Pfizer (PFE)
Market Price (10/16/2025): $24.43 | Market Cap: $138.9 BilSector: Health Care | Industry: Pharmaceuticals
Pfizer (PFE)
Market Price (10/16/2025): $24.43Market Cap: $138.9 BilSector: Health CareIndustry: Pharmaceuticals
Investment Highlights
Attractive yieldTotal YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 13%, Dividend Yield is 5.2%, ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is 8.5%, FCF Yield is 9.0% | Weak multi-year price returns2Y Excs Rtn is -69%, 3Y Excs Rtn is -116% | Weak revenue growthRev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -12% |
Attractive operating marginsOp Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 26% | ||
Attractive cash flow generationCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 24%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 19%, CFO LTM is 15 Bil, FCF LTM is 12 Bil | ||
Low stock price volatilityVol 12M is 26% |
Attractive yieldTotal YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 13%, Dividend Yield is 5.2%, ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is 8.5%, FCF Yield is 9.0% |
Attractive operating marginsOp Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 26% |
Attractive cash flow generationCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 24%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 19%, CFO LTM is 15 Bil, FCF LTM is 12 Bil |
Low stock price volatilityVol 12M is 26% |
Weak multi-year price returns2Y Excs Rtn is -69%, 3Y Excs Rtn is -116% |
Weak revenue growthRev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -12% |
Market Valuation & Key Metrics
PFE Stock
Return vs. Risk
Price Returns Compared
2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total [1] | |
---|---|---|---|---|---|---|---|
Returns | |||||||
PFE Return | -2% | 67% | -10% | -41% | -2% | -3% | -17% |
Peers Return | 9% | 21% | 17% | 5% | 9% | 9% | 91% |
S&P 500 Return | 16% | 27% | -19% | 24% | 23% | 13% | 103% |
Monthly Win Rates [3] | |||||||
PFE Win Rate | 33% | 75% | 42% | 17% | 33% | 44% | |
Peers Win Rate | 52% | 55% | 60% | 45% | 48% | 56% | |
S&P 500 Win Rate | 58% | 75% | 42% | 67% | 75% | 67% | |
Max Drawdowns [4] | |||||||
PFE Max Drawdown | -27% | -8% | -28% | -47% | -11% | -17% | |
Peers Max Drawdown | -20% | -7% | -10% | -17% | -10% | -13% | |
S&P 500 Max Drawdown | -31% | -1% | -25% | -1% | -2% | -15% | |
[1] Cumulative total returns since the beginning of 2020
[2] Peers: RHHBY, LLY, JNJ, MRK, BMY. See PFE Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 10/15/2025 (YTD)
Downturns Compared
Event | PFE | S&P 500 |
---|---|---|
2022 Inflation Shock | ||
% Loss | -57.3% | -25.4% |
% Gain to Breakeven | 134.4% | 34.1% |
Time to Breakeven | Not Fully Recovered days | 464 days |
2020 Covid Pandemic | ||
% Loss | -30.0% | -33.9% |
% Gain to Breakeven | 42.9% | 51.3% |
Time to Breakeven | 254 days | 148 days |
2018 Correction | ||
% Loss | -25.9% | -19.8% |
% Gain to Breakeven | 35.0% | 24.7% |
Time to Breakeven | 727 days | 120 days |
2008 Global Financial Crisis | ||
% Loss | -57.9% | -56.8% |
% Gain to Breakeven | 137.4% | 131.3% |
Time to Breakeven | 1429 days | 1480 days |
How Low Can It Go?
Pfizer's stock fell -57.3% during the 2022 Inflation Shock from a high on 12/16/2021. A -57.3% loss requires a 134.4% gain to breakeven.
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Latest Trefis Analyses
Trade Ideas
Select past ideas related to PFE. For more, see Trefis Trade Ideas.
Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
---|---|---|---|---|---|---|---|
09302025 | ADMA | ADMA Biologics | Dip Buy | DB | P/E OPMDip Buy with Low PE and High MarginBuying dips for companies with tame PE and meaningfully high operating margin | 2.9% | 2.9% | -4.6% |
09302025 | REGN | Regeneron Pharmaceuticals | Dip Buy | DB | P/E OPMDip Buy with Low PE and High MarginBuying dips for companies with tame PE and meaningfully high operating margin | 2.5% | 2.5% | -0.8% |
09262025 | HAE | Haemonetics | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 0.9% | 0.9% | -0.1% |
09192025 | WAT | Waters | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | 10.5% | 10.5% | -4.3% |
09052025 | ISRG | Intuitive Surgical | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | -6.7% | -6.7% | -8.0% |
05312025 | PFE | Pfizer | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | 5.6% | 5.6% | -1.6% |
02282023 | PFE | Pfizer | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | -8.9% | -29.9% | -33.3% |
08312022 | PFE | Pfizer | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | -9.6% | -18.6% | -19.5% |
02282022 | PFE | Pfizer | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | 0.1% | -10.6% | -10.6% |
03312020 | PFE | Pfizer | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | 13.0% | 15.6% | -2.7% |
09302019 | PFE | Pfizer | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | -7.3% | 4.7% | -19.1% |
Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
---|---|---|---|---|---|---|---|
09302025 | ADMA | ADMA Biologics | Dip Buy | DB | P/E OPMDip Buy with Low PE and High MarginBuying dips for companies with tame PE and meaningfully high operating margin | 2.9% | 2.9% | -4.6% |
09302025 | REGN | Regeneron Pharmaceuticals | Dip Buy | DB | P/E OPMDip Buy with Low PE and High MarginBuying dips for companies with tame PE and meaningfully high operating margin | 2.5% | 2.5% | -0.8% |
09262025 | HAE | Haemonetics | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 0.9% | 0.9% | -0.1% |
09192025 | WAT | Waters | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | 10.5% | 10.5% | -4.3% |
09052025 | ISRG | Intuitive Surgical | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | -6.7% | -6.7% | -8.0% |
05312025 | PFE | Pfizer | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | 5.6% | 5.6% | -1.6% |
02282023 | PFE | Pfizer | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | -8.9% | -29.9% | -33.3% |
08312022 | PFE | Pfizer | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | -9.6% | -18.6% | -19.5% |
02282022 | PFE | Pfizer | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | 0.1% | -10.6% | -10.6% |
03312020 | PFE | Pfizer | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | 13.0% | 15.6% | -2.7% |
09302019 | PFE | Pfizer | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | -7.3% | 4.7% | -19.1% |
Research & Analysis
Invest in Strategies
Wealth Management
Peer Comparisons for Pfizer
Financials
Median | |
---|---|
Name | |
Mkt Price | 64.30 |
Mkt Cap | 211.1 |
Rev LTM | 63,616 |
Op Inc LTM | 19,821 |
FCF LTM | 13,086 |
FCF 3Y Avg | 12,225 |
CFO LTM | 15,188 |
CFO 3Y Avg | 13,419 |
Growth & Margins
Median | |
---|---|
Name | |
Rev Chg LTM | 4.7% |
Rev Chg 3Y Avg | 3.7% |
Rev Chg Q | 5.8% |
QoQ Delta Rev Chg LTM | 1.5% |
Op Mgn LTM | 26.1% |
Op Mgn 3Y Avg | 22.6% |
QoQ Delta Op Mgn LTM | 1.8% |
CFO/Rev LTM | 25.4% |
CFO/Rev 3Y Avg | 25.7% |
FCF/Rev LTM | 19.5% |
FCF/Rev 3Y Avg | 19.6% |
Valuation
Median | |
---|---|
Name | |
Mkt Cap | 211.1 |
P/S | 3.3 |
P/EBIT | 10.9 |
P/E | 16.3 |
P/CFO | 11.4 |
Total Yield | 11.6% |
Dividend Yield | 3.8% |
FCF Yield 3Y Avg | 5.1% |
D/E | 0.2 |
Net D/E | 0.1 |
Returns
Median | |
---|---|
Name | |
1M Rtn | 5.8% |
3M Rtn | 4.0% |
6M Rtn | 13.8% |
12M Rtn | -10.1% |
3Y Rtn | 13.6% |
1M Excs Rtn | 4.9% |
3M Excs Rtn | 0.6% |
6M Excs Rtn | -12.5% |
12M Excs Rtn | -25.3% |
3Y Excs Rtn | -69.1% |
Comparison Analyses
Returns Analyses
Earnings Returns History
Expand for MoreForward Returns | |||
---|---|---|---|
Earnings Date | 1D Returns | 5D Returns | 21D Returns |
8/5/2025 | 5.2% | 4.5% | 5.4% |
4/29/2025 | 3.2% | 3.6% | 2.5% |
2/4/2025 | -1.3% | -1.3% | -1.0% |
10/29/2024 | -1.4% | -3.8% | -9.3% |
7/30/2024 | 2.2% | -3.2% | -6.2% |
5/1/2024 | 6.1% | 8.4% | 11.7% |
1/30/2024 | -1.7% | -3.3% | -1.6% |
10/13/2023 | 3.6% | -4.5% | -8.5% |
... | |||
SUMMARY STATS | |||
# Positive | 13 | 11 | 10 |
# Negative | 11 | 13 | 14 |
Median Positive | 3.2% | 3.2% | 7.0% |
Median Negative | -1.4% | -3.3% | -5.1% |
Max Positive | 6.1% | 11.7% | 26.4% |
Max Negative | -5.0% | -6.4% | -12.7% |
SEC Filings
Expand for MoreReport Date | Filing Date | Filing |
---|---|---|
6302025 | 8052025 | 10-Q 6/29/2025 |
3312025 | 5052025 | 10-Q 3/30/2025 |
12312024 | 2272025 | 10-K 12/31/2024 |
9302024 | 11042024 | 10-Q 9/29/2024 |
6302024 | 8052024 | 10-Q 6/30/2024 |
3312024 | 5082024 | 10-Q 3/31/2024 |
12312023 | 2222024 | 10-K 12/31/2023 |
9302023 | 11082023 | 10-Q 10/1/2023 |
6302023 | 8092023 | 10-Q 7/2/2023 |
3312023 | 5102023 | 10-Q 4/2/2023 |
12312022 | 2232023 | 10-K 12/31/2022 |
9302022 | 11092022 | 10-Q 10/2/2022 |
6302022 | 8102022 | 10-Q 7/3/2022 |
3312022 | 5112022 | 10-Q 4/3/2022 |
12312021 | 2242022 | 10-K 12/31/2021 |
9302021 | 11122021 | 10-Q 10/3/2021 |
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