Tearsheet

Pfizer (PFE)


Market Price (10/16/2025): $24.43 | Market Cap: $138.9 Bil
Sector: Health Care | Industry: Pharmaceuticals

Pfizer (PFE)


Market Price (10/16/2025): $24.43
Market Cap: $138.9 Bil
Sector: Health Care
Industry: Pharmaceuticals

Investment Highlights


0 Attractive yield
Total YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 13%, Dividend Yield is 5.2%, ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is 8.5%, FCF Yield is 9.0%
Weak multi-year price returns
2Y Excs Rtn is -69%, 3Y Excs Rtn is -116%
Weak revenue growth
Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -12%
1 Attractive operating margins
Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 26%
  
2 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 24%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 19%, CFO LTM is 15 Bil, FCF LTM is 12 Bil
  
3 Low stock price volatility
Vol 12M is 26%
  
0 Attractive yield
Total YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 13%, Dividend Yield is 5.2%, ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is 8.5%, FCF Yield is 9.0%
1 Attractive operating margins
Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 26%
2 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 24%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 19%, CFO LTM is 15 Bil, FCF LTM is 12 Bil
3 Low stock price volatility
Vol 12M is 26%
4 Weak multi-year price returns
2Y Excs Rtn is -69%, 3Y Excs Rtn is -116%
5 Weak revenue growth
Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -12%

Market Valuation & Key Metrics

PFE Stock


Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
PFE Return-2%67%-10%-41%-2%-3%-17%
Peers Return9%21%17%5%9%9%91%
S&P 500 Return16%27%-19%24%23%13%103%

Monthly Win Rates [3]
PFE Win Rate33%75%42%17%33%44% 
Peers Win Rate52%55%60%45%48%56% 
S&P 500 Win Rate58%75%42%67%75%67% 

Max Drawdowns [4]
PFE Max Drawdown-27%-8%-28%-47%-11%-17% 
Peers Max Drawdown-20%-7%-10%-17%-10%-13% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: RHHBY, LLY, JNJ, MRK, BMY. See PFE Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 10/15/2025 (YTD)

Downturns Compared

Unique KeyEventPFES&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-57.3%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven134.4%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-30.0%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven42.9%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven254 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-25.9%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven35.0%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven727 days120 days
2008 Global Financial Crisis2008 Global Financial Crisis  
2008 Global Financial Crisis% Loss% Loss-57.9%-56.8%
2008 Global Financial Crisis% Gain to Breakeven% Gain to Breakeven137.4%131.3%
2008 Global Financial CrisisTime to BreakevenTime to Breakeven1429 days1480 days


How Low Can It Go?

Pfizer's stock fell -57.3% during the 2022 Inflation Shock from a high on 12/16/2021. A -57.3% loss requires a 134.4% gain to breakeven.

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Asset Allocation

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Better Bets than Pfizer (PFE)

Latest Trefis Analyses

Trade Ideas

Select past ideas related to PFE. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
ADMA_9302025_Dip_Buyer_ValueBuy09302025ADMAADMA BiologicsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
2.9%2.9%-4.6%
REGN_9302025_Dip_Buyer_ValueBuy09302025REGNRegeneron PharmaceuticalsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
2.5%2.5%-0.8%
HAE_9262025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG09262025HAEHaemoneticsDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
0.9%0.9%-0.1%
WAT_9192025_Monopoly_xInd_xCD_Getting_Cheaper09192025WATWatersMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
10.5%10.5%-4.3%
ISRG_9052025_Monopoly_xInd_xCD_Getting_Cheaper09052025ISRGIntuitive SurgicalMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-6.7%-6.7%-8.0%
PFE_5312025_Monopoly_xInd_xCD_Getting_Cheaper05312025PFEPfizerMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
5.6%5.6%-1.6%
PFE_2282023_Monopoly_xInd_xCD_Getting_Cheaper02282023PFEPfizerMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-8.9%-29.9%-33.3%
PFE_8312022_Monopoly_xInd_xCD_Getting_Cheaper08312022PFEPfizerMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-9.6%-18.6%-19.5%
PFE_2282022_Monopoly_xInd_xCD_Getting_Cheaper02282022PFEPfizerMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
0.1%-10.6%-10.6%
PFE_3312020_Monopoly_xInd_xCD_Getting_Cheaper03312020PFEPfizerMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
13.0%15.6%-2.7%
PFE_9302019_Monopoly_xInd_xCD_Getting_Cheaper09302019PFEPfizerMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-7.3%4.7%-19.1%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
ADMA_9302025_Dip_Buyer_ValueBuy09302025ADMAADMA BiologicsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
2.9%2.9%-4.6%
REGN_9302025_Dip_Buyer_ValueBuy09302025REGNRegeneron PharmaceuticalsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
2.5%2.5%-0.8%
HAE_9262025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG09262025HAEHaemoneticsDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
0.9%0.9%-0.1%
WAT_9192025_Monopoly_xInd_xCD_Getting_Cheaper09192025WATWatersMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
10.5%10.5%-4.3%
ISRG_9052025_Monopoly_xInd_xCD_Getting_Cheaper09052025ISRGIntuitive SurgicalMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-6.7%-6.7%-8.0%
PFE_5312025_Monopoly_xInd_xCD_Getting_Cheaper05312025PFEPfizerMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
5.6%5.6%-1.6%
PFE_2282023_Monopoly_xInd_xCD_Getting_Cheaper02282023PFEPfizerMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-8.9%-29.9%-33.3%
PFE_8312022_Monopoly_xInd_xCD_Getting_Cheaper08312022PFEPfizerMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-9.6%-18.6%-19.5%
PFE_2282022_Monopoly_xInd_xCD_Getting_Cheaper02282022PFEPfizerMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
0.1%-10.6%-10.6%
PFE_3312020_Monopoly_xInd_xCD_Getting_Cheaper03312020PFEPfizerMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
13.0%15.6%-2.7%
PFE_9302019_Monopoly_xInd_xCD_Getting_Cheaper09302019PFEPfizerMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-7.3%4.7%-19.1%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for Pfizer

Financials

PFERHHBYLLYJNJMRKBMYMedian
NamePfizer Roche Eli LillyJohnson .Merck Bristol-. 
Mkt Price24.3944.48826.57191.1784.1143.6164.30
Mkt Cap138.7-742.2460.0211.188.6211.1
Rev LTM63,833-53,25890,62763,61647,63663,616
Op Inc LTM16,663-22,88222,22819,8217,87019,821
FCF LTM12,438--5016,39714,72213,08613,086
FCF 3Y Avg9,304--15616,92612,89912,22512,225
CFO LTM15,188-10,93823,02818,53414,31015,188
CFO 3Y Avg12,584-7,23022,24816,76613,41913,419

Growth & Margins

PFERHHBYLLYJNJMRKBMYMedian
NamePfizer Roche Eli LillyJohnson .Merck Bristol-. 
Rev Chg LTM13.5%-36.8%4.7%1.8%4.6%4.7%
Rev Chg 3Y Avg-12.4%-23.4%4.0%3.7%0.5%3.7%
Rev Chg Q10.3%-37.6%5.8%-1.9%-5.6%5.8%
QoQ Delta Rev Chg LTM2.2%-8.7%1.5%-0.5%-1.4%1.5%
Op Mgn LTM26.1%-43.0%24.5%31.2%16.5%26.1%
Op Mgn 3Y Avg20.2%-35.6%26.3%22.6%17.3%22.6%
QoQ Delta Op Mgn LTM1.8%-1.8%-0.2%-0.8%4.3%1.8%
CFO/Rev LTM23.8%-20.5%25.4%29.1%30.0%25.4%
CFO/Rev 3Y Avg18.8%-17.8%25.7%27.2%28.9%25.7%
FCF/Rev LTM19.5%--0.1%18.1%23.1%27.5%19.5%
FCF/Rev 3Y Avg13.8%-0.5%19.6%20.9%26.4%19.6%

Valuation

PFERHHBYLLYJNJMRKBMYMedian
NamePfizer Roche Eli LillyJohnson .Merck Bristol-. 
Mkt Cap138.7-742.2460.0211.188.6211.1
P/S2.2-13.95.13.31.93.3
P/EBIT10.4-41.816.310.310.910.9
P/E12.9-53.820.312.916.316.3
P/CFO9.1-67.920.011.46.211.4
Total Yield13.0%-2.5%7.6%11.6%11.7%11.6%
Dividend Yield5.2%-0.7%2.6%3.8%5.5%3.8%
FCF Yield 3Y Avg5.7%-0.1%4.5%5.1%12.4%5.1%
D/E0.4-0.10.10.20.60.2
Net D/E0.3-0.00.10.10.40.1

Returns

PFERHHBYLLYJNJMRKBMYMedian
NamePfizer Roche Eli LillyJohnson .Merck Bristol-. 
1M Rtn1.8%8.5%10.5%7.8%3.8%-4.6%5.8%
3M Rtn0.8%10.6%4.9%16.9%3.0%-6.3%4.0%
6M Rtn14.7%15.3%13.0%26.2%12.2%-9.3%13.8%
12M Rtn-11.3%16.8%-8.8%20.3%-21.8%-13.2%-10.1%
3Y Rtn-32.9%27.8%155.8%27.4%-0.2%-29.5%13.6%
1M Excs Rtn1.1%7.1%7.1%7.4%2.8%-5.6%4.9%
3M Excs Rtn-5.0%5.6%2.8%12.2%-1.7%-13.9%0.6%
6M Excs Rtn-10.9%-8.1%-14.0%2.8%-14.2%-34.0%-12.5%
12M Excs Rtn-25.2%2.6%-25.4%7.5%-35.2%-27.0%-25.3%
3Y Excs Rtn-115.8%-55.3%77.0%-54.1%-83.0%-111.9%-69.1%

Financials

Segment Financials

Revenue by Segment

$ Mil20242023202220212020
Biopharma58,23799,82679,55740,72438,013
Other business activities1,3161,3491,7319262,892
Total59,553101,17581,28841,65040,905


Price Behavior

Short Interest

Short Interest: As Of Date9302025
Short Interest: Shares Quantity113,954,344
Short Interest: % Change Since 91520250.9%
Average Daily Volume60,455,578
Days-to-Cover Short Interest1.88
Basic Shares Quantity5,685,000,000
Short % of Basic Shares2.0%

Earnings Returns History

Expand for More

 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/5/20255.2%4.5%5.4%
4/29/20253.2%3.6%2.5%
2/4/2025-1.3%-1.3%-1.0%
10/29/2024-1.4%-3.8%-9.3%
7/30/20242.2%-3.2%-6.2%
5/1/20246.1%8.4%11.7%
1/30/2024-1.7%-3.3%-1.6%
10/13/20233.6%-4.5%-8.5%
...
SUMMARY STATS   
# Positive131110
# Negative111314
Median Positive3.2%3.2%7.0%
Median Negative-1.4%-3.3%-5.1%
Max Positive6.1%11.7%26.4%
Max Negative-5.0%-6.4%-12.7%

SEC Filings

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Report DateFiling DateFiling
6302025805202510-Q 6/29/2025
3312025505202510-Q 3/30/2025
12312024227202510-K 12/31/2024
93020241104202410-Q 9/29/2024
6302024805202410-Q 6/30/2024
3312024508202410-Q 3/31/2024
12312023222202410-K 12/31/2023
93020231108202310-Q 10/1/2023
6302023809202310-Q 7/2/2023
3312023510202310-Q 4/2/2023
12312022223202310-K 12/31/2022
93020221109202210-Q 10/2/2022
6302022810202210-Q 7/3/2022
3312022511202210-Q 4/3/2022
12312021224202210-K 12/31/2021
93020211112202110-Q 10/3/2021

Insider Activity

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 OwnerTitleFiling DateActionPriceSharesTransacted
Value
Value of
Held Shares
Form
0BLAYLOCK RONALD E 2142025Buy25.6519,457499,072710,685Form
1Gottlieb Scott 10312024Buy28.241,00028,240282,400Form