Thermo Fisher Scientific (TMO)


Market Price (7/24/2026): $569.25 | Market Cap: $211.8 BilInvestor Relations Sector: Health Care | Industry: Life Sciences Tools & Services

Thermo Fisher Scientific (TMO)


Market Price (7/24/2026): $569.25
Market Cap: $211.8 Bil
Sector: Health Care
Industry: Life Sciences Tools & Services

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

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Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 18%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 15%, CFO LTM is 8.3 Bil, FCF LTM is 6.7 Bil

Stock buyback support
Stock Buyback 3Y Total is 10 Bil

Low stock price volatility
Vol 12M is 32%

Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Advanced Diagnostics, Show more.

Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 24x, P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 26x, P/EPrice/Earnings or Price/(Net Income) is 31x

Key risks
TMO key risks include [1] dampened demand from potential cuts in government research funding and new tariffs, Show more.

0 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 18%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 15%, CFO LTM is 8.3 Bil, FCF LTM is 6.7 Bil
1 Stock buyback support
Stock Buyback 3Y Total is 10 Bil
2 Low stock price volatility
Vol 12M is 32%
3 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Advanced Diagnostics, Show more.
4 Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 24x, P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 26x, P/EPrice/Earnings or Price/(Net Income) is 31x
5 Key risks
TMO key risks include [1] dampened demand from potential cuts in government research funding and new tariffs, Show more.

TMO in ETFs

Weight = TMO's share of each fund

SPY0.30%
VOO0.29%
IVV0.31%
VTI0.26%
ITOT0.28%
IWB0.29%
RSP0.22%
VTV0.70%
+25 more covered ETFs

Valuation & Metrics

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Updated on 7/23/2026

Thermo Fisher Scientific (TMO) stock has gained about 15% since 3/31/2026 because of the following key factors:

1. Exceptional Fiscal Q2 2026 Earnings Beat and Robust Growth.

Thermo Fisher Scientific reported adjusted earnings per share (EPS) of $6.03 in fiscal Q2 2026, which ended June 27, 2026, surpassing analyst estimates of $5.72 by 5.4%. The company's revenue also exceeded expectations, reaching $11.99 billion against an estimated $11.71 billion. This represents a 10% year-over-year revenue growth, including 5% organic growth, and adjusted EPS growth of 13% year-over-year.

2. Increased Full-Year 2026 Financial Guidance.

Following its strong fiscal Q2 2026 performance, Thermo Fisher Scientific raised its full-year 2026 revenue guidance to a range of $47.4 billion to $48.1 billion, reflecting 6% to 8% reported growth. The adjusted EPS guidance was also increased to $24.93 to $25.33, an uplift of $0.25 at the midpoint from previous guidance, signaling management's confidence in continued operational strength and an expectation for second-half organic growth to step up to 4% from 3% in the first half.

Show more
Updated on 7/23/2026

Thermo Fisher Scientific (TMO) stock has gained about 15% since 3/31/2026 because of the following key factors:

1. Exceptional Fiscal Q2 2026 Earnings Beat and Robust Growth.

Thermo Fisher Scientific reported adjusted earnings per share (EPS) of $6.03 in fiscal Q2 2026, which ended June 27, 2026, surpassing analyst estimates of $5.72 by 5.4%. The company's revenue also exceeded expectations, reaching $11.99 billion against an estimated $11.71 billion. This represents a 10% year-over-year revenue growth, including 5% organic growth, and adjusted EPS growth of 13% year-over-year.

2. Increased Full-Year 2026 Financial Guidance.

Following its strong fiscal Q2 2026 performance, Thermo Fisher Scientific raised its full-year 2026 revenue guidance to a range of $47.4 billion to $48.1 billion, reflecting 6% to 8% reported growth. The adjusted EPS guidance was also increased to $24.93 to $25.33, an uplift of $0.25 at the midpoint from previous guidance, signaling management's confidence in continued operational strength and an expectation for second-half organic growth to step up to 4% from 3% in the first half.

3. Broad-Based Market Strengthening and Strategic Innovation.

Thermo Fisher Scientific experienced strengthened customer activity across all its end markets in fiscal Q2 2026, particularly in pharma and biotech, which remained the largest contributors. All four business segments demonstrated growth, with Life Sciences Solutions revenue increasing 13% (3% organic) and Analytical Instruments growing 7% (reported and organic). The company also introduced new, high-impact innovations, such as next-generation Orbitrap mass spectrometry platforms with AI-driven analytics, enhancing its leadership in the life sciences tools and diagnostics sector.

4. Strategic Capital Deployment and Acquisitions.

The company demonstrated effective capital deployment by repurchasing $1.0 billion of common stock in fiscal Q2 2026. Additionally, the successful integration of recent acquisitions, such as Clario completed in late fiscal Q1 2026, contributed to revenue and earnings growth, while the planned divestiture of its microbiology business allows for enhanced strategic focus.

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Stock Movement Drivers

Fundamental Drivers

The 16.6% change in TMO stock from 3/31/2026 to 7/23/2026 was primarily driven by a 13.5% change in the company's P/E Multiple.
(LTM values as of)33120267232026Change
Stock Price ($)491.04572.3216.6%
Change Contribution By: 
Total Revenues ($ Mil)44,55545,1961.4%
Net Income Margin (%)15.0%15.2%0.7%
P/E Multiple27.431.113.5%
Shares Outstanding (Mil)3743720.5%
Cumulative Contribution16.6%

LTM = Last Twelve Months as of date shown

Market Drivers

3/31/2026 to 7/23/2026
ReturnCorrelation
TMO16.6% 
Market (SPY)13.5%13.6%
Sector (XLV)10.1%45.2%

Fundamental Drivers

The -1.0% change in TMO stock from 12/31/2025 to 7/23/2026 was primarily driven by a -6.6% change in the company's P/E Multiple.
(LTM values as of)123120257232026Change
Stock Price ($)578.30572.32-1.0%
Change Contribution By: 
Total Revenues ($ Mil)43,73545,1963.3%
Net Income Margin (%)15.0%15.2%0.9%
P/E Multiple33.331.1-6.6%
Shares Outstanding (Mil)3783721.6%
Cumulative Contribution-1.0%

LTM = Last Twelve Months as of date shown

Market Drivers

12/31/2025 to 7/23/2026
ReturnCorrelation
TMO-1.0% 
Market (SPY)8.5%28.0%
Sector (XLV)4.7%45.2%

Fundamental Drivers

The 41.7% change in TMO stock from 6/30/2025 to 7/23/2026 was primarily driven by a 32.6% change in the company's P/E Multiple.
(LTM values as of)63020257232026Change
Stock Price ($)403.99572.3241.7%
Change Contribution By: 
Total Revenues ($ Mil)42,89845,1965.4%
Net Income Margin (%)15.2%15.2%-0.2%
P/E Multiple23.431.132.6%
Shares Outstanding (Mil)3783721.6%
Cumulative Contribution41.7%

LTM = Last Twelve Months as of date shown

Market Drivers

6/30/2025 to 7/23/2026
ReturnCorrelation
TMO41.7% 
Market (SPY)20.5%28.3%
Sector (XLV)21.3%54.6%

Fundamental Drivers

The 10.8% change in TMO stock from 6/30/2023 to 7/23/2026 was primarily driven by a 10.2% change in the company's Net Income Margin (%).
(LTM values as of)63020237232026Change
Stock Price ($)516.77572.3210.8%
Change Contribution By: 
Total Revenues ($ Mil)43,80745,1963.2%
Net Income Margin (%)13.8%15.2%10.2%
P/E Multiple33.131.1-6.1%
Shares Outstanding (Mil)3863723.8%
Cumulative Contribution10.8%

LTM = Last Twelve Months as of date shown

Market Drivers

6/30/2023 to 7/23/2026
ReturnCorrelation
TMO10.8% 
Market (SPY)72.4%43.1%
Sector (XLV)27.3%61.7%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
TMO Return44%-17%-3%-2%12%-9%15%
Peers Return28%-15%-9%1%-2%4%2%
S&P 500 Return27%-19%24%23%16%10%100%

Monthly Win Rates [3]
TMO Win Rate75%42%58%50%50%43% 
Peers Win Rate73%40%43%47%48%46% 
S&P 500 Win Rate75%42%67%75%67%43% 

Max Drawdowns [4]
TMO Max Drawdown-15%-27%-29%-20%-36%-31% 
Peers Max Drawdown-20%-33%-34%-20%-37%-27% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: DHR, A, ILMN, BDX, WAT. See TMO Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 7/23/2026 (YTD)

How Low Can It Go

EventTMOS&P 500
2025 US Tariff Shock
  % Loss-25.8%-18.8%
  % Gain to Breakeven34.7%23.1%
  Time to Breakeven131 days79 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-24.4%-9.5%
  % Gain to Breakeven32.2%10.5%
  Time to Breakeven124 days24 days
2023 SVB Regional Banking Crisis
  % Loss-11.5%-6.7%
  % Gain to Breakeven13.0%7.1%
  Time to Breakeven56 days31 days
2022 Inflation Shock & Fed Tightening
  % Loss-24.4%-24.5%
  % Gain to Breakeven32.2%32.4%
  Time to Breakeven1190 days427 days
2020 COVID-19 Crash
  % Loss-24.8%-33.7%
  % Gain to Breakeven33.0%50.9%
  Time to Breakeven35 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-15.7%-19.2%
  % Gain to Breakeven18.6%23.8%
  Time to Breakeven44 days105 days

Compare to DHR, A, ILMN, BDX, WAT

In The Past

Thermo Fisher Scientific's stock fell -25.8% during the 2025 US Tariff Shock. Such a loss loss requires a 34.7% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventTMOS&P 500
2025 US Tariff Shock
  % Loss-25.8%-18.8%
  % Gain to Breakeven34.7%23.1%
  Time to Breakeven131 days79 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-24.4%-9.5%
  % Gain to Breakeven32.2%10.5%
  Time to Breakeven124 days24 days
2022 Inflation Shock & Fed Tightening
  % Loss-24.4%-24.5%
  % Gain to Breakeven32.2%32.4%
  Time to Breakeven1190 days427 days
2020 COVID-19 Crash
  % Loss-24.8%-33.7%
  % Gain to Breakeven33.0%50.9%
  Time to Breakeven35 days140 days
2011 US Debt Ceiling Crisis & European Contagion
  % Loss-25.5%-17.9%
  % Gain to Breakeven34.3%21.8%
  Time to Breakeven411 days123 days
2008-2009 Global Financial Crisis
  % Loss-51.1%-53.4%
  % Gain to Breakeven104.6%114.4%
  Time to Breakeven888 days1085 days

Compare to DHR, A, ILMN, BDX, WAT

In The Past

Thermo Fisher Scientific's stock fell -25.8% during the 2025 US Tariff Shock. Such a loss loss requires a 34.7% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Thermo Fisher Scientific (TMO)

Thermo Fisher Scientific (TMO) is a global leader in providing an extensive range of scientific products and services. The company essentially equips scientists, researchers, and clinicians with the essential tools and support necessary for scientific discovery, diagnostics, and production across various industries. Operating through distinct segments, Thermo Fisher addresses critical needs within the global scientific and healthcare communities.

The company's core offerings include life sciences solutions, providing reagents, instruments, and consumables vital for biological and medical research, drug and vaccine development, and disease diagnosis. They also specialize in analytical instruments, software, and services used for precise measurement and analysis in laboratories and industrial settings. Furthermore, Thermo Fisher supplies specialty diagnostic products, such as immunodiagnostic kits for allergy, asthma, and autoimmunity testing, alongside a broad portfolio of laboratory products like refrigerators, centrifuges, chemicals, and comprehensive pharmaceutical services.

Thermo Fisher's diverse customer base primarily consists of pharmaceutical and biotechnology companies, academic and government research institutions, clinical laboratories, hospitals, and environmental organizations. Their products and services are indispensable for a wide array of applications, spanning cutting-edge scientific research, new drug development, routine clinical diagnostics, and industrial quality control, thereby supporting advancements in health, science, and environmental protection worldwide.

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Here are a few analogies to describe Thermo Fisher Scientific (TMO):

  • Amazon for scientific labs: Thermo Fisher Scientific provides a vast catalog of everything a scientific laboratory needs, from basic consumables and reagents to advanced analytical instruments and services, similar to how Amazon is a one-stop-shop for a wide array of goods.

  • Home Depot for scientists: Just as Home Depot provides all the tools, materials, and supplies needed for home building and DIY projects, Thermo Fisher Scientific equips scientists with the essential instruments, chemicals, and equipment required for research, diagnostics, and production.

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  • Life Sciences Reagents, Instruments, and Consumables: Offers essential tools for biological and medical research, drug discovery, vaccine production, and disease diagnosis.
  • Analytical Instruments and Software: Provides instruments, consumables, software, and services for laboratory, production line, and field analysis across various research and industrial markets.
  • Specialty Diagnostic Kits (e.g., ImmunoCAP, EliA): Manufactures immunodiagnostic reagent kits and tests for conditions like allergies, asthma, and autoimmune diseases.
  • Culture Media and Collection Systems: Supplies dehydrated and prepared culture media, as well as collection and transport systems for microbiology and diagnostics.
  • Human Leukocyte Antigen (HLA) Typing and Testing: Offers specialized typing and testing services critical for the organ transplant market.
  • Laboratory Refrigerators, Freezers, and Storage Tanks: Provides equipment such as ultralow-temperature freezers, refrigerators, and cryopreservation storage tanks for laboratory samples.
  • General Laboratory Equipment: Includes products for temperature control, sample preparation and preservation, centrifugation, and biological safety cabinets.
  • Laboratory Plastics and Chemicals: Supplies essential consumables like various laboratory plastics products and chemicals.
  • Pharma Services: Offers a range of services supporting pharmaceutical research, development, and manufacturing.

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Major Customers of Thermo Fisher Scientific (TMO)

Thermo Fisher Scientific primarily sells its life sciences solutions, analytical instruments, specialty diagnostics, and laboratory products and services to other companies and institutions rather than directly to individuals. Its major customer categories include:

  • Pharmaceutical and Biotechnology Companies: These customers utilize Thermo Fisher's offerings for biological and medical research, drug discovery, and the production of drugs and vaccines.
  • Academic and Government Research Institutions: Universities, government laboratories, and other research bodies use the company's instruments, reagents, and laboratory products for scientific research across various fields. This category also encompasses other research and industrial markets.
  • Clinical Laboratories and Healthcare Providers: This category includes hospitals, diagnostic centers, and clinical laboratories that rely on Thermo Fisher for specialty diagnostics (e.g., immunodiagnostic tests) as well as laboratory equipment and consumables for patient care and disease diagnosis.

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Marc N. Casper Chairman and Chief Executive Officer

Marc N. Casper has been the Chief Executive Officer of Thermo Fisher Scientific since October 2009 and was elected Chairman of the Board in February 2020. He also served as President from 2009 until March 2026. Casper joined Thermo Fisher in 2001 as President of the Life Sciences sector of Thermo Electron. He was named Senior Vice President in 2003, and in 2005 he assumed responsibility for all of the company's operating divisions. Following the merger that created Thermo Fisher Scientific in 2006, Casper was appointed Executive Vice President and President of its Analytical Technologies business, becoming Chief Operating Officer in 2008. Before joining Thermo Fisher, he served as President, Chief Executive Officer, and a Director of Kendro Laboratory Products. Prior to that, he was President–Americas at clinical diagnostics provider Dade Behring Inc. Casper began his career as a strategy consultant at Bain & Company and later worked for Bain Capital.

Stephen Williamson Senior Vice President and Chief Financial Officer

Stephen Williamson will retire from Thermo Fisher Scientific at the end of March 2026, after serving as Chief Financial Officer since 2015. He joined the company in 2001 as Vice President, European Financial Operations, overseeing integration activities across Europe. In 2004, he moved to the U.S. and held various finance leadership roles for the company's operating businesses, becoming Vice President of Financial Operations for Thermo Fisher Scientific in 2008. Before joining Thermo Fisher, Williamson held finance positions at Honeywell International (formerly AlliedSignal), including Chief Financial Officer for Asia-Pacific in Singapore, and other roles in corporate development and operational finance. He began his career with Price Waterhouse in transaction support and audit.

Gianluca Pettiti President and Chief Operating Officer

Gianluca Pettiti will be promoted to President and Chief Operating Officer, effective March 1, 2026. He has been an Executive Vice President since 2021. Pettiti joined Thermo Fisher Scientific through the acquisition of Life Technologies in 2014.

Michael Shafer Executive Vice President

Michael Shafer, currently an Executive Vice President and President of Biopharma Services since April 2024, will take on an expanded role and report directly to the Chief Executive Officer, effective March 1, 2026.

Lisa P. Britt Senior Vice President and Chief Human Resources Officer

Lisa P. Britt joined Thermo Fisher Scientific in March 2017 as Senior Vice President and Chief Human Resources Officer, where she is responsible for leading the company's global Human Resources strategy and operations. Prior to Thermo Fisher, she spent six years with Nexeo Solutions, a global distributor of plastics and chemicals, serving as Executive Vice President and Chief Human Resources Officer. Before Nexeo, Britt worked for Covidien, a global healthcare products leader, for 13 years, holding several HR senior leadership roles, including Vice President, Global Human Resources.

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The key risks to Thermo Fisher Scientific's business are primarily driven by macroeconomic factors, regulatory and geopolitical developments, and challenges related to its acquisition strategy.

  1. Macroeconomic Headwinds and Funding Challenges: Thermo Fisher Scientific faces significant risk from a challenging macroeconomic environment, including potential cuts in government research funding and cautious spending in academic and government sectors globally. Economic weakness, particularly in China, has dampened demand and contributed to a cautious outlook for the company's growth. Inflationary pressures and fluctuating interest rates can also impact operational costs and profit margins, as well as affect funding for the broader biotech industry, which is a key customer segment for Thermo Fisher. This environment has led to a pullback in global biopharmaceutical spending and cost-cutting measures by the company.

  2. Regulatory Changes and Geopolitical Risks: The company operates in highly regulated industries and is exposed to the risk of adverse regulatory changes, such as U.S. drug price negotiation provisions, which could increase expenses or delay product development. Geopolitical factors, including tariffs and evolving policy changes in key markets like China and the U.S., create uncertainty and can directly impact Thermo Fisher's earnings and financial projections. Furthermore, expanding into emerging markets presents additional risks due to political and financial instability.

  3. Acquisition Integration and Financial Risks: Thermo Fisher Scientific frequently engages in strategic acquisitions to expand its market position and capabilities. However, these acquisitions come with inherent risks, including challenges in successfully integrating acquired businesses and technologies, which can lead to operational difficulties. There are also financial risks associated with these transactions, such as concerns over immediate negative impacts on earnings, increased long-term debt and leverage, and the challenge of generating anticipated returns, especially in a less favorable interest-rate environment.

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Thermo Fisher Scientific (TMO) operates within several significant addressable markets globally and in the U.S. Here are the estimated market sizes for its main product and service segments:

  • Life Sciences Solutions: This segment offers reagents, instruments, and consumables for biological and medical research, drug and vaccine production, and disease diagnosis. The global life science tools market, which encompasses these offerings, was valued at approximately USD 151.62 billion in 2025 and is projected to reach around USD 500.09 billion by 2035. For North America, specifically the U.S., the life science tools market size reached USD 60.00 billion in 2025 and is anticipated to grow to approximately USD 154.33 billion by 2035.
  • Analytical Instruments: Thermo Fisher Scientific's Analytical Instruments segment provides various instruments, consumables, software, and services for laboratory, production line, and field use. The global analytical instrumentation market was valued at USD 58.96 billion in 2025 and is projected to increase to USD 98.68 billion by 2034. North America held approximately 34% of the global analytical instrumentation market share in 2025, with the U.S. market reaching USD 14.6 billion in 2025.
  • Specialty Diagnostics: This segment includes immunodiagnostic reagent kits, allergy and asthma tests, autoimmunity tests, culture media, and human leukocyte antigen typing. The global diagnostic tests market, which includes these specialized tests, was valued at USD 286.36 billion in 2024 and is expected to reach USD 545.94 billion by 2032. The U.S. diagnostic tests market alone accounted for 79% of the North American market in 2024.
  • Laboratory Products and Services: This segment offers a broad range of laboratory equipment such as refrigerators, freezers, and biological safety cabinets, along with laboratory plastics, chemicals, and pharma services. The global laboratory supplies market was valued at USD 48.95 billion in 2025 and is projected to reach USD 103.79 billion by 2034. North America led the global laboratory supplies market with a 38% share in 2024. Additionally, the global laboratory equipment service market was valued at USD 20.51 billion in 2025 and is projected to grow to USD 64.91 billion by 2034.

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Here are the expected drivers of future revenue growth for Thermo Fisher Scientific (TMO) over the next 2-3 years:
  1. Growth in Pharmaceutical and Biotechnology End Markets: Thermo Fisher Scientific anticipates continued strong performance within the pharmaceutical and biotechnology sectors, which collectively represent approximately 60% of its revenue. This segment delivered high single-digit growth in the fourth quarter of 2025 and mid-single-digit growth for the full year 2025. Positive customer sentiment, particularly in biotech, is expected to translate into increased spending and budgets, supporting sustained growth in these critical markets.
  2. Strategic Acquisitions: The company actively pursues strategic acquisitions to expand its offerings and market presence. A significant driver for future revenue is the definitive agreement to acquire Clario, a digital endpoint data provider, which generated approximately $1.5 billion in revenue in 2025. Additionally, the acquisition of Olink, a high-growth business, is projected to close in the second quarter of 2026 and is expected to enhance Thermo Fisher's endpoint solution capabilities.
  3. New Product Launches and Innovation: Investment in research and development (R&D) and the successful launch of innovative products are key to revenue growth. Recent examples of high-impact product launches include the Orbitrap Astro Zoom mass spectrometer and the DynaDrive bioreactor. Thermo Fisher is also leveraging advanced technologies through a new collaboration with OpenAI to promote scientific innovation and a strategic partnership with NVIDIA to advance scientific instrumentation and accelerate laboratory performance.
  4. Expansion of Service Capabilities and Integrated Solutions: Thermo Fisher is enhancing its comprehensive service capabilities, including integrated clinical research and manufacturing, to accelerate drug development for its customers. The company's bioproduction business has demonstrated excellent growth, and its "Accelerator program" has shown strong customer adoption, contributing to increased revenue from its service offerings.
  5. Reshoring and Increased U.S. Manufacturing Capacity: Significant commitments to reshoring manufacturing operations within the United States, including a $2 billion investment in capacity, are expected to drive above-trend growth from 2027 to 2029. This strategic initiative aims to increase Thermo Fisher's market share in new U.S. facilities and bolster domestic medicine production capabilities.

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Share Repurchases

  • Thermo Fisher Scientific authorized a $5 billion share repurchase program in November 2025.
  • The company executed annual share repurchases of $4 billion in 2024 and $3 billion in 2023.

Share Issuance

  • The number of Thermo Fisher Scientific's shares outstanding has shown a declining trend, with a 1.31% decrease in 2025 from 2024, indicating net share repurchases rather than significant share issuance.

Outbound Investments

  • In November 2025, Thermo Fisher acquired Clario for $9 billion, enhancing its clinical trial supply services.
  • The company completed the acquisition of Solventum's Purification & Filtration business for approximately $4.0-$4.1 billion in September 2025, strengthening its bioproduction offerings and expanding into industrial filtration.
  • Other significant acquisitions include Olink for $3.1 billion in 2024 (announced 2023) and PPD for $17.4 billion in 2021, a contract research organization.

Capital Expenditures

  • Thermo Fisher Scientific's capital expenditures increased in each of the last five fiscal years, from $259.1 million in 2021 to $2.2128 billion in 2025.
  • The average annual capital expenditures from 2021 to 2025 were $1.1013 billion.
  • These expenditures are primarily focused on maintaining existing assets and expanding to new property, plant, and equipment.

Better Bets vs. Thermo Fisher Scientific (TMO)

Latest Trefis Analyses

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

TMODHRAILMNBDXWATMedian
NameThermo F.Danaher Agilent .Illumina Becton D.Waters  
Mkt Price572.32192.50139.74196.86152.97382.41194.68
Mkt Cap212.9135.839.430.142.931.441.2
Rev LTM45,19625,1077,2324,39321,3663,77114,299
Op Inc LTM8,2075,1271,5558613,0936042,324
FCF LTM6,7485,4661,0879743,0572642,072
FCF 3Y Avg7,0115,1361,2717392,8954662,083
CFO LTM8,2876,6351,4521,1283,8313902,642
CFO 3Y Avg8,4516,4171,6448913,6306062,637

Growth & Margins

TMODHRAILMNBDXWATMedian
NameThermo F.Danaher Agilent .Illumina Becton D.Waters  
Rev Chg LTM5.4%4.6%9.1%1.3%6.4%26.4%5.9%
Rev Chg 3Y Avg1.1%2.9%1.1%-0.4%4.4%9.0%2.0%
Rev Chg Q6.2%5.5%10.0%4.8%5.2%91.4%5.9%
QoQ Delta Rev Chg LTM1.4%1.3%2.4%1.2%1.1%19.1%1.4%
Op Inc Chg LTM4.7%16.1%9.7%0.2%22.3%-28.6%7.2%
Op Inc Chg 3Y Avg3.7%-3.3%-1.4%10.9%8.2%-9.6%1.2%
Op Mgn LTM18.2%20.4%21.5%19.6%14.5%16.0%18.9%
Op Mgn 3Y Avg17.9%20.0%20.8%11.0%13.2%23.8%19.0%
QoQ Delta Op Mgn LTM-0.0%1.2%0.9%0.8%0.5%-9.3%0.7%
CFO/Rev LTM18.3%26.4%20.1%25.7%17.9%10.3%19.2%
CFO/Rev 3Y Avg19.4%26.5%24.3%20.3%17.8%19.6%19.9%
FCF/Rev LTM14.9%21.8%15.0%22.2%14.3%7.0%15.0%
FCF/Rev 3Y Avg16.1%21.2%18.8%16.8%14.2%15.1%16.5%

Valuation

TMODHRAILMNBDXWATMedian
NameThermo F.Danaher Agilent .Illumina Becton D.Waters  
Mkt Cap212.9135.839.430.142.931.441.2
P/S4.75.45.46.92.08.35.4
P/Op Inc25.926.525.335.013.952.026.2
P/EBIT23.926.923.426.019.050.125.0
P/E31.133.927.935.337.769.934.6
P/CFO25.720.527.126.711.280.626.2
Total Yield3.5%3.7%4.3%2.8%5.4%1.4%3.6%
Dividend Yield0.3%0.7%0.7%0.0%2.8%0.0%0.5%
FCF Yield 3Y Avg3.9%3.4%3.5%3.9%5.6%2.3%3.7%
D/E0.20.20.10.10.40.20.2
Net D/E0.20.20.00.00.40.20.2

Returns

TMODHRAILMNBDXWATMedian
NameThermo F.Danaher Agilent .Illumina Becton D.Waters  
1M Rtn21.9%7.8%10.5%19.4%6.3%7.1%9.2%
3M Rtn22.8%8.0%22.4%56.9%-0.5%22.9%22.6%
6M Rtn-10.3%-19.5%1.2%27.9%-4.3%-4.5%-4.4%
12M Rtn23.1%-2.0%17.9%88.2%9.2%29.4%20.5%
3Y Rtn1.1%-14.6%11.9%7.7%-26.3%33.3%4.4%
1M Excs Rtn21.4%7.2%9.9%18.8%5.7%6.5%8.6%
3M Excs Rtn7.7%1.0%12.4%47.1%-4.8%10.6%9.1%
6M Excs Rtn-17.6%-27.9%-7.3%21.4%-12.1%-11.4%-11.7%
12M Excs Rtn16.9%-15.3%3.8%75.5%-7.4%15.6%9.7%
3Y Excs Rtn-52.3%-71.1%-43.1%-50.3%-82.1%-22.0%-51.3%

Comparison Analyses

Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
Laboratory Products and Biopharma Services23,98423,15723,04122,51114,862
Life Sciences Solutions10,3749,6319,97713,53215,631
Analytical Instruments7,5547,4637,2636,6246,069
Specialty Diagnostics4,6764,5124,4054,7635,659
Elimination of intersegment revenues-2,033-1,885-1,829-2,515-3,010
Total44,55542,87842,85744,91539,211


Operating Income by Segment
$ Mil20252024202320222021
Life Sciences Solutions3,7683,5033,4205,5827,817
Laboratory Products and Biopharma Services3,3503,0903,3582,8721,844
Analytical Instruments1,7361,9551,9081,5071,197
Specialty Diagnostics1,2561,1591,1241,0241,280
Cost of revenues adjustments-64-47-95-46-8
Selling, general and administrative expenses adjustments-2078-59-37-144
Restructuring and other costs-362-379-459-114-197
Amortization of acquisition-related intangible assets-1,730-1,952-2,338-2,395-1,761
Total7,7477,3376,8598,39310,028


Assets by Segment
$ Mil20252024202320222021
Unallocated amounts95,91984,03185,314  
Laboratory Products and Biopharma Services6,4856,1456,35051,28152,639
Life Sciences Solutions3,4462,9823,18621,84822,751
Analytical Instruments3,1702,9442,72610,0199,692
Specialty Diagnostics1,3231,2181,1505,5426,010
Corporate/Other   8,4644,031
Total110,34397,32098,72697,15495,123


Price Behavior

Price Behavior
Market Price$572.32 
Market Cap ($ Bil)212.9 
First Trading Date09/01/1987 
Distance from 52W High-10.3% 
   50 Days200 Days
DMA Price$489.60$528.71
DMA Trendindeterminateup
Distance from DMA16.9%8.2%
 3M1YR
Volatility34.8%30.6%
Downside Capture-88.3756.64
Upside Capture22.2270.40
Correlation (SPY)17.7%33.4%
TMO Betas & Captures as of 6/30/2026

 1M2M3M6M1Y3Y
Beta0.230.310.700.830.820.80
Up Beta-0.410.111.000.980.800.88
Down Beta2.331.951.280.920.930.87
Up Capture-20%-6%29%44%75%30%
Bmk +ve Days11244067140429
Stock +ve Days9203160123370
Down Capture-40%-50%41%101%81%93%
Bmk -ve Days10172358112321
Stock -ve Days12213265129381

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with TMO
TMO34.5%31.9%0.95-
Sector ETF (XLV)22.6%15.8%1.1054.5%
Equity (SPY)18.5%12.7%1.0629.1%
Gold (GLD)17.6%28.1%0.576.5%
Commodities (DBC)35.2%19.1%1.45-14.2%
Real Estate (VNQ)11.6%13.9%0.5525.9%
Bitcoin (BTCUSD)-45.1%42.9%-1.2815.2%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with TMO
TMO2.4%27.6%0.09-
Sector ETF (XLV)6.3%15.0%0.2465.7%
Equity (SPY)12.6%17.1%0.5752.9%
Gold (GLD)16.8%18.4%0.748.0%
Commodities (DBC)9.8%19.5%0.393.1%
Real Estate (VNQ)2.6%18.9%0.0347.8%
Bitcoin (BTCUSD)15.8%53.4%0.4719.8%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with TMO
TMO14.3%26.5%0.53-
Sector ETF (XLV)10.0%16.6%0.4968.6%
Equity (SPY)14.9%17.9%0.7158.0%
Gold (GLD)11.2%16.1%0.578.8%
Commodities (DBC)7.4%17.9%0.3310.5%
Real Estate (VNQ)4.9%20.7%0.2043.4%
Bitcoin (BTCUSD)58.7%66.2%0.9914.2%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date6302026
Short Interest: Shares Quantity5.4 Mil
Short Interest: % Change Since 615202621.1%
Average Daily Volume2.4 Mil
Days-to-Cover Short Interest2.2 days
Basic Shares Quantity372.0 Mil
Short % of Basic Shares1.4%

Earnings Returns History

Updated 7/23/2026
Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
4/23/2026-9.2%-9.3%-12.6%
1/29/2026-2.6%-7.0%-14.3%
10/22/20251.7%-0.1%2.8%
7/23/20259.1%12.8%15.7%
4/23/2025-0.7%-1.7%-8.4%
1/30/20256.8%2.5%-6.9%
10/23/2024-1.7%-6.6%-12.5%
7/24/20244.1%11.4%10.5%
...
SUMMARY STATS   
# Positive141112
# Negative101312
Median Positive1.8%2.5%3.9%
Median Negative-2.7%-2.9%-6.9%
Max Positive9.1%12.8%15.7%
Max Negative-9.2%-9.3%-14.3%
Collapse to Preview
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
4/23/2026-9.2%-9.3%-12.6%
1/29/2026-2.6%-7.0%-14.3%
10/22/20251.7%-0.1%2.8%
7/23/20259.1%12.8%15.7%
4/23/2025-0.7%-1.7%-8.4%
1/30/20256.8%2.5%-6.9%
10/23/2024-1.7%-6.6%-12.5%
7/24/20244.1%11.4%10.5%
4/24/20240.5%-1.0%2.8%
1/31/2024-5.0%-1.2%0.5%
10/25/2023-5.5%-2.9%6.4%
7/26/20230.6%-4.4%-4.5%
4/26/2023-2.8%-0.8%-6.9%
2/1/20233.0%2.2%-3.8%
10/26/2022-2.3%0.6%6.3%
7/28/20222.7%1.0%0.6%
4/28/20227.4%8.2%3.8%
2/2/20221.7%-1.1%-6.7%
10/27/20210.6%4.6%4.1%
7/28/2021-0.4%1.3%3.4%
4/29/2021-4.4%-3.7%-2.7%
2/1/20211.1%-3.4%-9.3%
10/21/20200.8%5.2%-2.4%
7/22/20201.9%1.1%4.3%
SUMMARY STATS   
# Positive141112
# Negative101312
Median Positive1.8%2.5%3.9%
Median Negative-2.7%-2.9%-6.9%
Max Positive9.1%12.8%15.7%
Max Negative-9.2%-9.3%-14.3%

SEC Filings

Expand for More
Report DateFiling DateFiling
03/31/202605/01/202610-Q
12/31/202502/26/202610-K
09/30/202510/31/202510-Q
06/30/202508/01/202510-Q
03/31/202505/02/202510-Q
12/31/202402/20/202510-K
09/30/202411/01/202410-Q
06/30/202408/02/202410-Q
03/31/202405/03/202410-Q
12/31/202302/22/202410-K
09/30/202311/03/202310-Q
06/30/202308/04/202310-Q
03/31/202305/05/202310-Q
12/31/202202/23/202310-K
09/30/202211/04/202210-Q
06/30/202208/05/202210-Q
Collapse to Preview
Report DateFiling DateFiling
03/31/202605/01/202610-Q
12/31/202502/26/202610-K
09/30/202510/31/202510-Q
06/30/202508/01/202510-Q
03/31/202505/02/202510-Q
12/31/202402/20/202510-K
09/30/202411/01/202410-Q
06/30/202408/02/202410-Q
03/31/202405/03/202410-Q
12/31/202302/22/202410-K
09/30/202311/03/202310-Q
06/30/202308/04/202310-Q
03/31/202305/05/202310-Q
12/31/202202/23/202310-K
09/30/202211/04/202210-Q
06/30/202208/05/202210-Q
03/31/202205/06/202210-Q
12/31/202102/24/202210-K
09/30/202111/04/202110-Q
06/30/202108/06/202110-Q
03/31/202105/07/202110-Q
12/31/202002/25/202110-K
09/30/202010/30/202010-Q
06/30/202007/31/202010-Q
03/31/202005/01/202010-Q
12/31/201902/26/202010-K
09/30/201911/01/201910-Q
06/30/201908/02/201910-Q

Insider Activity

Updated 6/30/2026
Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Pettiti, GianlucaPresident & COODirectSell4292026462.66400185,06411,590,018Form
2Shafer, Michael DExecutive Vice PresidentDirectSell3122026499.401,607802,53610,462,407Form
3Casper, Marc NChairman & CEODirectSell3092026514.824,0002,059,26163,798,677Form
4Casper, Marc NChairman & CEODirectSell3052026512.405,0002,561,99463,499,201Form
5Casper, Marc NChairman & CEODirectSell3052026503.105,0002,515,49562,346,718Form
Collapse to Preview
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Pettiti, GianlucaPresident & COODirectSell4292026462.66400185,06411,590,018Form
2Shafer, Michael DExecutive Vice PresidentDirectSell3122026499.401,607802,53610,462,407Form
3Casper, Marc NChairman & CEODirectSell3092026514.824,0002,059,26163,798,677Form
4Casper, Marc NChairman & CEODirectSell3052026512.405,0002,561,99463,499,201Form
5Casper, Marc NChairman & CEODirectSell3052026503.105,0002,515,49562,346,718Form
6Pettiti, GianlucaExecutive Vice PresidentDirectSell2112026541.20400216,48011,231,103Form
7Lagarde, MichelExecutive Vice President & COODirectSell12052025563.5622,04612,424,24447,404,925Form
8Lagarde, MichelExecutive Vice President & COODirectSell12042025583.3932,00018,668,52638,200,419Form
9Lagarde, MichelExecutive Vice President & COODirectSell12042025581.9230,00017,457,60017,154,949Form
10Lowery, Frederick MExecutive Vice PresidentDirectSell12032025581.946,9124,022,3698,360,949Form
11Lowery, Frederick MExecutive Vice PresidentDirectSell12032025597.686,9134,131,7628,587,091Form
12Shafer, Michael DExecutive Vice PresidentDirectSell11262025600.0010,7256,435,00011,238,482Form
13Lagarde, MichelExecutive Vice President & COODirectSell11142025594.424,6382,756,92013,956,928Form
14Britt, Lisa PSr. VP and Chief HR OfficerDirectSell11142025588.261,058622,1367,698,758Form
15Pettiti, GianlucaExecutive Vice PresidentDirectSell11122025580.002,9751,725,50012,268,289Form
16Britt, Lisa PSr. VP and Chief HR OfficerDirectSell11102025571.6210,2255,844,8508,085,502Form
17Casper, Marc NChairman & CEODirectSell10282025566.107,2504,104,24264,401,093Form
18Pettiti, GianlucaExecutive Vice PresidentDirectSell10282025574.15400229,66012,144,549Form
19Casper, Marc NChairman & CEODirectSell10282025573.5417,1049,809,86265,247,446Form
20Casper, Marc NChairman & CEODirectSell9092025500.50400200,20156,938,308Form
21Holmes, Joseph RVP & Chief Accounting OfficerDirectSell9022025492.63385189,6621,142,396Form
22Casper, Marc NChairman & CEODirectSell8262025500.9610,0005,009,58657,697,217Form
23Casper, Marc NChairman & CEODirectSell8212025500.04295147,51257,591,633Form
24Casper, Marc NChairman & CEODirectSell8212025500.17201100,53457,606,057Form
25Casper, Marc NChairman & CEODirectSell8072025454.458,0003,635,56752,340,183Form
26Casper, Marc NChairman & CEODirectSell8072025451.8210,0004,518,21652,037,931Form
27Pettiti, GianlucaExecutive Vice PresidentDirectSell7282025479.98400191,99210,735,677Form

Investor Activity (13F)

Updated Jul 24, 2026
13F holdings as of Mar 31, 2026 (Q1 2026)

Active managers (13F portfolio over $250M, at least 3 holdings) with a position over $5M that is either over 10% of their portfolio or held in a concentrated book of 50 or fewer total positions. Index/ETF, sovereign, bank, community-bank and charitable/donor-advised filers are excluded.

Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Arvin Capital Management LP$54.9 Mil12.8%23ADD +64.7%13F
Spinecap SAS$34.2 Mil12.5%15Hold13F
Cryder Capital Partners LLP$185.2 Mil12.1%10Hold13F
C Partners Holding GmbH$32.1 Mil10.1%7ADD +20.2%13F
Lindsell Train Ltd$303.4 Mil9.7%27TRIM -10.5%13F
Tri Locum Partners LP$65.1 Mil9.1%17New13F
Unisphere Establishment$1.0 Bil8.5%50ADD +5.1%13F
EdgePoint Investment Group Inc.$943.2 Mil7.6%37ADD +38.5%13F
Caledonia Investments PLC$55.0 Mil6.4%15Hold13F
Route One Investment Company, L.P.$127.2 Mil5.6%18Hold13F
Wilson Asset Management (International) PTY LTD$18.7 Mil5.3%43ADD +14.3%13F
DKRT Investments Corp.$20.6 Mil5.2%48New13F
Rempart Asset Management Inc.$23.3 Mil4.9%36TRIM -8.7%13F
America First Investment Advisors, LLC$26.0 Mil4.8%41Hold13F
Atle Fund Management AB$14.4 Mil4.7%39TRIM -23.2%13F
Longview Partners (Guernsey) LTD$325.8 Mil4.6%25TRIM -22.0%13F
Weitz Investment Management, Inc.$59.5 Mil4.2%49TRIM -10.3%13F
Bristol Gate Capital Partners Inc.$63.4 Mil4.1%31TRIM -6.5%13F
Jia Investment Alliance PTE. LTD.$38.7 Mil4.1%24Hold13F
Southpoint Capital Advisors LP$196.6 Mil4.0%41ADD +300.0%13F
Dundas Partners LLP$47.9 Mil3.8%49Hold13F
Local Pensions Partnership Investment Ltd$168.1 Mil3.6%32TRIM -5.1%13F
Eldred Rock Partners, LLC$14.0 Mil3.6%31New13F
Mirova US LLC$302.3 Mil3.4%42Hold13F
Generation Investment Management LLP$380.2 Mil3.4%29TRIM -30.4%13F
Active ManagerValue% of PortfolioTotal PositionsQoQFiling
D1 Capital Partners L.P.$356.4 Mil3.2%44New13F
Tri Locum Partners LP$65.1 Mil9.1%17New13F
Spear Holdings RSC Ltd$29.8 Mil3.2%17New13F
PBCay One RSC Ltd$29.8 Mil3.2%17New13F
MKP Capital Management, L.L.C.$29.5 Mil1.0%19New13F
DKRT Investments Corp.$20.6 Mil5.2%48New13F
Petrus Trust Company, LTA$17.2 Mil1.9%27New13F
Eldred Rock Partners, LLC$14.0 Mil3.6%31New13F
Cincinnati Specialty Underwriters Insurance CO$7.8 Mil1.9%46New13F
Southpoint Capital Advisors LP$196.6 Mil4.0%41ADD +300.0%13F
Retail Employees Superannuation Pty Ltd as trustee for Retail Employees Superannuation Trust$21.9 Mil3.3%28ADD +149.0%13F
Arvin Capital Management LP$54.9 Mil12.8%23ADD +64.7%13F
Nuance Investments, LLC$14.9 Mil2.1%43ADD +44.3%13F
EdgePoint Investment Group Inc.$943.2 Mil7.6%37ADD +38.5%13F
C Partners Holding GmbH$32.1 Mil10.1%7ADD +20.2%13F
Wilson Asset Management (International) PTY LTD$18.7 Mil5.3%43ADD +14.3%13F
Glenview Capital Management, LLC$123.1 Mil3.3%41ADD +11.9%13F
Skye Global Management LP$58.2 Mil1.3%44ADD +9.7%13F
Unisphere Establishment$1.0 Bil8.5%50ADD +5.1%13F
Active ManagerValue% of PortfolioTotal PositionsQoQAs OfFiling
BlueSpruce Investments, LP$230.6 Mil5.9%9ExitedDec 31, 202513F
Third Point LLC$29.0 Mil0.4%44ExitedDec 31, 202513F
Sector Gamma AS$12.6 Mil2.9%36ExitedDec 31, 202513F
J. Stern & Co. LLP$27.0 Mil2.6%49TRIM -99.8%Mar 31, 202613F
Generation Investment Management LLP$380.2 Mil3.4%29TRIM -30.4%Mar 31, 202613F
Atle Fund Management AB$14.4 Mil4.7%39TRIM -23.2%Mar 31, 202613F
Longview Partners (Guernsey) LTD$325.8 Mil4.6%25TRIM -22.0%Mar 31, 202613F
Lindsell Train Ltd$303.4 Mil9.7%27TRIM -10.5%Mar 31, 202613F
Weitz Investment Management, Inc.$59.5 Mil4.2%49TRIM -10.3%Mar 31, 202613F
Rempart Asset Management Inc.$23.3 Mil4.9%36TRIM -8.7%Mar 31, 202613F
Haverford Financial Services, Inc.$5.2 Mil1.5%46TRIM -7.9%Mar 31, 202613F
Bristol Gate Capital Partners Inc.$63.4 Mil4.1%31TRIM -6.5%Mar 31, 202613F
Local Pensions Partnership Investment Ltd$168.1 Mil3.6%32TRIM -5.1%Mar 31, 202613F
Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Unisphere Establishment$1.0 Bil8.5%50ADD +5.1%13F
EdgePoint Investment Group Inc.$943.2 Mil7.6%37ADD +38.5%13F
Generation Investment Management LLP$380.2 Mil3.4%29TRIM -30.4%13F
D1 Capital Partners L.P.$356.4 Mil3.2%44New13F
Longview Partners (Guernsey) LTD$325.8 Mil4.6%25TRIM -22.0%13F
Lindsell Train Ltd$303.4 Mil9.7%27TRIM -10.5%13F
Mirova US LLC$302.3 Mil3.4%42Hold13F
Southpoint Capital Advisors LP$196.6 Mil4.0%41ADD +300.0%13F
Cryder Capital Partners LLP$185.2 Mil12.1%10Hold13F
Local Pensions Partnership Investment Ltd$168.1 Mil3.6%32TRIM -5.1%13F
Route One Investment Company, L.P.$127.2 Mil5.6%18Hold13F
Glenview Capital Management, LLC$123.1 Mil3.3%41ADD +11.9%13F
Tri Locum Partners LP$65.1 Mil9.1%17New13F
Bristol Gate Capital Partners Inc.$63.4 Mil4.1%31TRIM -6.5%13F
Weitz Investment Management, Inc.$59.5 Mil4.2%49TRIM -10.3%13F
Skye Global Management LP$58.2 Mil1.3%44ADD +9.7%13F
Caledonia Investments PLC$55.0 Mil6.4%15Hold13F
Arvin Capital Management LP$54.9 Mil12.8%23ADD +64.7%13F
Dundas Partners LLP$47.9 Mil3.8%49Hold13F
Jia Investment Alliance PTE. LTD.$38.7 Mil4.1%24Hold13F
Spinecap SAS$34.2 Mil12.5%15Hold13F
C Partners Holding GmbH$32.1 Mil10.1%7ADD +20.2%13F
Spear Holdings RSC Ltd$29.8 Mil3.2%17New13F
PBCay One RSC Ltd$29.8 Mil3.2%17New13F
MKP Capital Management, L.L.C.$29.5 Mil1.0%19New13F

TMO Trade Sentinel


Stock Conviction

Constructive

CONVICTION RATIONALE

Conviction is constructive, based on management's strong record of execution and a raised full-year outlook for 6% to 8% reported revenue growth. While Q1 organic growth was soft, the company's core pharma and biotech end market remains solid. The thesis hinges on management delivering the guided re-acceleration in coming quarters.

STOCK ARCHETYPE
Diversified Consumables & Capital Equipment Supplier

(Volume of R&D/Clinical Activity) x (Mix of Consumables, Instruments, & Services) x (Price) Mix shift towards higher-margin segments like Life Sciences Solutions and Specialty Diagnostics, combined with operational efficiencies from the PPI Business System.

Looking for high-conviction positions with a better risk/reward profile? See what's currently in the Trefis High Quality Portfolio.
INVESTMENT THESIS
Can management deliver its guided re-acceleration after a soft quarter?

Evidence suggests a temporary slowdown, with a credible path to re-acceleration backed by a strong execution track record.

Mechanism: Achieving the raised full-year guidance of 3% to 4% organic growth and integrating the Clario acquisition should drive 8% to 10% adjusted EPS growth.
Supporting Evidence:
  • Full-year 2026 revenue guidance was raised to $47.3 billion - $48.1 billion.
  • The clinical research business delivered strong authorizations growth in Q1 2026.
  • The core pharma and biotech end market grew mid-single-digits in Q1 2026.
  • Inventory grew slower than revenue, a positive sign for working capital.
PRIMARY RISK
A Cyclical Slowdown Deepens

The 1% organic growth in Q1 2026, which trailed peers, could signal a broader-than-expected slowdown, making the guided full-year recovery of 3% to 4% unattainable.

Mechanism: A miss on Q2 organic growth guidance would confirm the slowdown is not temporary.
Supporting Evidence:
  • Q1 2026 organic revenue growth was 1%, decelerating from 3% in Q4 2025.
  • The academic and government end market declined by low single digits in Q1.
  • Diagnostics and Health Care revenue declined mid-single digits in Q1.
  • Net debt to EBITDA is elevated at 3.41x after a recent acquisition.
Key KPI Watchlist
KPI Status Rationale
Pharma and Biotech End Market GrowthMid-single-digit growth in Q1 2026 - DeceleratingGrowth in the company's largest end market moderated in the first quarter of 2026, returning to the mid-single-digit pace seen in Q3 2025 after a stronger high single-digit performance in Q4 2025.
Overall Organic Revenue Growth1% organic revenue growth in Q1 2026 - DeceleratingManagement attributed the significant slowdown to temporary factors, including one fewer selling day which impacted growth by approximately 1 percentage point, and the timing of revenue phasing in the Pharma Services business.
Clinical Research Authorizations GrowthStrong (Q1 2026)Indicates future revenue growth for the clinical research business, as authorizations represent new business signed but not yet converted to revenue.
Inventory-vs-Revenue Growth Divergence-1 percentage points (Q2 2026)A negative divergence indicates that inventory is growing slower than revenue, which is a positive sign for working capital management and demand fulfillment.
Core Investment Debate

Temporary Stumble vs. Faltering Growth Engine

BULL VIEW

Bulls see the Q1 slowdown as a one-off caused by selling days and timing, pointing to raised full-year guidance for 6% to 8% reported growth as proof of underlying strength.

CORE TENSION

Can strong pharma/biotech demand and the Clario acquisition offset the 1% Q1 organic growth and weakness in academic markets to meet the raised full-year guidance?


PREVAILING SENTIMENT
CAUTIOUSLY BULLISH

The latest evidence favors the bull view. Management's strong say-do record and the specific, non-recurring explanations for the Q1 miss lend credibility to the guided recovery.

BEAR VIEW

Bears see the 1% Q1 organic growth, which trailed peers, as a sign of market share loss or a deeper cyclical slowdown that makes the guided re-acceleration unlikely.

Next 6 months: Risks and Catalysts
Timeline Event & Metric To Watch
8/6/2026
Peer Reports Signal Sector Weakness
Watch: Commentary from BDX or A on academic/government spending, China, or pharma capital budgets.
8/18/2026
Peer Earnings Report
Watch: Peer Agilent Technologies (A) is scheduled to report earnings.
10/19/2026
Peer Earnings Report
Watch: Peer Danaher (DHR) is scheduled to report earnings.
10/20/2026
Persistent China and Academic Headwinds
Watch: Updated full-year guidance and specific growth figures for the academic/government segment and China region.
10/20/2026
Inflation Erodes Margin Guidance
Watch: Reported gross and operating margins versus guidance, and commentary on success of PPI Business System productivity initiatives.
Key Events in Last 6 Months
Date Event Stock Impact
2026-06-01
Expands Orbitrap Platform at ASMS
Details: The company expanded its suite of Thermo Scientific™ Orbitrap™ mass spectrometry platforms at the American Society for Mass Spectrometry (ASMS) Conference.
-2.1%
$492.02 -> $481.60
2026-05-20
Hosts Investor Day
Details: The company hosted its Investor Day, where leadership highlighted industry leadership, growth outlook, and long-term value creation.
+0.3%
$447.36 -> $448.92
2026-04-23
Reports Q1 2026 Results
Details: First quarter revenue grew 6% to $11.01 billion and adjusted EPS grew 6% to $5.44. The stock reacted negatively, with a two-day decline of -9.0%.
-8.6%
$513.47 -> $469.24
2026-03-24
Clario Acquisition Completed
Details: The acquisition of Clario Holdings, Inc., a provider of endpoint data solutions for clinical trials, was completed for approximately $9 billion.
+2.6%
$477.64 -> $490.28
2026-02-25
Dividend Increased Ten Percent
Details: The Board of Directors authorized a quarterly cash dividend of $0.47 per common share, reflecting a 10% increase over the previous dividend.
+0.9%
$514.58 -> $519.09
2026-01-29
Reports Q4 2025, Cautious Guidance
Details: The company delivered a Q4 earnings beat but provided cautious 2026 guidance, with revenue projected at $46.3B-$47.2B. The stock reacted negatively, falling -5.0% over two days.
-4.8%
$606.81 -> $577.46
Risk Management
Position Sizing

2% - 4%

REDUCED POSITION

Sizing is volatility-based: TMO trades at roughly 33% annualized options-implied volatility versus about 15% for the S&P 500 (2.2x the market), around the 88th percentile of its own trailing year. A 2% - 4% position keeps a single-name swing of that size within a diversified portfolio's risk budget.

Diversification Alternatives
DHR - Danaher
Higher-Margin Peer

Danaher operates with a substantially higher gross margin of 58.9% versus Thermo Fisher's 40.8%, suggesting a different, potentially more profitable business mix.

Core Thesis: An investment in a highly profitable life sciences peer that also saw encouraging signs of stabilization in its end markets.
A - a business partner
Focused Instrument Play

Agilent offers more concentrated exposure to the analytical instruments market, where it reported market-leading low double-digit growth in key product lines like LCMS.

Core Thesis: A play on a more focused competitor that is demonstrating strong growth in its core instrument franchises.
How Is The Market Pricing TMO?

A highly diversified 'picks and shovels' provider for the entire life sciences ecosystem, from basic research to commercial drug production.

Thermo Fisher operates as an essential supplier to a wide range of scientific and medical end markets. Its growth is tied to the overall activity and R&D spending in pharma, biotech, and healthcare. The company's strategy relies on high-impact innovation, its 'trusted partner status' with customers, and a disciplined M&A approach to add complementary capabilities.

What will confirm the thesis

News of increased government research funding (e.g., NIH budgets), strong R&D spending from large pharma, or a rebound in biotech funding would confirm the thesis.

What will damage the thesis

A significant downturn in customer capital spending, prolonged government shutdowns delaying funding, or major regulatory changes that slow the drug development process would damage the thesis.

Noise: Real but irrelevant to thesis

Quarterly fluctuations in instrument sales due to customer budget cycles or single-product news from smaller competitors.

Repricing Catalyst

Successful integration of the newly acquired Clario business, which enhances the high-growth clinical research offering, and a potential stabilization or recovery in the currently muted academic and government end markets.

What TMO Makes & Who Pays
TTM figures based on fiscal year 2025 filings (the latest reported segment data)
Laboratory Products and Biopharma Services
$24.0B TTM (54% of Total) · 14% Margin
What It Is

Sells lab consumables, equipment, and chemicals, and offers outsourced services for drug development, clinical research, clinical trials, and commercial drug manufacturing. It serves pharmaceutical, biotechnology, academic, government, industrial, and clinical laboratory markets.

Who Pays & How

Pharmaceutical and biotech companies pay for a comprehensive offering of outsourced services for the entire spectrum of drug development and manufacturing, enabling them to be more innovative, productive, and cost-efficient.

Transactional sales of products and service-based contracts.
Competition
Danaher (DHR), Becton Dickinson (BDX)
Competitors include a broad range of manufacturers, third-party distributors, and service providers. Success depends on factors like technical performance, product differentiation, and customer service.
A unique combination of self-manufactured and sourced products, an extensive service offering, and an unparalleled commercial engine that provides purchasing convenience and enables customers to focus on their core activities.
Life Sciences Solutions
$10.4B TTM (23% of Total) · 36% Margin
What It Is

Provides reagents, instruments, and consumables used in biological and medical research, discovery and production of new drugs and vaccines, and disease diagnosis. Customers are in pharmaceutical, biotechnology, agricultural, clinical, healthcare, academic, and government markets.

Who Pays & How

Pharma and biotech customers pay for solutions for the production of biologics, including upstream cell culture and downstream purification, to improve quality and efficiency in their workflows.

Transactional sales of products and consumables.
Competition
Danaher (DHR), Illumina (ILMN)
Competitors may adapt more quickly to new technologies. Success depends on technological innovation and evolving industry standards.
An extensive portfolio of reagents, instruments, and consumables, combined with high-impact innovation and a trusted partner status with customers.
Analytical Instruments
$7.6B TTM (17% of Total) · 23% Margin
What It Is

Provides instruments, consumables, software, and services for a range of applications including chromatography, mass spectrometry, chemical analysis, and electron microscopy. Customers are in pharmaceutical, biotechnology, academic, government, environmental, industrial, and clinical laboratory markets.

Who Pays & How

Research and industrial customers pay for analytical instrumentation for organic and inorganic sample analysis, as well as leading research tools for life sciences, materials sciences, and semiconductor markets.

Transactional sales of instruments and related consumables and software.
Competition
Agilent Technologies (A), Waters (WAT)
Competition is characterized by changing technology and customer demands that require continuing research and development.
A broad offering of instruments supported by a reputation for technical performance, product reliability, and a global sales and service network.
Specialty Diagnostics
$4.7B TTM (10% of Total) · 27% Margin
What It Is

Offers diagnostic test kits, reagents, culture media, and instruments to customers in healthcare, clinical, pharmaceutical, industrial, and food safety laboratories. Products include tests for allergy, asthma, autoimmune diseases, and organ transplant diagnostics.

Who Pays & How

Healthcare and clinical laboratories pay for products that increase the speed and accuracy of diagnoses, which improves patient care in a more cost-efficient manner.

Transactional sales of diagnostic kits, reagents, and instruments.
Competition
Becton Dickinson (BDX)
The company faces aggressive and able competition in virtually all markets served.
A wide range of diagnostic test kits and complete blood-test systems that support clinical diagnosis and monitoring, delivered through a dedicated healthcare market channel.
TMO Evolution: Price Return by Era
· Pre-2021 Foundational Growth
Prior to 2021, the company established its four core segments, with Laboratory Products and Biopharma Services as the largest revenue contributor, followed by Life Sciences Solutions.
2021-2022 · Pandemic-Driven Surge (2021-2022)
+17%
The Life Sciences Solutions segment saw a dramatic revenue increase, peaking at $15,631 million in 2021, likely driven by pandemic-related demand for research, vaccine, and diagnostic tools. Total company revenue peaked in 2022 at $44,915 million.
2023-2025 · Post-Pandemic Normalization and Strategic M&A (2023-Present)
+6%
Life Sciences Solutions revenue normalized downwards from its 2021 peak, while the Laboratory Products and Biopharma Services segment continued its steady growth trajectory, solidifying its position as the largest segment. The company has focused on strategic acquisitions like Clario to bolster its clinical research capabilities.
Market Is In Wait-and-See Mode
Price structure is showing early stress, with SMA alignment beginning to break down. Relative to SPY: Decisively outperforming and improving. Potential evidence of active institutional rotation. Volume and momentum are strongly confirming. The institutional accumulation is evident and momentum is accelerating. Earnings history is mildly cautionary. The reaction or drift are negative, and the market is beginning to push back on the thesis.
① Structure
-1
Structural pillar score (-4 to +4). Driven by trend regime, SMA cross events, proximity to 52W high, and relative strength vs SPY.
② Volume / Momentum
+4
Volume/Momentum pillar score (-4 to +4). Driven by institutional footprint score, OBV divergence, and momentum character.
③ Catalyst
-1
Catalyst pillar score (-4 to +4). Driven by earnings day reaction, 20D post-earnings drift, and post-earnings volume character.
Combined Score
2 / 12
1 Price Structure & Trend Potential Bottoming · Death Cross
2 Momentum Accelerating
3 Relative Strength vs. SPY Strong Outperformance
4 Institutional Footprint & Volume Strong Accumulation
5 Volatility Normal
6 Key Price Levels Range · Vol Rising
7 Earnings Reaction History Inconsistent
8 How the Verdict Is Derived Three Pillars
Core Cache Last Updated: 7/23/2026