Regeneron Pharmaceuticals (REGN)
Market Price (11/6/2025): $652.75 | Market Cap: $67.6 BilSector: Health Care | Industry: Biotechnology
Regeneron Pharmaceuticals (REGN)
Market Price (11/6/2025): $652.75Market Cap: $67.6 BilSector: Health CareIndustry: Biotechnology
Investment Highlights
Why It Matters
Which of these 2 stories sounds closer for this stock?
1. Generates cash flow
The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.
2. Riding a trend
Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow
| Attractive yieldTotal YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 7.3%, ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is 3.2%, FCF Yield is 5.8% | Weak multi-year price returns2Y Excs Rtn is -79%, 3Y Excs Rtn is -89% | |
| Attractive operating marginsOp Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 27% | ||
| Attractive cash flow generationCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 36%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 27%, CFO LTM is 5.1 Bil, FCF LTM is 3.9 Bil | ||
| Low stock price volatilityVol 12M is 41% |
| Attractive yieldTotal YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 7.3%, ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is 3.2%, FCF Yield is 5.8% |
| Attractive operating marginsOp Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 27% |
| Attractive cash flow generationCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 36%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 27%, CFO LTM is 5.1 Bil, FCF LTM is 3.9 Bil |
| Low stock price volatilityVol 12M is 41% |
| Weak multi-year price returns2Y Excs Rtn is -79%, 3Y Excs Rtn is -89% |
Market Valuation & Key Metrics
REGN Stock
Return vs. Risk
Price Returns Compared
| 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total [1] | |
|---|---|---|---|---|---|---|---|
| Returns | |||||||
| REGN Return | 29% | 31% | 14% | 22% | -19% | -9% | 72% |
| Peers Return | -2% | 2% | 20% | -5% | -12% | 11% | 10% |
| S&P 500 Return | 16% | 27% | -19% | 24% | 23% | 16% | 110% |
Monthly Win Rates [3] | |||||||
| REGN Win Rate | 50% | 67% | 50% | 58% | 50% | 50% | |
| Peers Win Rate | 50% | 47% | 53% | 42% | 45% | 52% | |
| S&P 500 Win Rate | 58% | 75% | 42% | 67% | 75% | 70% | |
Max Drawdowns [4] | |||||||
| REGN Max Drawdown | -10% | -8% | -13% | -6% | -20% | -32% | |
| Peers Max Drawdown | -22% | -13% | -13% | -21% | -25% | -14% | |
| S&P 500 Max Drawdown | -31% | -1% | -25% | -1% | -2% | -15% | |
[1] Cumulative total returns since the beginning of 2020
[2] Peers: AMGN, GILD, BIIB, BMRN, JAZZ. See REGN Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 11/5/2025 (YTD)
How Low Can It Go
| Event | REGN | S&P 500 |
|---|---|---|
| 2022 Inflation Shock | ||
| % Loss | -25.8% | -25.4% |
| % Gain to Breakeven | 34.7% | 34.1% |
| Time to Breakeven | 112 days | 464 days |
| 2020 Covid Pandemic | ||
| % Loss | -27.3% | -33.9% |
| % Gain to Breakeven | 37.6% | 51.3% |
| Time to Breakeven | 233 days | 148 days |
| 2018 Correction | ||
| % Loss | -48.1% | -19.8% |
| % Gain to Breakeven | 92.5% | 24.7% |
| Time to Breakeven | 202 days | 120 days |
| 2008 Global Financial Crisis | ||
| % Loss | -57.9% | -56.8% |
| % Gain to Breakeven | 137.3% | 131.3% |
| Time to Breakeven | 329 days | 1480 days |
Compare to AMGN, GILD, BIIB, BMRN, JAZZ
In The Past
Regeneron Pharmaceuticals's stock fell -25.8% during the 2022 Inflation Shock from a high on 4/8/2022. A -25.8% loss requires a 34.7% gain to breakeven.
Preserve Wealth
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Asset Allocation
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Latest Trefis Analyses
Trade Ideas
Select past ideas related to REGN. For more, see Trefis Trade Ideas.
| Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
|---|---|---|---|---|---|---|---|
| 10312025 | GDRX | GoodRx | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | -1.2% | -1.2% | -3.3% |
| 10312025 | DXCM | DexCom | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | 1.8% | 1.8% | 0.0% |
| 10242025 | ACHC | Acadia Healthcare | Dip Buy | DB | P/E OPMDip Buy with Low PE and High MarginBuying dips for companies with tame PE and meaningfully high operating margin | -11.6% | -11.6% | -11.7% |
| 10102025 | PBH | Prestige Consumer Healthcare | Dip Buy | DB | P/E OPMDip Buy with Low PE and High MarginBuying dips for companies with tame PE and meaningfully high operating margin | -1.9% | -1.9% | -1.9% |
| 10032025 | REGN | Regeneron Pharmaceuticals | Dip Buy | DB | P/E OPMDip Buy with Low PE and High MarginBuying dips for companies with tame PE and meaningfully high operating margin | 7.4% | 7.4% | -7.0% |
| 03312025 | REGN | Regeneron Pharmaceuticals | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | -11.3% | 1.9% | -23.7% |
| 05312019 | REGN | Regeneron Pharmaceuticals | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 22.3% | 103.1% | -9.4% |
| Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
|---|---|---|---|---|---|---|---|
| 10312025 | GDRX | GoodRx | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | -1.2% | -1.2% | -3.3% |
| 10312025 | DXCM | DexCom | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | 1.8% | 1.8% | 0.0% |
| 10242025 | ACHC | Acadia Healthcare | Dip Buy | DB | P/E OPMDip Buy with Low PE and High MarginBuying dips for companies with tame PE and meaningfully high operating margin | -11.6% | -11.6% | -11.7% |
| 10102025 | PBH | Prestige Consumer Healthcare | Dip Buy | DB | P/E OPMDip Buy with Low PE and High MarginBuying dips for companies with tame PE and meaningfully high operating margin | -1.9% | -1.9% | -1.9% |
| 10032025 | REGN | Regeneron Pharmaceuticals | Dip Buy | DB | P/E OPMDip Buy with Low PE and High MarginBuying dips for companies with tame PE and meaningfully high operating margin | 7.4% | 7.4% | -7.0% |
| 03312025 | REGN | Regeneron Pharmaceuticals | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | -11.3% | 1.9% | -23.7% |
| 05312019 | REGN | Regeneron Pharmaceuticals | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 22.3% | 103.1% | -9.4% |
Research & Analysis
Invest in Strategies
Wealth Management
Peer Comparisons for Regeneron Pharmaceuticals
Financials
| Median | |
|---|---|
| Name | |
| Mkt Price | 145.32 |
| Mkt Cap | 44.6 |
| Rev LTM | 12,157 |
| Op Inc LTM | 3,150 |
| FCF LTM | 3,072 |
| FCF 3Y Avg | 2,769 |
| CFO LTM | 3,762 |
| CFO 3Y Avg | 3,414 |
Growth & Margins
| Median | |
|---|---|
| Name | |
| Rev Chg LTM | 4.6% |
| Rev Chg 3Y Avg | 3.6% |
| Rev Chg Q | 2.5% |
| QoQ Delta Rev Chg LTM | 0.6% |
| Op Mgn LTM | 24.4% |
| Op Mgn 3Y Avg | 23.9% |
| QoQ Delta Op Mgn LTM | 0.2% |
| CFO/Rev LTM | 33.2% |
| CFO/Rev 3Y Avg | 32.0% |
| FCF/Rev LTM | 28.8% |
| FCF/Rev 3Y Avg | 27.8% |
Valuation
| Median | |
|---|---|
| Name | |
| Mkt Cap | 44.6 |
| P/S | 4.0 |
| P/EBIT | 13.8 |
| P/E | 17.0 |
| P/CFO | 12.1 |
| Total Yield | 6.9% |
| Dividend Yield | 0.2% |
| FCF Yield 3Y Avg | 6.3% |
| D/E | 0.2 |
| Net D/E | 0.1 |
Returns
| Median | |
|---|---|
| Name | |
| 1M Rtn | 3.8% |
| 3M Rtn | 14.7% |
| 6M Rtn | 21.8% |
| 12M Rtn | -4.9% |
| 3Y Rtn | -9.4% |
| 1M Excs Rtn | 1.7% |
| 3M Excs Rtn | 7.1% |
| 6M Excs Rtn | 1.1% |
| 12M Excs Rtn | -22.7% |
| 3Y Excs Rtn | -84.6% |
Segment Financials
Revenue by Segment
| $ Mil | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|
| EYLEA ® | 5,720 | 6,265 | 5,792 | 4,947 | 4,644 |
| Collaboration revenue | 5,503 | 4,914 | |||
| Libtayo ® | 539 | 374 | 306 | 271 | 176 |
| Other revenue | 536 | 365 | 281 | 557 | 174 |
| Libtayo | 324 | 73 | |||
| Praluent ® | 182 | 130 | 170 | 151 | |
| EYLEA HD ® | 166 | 0 | |||
| Evkeeza ® | 77 | 49 | 18 | ||
| Inmazeb ® | 70 | 3 | |||
| ARCALYST ® | 0 | 2 | 13 | 14 | |
| REGEN-COV ® | 0 | 5,828 | 186 | ||
| Bayer | 1,409 | 1,186 | 1,146 | ||
| Roche | 362 | ||||
| Sanofi | 1,902 | 1,186 | 404 | ||
| Total | 13,117 | 12,173 | 16,072 | 8,497 | 6,558 |
Returns Analyses
Earnings Returns History
Expand for More| Forward Returns | |||
|---|---|---|---|
| Earnings Date | 1D Returns | 5D Returns | 21D Returns |
| 10/28/2025 | 11.8% | 9.7% | |
| 8/1/2025 | 2.5% | 2.6% | 6.6% |
| 4/29/2025 | -6.9% | -1.2% | -3.0% |
| 1/13/2025 | 2.9% | -2.2% | -4.5% |
| 10/31/2024 | -9.2% | -11.5% | -18.7% |
| 8/1/2024 | 1.3% | -1.1% | 9.2% |
| 5/2/2024 | 3.8% | 5.8% | 8.5% |
| 2/2/2024 | -1.3% | -1.2% | 1.4% |
| ... | |||
| SUMMARY STATS | |||
| # Positive | 18 | 12 | 14 |
| # Negative | 7 | 13 | 11 |
| Median Positive | 3.6% | 5.9% | 7.6% |
| Median Negative | -3.7% | -2.2% | -5.2% |
| Max Positive | 11.8% | 10.7% | 32.9% |
| Max Negative | -9.2% | -11.5% | -18.7% |
SEC Filings
Expand for More| Report Date | Filing Date | Filing |
|---|---|---|
| 9302025 | 10282025 | 10-Q 9/30/2025 |
| 6302025 | 8012025 | 10-Q 6/30/2025 |
| 3312025 | 4292025 | 10-Q 3/31/2025 |
| 12312024 | 2052025 | 10-K 12/31/2024 |
| 9302024 | 10312024 | 10-Q 9/30/2024 |
| 6302024 | 8012024 | 10-Q 6/30/2024 |
| 3312024 | 5022024 | 10-Q 3/31/2024 |
| 12312023 | 2052024 | 10-K 12/31/2023 |
| 9302023 | 11022023 | 10-Q 9/30/2023 |
| 6302023 | 8032023 | 10-Q 6/30/2023 |
| 3312023 | 5042023 | 10-Q 3/31/2023 |
| 12312022 | 2062023 | 10-K 12/31/2022 |
| 9302022 | 11032022 | 10-Q 9/30/2022 |
| 6302022 | 8032022 | 10-Q 6/30/2022 |
| 3312022 | 5042022 | 10-Q 3/31/2022 |
| 12312021 | 2072022 | 10-K 12/31/2021 |
Industry Resources
External Quote Links
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