LTM is 7.7 Bil, FCF LTM is 6.1 Bil
1 Low stock price volatility
Vol 12M is 32%
2 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Advanced Diagnostics, Show more.
3 Trading close to highs
Dist 52W High is -2.9%
4 Weak multi-year price returns
2Y Excs Rtn is -20%, 3Y Excs Rtn is -56%
5 Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 26x, P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 29x, P/EPrice/Earnings or Price/(Net Income) is 34x
6 Weak revenue growth
Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -0.3%

Valuation, Metrics & Events

TMO Stock


Why The Stock Moved


Qualitative Assessment

AI Generated Analysis | Feedback

1. Strong Q2 2025 Earnings Beat and Positive Outlook.

Thermo Fisher Scientific reported robust financial results for the second quarter of 2025 on July 23, 2025, with revenue reaching $10.85 billion, surpassing market expectations of $10.68 billion. This represented a 3% increase in revenue, with organic growth of 2%. The company's non-GAAP earnings per share (EPS) for the quarter stood at $5.36, exceeding analyst estimates of $5.24. This strong performance led to an 8.22% surge in Thermo Fisher's stock in pre-market trading, reflecting positive market sentiment towards the company's performance and strategic initiatives. 2. Robust Q3 2025 Earnings Beat and Raised Full-Year Guidance.

On October 22, 2025, Thermo Fisher Scientific announced impressive third-quarter 2025 financial results. The company reported a 5% increase in revenue to $11.12 billion and a 10% rise in adjusted EPS to $5.79, both exceeding analyst expectations. Following these results, management raised its full-year 2025 guidance for both revenue and adjusted EPS, indicating strong confidence in its continued operational execution and future outlook. This positive earnings report contributed to a pre-market share increase of approximately 2%. 3. Strategic Acquisitions Driving Growth and Capacity Expansion.

Thermo Fisher Scientific made several strategic acquisitions during this period aimed at expanding its capabilities and market presence. Notably, the company completed the acquisition of Sanofi's sterile fill-finish and packaging site in Ridgefield, New Jersey, by September 2, 2025, significantly expanding its U.S. drug product manufacturing capabilities. Furthermore, the anticipated acquisition of Solventum's purification and filtration business for approximately $4.1 billion is expected to complement its bioproduction unit and contribute to mid-to-high single-digit organic growth by year-end 2025. 4. Significant Share Buyback Program.

The company's board of directors approved a substantial $5.0 billion share buyback program on November 6, 2025. This authorization allows Thermo Fisher to repurchase up to 2.4% of its outstanding shares through open market purchases, signaling strong financial health, a commitment to returning value to shareholders, and confidence in the company's future prospects. 5. Innovation and Strategic AI Collaboration.

Thermo Fisher Scientific demonstrated a strong focus on innovation, including a strategic collaboration with OpenAI, announced on October 22, 2025, to integrate artificial intelligence across its operations, products, and services to accelerate scientific breakthroughs and enhance drug development. Additionally, the company launched new advanced instruments, such as next-generation mass spectrometers in July, and received FDA approval on November 20, 2025, for its Oncomine Dx Target Test as a companion diagnostic for non-small cell lung cancer, showcasing continuous product development and market expansion.

Show more

Stock Movement Drivers

Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
TMO Return44%44%-17%-3%-2%13%84%
Peers Return35%37%-25%42%6%46%207%
S&P 500 Return16%27%-19%24%23%12%104%

Monthly Win Rates [3]
TMO Win Rate67%75%42%58%50%50% 
Peers Win Rate62%56%40%63%48%52% 
S&P 500 Win Rate58%75%42%67%75%70% 

Max Drawdowns [4]
TMO Max Drawdown-21%-6%-27%-22%-5%-25% 
Peers Max Drawdown-33%-4%-35%-4%-7%-22% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: MU, AMAT, TXN, ADI, AVRT. See TMO Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 11/21/2025 (YTD)

How Low Can It Go

Unique KeyEventTMOS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-35.3%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven54.7%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-24.9%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven33.2%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven35 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-17.3%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven20.9%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven53 days120 days
2008 Global Financial Crisis2008 Global Financial Crisis  
2008 Global Financial Crisis% Loss% Loss-53.9%-56.8%
2008 Global Financial Crisis% Gain to Breakeven% Gain to Breakeven117.0%131.3%
2008 Global Financial CrisisTime to BreakevenTime to Breakeven909 days1480 days

Compare to MU, AMAT, TXN, ADI, AVRT


In The Past

Thermo Fisher Scientific's stock fell -35.3% during the 2022 Inflation Shock from a high on 12/31/2021. A -35.3% loss requires a 54.7% gain to breakeven.

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About Thermo Fisher Scientific (TMO)

Better Bets than Thermo Fisher Scientific (TMO)

Latest Trefis Analyses

Trade Ideas

Select past ideas related to TMO. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
GDRX_10312025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG10312025GDRXGoodRxDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
-19.6%-19.6%-22.3%
DXCM_10312025_Monopoly_xInd_xCD_Getting_Cheaper10312025DXCMDexComMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
3.5%3.5%-5.8%
TXN_10312025_Monopoly_xInd_xCD_Getting_Cheaper10312025TXNTexas InstrumentsMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-1.3%-1.3%-5.0%
ACHC_10242025_Dip_Buyer_ValueBuy10242025ACHCAcadia HealthcareDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
-35.1%-35.1%-38.7%
PBH_10102025_Dip_Buyer_ValueBuy10102025PBHPrestige Consumer HealthcareDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
-2.6%-2.6%-4.1%
TMO_4302025_Monopoly_xInd_xCD_Getting_Cheaper04302025TMOThermo Fisher ScientificMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
30.4%37.2%-8.9%
TMO_9302022_Monopoly_xInd_xCD_Getting_Cheaper09302022TMOThermo Fisher ScientificMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
13.8%0.1%-4.4%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
GDRX_10312025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG10312025GDRXGoodRxDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
-19.6%-19.6%-22.3%
DXCM_10312025_Monopoly_xInd_xCD_Getting_Cheaper10312025DXCMDexComMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
3.5%3.5%-5.8%
TXN_10312025_Monopoly_xInd_xCD_Getting_Cheaper10312025TXNTexas InstrumentsMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-1.3%-1.3%-5.0%
ACHC_10242025_Dip_Buyer_ValueBuy10242025ACHCAcadia HealthcareDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
-35.1%-35.1%-38.7%
PBH_10102025_Dip_Buyer_ValueBuy10102025PBHPrestige Consumer HealthcareDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
-2.6%-2.6%-4.1%
TMO_4302025_Monopoly_xInd_xCD_Getting_Cheaper04302025TMOThermo Fisher ScientificMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
30.4%37.2%-8.9%
TMO_9302022_Monopoly_xInd_xCD_Getting_Cheaper09302022TMOThermo Fisher ScientificMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
13.8%0.1%-4.4%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for Thermo Fisher Scientific

Financials

TMOMUAMATTXNADIAVRTMedian
NameThermo F.Micron T.Applied .Texas In.Analog D.Avertix . 
Mkt Price587.48207.37224.00159.40232.32-224.00
Mkt Cap222.1232.7178.8144.9114.9-178.8
Rev LTM43,73537,37828,61317,26610,387-28,613
Op Inc LTM8,0519,8098,6236,0122,630-8,051
FCF LTM6,1111,6685,8232,0803,678-3,678
FCF 3Y Avg6,811-1,4436,4571,7323,439-3,439
CFO LTM7,65117,5257,7056,8974,162-7,651
CFO 3Y Avg8,3079,1977,7886,5604,310-7,788

Growth & Margins

TMOMUAMATTXNADIAVRTMedian
NameThermo F.Micron T.Applied .Texas In.Analog D.Avertix . 
Rev Chg LTM3.2%48.9%6.6%9.9%7.1%-7.1%
Rev Chg 3Y Avg-0.3%20.3%4.4%-4.6%-0.6%--0.3%
Rev Chg Q4.9%46.0%7.7%14.2%24.6%-14.2%
QoQ Delta Rev Chg LTM1.2%10.5%1.9%3.5%5.8%-3.5%
Op Mgn LTM18.4%26.2%30.1%34.8%25.3%-26.2%
Op Mgn 3Y Avg17.6%-1.1%29.4%38.0%27.5%-27.5%
QoQ Delta Op Mgn LTM0.2%3.7%0.5%-0.1%1.8%-0.5%
CFO/Rev LTM17.5%46.9%26.9%39.9%40.1%-39.9%
CFO/Rev 3Y Avg19.3%30.3%28.5%38.6%39.5%-30.3%
FCF/Rev LTM14.0%4.5%20.4%12.0%35.4%-14.0%
FCF/Rev 3Y Avg15.8%-11.5%23.7%10.2%31.5%-15.8%

Valuation

TMOMUAMATTXNADIAVRTMedian
NameThermo F.Micron T.Applied .Texas In.Analog D.Avertix . 
Mkt Cap222.1232.7178.8144.9114.9-178.8
P/S5.16.26.28.411.1-6.2
P/EBIT26.223.019.523.343.3-23.3
P/E33.827.226.228.758.7-28.7
P/CFO29.013.323.221.027.6-23.2
Total Yield3.0%3.9%4.6%6.9%3.4%-3.9%
Dividend Yield0.0%0.2%0.8%3.4%1.6%-0.8%
FCF Yield 3Y Avg3.3%-2.4%4.4%1.1%3.2%-3.2%
D/E0.20.10.00.10.1-0.1
Net D/E0.10.0-0.00.10.0-0.0

Returns

TMOMUAMATTXNADIAVRTMedian
NameThermo F.Micron T.Applied .Texas In.Analog D.Avertix . 
1M Rtn2.6%-5.3%-1.9%-5.8%-2.4%--2.4%
3M Rtn17.6%76.3%38.1%-22.0%-7.5%-17.6%
6M Rtn49.5%122.4%42.9%-8.1%11.3%-42.9%
12M Rtn14.9%102.9%29.4%-16.9%10.1%-14.9%
3Y Rtn8.3%257.7%113.7%-2.5%44.8%-44.8%
1M Excs Rtn4.7%2.3%0.2%-4.6%-2.5%-0.2%
3M Excs Rtn17.3%75.7%36.0%-24.5%-10.9%-17.3%
6M Excs Rtn35.7%108.7%29.1%-21.9%-2.5%-29.1%
12M Excs Rtn4.2%101.5%22.3%-29.7%0.7%-4.2%
3Y Excs Rtn-56.2%191.2%54.6%-66.2%-14.9%--14.9%

Financials

Segment Financials

Revenue by Segment

$ Mil20242023202220212020
Laboratory Products and Biopharma Services23,04122,51114,86212,24510,599
Life Sciences Solutions9,97713,53215,63112,1686,856
Analytical Instruments7,2636,6246,0695,1245,522
Specialty Diagnostics4,4054,7635,6595,3433,718
Elimination of intersegment revenues-1,829-2,515-3,010-2,662-1,153
Total42,85744,91539,21132,21825,542


Operating Income by Segment
$ Mil20242023202220212020
Life Sciences Solutions3,4205,5827,8176,1092,446
Laboratory Products and Biopharma Services3,3582,8721,8441,2711,324
Analytical Instruments1,9081,5071,1978081,273
Specialty Diagnostics1,1241,0241,2801,368930
Selling, general and administrative expenses adjustments-59-37-14410-62
Cost of revenues adjustments-95-46-8-6-17
Restructuring and other costs-459-114-197-99413
Amortization of acquisition-related intangible assets-2,338-2,395-1,761-1,667-1,713
Total6,8598,39310,0287,7944,594


Assets by Segment
$ Mil20242023202220212020
Unallocated amounts85,314    
Laboratory Products and Biopharma Services6,35051,28152,63922,71121,761
Life Sciences Solutions3,18621,84822,75120,20918,306
Analytical Instruments2,72610,0199,6929,7739,896
Specialty Diagnostics1,1505,5426,0106,5345,867
Corporate/Other 8,4644,0319,8252,551
Total98,72697,15495,12369,05258,381


Price Behavior

Short Interest

Short Interest: As Of Date10312025
Short Interest: Shares Quantity4,409,154
Short Interest: % Change Since 1015202512.8%
Average Daily Volume2,043,124
Days-to-Cover Short Interest2.16
Basic Shares Quantity378,000,000
Short % of Basic Shares1.2%

Earnings Returns History

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 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
10/22/20251.7%-0.1%2.8%
7/23/20259.1%12.8%15.7%
4/23/2025-0.7%-1.7%-8.4%
1/30/20256.8%2.5%-6.9%
10/23/2024-1.7%-6.6%-12.5%
7/24/20244.1%11.4%10.5%
4/24/20240.5%-1.0%2.8%
1/31/2024-5.0%-1.2%0.5%
...
SUMMARY STATS   
# Positive151213
# Negative91211
Median Positive2.7%4.3%4.1%
Median Negative-2.8%-1.4%-6.9%
Max Positive9.1%12.8%15.7%
Max Negative-5.5%-6.6%-12.9%

SEC Filings

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Report DateFiling DateFiling
93020251031202510-Q 9/27/2025
6302025801202510-Q 6/28/2025
3312025502202510-Q 3/29/2025
12312024220202510-K 12/31/2024
93020241101202410-Q 9/30/2024
6302024802202410-Q 6/29/2024
3312024503202410-Q 3/30/2024
12312023222202410-K 12/31/2023
93020231103202310-Q 9/30/2023
6302023804202310-Q 7/1/2023
3312023505202310-Q 4/1/2023
12312022223202310-K 12/31/2022
93020221104202210-Q 10/1/2022
6302022805202210-Q 7/2/2022
3312022506202210-Q 4/2/2022
12312021224202210-K 12/31/2021

Insider Activity

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