Thermo Fisher Scientific (TMO)


Market Price (8/7/2026): $576.83 | Market Cap: $214.0 BilInvestor Relations Sector: Health Care | Industry: Life Sciences Tools & Services

Thermo Fisher Scientific (TMO)


Market Price (8/7/2026): $576.83
Market Cap: $214.0 Bil
Sector: Health Care
Industry: Life Sciences Tools & Services

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

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Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 19%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 16%, CFO LTM is 9.0 Bil, FCF LTM is 7.3 Bil

Stock buyback support
Stock Buyback 3Y Total is 11 Bil

Low stock price volatility
Vol 12M is 31%

Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Advanced Diagnostics, Show more.

Weak multi-year price returns
2Y Excs Rtn is -48%, 3Y Excs Rtn is -61%

Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 24x, P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 24x, P/EPrice/Earnings or Price/(Net Income) is 31x

Key risks
TMO key risks include [1] dampened demand from potential cuts in government research funding and new tariffs, Show more.

0 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 19%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 16%, CFO LTM is 9.0 Bil, FCF LTM is 7.3 Bil
1 Stock buyback support
Stock Buyback 3Y Total is 11 Bil
2 Low stock price volatility
Vol 12M is 31%
3 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Advanced Diagnostics, Show more.
4 Weak multi-year price returns
2Y Excs Rtn is -48%, 3Y Excs Rtn is -61%
5 Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 24x, P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 24x, P/EPrice/Earnings or Price/(Net Income) is 31x
6 Key risks
TMO key risks include [1] dampened demand from potential cuts in government research funding and new tariffs, Show more.

TMO in ETFs

Weight = TMO's share of each fund

SPY0.33%
VOO0.29%
IVV0.33%
VTI0.27%
ITOT0.29%
IWB0.31%
RSP0.23%
VTV0.70%
+24 more covered ETFs

Valuation & Metrics

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Updated on 8/1/2026

Thermo Fisher Scientific (TMO) stock has gained about 20% since 4/30/2026 because of the following key factors:

1. Thermo Fisher Scientific's stock gained significantly following its robust fiscal Q2 2026 earnings report, released on July 23, 2026, which covered the period ending June 30, 2026. The company reported adjusted earnings per share (EPS) of $6.03, exceeding the consensus estimate of $5.71 by $0.32. Additionally, revenue for fiscal Q2 2026 reached $11.99 billion, surpassing the consensus estimate of $11.71 billion and representing a 10.5% year-over-year increase.

2. Management raised its full-year fiscal 2026 guidance, demonstrating strong confidence in the company's future performance. Following the better-than-expected fiscal Q2 results, Thermo Fisher Scientific increased its full-year revenue outlook to a range of $47.4 billion to $48.1 billion and adjusted its EPS guidance to $24.93–$25.33. This positive outlook was a significant catalyst for the stock's upward movement.

Show more
Updated on 8/1/2026

Thermo Fisher Scientific (TMO) stock has gained about 20% since 4/30/2026 because of the following key factors:

1. Thermo Fisher Scientific's stock gained significantly following its robust fiscal Q2 2026 earnings report, released on July 23, 2026, which covered the period ending June 30, 2026. The company reported adjusted earnings per share (EPS) of $6.03, exceeding the consensus estimate of $5.71 by $0.32. Additionally, revenue for fiscal Q2 2026 reached $11.99 billion, surpassing the consensus estimate of $11.71 billion and representing a 10.5% year-over-year increase.

2. Management raised its full-year fiscal 2026 guidance, demonstrating strong confidence in the company's future performance. Following the better-than-expected fiscal Q2 results, Thermo Fisher Scientific increased its full-year revenue outlook to a range of $47.4 billion to $48.1 billion and adjusted its EPS guidance to $24.93–$25.33. This positive outlook was a significant catalyst for the stock's upward movement.

3. Positive analyst sentiment and increased price targets further fueled the stock's appreciation. Post-earnings, numerous analysts reiterated positive ratings and raised their price targets for TMO. For instance, Barclays increased its target price from $625.00 to $650.00, while RBC Capital raised its price target from $490 to $580. The consensus among 24 brokerages remained a "Moderate Buy," with an average 1-year price objective rising to approximately $634.92, implying a 13% potential upside from the July 27, 2026 closing price.

4. Strategic capital allocation and product innovations contributed to investor confidence. During fiscal Q2 2026, Thermo Fisher Scientific announced a planned $1 billion share repurchase program, to be funded by the pending divestiture of its microbiology business. The company also launched its InstaFlux media-on-demand workflow for food microbiology labs and expanded an advanced-therapy partnership with Arcturus, underscoring ongoing innovation and strategic growth initiatives. These actions reinforced the company's commitment to shareholder value and long-term growth.

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Stock Movement Drivers

Fundamental Drivers

The 21.2% change in TMO stock from 4/30/2026 to 8/6/2026 was primarily driven by a 15.7% change in the company's P/E Multiple.
(LTM values as of)43020268062026Change
Stock Price ($)478.48580.0221.2%
Change Contribution By: 
Total Revenues ($ Mil)44,55546,3364.0%
Net Income Margin (%)15.0%15.0%-0.1%
P/E Multiple26.730.915.7%
Shares Outstanding (Mil)3743710.8%
Cumulative Contribution21.2%

LTM = Last Twelve Months as of date shown

Market Drivers

4/30/2026 to 8/6/2026
ReturnCorrelation
TMO21.2% 
Market (SPY)6.9%-2.1%
Sector (XLV)12.6%47.3%

Fundamental Drivers

The 0.4% change in TMO stock from 1/31/2026 to 8/6/2026 was primarily driven by a 5.9% change in the company's Total Revenues ($ Mil).
(LTM values as of)13120268062026Change
Stock Price ($)577.46580.020.4%
Change Contribution By: 
Total Revenues ($ Mil)43,73546,3365.9%
Net Income Margin (%)15.0%15.0%0.1%
P/E Multiple33.230.9-7.0%
Shares Outstanding (Mil)3783711.9%
Cumulative Contribution0.4%

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2026 to 8/6/2026
ReturnCorrelation
TMO0.4% 
Market (SPY)11.4%23.9%
Sector (XLV)6.7%45.8%

Fundamental Drivers

The 24.5% change in TMO stock from 7/31/2025 to 8/6/2026 was primarily driven by a 14.2% change in the company's P/E Multiple.
(LTM values as of)73120258062026Change
Stock Price ($)465.98580.0224.5%
Change Contribution By: 
Total Revenues ($ Mil)42,89846,3368.0%
Net Income Margin (%)15.2%15.0%-1.0%
P/E Multiple27.030.914.2%
Shares Outstanding (Mil)3783711.9%
Cumulative Contribution24.5%

LTM = Last Twelve Months as of date shown

Market Drivers

7/31/2025 to 8/6/2026
ReturnCorrelation
TMO24.5% 
Market (SPY)22.6%26.3%
Sector (XLV)27.7%54.0%

Fundamental Drivers

The 6.7% change in TMO stock from 7/31/2023 to 8/6/2026 was primarily driven by a 9.3% change in the company's Net Income Margin (%).
(LTM values as of)73120238062026Change
Stock Price ($)543.42580.026.7%
Change Contribution By: 
Total Revenues ($ Mil)43,80746,3365.8%
Net Income Margin (%)13.8%15.0%9.3%
P/E Multiple34.830.9-11.3%
Shares Outstanding (Mil)3863714.0%
Cumulative Contribution6.7%

LTM = Last Twelve Months as of date shown

Market Drivers

7/31/2023 to 8/6/2026
ReturnCorrelation
TMO6.7% 
Market (SPY)73.8%42.6%
Sector (XLV)28.3%61.8%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
TMO Return44%-17%-3%-2%12%-0%26%
Peers Return28%-15%-9%1%-2%13%10%
S&P 500 Return27%-19%24%23%16%13%106%

Monthly Win Rates [3]
TMO Win Rate75%42%58%50%50%50% 
Peers Win Rate73%40%43%47%48%55% 
S&P 500 Win Rate75%42%67%75%67%50% 

Max Drawdowns [4]
TMO Max Drawdown-15%-27%-29%-20%-36%-31% 
Peers Max Drawdown-20%-33%-34%-20%-37%-27% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: DHR, A, ILMN, BDX, WAT. See TMO Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 8/6/2026 (YTD)

How Low Can It Go

EventTMOS&P 500
2025 US Tariff Shock
  % Loss-25.8%-18.8%
  % Gain to Breakeven34.7%23.1%
  Time to Breakeven131 days79 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-24.4%-9.5%
  % Gain to Breakeven32.2%10.5%
  Time to Breakeven124 days24 days
2023 SVB Regional Banking Crisis
  % Loss-11.5%-6.7%
  % Gain to Breakeven13.0%7.1%
  Time to Breakeven56 days31 days
2022 Inflation Shock & Fed Tightening
  % Loss-24.4%-24.5%
  % Gain to Breakeven32.2%32.4%
  Time to Breakeven1190 days427 days
2020 COVID-19 Crash
  % Loss-24.8%-33.7%
  % Gain to Breakeven33.0%50.9%
  Time to Breakeven35 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-15.7%-19.2%
  % Gain to Breakeven18.6%23.8%
  Time to Breakeven44 days105 days

Compare to DHR, A, ILMN, BDX, WAT

In The Past

Thermo Fisher Scientific's stock fell -25.8% during the 2025 US Tariff Shock. Such a loss loss requires a 34.7% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventTMOS&P 500
2025 US Tariff Shock
  % Loss-25.8%-18.8%
  % Gain to Breakeven34.7%23.1%
  Time to Breakeven131 days79 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-24.4%-9.5%
  % Gain to Breakeven32.2%10.5%
  Time to Breakeven124 days24 days
2022 Inflation Shock & Fed Tightening
  % Loss-24.4%-24.5%
  % Gain to Breakeven32.2%32.4%
  Time to Breakeven1190 days427 days
2020 COVID-19 Crash
  % Loss-24.8%-33.7%
  % Gain to Breakeven33.0%50.9%
  Time to Breakeven35 days140 days
2011 US Debt Ceiling Crisis & European Contagion
  % Loss-25.5%-17.9%
  % Gain to Breakeven34.3%21.8%
  Time to Breakeven411 days123 days
2008-2009 Global Financial Crisis
  % Loss-51.1%-53.4%
  % Gain to Breakeven104.6%114.4%
  Time to Breakeven888 days1085 days

Compare to DHR, A, ILMN, BDX, WAT

In The Past

Thermo Fisher Scientific's stock fell -25.8% during the 2025 US Tariff Shock. Such a loss loss requires a 34.7% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Thermo Fisher Scientific (TMO)

Thermo Fisher Scientific (TMO) is a global leader in providing an extensive range of scientific products and services. The company essentially equips scientists, researchers, and clinicians with the essential tools and support necessary for scientific discovery, diagnostics, and production across various industries. Operating through distinct segments, Thermo Fisher addresses critical needs within the global scientific and healthcare communities.

The company's core offerings include life sciences solutions, providing reagents, instruments, and consumables vital for biological and medical research, drug and vaccine development, and disease diagnosis. They also specialize in analytical instruments, software, and services used for precise measurement and analysis in laboratories and industrial settings. Furthermore, Thermo Fisher supplies specialty diagnostic products, such as immunodiagnostic kits for allergy, asthma, and autoimmunity testing, alongside a broad portfolio of laboratory products like refrigerators, centrifuges, chemicals, and comprehensive pharmaceutical services.

Thermo Fisher's diverse customer base primarily consists of pharmaceutical and biotechnology companies, academic and government research institutions, clinical laboratories, hospitals, and environmental organizations. Their products and services are indispensable for a wide array of applications, spanning cutting-edge scientific research, new drug development, routine clinical diagnostics, and industrial quality control, thereby supporting advancements in health, science, and environmental protection worldwide.

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Here are a few analogies to describe Thermo Fisher Scientific (TMO):

  • Amazon for scientific labs: Thermo Fisher Scientific provides a vast catalog of everything a scientific laboratory needs, from basic consumables and reagents to advanced analytical instruments and services, similar to how Amazon is a one-stop-shop for a wide array of goods.

  • Home Depot for scientists: Just as Home Depot provides all the tools, materials, and supplies needed for home building and DIY projects, Thermo Fisher Scientific equips scientists with the essential instruments, chemicals, and equipment required for research, diagnostics, and production.

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  • Life Sciences Reagents, Instruments, and Consumables: Offers essential tools for biological and medical research, drug discovery, vaccine production, and disease diagnosis.
  • Analytical Instruments and Software: Provides instruments, consumables, software, and services for laboratory, production line, and field analysis across various research and industrial markets.
  • Specialty Diagnostic Kits (e.g., ImmunoCAP, EliA): Manufactures immunodiagnostic reagent kits and tests for conditions like allergies, asthma, and autoimmune diseases.
  • Culture Media and Collection Systems: Supplies dehydrated and prepared culture media, as well as collection and transport systems for microbiology and diagnostics.
  • Human Leukocyte Antigen (HLA) Typing and Testing: Offers specialized typing and testing services critical for the organ transplant market.
  • Laboratory Refrigerators, Freezers, and Storage Tanks: Provides equipment such as ultralow-temperature freezers, refrigerators, and cryopreservation storage tanks for laboratory samples.
  • General Laboratory Equipment: Includes products for temperature control, sample preparation and preservation, centrifugation, and biological safety cabinets.
  • Laboratory Plastics and Chemicals: Supplies essential consumables like various laboratory plastics products and chemicals.
  • Pharma Services: Offers a range of services supporting pharmaceutical research, development, and manufacturing.

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Major Customers of Thermo Fisher Scientific (TMO)

Thermo Fisher Scientific primarily sells its life sciences solutions, analytical instruments, specialty diagnostics, and laboratory products and services to other companies and institutions rather than directly to individuals. Its major customer categories include:

  • Pharmaceutical and Biotechnology Companies: These customers utilize Thermo Fisher's offerings for biological and medical research, drug discovery, and the production of drugs and vaccines.
  • Academic and Government Research Institutions: Universities, government laboratories, and other research bodies use the company's instruments, reagents, and laboratory products for scientific research across various fields. This category also encompasses other research and industrial markets.
  • Clinical Laboratories and Healthcare Providers: This category includes hospitals, diagnostic centers, and clinical laboratories that rely on Thermo Fisher for specialty diagnostics (e.g., immunodiagnostic tests) as well as laboratory equipment and consumables for patient care and disease diagnosis.

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Marc N. Casper Chairman and Chief Executive Officer

Marc N. Casper has been the Chief Executive Officer of Thermo Fisher Scientific since October 2009 and was elected Chairman of the Board in February 2020. He also served as President from 2009 until March 2026. Casper joined Thermo Fisher in 2001 as President of the Life Sciences sector of Thermo Electron. He was named Senior Vice President in 2003, and in 2005 he assumed responsibility for all of the company's operating divisions. Following the merger that created Thermo Fisher Scientific in 2006, Casper was appointed Executive Vice President and President of its Analytical Technologies business, becoming Chief Operating Officer in 2008. Before joining Thermo Fisher, he served as President, Chief Executive Officer, and a Director of Kendro Laboratory Products. Prior to that, he was President–Americas at clinical diagnostics provider Dade Behring Inc. Casper began his career as a strategy consultant at Bain & Company and later worked for Bain Capital.

Stephen Williamson Senior Vice President and Chief Financial Officer

Stephen Williamson will retire from Thermo Fisher Scientific at the end of March 2026, after serving as Chief Financial Officer since 2015. He joined the company in 2001 as Vice President, European Financial Operations, overseeing integration activities across Europe. In 2004, he moved to the U.S. and held various finance leadership roles for the company's operating businesses, becoming Vice President of Financial Operations for Thermo Fisher Scientific in 2008. Before joining Thermo Fisher, Williamson held finance positions at Honeywell International (formerly AlliedSignal), including Chief Financial Officer for Asia-Pacific in Singapore, and other roles in corporate development and operational finance. He began his career with Price Waterhouse in transaction support and audit.

Gianluca Pettiti President and Chief Operating Officer

Gianluca Pettiti will be promoted to President and Chief Operating Officer, effective March 1, 2026. He has been an Executive Vice President since 2021. Pettiti joined Thermo Fisher Scientific through the acquisition of Life Technologies in 2014.

Michael Shafer Executive Vice President

Michael Shafer, currently an Executive Vice President and President of Biopharma Services since April 2024, will take on an expanded role and report directly to the Chief Executive Officer, effective March 1, 2026.

Lisa P. Britt Senior Vice President and Chief Human Resources Officer

Lisa P. Britt joined Thermo Fisher Scientific in March 2017 as Senior Vice President and Chief Human Resources Officer, where she is responsible for leading the company's global Human Resources strategy and operations. Prior to Thermo Fisher, she spent six years with Nexeo Solutions, a global distributor of plastics and chemicals, serving as Executive Vice President and Chief Human Resources Officer. Before Nexeo, Britt worked for Covidien, a global healthcare products leader, for 13 years, holding several HR senior leadership roles, including Vice President, Global Human Resources.

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The key risks to Thermo Fisher Scientific's business are primarily driven by macroeconomic factors, regulatory and geopolitical developments, and challenges related to its acquisition strategy.

  1. Macroeconomic Headwinds and Funding Challenges: Thermo Fisher Scientific faces significant risk from a challenging macroeconomic environment, including potential cuts in government research funding and cautious spending in academic and government sectors globally. Economic weakness, particularly in China, has dampened demand and contributed to a cautious outlook for the company's growth. Inflationary pressures and fluctuating interest rates can also impact operational costs and profit margins, as well as affect funding for the broader biotech industry, which is a key customer segment for Thermo Fisher. This environment has led to a pullback in global biopharmaceutical spending and cost-cutting measures by the company.

  2. Regulatory Changes and Geopolitical Risks: The company operates in highly regulated industries and is exposed to the risk of adverse regulatory changes, such as U.S. drug price negotiation provisions, which could increase expenses or delay product development. Geopolitical factors, including tariffs and evolving policy changes in key markets like China and the U.S., create uncertainty and can directly impact Thermo Fisher's earnings and financial projections. Furthermore, expanding into emerging markets presents additional risks due to political and financial instability.

  3. Acquisition Integration and Financial Risks: Thermo Fisher Scientific frequently engages in strategic acquisitions to expand its market position and capabilities. However, these acquisitions come with inherent risks, including challenges in successfully integrating acquired businesses and technologies, which can lead to operational difficulties. There are also financial risks associated with these transactions, such as concerns over immediate negative impacts on earnings, increased long-term debt and leverage, and the challenge of generating anticipated returns, especially in a less favorable interest-rate environment.

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Thermo Fisher Scientific (TMO) operates within several significant addressable markets globally and in the U.S. Here are the estimated market sizes for its main product and service segments:

  • Life Sciences Solutions: This segment offers reagents, instruments, and consumables for biological and medical research, drug and vaccine production, and disease diagnosis. The global life science tools market, which encompasses these offerings, was valued at approximately USD 151.62 billion in 2025 and is projected to reach around USD 500.09 billion by 2035. For North America, specifically the U.S., the life science tools market size reached USD 60.00 billion in 2025 and is anticipated to grow to approximately USD 154.33 billion by 2035.
  • Analytical Instruments: Thermo Fisher Scientific's Analytical Instruments segment provides various instruments, consumables, software, and services for laboratory, production line, and field use. The global analytical instrumentation market was valued at USD 58.96 billion in 2025 and is projected to increase to USD 98.68 billion by 2034. North America held approximately 34% of the global analytical instrumentation market share in 2025, with the U.S. market reaching USD 14.6 billion in 2025.
  • Specialty Diagnostics: This segment includes immunodiagnostic reagent kits, allergy and asthma tests, autoimmunity tests, culture media, and human leukocyte antigen typing. The global diagnostic tests market, which includes these specialized tests, was valued at USD 286.36 billion in 2024 and is expected to reach USD 545.94 billion by 2032. The U.S. diagnostic tests market alone accounted for 79% of the North American market in 2024.
  • Laboratory Products and Services: This segment offers a broad range of laboratory equipment such as refrigerators, freezers, and biological safety cabinets, along with laboratory plastics, chemicals, and pharma services. The global laboratory supplies market was valued at USD 48.95 billion in 2025 and is projected to reach USD 103.79 billion by 2034. North America led the global laboratory supplies market with a 38% share in 2024. Additionally, the global laboratory equipment service market was valued at USD 20.51 billion in 2025 and is projected to grow to USD 64.91 billion by 2034.

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Here are the expected drivers of future revenue growth for Thermo Fisher Scientific (TMO) over the next 2-3 years:
  1. Growth in Pharmaceutical and Biotechnology End Markets: Thermo Fisher Scientific anticipates continued strong performance within the pharmaceutical and biotechnology sectors, which collectively represent approximately 60% of its revenue. This segment delivered high single-digit growth in the fourth quarter of 2025 and mid-single-digit growth for the full year 2025. Positive customer sentiment, particularly in biotech, is expected to translate into increased spending and budgets, supporting sustained growth in these critical markets.
  2. Strategic Acquisitions: The company actively pursues strategic acquisitions to expand its offerings and market presence. A significant driver for future revenue is the definitive agreement to acquire Clario, a digital endpoint data provider, which generated approximately $1.5 billion in revenue in 2025. Additionally, the acquisition of Olink, a high-growth business, is projected to close in the second quarter of 2026 and is expected to enhance Thermo Fisher's endpoint solution capabilities.
  3. New Product Launches and Innovation: Investment in research and development (R&D) and the successful launch of innovative products are key to revenue growth. Recent examples of high-impact product launches include the Orbitrap Astro Zoom mass spectrometer and the DynaDrive bioreactor. Thermo Fisher is also leveraging advanced technologies through a new collaboration with OpenAI to promote scientific innovation and a strategic partnership with NVIDIA to advance scientific instrumentation and accelerate laboratory performance.
  4. Expansion of Service Capabilities and Integrated Solutions: Thermo Fisher is enhancing its comprehensive service capabilities, including integrated clinical research and manufacturing, to accelerate drug development for its customers. The company's bioproduction business has demonstrated excellent growth, and its "Accelerator program" has shown strong customer adoption, contributing to increased revenue from its service offerings.
  5. Reshoring and Increased U.S. Manufacturing Capacity: Significant commitments to reshoring manufacturing operations within the United States, including a $2 billion investment in capacity, are expected to drive above-trend growth from 2027 to 2029. This strategic initiative aims to increase Thermo Fisher's market share in new U.S. facilities and bolster domestic medicine production capabilities.

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Share Repurchases

  • Thermo Fisher Scientific authorized a $5 billion share repurchase program in November 2025.
  • The company executed annual share repurchases of $4 billion in 2024 and $3 billion in 2023.

Share Issuance

  • The number of Thermo Fisher Scientific's shares outstanding has shown a declining trend, with a 1.31% decrease in 2025 from 2024, indicating net share repurchases rather than significant share issuance.

Outbound Investments

  • In November 2025, Thermo Fisher acquired Clario for $9 billion, enhancing its clinical trial supply services.
  • The company completed the acquisition of Solventum's Purification & Filtration business for approximately $4.0-$4.1 billion in September 2025, strengthening its bioproduction offerings and expanding into industrial filtration.
  • Other significant acquisitions include Olink for $3.1 billion in 2024 (announced 2023) and PPD for $17.4 billion in 2021, a contract research organization.

Capital Expenditures

  • Thermo Fisher Scientific's capital expenditures increased in each of the last five fiscal years, from $259.1 million in 2021 to $2.2128 billion in 2025.
  • The average annual capital expenditures from 2021 to 2025 were $1.1013 billion.
  • These expenditures are primarily focused on maintaining existing assets and expanding to new property, plant, and equipment.

Better Bets vs. Thermo Fisher Scientific (TMO)

Latest Trefis Analyses

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

TMODHRAILMNBDXWATMedian
NameThermo F.Danaher Agilent .Illumina Becton D.Waters  
Mkt Price580.02199.98141.34193.72177.07399.70196.85
Mkt Cap215.2141.039.929.348.732.844.3
Rev LTM46,33625,1077,2324,49323,2503,77115,241
Op Inc LTM8,4765,1271,5558923,3446042,450
FCF LTM7,3185,4661,0879312,5092641,798
FCF 3Y Avg7,1505,1361,2717732,7684662,020
CFO LTM9,0136,6351,4521,0953,2623902,357
CFO 3Y Avg8,6466,4171,6449233,4876062,566

Growth & Margins

TMODHRAILMNBDXWATMedian
NameThermo F.Danaher Agilent .Illumina Becton D.Waters  
Rev Chg LTM7.2%4.6%9.1%4.9%17.4%26.4%8.2%
Rev Chg 3Y Avg2.2%2.9%1.1%0.3%7.1%9.0%2.5%
Rev Chg Q10.5%5.5%10.0%9.4%5.4%91.4%9.7%
QoQ Delta Rev Chg LTM2.5%1.3%2.4%2.3%1.1%19.1%2.3%
Op Inc Chg LTM7.8%16.1%9.7%8.3%26.1%-28.6%9.0%
Op Inc Chg 3Y Avg6.1%-3.3%-1.4%675.4%10.7%-9.6%2.4%
Op Mgn LTM18.3%20.4%21.5%19.9%14.4%16.0%19.1%
Op Mgn 3Y Avg18.0%20.0%20.8%13.4%13.5%23.8%19.0%
QoQ Delta Op Mgn LTM0.1%1.2%0.9%0.3%-0.5%-9.3%0.2%
CFO/Rev LTM19.5%26.4%20.1%24.4%14.0%10.3%19.8%
CFO/Rev 3Y Avg19.7%26.5%24.3%21.0%16.8%19.6%20.4%
FCF/Rev LTM15.8%21.8%15.0%20.7%10.8%7.0%15.4%
FCF/Rev 3Y Avg16.3%21.2%18.8%17.6%13.3%15.1%17.0%

Valuation

TMODHRAILMNBDXWATMedian
NameThermo F.Danaher Agilent .Illumina Becton D.Waters  
Mkt Cap215.2141.039.929.348.732.844.3
P/S4.65.65.56.52.18.75.6
P/Op Inc25.427.525.632.814.654.426.6
P/EBIT23.627.923.726.319.152.325.0
P/E30.935.228.235.551.773.135.3
P/CFO23.921.327.526.714.984.325.3
Total Yield3.5%3.5%4.3%2.8%4.3%1.4%3.5%
Dividend Yield0.3%0.7%0.7%0.0%2.4%0.0%0.5%
FCF Yield 3Y Avg3.9%3.4%3.5%4.2%5.3%2.3%3.7%
D/E0.20.20.10.10.30.20.2
Net D/E0.20.20.00.00.30.20.2

Returns

TMODHRAILMNBDXWATMedian
NameThermo F.Danaher Agilent .Illumina Becton D.Waters  
1M Rtn12.3%3.0%7.8%1.0%13.3%6.6%7.2%
3M Rtn22.4%14.1%19.4%39.7%16.4%14.0%17.9%
6M Rtn7.2%-6.9%9.5%45.0%10.6%6.1%8.3%
12M Rtn29.7%3.2%25.8%105.1%33.9%43.9%31.8%
3Y Rtn6.1%-10.4%14.3%6.5%-13.2%38.0%6.3%
1M Excs Rtn10.7%1.8%6.5%0.1%14.6%5.5%6.0%
3M Excs Rtn18.1%9.9%15.6%31.2%18.5%9.7%16.9%
6M Excs Rtn-9.2%-20.5%-5.3%32.3%-2.2%-8.0%-6.7%
12M Excs Rtn2.4%-21.2%1.6%75.8%8.1%19.7%5.2%
3Y Excs Rtn-61.2%-78.7%-50.4%-63.2%-82.7%-22.8%-62.2%

Comparison Analyses

Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
Laboratory Products and Biopharma Services23,98423,15723,04122,51114,862
Life Sciences Solutions10,3749,6319,97713,53215,631
Analytical Instruments7,5547,4637,2636,6246,069
Specialty Diagnostics4,6764,5124,4054,7635,659
Elimination of intersegment revenues-2,033-1,885-1,829-2,515-3,010
Total44,55542,87842,85744,91539,211


Operating Income by Segment
$ Mil20252024202320222021
Life Sciences Solutions3,7683,5033,4205,5827,817
Laboratory Products and Biopharma Services3,3503,0903,3582,8721,844
Analytical Instruments1,7361,9551,9081,5071,197
Specialty Diagnostics1,2561,1591,1241,0241,280
Cost of revenues adjustments-64-47-95-46-8
Selling, general and administrative expenses adjustments-2078-59-37-144
Restructuring and other costs-362-379-459-114-197
Amortization of acquisition-related intangible assets-1,730-1,952-2,338-2,395-1,761
Total7,7477,3376,8598,39310,028


Assets by Segment
$ Mil20252024202320222021
Unallocated amounts95,91984,03185,31483,340 
Laboratory Products and Biopharma Services6,4856,1456,3506,42852,639
Life Sciences Solutions3,4462,9823,1863,84522,751
Analytical Instruments3,1702,9442,7262,4659,692
Specialty Diagnostics1,3231,2181,1501,0766,010
Corporate/Other    4,031
Total110,34397,32098,72697,15495,123


Price Behavior

Price Behavior
Market Price$580.02 
Market Cap ($ Bil)215.2 
First Trading Date09/01/1987 
Distance from 52W High-9.1% 
   50 Days200 Days
DMA Price$514.67$530.76
DMA Trendupup
Distance from DMA12.7%9.3%
 3M1YR
Volatility35.0%30.5%
Downside Capture-107.5848.65
Upside Capture1.7366.95
Correlation (SPY)-3.5%26.2%
TMO Betas & Captures as of 7/31/2026

 1M2M3M6M1Y3Y
Beta-0.64-0.050.040.630.670.78
Up Beta0.04-0.310.070.860.790.87
Down Beta-1.451.181.171.080.720.85
Up Capture49%10%9%30%56%30%
Bmk +ve Days11223567138427
Stock +ve Days13223363124371
Down Capture-175%-101%-101%54%64%90%
Bmk -ve Days11212859114326
Stock -ve Days9213063128382

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with TMO
TMO24.9%30.7%0.74-
Sector ETF (XLV)25.8%15.6%1.2754.2%
Equity (SPY)23.5%12.9%1.3726.0%
Gold (GLD)25.3%28.3%0.798.9%
Commodities (DBC)32.4%19.8%1.30-13.1%
Real Estate (VNQ)12.9%13.8%0.6426.5%
Bitcoin (BTCUSD)-43.6%43.0%-1.2115.2%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with TMO
TMO2.0%27.6%0.07-
Sector ETF (XLV)6.1%15.0%0.2265.7%
Equity (SPY)13.2%17.2%0.5952.6%
Gold (GLD)17.9%18.5%0.788.1%
Commodities (DBC)8.0%19.6%0.313.3%
Real Estate (VNQ)2.3%18.9%0.0247.8%
Bitcoin (BTCUSD)10.0%53.0%0.3820.0%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with TMO
TMO14.2%26.5%0.52-
Sector ETF (XLV)10.0%16.6%0.4868.6%
Equity (SPY)15.3%17.9%0.7357.8%
Gold (GLD)11.8%16.2%0.599.0%
Commodities (DBC)7.4%18.0%0.3310.6%
Real Estate (VNQ)4.9%20.7%0.2043.4%
Bitcoin (BTCUSD)58.3%66.2%0.9814.2%

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Short Interest

Short Interest: As Of Date7152026
Short Interest: Shares Quantity5.3 Mil
Short Interest: % Change Since 6302026-1.0%
Average Daily Volume1.8 Mil
Days-to-Cover Short Interest3.0 days
Basic Shares Quantity371.0 Mil
Short % of Basic Shares1.4%

Earnings Returns History

Updated 8/3/2026
Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
7/23/20268.7%9.5% 
4/23/2026-9.2%-9.3%-12.6%
1/29/2026-2.6%-7.0%-14.3%
10/22/20251.7%-0.1%2.8%
7/23/20259.1%12.8%15.7%
4/23/2025-0.7%-1.7%-8.4%
1/30/20256.8%2.5%-6.9%
10/23/2024-1.7%-6.6%-12.5%
...
SUMMARY STATS   
# Positive141111
# Negative101312
Median Positive2.2%4.6%3.8%
Median Negative-2.7%-2.9%-6.9%
Max Positive9.1%12.8%15.7%
Max Negative-9.2%-9.3%-14.3%
Collapse to Preview
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
7/23/20268.7%9.5% 
4/23/2026-9.2%-9.3%-12.6%
1/29/2026-2.6%-7.0%-14.3%
10/22/20251.7%-0.1%2.8%
7/23/20259.1%12.8%15.7%
4/23/2025-0.7%-1.7%-8.4%
1/30/20256.8%2.5%-6.9%
10/23/2024-1.7%-6.6%-12.5%
7/24/20244.1%11.4%10.5%
4/24/20240.5%-1.0%2.8%
1/31/2024-5.0%-1.2%0.5%
10/25/2023-5.5%-2.9%6.4%
7/26/20230.6%-4.4%-4.5%
4/26/2023-2.8%-0.8%-6.9%
2/1/20233.0%2.2%-3.8%
10/26/2022-2.3%0.6%6.3%
7/28/20222.7%1.0%0.6%
4/28/20227.4%8.2%3.8%
2/2/20221.7%-1.1%-6.7%
10/27/20210.6%4.6%4.1%
7/28/2021-0.4%1.3%3.4%
4/29/2021-4.4%-3.7%-2.7%
2/1/20211.1%-3.4%-9.3%
10/21/20200.8%5.2%-2.4%
SUMMARY STATS   
# Positive141111
# Negative101312
Median Positive2.2%4.6%3.8%
Median Negative-2.7%-2.9%-6.9%
Max Positive9.1%12.8%15.7%
Max Negative-9.2%-9.3%-14.3%

SEC Filings

Expand for More
Report DateFiling DateFiling
06/30/202607/31/202610-Q
03/31/202605/01/202610-Q
12/31/202502/26/202610-K
09/30/202510/31/202510-Q
06/30/202508/01/202510-Q
03/31/202505/02/202510-Q
12/31/202402/20/202510-K
09/30/202411/01/202410-Q
06/30/202408/02/202410-Q
03/31/202405/03/202410-Q
12/31/202302/22/202410-K
09/30/202311/03/202310-Q
06/30/202308/04/202310-Q
03/31/202305/05/202310-Q
12/31/202202/23/202310-K
09/30/202211/04/202210-Q
Collapse to Preview
Report DateFiling DateFiling
06/30/202607/31/202610-Q
03/31/202605/01/202610-Q
12/31/202502/26/202610-K
09/30/202510/31/202510-Q
06/30/202508/01/202510-Q
03/31/202505/02/202510-Q
12/31/202402/20/202510-K
09/30/202411/01/202410-Q
06/30/202408/02/202410-Q
03/31/202405/03/202410-Q
12/31/202302/22/202410-K
09/30/202311/03/202310-Q
06/30/202308/04/202310-Q
03/31/202305/05/202310-Q
12/31/202202/23/202310-K
09/30/202211/04/202210-Q
06/30/202208/05/202210-Q
03/31/202205/06/202210-Q
12/31/202102/24/202210-K
09/30/202111/04/202110-Q
06/30/202108/06/202110-Q
03/31/202105/07/202110-Q
12/31/202002/25/202110-K
09/30/202010/30/202010-Q
06/30/202007/31/202010-Q
03/31/202005/01/202010-Q
12/31/201902/26/202010-K
09/30/201911/01/201910-Q

Insider Activity

Updated 7/28/2026
Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Pettiti, GianlucaPresident & COODirectSell7282026565.00400226,00013,927,720Form
2Pettiti, GianlucaPresident & COODirectSell4292026462.66400185,06411,590,018Form
3Shafer, Michael DExecutive Vice PresidentDirectSell3122026499.401,607802,53610,462,407Form
4Casper, Marc NChairman & CEODirectSell3092026514.824,0002,059,26163,798,677Form
5Casper, Marc NChairman & CEODirectSell3052026512.405,0002,561,99463,499,201Form
Collapse to Preview
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Pettiti, GianlucaPresident & COODirectSell7282026565.00400226,00013,927,720Form
2Pettiti, GianlucaPresident & COODirectSell4292026462.66400185,06411,590,018Form
3Shafer, Michael DExecutive Vice PresidentDirectSell3122026499.401,607802,53610,462,407Form
4Casper, Marc NChairman & CEODirectSell3092026514.824,0002,059,26163,798,677Form
5Casper, Marc NChairman & CEODirectSell3052026512.405,0002,561,99463,499,201Form
6Casper, Marc NChairman & CEODirectSell3052026503.105,0002,515,49562,346,718Form
7Pettiti, GianlucaExecutive Vice PresidentDirectSell2112026541.20400216,48011,231,103Form
8Lagarde, MichelExecutive Vice President & COODirectSell12052025563.5622,04612,424,24447,404,925Form
9Lagarde, MichelExecutive Vice President & COODirectSell12042025583.3932,00018,668,52638,200,419Form
10Lagarde, MichelExecutive Vice President & COODirectSell12042025581.9230,00017,457,60017,154,949Form
11Lowery, Frederick MExecutive Vice PresidentDirectSell12032025581.946,9124,022,3698,360,949Form
12Lowery, Frederick MExecutive Vice PresidentDirectSell12032025597.686,9134,131,7628,587,091Form
13Shafer, Michael DExecutive Vice PresidentDirectSell11262025600.0010,7256,435,00011,238,482Form
14Lagarde, MichelExecutive Vice President & COODirectSell11142025594.424,6382,756,92013,956,928Form
15Britt, Lisa PSr. VP and Chief HR OfficerDirectSell11142025588.261,058622,1367,698,758Form
16Pettiti, GianlucaExecutive Vice PresidentDirectSell11122025580.002,9751,725,50012,268,289Form
17Britt, Lisa PSr. VP and Chief HR OfficerDirectSell11102025571.6210,2255,844,8508,085,502Form
18Casper, Marc NChairman & CEODirectSell10282025566.107,2504,104,24264,401,093Form
19Pettiti, GianlucaExecutive Vice PresidentDirectSell10282025574.15400229,66012,144,549Form
20Casper, Marc NChairman & CEODirectSell10282025573.5417,1049,809,86265,247,446Form
21Casper, Marc NChairman & CEODirectSell9092025500.50400200,20156,938,308Form
22Holmes, Joseph RVP & Chief Accounting OfficerDirectSell9022025492.63385189,6621,142,396Form
23Casper, Marc NChairman & CEODirectSell8262025500.9610,0005,009,58657,697,217Form
24Casper, Marc NChairman & CEODirectSell8212025500.04295147,51257,591,633Form
25Casper, Marc NChairman & CEODirectSell8212025500.17201100,53457,606,057Form
26Casper, Marc NChairman & CEODirectSell8072025454.458,0003,635,56752,340,183Form
27Casper, Marc NChairman & CEODirectSell8072025451.8210,0004,518,21652,037,931Form
28Pettiti, GianlucaExecutive Vice PresidentDirectSell7282025479.98400191,99210,735,677Form

Investor Activity (13F)

Updated Aug 7, 2026
13F holdings as of Mar 31, 2026 (Q1 2026)

Active managers (13F portfolio over $250M, at least 3 holdings) with a position over $5M that is either over 10% of their portfolio or held in a concentrated book of 50 or fewer total positions. Index/ETF, sovereign, bank, community-bank and charitable/donor-advised filers are excluded.

Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Arvin Capital Management LP$54.9 Mil12.8%23ADD +64.7%13F
Spinecap SAS$34.2 Mil12.5%15Hold13F
Cryder Capital Partners LLP$185.2 Mil12.1%10Hold13F
C Partners Holding GmbH$32.1 Mil10.1%7ADD +20.2%13F
Lindsell Train Ltd$303.4 Mil9.7%27TRIM -10.5%13F
Tri Locum Partners LP$65.1 Mil9.1%17New13F
Unisphere Establishment$1.0 Bil8.5%50ADD +5.1%13F
EdgePoint Investment Group Inc.$943.2 Mil7.6%37ADD +38.5%13F
Caledonia Investments PLC$55.0 Mil6.4%15Hold13F
Route One Investment Company, L.P.$127.2 Mil5.6%18Hold13F
Wilson Asset Management (International) PTY LTD$18.7 Mil5.3%43ADD +14.3%13F
DKRT Investments Corp.$20.6 Mil5.2%48New13F
Rempart Asset Management Inc.$23.3 Mil4.9%36TRIM -8.7%13F
America First Investment Advisors, LLC$26.0 Mil4.8%41Hold13F
Atle Fund Management AB$14.4 Mil4.7%39TRIM -23.2%13F
Longview Partners (Guernsey) LTD$325.8 Mil4.6%25TRIM -22.0%13F
Weitz Investment Management, Inc.$59.5 Mil4.2%49TRIM -10.3%13F
Bristol Gate Capital Partners Inc.$63.4 Mil4.1%31TRIM -6.5%13F
Jia Investment Alliance PTE. LTD.$38.7 Mil4.1%24Hold13F
Southpoint Capital Advisors LP$196.6 Mil4.0%41ADD +300.0%13F
Dundas Partners LLP$47.9 Mil3.8%49Hold13F
Local Pensions Partnership Investment Ltd$168.1 Mil3.6%32TRIM -5.1%13F
Eldred Rock Partners, LLC$14.0 Mil3.6%31New13F
Mirova US LLC$302.3 Mil3.4%42Hold13F
Generation Investment Management LLP$380.2 Mil3.4%29TRIM -30.4%13F
Active ManagerValue% of PortfolioTotal PositionsQoQFiling
D1 Capital Partners L.P.$356.4 Mil3.2%44New13F
Tri Locum Partners LP$65.1 Mil9.1%17New13F
Spear Holdings RSC Ltd$29.8 Mil3.2%17New13F
PBCay One RSC Ltd$29.8 Mil3.2%17New13F
MKP Capital Management, L.L.C.$29.5 Mil1.0%19New13F
DKRT Investments Corp.$20.6 Mil5.2%48New13F
Petrus Trust Company, LTA$17.2 Mil1.9%27New13F
Eldred Rock Partners, LLC$14.0 Mil3.6%31New13F
Cincinnati Specialty Underwriters Insurance CO$7.8 Mil1.9%46New13F
Southpoint Capital Advisors LP$196.6 Mil4.0%41ADD +300.0%13F
Retail Employees Superannuation Pty Ltd as trustee for Retail Employees Superannuation Trust$21.9 Mil3.3%28ADD +149.0%13F
Arvin Capital Management LP$54.9 Mil12.8%23ADD +64.7%13F
Nuance Investments, LLC$14.9 Mil2.1%43ADD +44.3%13F
EdgePoint Investment Group Inc.$943.2 Mil7.6%37ADD +38.5%13F
C Partners Holding GmbH$32.1 Mil10.1%7ADD +20.2%13F
Wilson Asset Management (International) PTY LTD$18.7 Mil5.3%43ADD +14.3%13F
Glenview Capital Management, LLC$123.1 Mil3.3%41ADD +11.9%13F
Skye Global Management LP$58.2 Mil1.3%44ADD +9.7%13F
Unisphere Establishment$1.0 Bil8.5%50ADD +5.1%13F
Active ManagerValue% of PortfolioTotal PositionsQoQAs OfFiling
BlueSpruce Investments, LP$230.6 Mil5.9%9ExitedDec 31, 202513F
Third Point LLC$29.0 Mil0.4%44ExitedDec 31, 202513F
Sector Gamma AS$12.6 Mil2.9%36ExitedDec 31, 202513F
J. Stern & Co. LLP$27.0 Mil2.6%49TRIM -99.8%Mar 31, 202613F
Generation Investment Management LLP$380.2 Mil3.4%29TRIM -30.4%Mar 31, 202613F
Atle Fund Management AB$14.4 Mil4.7%39TRIM -23.2%Mar 31, 202613F
Longview Partners (Guernsey) LTD$325.8 Mil4.6%25TRIM -22.0%Mar 31, 202613F
Lindsell Train Ltd$303.4 Mil9.7%27TRIM -10.5%Mar 31, 202613F
Weitz Investment Management, Inc.$59.5 Mil4.2%49TRIM -10.3%Mar 31, 202613F
Rempart Asset Management Inc.$23.3 Mil4.9%36TRIM -8.7%Mar 31, 202613F
Haverford Financial Services, Inc.$5.2 Mil1.5%46TRIM -7.9%Mar 31, 202613F
Bristol Gate Capital Partners Inc.$63.4 Mil4.1%31TRIM -6.5%Mar 31, 202613F
Local Pensions Partnership Investment Ltd$168.1 Mil3.6%32TRIM -5.1%Mar 31, 202613F
Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Unisphere Establishment$1.0 Bil8.5%50ADD +5.1%13F
EdgePoint Investment Group Inc.$943.2 Mil7.6%37ADD +38.5%13F
Generation Investment Management LLP$380.2 Mil3.4%29TRIM -30.4%13F
D1 Capital Partners L.P.$356.4 Mil3.2%44New13F
Longview Partners (Guernsey) LTD$325.8 Mil4.6%25TRIM -22.0%13F
Lindsell Train Ltd$303.4 Mil9.7%27TRIM -10.5%13F
Mirova US LLC$302.3 Mil3.4%42Hold13F
Southpoint Capital Advisors LP$196.6 Mil4.0%41ADD +300.0%13F
Cryder Capital Partners LLP$185.2 Mil12.1%10Hold13F
Local Pensions Partnership Investment Ltd$168.1 Mil3.6%32TRIM -5.1%13F
Route One Investment Company, L.P.$127.2 Mil5.6%18Hold13F
Glenview Capital Management, LLC$123.1 Mil3.3%41ADD +11.9%13F
Tri Locum Partners LP$65.1 Mil9.1%17New13F
Bristol Gate Capital Partners Inc.$63.4 Mil4.1%31TRIM -6.5%13F
Weitz Investment Management, Inc.$59.5 Mil4.2%49TRIM -10.3%13F
Skye Global Management LP$58.2 Mil1.3%44ADD +9.7%13F
Caledonia Investments PLC$55.0 Mil6.4%15Hold13F
Arvin Capital Management LP$54.9 Mil12.8%23ADD +64.7%13F
Dundas Partners LLP$47.9 Mil3.8%49Hold13F
Jia Investment Alliance PTE. LTD.$38.7 Mil4.1%24Hold13F
Spinecap SAS$34.2 Mil12.5%15Hold13F
C Partners Holding GmbH$32.1 Mil10.1%7ADD +20.2%13F
Spear Holdings RSC Ltd$29.8 Mil3.2%17New13F
PBCay One RSC Ltd$29.8 Mil3.2%17New13F
MKP Capital Management, L.L.C.$29.5 Mil1.0%19New13F

TMO Trade Sentinel


Stock Conviction

High Conviction

CONVICTION RATIONALE

Thermo Fisher is demonstrating a clear re-acceleration in its core business, with organic growth jumping to 5% in the latest quarter. Management's confidence is high, reflected in a raised full-year outlook for both revenue and earnings. This operational momentum, combined with disciplined M&A, supports a durable growth profile.

STOCK ARCHETYPE
Diversified Tools & Services

(Volume of products sold) x (Average Selling Price) + (Volume of services delivered) x (Service fees) Productivity improvements via the company's PPI Business System, business mix, and operating leverage from volume growth.

Looking for high-conviction positions with a better risk/reward profile? See what's currently in the Trefis High Quality Portfolio.
INVESTMENT THESIS
Is the post-pandemic growth re-acceleration durable and profitable?

Evidence points to a sustained recovery, driven by strengthening pharma and biotech spending and elite operational execution.

Mechanism: Accelerating organic growth (5% in Q2) and disciplined M&A drive revenue upside, while operating leverage expands margins. Management raised 2026 EPS guidance to a range of $24.93 to $25.33, representing 9% to 11% growth.
Supporting Evidence:
  • Organic revenue growth accelerated to 5% in Q2 2026 from 1% in Q1.
  • Full-year 2026 adjusted EPS guidance was raised to $24.93-$25.33.
  • Inventory grew 1.2% while revenue grew 10.5%, signaling strong end-market demand.
  • Management expects organic growth to step up to 4% in H2 2026.
PRIMARY RISK
Dependence on Cyclical Customer Spending

A broad-based slowdown in pharma, biotech, or government R&D budgets could halt the current growth recovery. Demand for some products depends on customer capital spending policies, which can be volatile.

Mechanism: A miss on quarterly organic growth targets would confirm a slowdown is underway.
Supporting Evidence:
  • Demand depends on customer capital spending and government funding policies.
  • A US federal government shutdown occurred in October 2025.
  • The stock reacted -9.0% to a prior quarter's results in April 2026.
  • Net debt increased to $38.5 billion from $28.8 billion year-over-year.
Key KPI Watchlist
KPI Status Rationale
Organic Revenue Growth5% organic growth in Q2 2026 - AcceleratingThe sharp acceleration in the second quarter reflects strengthening customer activity across all end markets. The prior quarter's softer 1% growth was partly attributed to having one less selling day. Management commentary indicates the Q2 strength was broad-based and represented a clear pickup in customer spending.
Pharma and Biotech End Market GrowthMid-single-digit growth in Q2 2026 - StableGrowth in the company's largest end market decelerated from a strong Q4 2025 but has since stabilized at a healthy mid-single-digit rate for two consecutive quarters. Management noted that after a period of increased activity, biotech spending is now translating into revenue, suggesting improving underlying momentum.
Adjusted Operating Margin22.8% (Q2 2026)Indicates the profitability of core business operations, excluding certain non-recurring or non-cash items. Expansion of this margin is a key focus for management.
Inventory-vs-Revenue Growth Divergence-9.3 percentage points (Q2 2026)A negative divergence, where inventory grows significantly slower than revenue, indicates strong demand and efficient inventory management. The latest quarter's divergence improved from -1.0 percentage points in the prior quarter.
Core Investment Debate

Pharma/Biotech Recovery vs. Margin Mix-Shift

BULL VIEW

Strengthening pharma and biotech spending, which drove Q2's 5% organic growth, will continue to accelerate, providing enough volume leverage to offset any negative mix effects and drive strong earnings growth.

CORE TENSION

Can accelerating organic growth (5% in Q2) overcome the margin drag from the fast-growing services segment?


PREVAILING SENTIMENT
BULLISH

The latest evidence favors the bulls. Management raised full-year EPS guidance and delivered a 22.8% adjusted operating margin, indicating confidence in managing profitability despite the mix.

BEAR VIEW

The fastest-growing Laboratory Products and Biopharma Services segment has lower margins. This mix shift will cap overall profitability, even if top-line growth meets expectations, disappointing investors.

Next 6 months: Risks and Catalysts
Timeline Event & Metric To Watch
8/6/2026
Peer Earnings Read-Through
Watch: BDX's commentary on pharma and biotech customer spending, and any signs of market slowdown.
10/19/2026
Peer DHR Earnings
Watch: Peer Danaher (DHR) is scheduled to report earnings.
10/20/2026
Heightened Earnings Expectations
Watch: Any miss on revenue or EPS versus guidance, or a cautious outlook for Q4.
10/20/2026
Clario Integration Progress
Watch: Updates on integration costs, revenue synergies, and performance of the acquired clinical research business in the Q3 report.
10/28/2026
Peer ILMN Earnings
Watch: Peer Illumina (ILMN) is scheduled to report earnings.
Key Events in Last 6 Months
Date Event Stock Impact
2026-07-23
Second Quarter Results Reported
Details: Q2 revenue grew 10% to $11.99 billion and adjusted EPS grew 13% to $6.03. The company raised its full-year 2026 guidance.
+7.9%
$526.46 -> $568.26
2026-06-01
Orbitrap Platform Expanded
Details: The company expanded its suite of Thermo Scientific Orbitrap mass spectrometry platforms at the ASMS Conference.
-2.1%
$492.02 -> $481.60
2026-05-20
Investor Day Hosted
Details: The company hosted its Investor Day, where senior leadership highlighted the company's industry leadership and growth outlook.
+0.3%
$447.36 -> $448.92
2026-04-23
First Quarter Results Reported
Details: First quarter revenue grew 6% to $11.01 billion. The stock had a -9.0% two-day reaction to the report.
-8.6%
$513.47 -> $469.24
2026-03-24
Clario Acquisition Completed
Details: The company completed its acquisition of Clario Holdings, Inc., a provider of endpoint data solutions for clinical trials, for $8.875 billion in cash.
+2.6%
$477.64 -> $490.28
2026-02-25
Quarterly Dividend Increased
Details: The Board of Directors authorized a quarterly cash dividend, a 10% increase over the previous dividend.
+0.9%
$514.58 -> $519.09
Risk Management
Position Sizing

4% - 6%

NORMAL POSITION

Sizing is volatility-based: TMO trades at roughly 30% annualized options-implied volatility versus about 14% for the S&P 500 (2.1x the market), around the 59th percentile of its own trailing year. A 4% - 6% position keeps a single-name swing of that size within a diversified portfolio's risk budget.

Diversification Alternatives
DHR - Danaher
Higher-Margin Compounder

Danaher offers a higher-margin profile, with a trailing-twelve-month gross margin of 58.5% compared to Thermo Fisher's 40.8%, reflecting a different business mix.

Core Thesis: A high-quality compounder also seeing a recovery in its end markets, with core revenue growth of 4.5%.
A - a business partner
Focused Instrument Play

Agilent provides more focused exposure to the analytical instruments market and also has a higher operating margin at 21.5% versus Thermo Fisher's 18.3%.

Core Thesis: A direct competitor in analytical instruments that is also performing well, reporting 6.3% core revenue growth in its latest quarter.
How Is The Market Pricing TMO?

A diversified 'picks and shovels' provider for the entire life sciences and healthcare R&D ecosystem, benefiting from broad-based scientific advancement.

Thermo Fisher is the world leader in serving science, capitalizing on its scale and trusted partner status with customers. Its growth strategy is based on high-impact innovation, a comprehensive commercial engine, and disciplined capital deployment, including strategic M&A. The company is currently seeing strengthening customer activity across its end markets, particularly in pharma and biotech, leading to accelerating growth.

What will confirm the thesis

Sustained or accelerating growth in pharma and biotech R&D spending, successful integration of recent acquisitions like Clario, and continued margin expansion through its PPI business system.

What will damage the thesis

A significant downturn in customer capital spending, particularly from government or academic institutions, or failure to integrate acquisitions and realize synergies.

Noise: Real but irrelevant to thesis

Minor quarterly fluctuations in smaller business lines or geographies; typical seasonality which historically sees stronger revenue in the fourth quarter.

Repricing Catalyst

The company's recent Q2 earnings beat, raised full-year guidance, and management commentary indicating that customer activity across end markets continues to strengthen.

What TMO Makes & Who Pays
TTM figures based on the twelve months through fiscal Q1 2026
Life Sciences Solutions
$10.7B TTM (24% of Total) · 61% Margin
What It Is

Provides reagents, instruments, and consumables used in biological and medical research, discovery and production of new drugs and vaccines, and disease diagnosis. Customers are in pharmaceutical, biotechnology, agricultural, clinical, healthcare, academic, and government markets.

Who Pays & How

Pharmaceutical, biotech, and research institutions pay for solutions that enable the discovery and production of new drugs and vaccines, and the diagnosis of disease. The segment's products are critical for molecular biology, protein biology, and genomic research.

Sales of products and consumables.
Competition
Peers include Danaher (DHR) and Illumina (ILMN).
Peers like Illumina have higher gross margins (66.2%) and a more focused R&D spend (21.7% of revenue).
The company's competitive success depends on technical performance, product differentiation, reputation, customer service, and active research programs.
Analytical Instruments
$7.6B TTM (17% of Total) · 37% Margin
What It Is

Provides instruments, consumables, software, and services for a range of applications in chromatography, mass spectrometry, chemical analysis, and electron microscopy. Customers are in pharmaceutical, biotechnology, academic, government, environmental, industrial, and clinical laboratory markets.

Who Pays & How

Research, industrial, and clinical labs pay for high-end instruments that enable organic and inorganic sample analysis, power R&D, and provide production solutions, particularly in the life sciences, materials sciences, and semiconductor markets.

Sales of instruments, with recurring revenue from associated consumables, software, and services.
Competition
Peers include Danaher (DHR), Agilent Technologies (A), and Waters (WAT).
Peers like Agilent have higher operating margins (21.5% vs. TMO's 18.3% TTM).
Success is driven by technological advances, product reliability, depth of capabilities, and a reputation as a quality provider.
Specialty Diagnostics
$4.7B TTM (10% of Total) · 47% Margin
What It Is

Offers a wide range of diagnostic test kits, reagents, culture media, instruments, and associated products. Customers include healthcare, clinical, pharmaceutical, industrial, and food safety laboratories.

Who Pays & How

Healthcare and clinical labs pay for products that increase the speed and accuracy of diagnoses for conditions like allergies, asthma, autoimmune diseases, and for drugs-of-abuse testing, improving patient care cost-efficiently.

Sales of diagnostic kits, reagents, and instruments.
Competition
Peers include Becton Dickinson (BDX) and Danaher (DHR).
Peers like Danaher have significantly higher gross margins (58.5%).
Competitive factors include product and service differentiation, availability, reliability, and customer support.
Laboratory Products and Biopharma Services
$24.4B TTM (54% of Total) · 23% Margin
What It Is

Offers a comprehensive range of lab consumables, equipment, and chemicals, as well as outsourced services for drug development, clinical research, clinical trials, and commercial drug manufacturing. Customers include pharmaceutical, biotechnology, academic, government, industrial, and clinical laboratory markets.

Who Pays & How

Pharmaceutical and biotech companies pay for outsourced services (pharma services and clinical research) to improve productivity and cost-efficiency in drug development and manufacturing, and for a wide range of lab products through the research and safety market channel.

A mix of product sales and outsourced service contracts.
Competition
Peers in the services space are not explicitly named, but the overall peer set includes large, diversified healthcare companies like Danaher (DHR) and Becton Dickinson (BDX).
This segment has the lowest operating margin of the four, suggesting a more competitive or cost-intensive structure compared to peers with higher overall margins.
The company's moat is its unique combination of self-manufactured and sourced products and an extensive service offering, allowing customers to focus on their core activities.
TMO Evolution: Price Return by Era
2021-2022 · Pre-2023 Growth
+17%
The company saw significant revenue growth, particularly in the Life Sciences Solutions and Specialty Diagnostics segments, which peaked in 2021 and 2022 respectively, likely driven by pandemic-related demand.
2023-2025 · Post-Pandemic Normalization and Services Expansion
+6%
Revenue in Life Sciences Solutions and Specialty Diagnostics moderated from their peaks, while the Laboratory Products and Biopharma Services segment became the largest and fastest-growing part of the business, indicating a strategic focus on expanding outsourced services for the pharma and biotech industries.
Market Appears To Be Cautiously Supportive
Price structure is showing early stress, with SMA alignment beginning to break down. Relative to SPY: Strong 63D outperformance but 'relative strength' momentum is fading, indicating that money rotation may be maturing. Volume and momentum are strongly confirming. The institutional accumulation is evident and momentum is accelerating. Earnings history is strongly validating. The market rewarded the print and institutional follow-through confirms thesis re-rating is underway.
① Structure
-1
Structural pillar score (-4 to +4). Driven by trend regime, SMA cross events, proximity to 52W high, and relative strength vs SPY.
② Volume / Momentum
+4
Volume/Momentum pillar score (-4 to +4). Driven by institutional footprint score, OBV divergence, and momentum character.
③ Catalyst
+3
Catalyst pillar score (-4 to +4). Driven by earnings day reaction, 20D post-earnings drift, and post-earnings volume character.
Combined Score
6 / 12
1 Price Structure & Trend Potential Bottoming · Death Cross
2 Momentum Accelerating
3 Relative Strength vs. SPY Strong Outperformance
4 Institutional Footprint & Volume Strong Accumulation
5 Volatility Normal
6 Key Price Levels Range · Vol Falling
7 Earnings Reaction History Inconsistent
8 How the Verdict Is Derived Three Pillars
Core Cache Last Updated: 8/6/2026