Tearsheet

Regeneron Pharmaceuticals (REGN)


Market Price (9/17/2025): $574.39 | Market Cap: $60.4 Bil
Sector: Health Care | Industry: Biotechnology

Regeneron Pharmaceuticals (REGN)


Market Price (9/17/2025): $574.39
Market Cap: $60.4 Bil
Sector: Health Care
Industry: Biotechnology

Investment Highlights

0 Attractive yield
Total YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 7.7%, ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is 3.2%, FCF Yield is 5.9%
Weak multi-year price returns
2Y Excs Rtn is -79%, 3Y Excs Rtn is -83%
Weak revenue growth
Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is 0.3%
1 Attractive operating margins
Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 27%
  
2 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 33%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 25%, CFO LTM is 4.7 Bil, FCF LTM is 3.6 Bil
  
3 Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -28%
  
4 Low stock price volatility
Vol 12M is 39%
  
0 Attractive yield
Total YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 7.7%, ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is 3.2%, FCF Yield is 5.9%
1 Attractive operating margins
Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 27%
2 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 33%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 25%, CFO LTM is 4.7 Bil, FCF LTM is 3.6 Bil
3 Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -28%
4 Low stock price volatility
Vol 12M is 39%
5 Weak multi-year price returns
2Y Excs Rtn is -79%, 3Y Excs Rtn is -83%
6 Weak revenue growth
Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is 0.3%

Market Valuation

 9/17/252024202320222021
Share Price CYE$574.39$709.29$874.54$718.41$628.82
Market Cap CYE ($ Bil)60.476.393.176.766.8
Total Debt ($ Bil)2.72.72.72.72.7
Total Cash ($ Bil)7.59.010.87.75.7
Enterprise Value ($ Bil)55.679.095.879.469.5
Valuation Ratios     
P/S TTM4.25.47.16.34.2
P/EBIT TTM12.315.921.915.77.1
P/E TTM13.517.423.717.88.3
Sector Ratios     
P/S TTM (Sector)3.73.64.14.57.3
P/EBIT TTM (Sector)-1.6-1.3-1.4-1.3-2.9
P/E TTM (Sector)-1.8-1.5-1.5-1.3-2.9
 9/17/2520242023
Share Price CYE$574.39$709.29$874.54
Market Cap CYE ($ Bil)60.476.393.1
Total Debt ($ Bil)2.72.72.7
Total Cash ($ Bil)7.59.010.8
Enterprise Value ($ Bil)55.679.095.8
Valuation Ratios   
P/S TTM4.25.47.1
P/EBIT TTM12.315.921.9
P/E TTM13.517.423.7
Sector Ratios   
P/S TTM (Sector)3.73.64.1
P/EBIT TTM (Sector)-1.6-1.3-1.4
P/E TTM (Sector)-1.8-1.5-1.5

Business Description

Regeneron Pharmaceuticals, Inc. discovers, invents, develops, manufactures, and commercializes medicines for treating various diseases worldwide. The company's products include EYLEA injection to treat wet age-related macular degeneration and diabetic macular edema; myopic choroidal neovascularization; and diabetic retinopathy, as well as macular edema following retinal vein occlusion, including macular edema following central retinal vein occlusion and macular edema following branch retinal vein occlusion. Show more

Price Returns Compared

Expand for Detailed View

 202020212022202320242025Total [1]
Returns
REGN Return29%31%14%22%-19%-19%50%
Peers Return1%13%20%-0%-8%6%32%
S&P 500 Return16%27%-19%24%23%12%104%

[1] Cumulative total returns since the beginning of 2020
[2] Peers: AMGN, GILD, BIIB, BMRN, ABBV. See REGN Returns vs. Peers.
[3] 2025 data is for the year up to 9/16/2025 (YTD)

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Financials

REGNAMGNGILDBIIBBMRNABBVMedian
NameRegenero.Amgen Gilead S.Biogen BioMarin.AbbVie  
Mkt Price575.06273.08110.86143.6853.94216.26179.97
Mkt Cap60.4146.9138.021.010.4382.399.2
Rev LTM14,21434,91728,8629,8163,06458,32821,538
Op Inc LTM3,8418,19210,7972,27477613,6956,016
FCF LTM3,55610,6059,3692,29669118,2396,463
FCF 3Y Avg3,2488,5908,3971,66731520,2735,823
CFO LTM4,74412,0139,8682,58276719,2837,306
CFO 3Y Avg4,5189,7538,9491,96841921,1546,733

Growth & Margins

REGNAMGNGILDBIIBBMRNABBVMedian
NameRegenero.Amgen Gilead S.Biogen BioMarin.AbbVie  
Rev Chg LTM5.4%12.9%3.8%1.6%18.4%6.1%5.7%
Rev Chg 3Y Avg0.3%10.0%1.6%-3.1%17.0%0.6%1.1%
Rev Chg Q3.6%9.4%1.8%6.1%15.9%6.6%6.4%
QoQ Delta Rev Chg LTM0.9%2.3%0.4%1.5%3.8%1.7%1.6%
Op Mgn LTM27.0%23.5%37.4%23.2%25.3%23.5%24.4%
Op Mgn 3Y Avg30.1%26.4%39.2%23.4%14.0%27.2%26.8%
QoQ Delta Op Mgn LTM-0.2%1.6%-0.0%0.2%4.3%1.0%0.6%
CFO/Rev LTM33.4%34.4%34.2%26.3%25.0%33.1%33.2%
CFO/Rev 3Y Avg33.6%32.0%31.9%20.0%15.0%37.5%31.9%
FCF/Rev LTM25.0%30.4%32.5%23.4%22.6%31.3%27.7%
FCF/Rev 3Y Avg24.1%28.2%30.0%16.9%10.9%36.0%26.1%

Valuation

REGNAMGNGILDBIIBBMRNABBVMedian
NameRegenero.Amgen Gilead S.Biogen BioMarin.AbbVie  
Mkt Cap60.4146.9138.021.010.4382.399.2
P/S4.34.24.82.13.46.64.2
P/EBIT12.314.216.810.512.264.913.2
P/E13.622.221.914.215.7101.618.8
P/CFO12.712.214.08.113.519.813.1
Total Yield7.7%7.9%7.4%7.0%6.3%3.9%7.2%
Dividend Yield0.3%3.4%2.9%0.0%0.0%3.0%1.6%
FCF Yield 3Y Avg4.4%6.2%8.0%6.6%2.7%7.3%6.4%
D/E0.00.40.20.30.10.20.2
Net D/E-0.10.30.10.2-0.10.20.2

Returns

REGNAMGNGILDBIIBBMRNABBVMedian
NameRegenero.Amgen Gilead S.Biogen BioMarin.AbbVie  
1M Rtn-0.8%-7.9%-5.7%3.7%-6.3%4.6%-3.2%
3M Rtn13.2%-5.1%3.4%13.5%-1.9%17.6%8.3%
6M Rtn-13.3%-12.8%2.0%0.4%-24.6%2.9%-6.2%
12M Rtn-49.9%-15.8%37.3%-28.0%-22.8%14.4%-19.3%
3Y Rtn-18.7%30.0%88.1%-31.0%-38.9%68.0%5.7%
1M Excs Rtn-3.2%-10.3%-8.1%1.2%-8.7%2.2%-5.7%
3M Excs Rtn0.7%-16.4%-8.8%0.1%-13.6%4.8%-4.3%
6M Excs Rtn-31.4%-28.9%-16.3%-16.3%-41.0%-13.8%-22.6%
12M Excs Rtn-68.5%-32.6%20.5%-45.5%-54.1%-2.6%-39.0%
3Y Excs Rtn-82.7%-41.1%28.7%-94.6%-104.4%8.7%-61.9%

Financials

Segment Financials

Revenue by Segment

$ Mil20242023202220212020
EYLEA ®5,7206,2655,7924,9474,644
Collaboration revenue5,5034,9143,673  
Libtayo ®539374306271176
Other revenue536365281557174
Libtayo324730  
Praluent ®182130170151 
EYLEA HD ®16600  
Evkeeza ®774918  
Inmazeb ®7030  
ARCALYST ®  21314
REGEN-COV ®  5,828186 
Bayer   1,1861,146
Sanofi   1,186404
Total13,11712,17316,0728,4976,558


Price Behavior

Short Interest

Short Interest: As Of Date8292025
Short Interest: Shares Quantity2,827,689
Short Interest: % Change Since 815202520.4%
Average Daily Volume959,124
Days-to-Cover Short Interest2.95
Basic Shares Quantity105,100,000
Short % of Basic Shares2.7%

Earnings Returns History

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 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/1/20252.5%2.6%6.6%
4/29/2025-6.9%-1.2%-3.0%
1/13/20252.9%-2.2%-4.5%
10/31/2024-9.2%-11.5%-18.7%
8/1/20241.3%-1.1%9.2%
5/2/20243.8%5.8%8.5%
2/2/2024-1.3%-1.2%1.4%
11/2/20233.5%4.0%3.0%
...
SUMMARY STATS   
# Positive181114
# Negative71411
Median Positive3.4%5.8%7.6%
Median Negative-3.7%-1.9%-4.5%
Max Positive6.9%10.7%32.9%
Max Negative-9.2%-11.5%-18.7%

SEC Filings

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Report DateFiling DateFiling
6302025801202510-Q 6/30/2025
3312025429202510-Q 3/31/2025
12312024205202510-K 12/31/2024
93020241031202410-Q 9/30/2024
6302024801202410-Q 6/30/2024
3312024502202410-Q 3/31/2024
12312023205202410-K 12/31/2023
93020231102202310-Q 9/30/2023
6302023803202310-Q 6/30/2023
3312023504202310-Q 3/31/2023
12312022206202310-K 12/31/2022
93020221103202210-Q 9/30/2022
6302022803202210-Q 6/30/2022
3312022504202210-Q 3/31/2022
12312021207202210-K 12/31/2021
93020211104202110-Q 9/30/2021

Insider Activity

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 OwnerTitleFiling DateActionPriceSharesTransacted
Value
Value of
Held Shares
Form
0RYAN ARTHUR F 10032024Sell1041.3533,12418,410,027Form
1RYAN ARTHUR F 9052024Sell1166.5244,66620,738,393Form