Tearsheet

Investment Highlights Why It Matters Which of these 2 stories sounds closer for this stock?

1. Generates cash flow

The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.

2. Riding a trend

Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow


0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -44%
Weak multi-year price returns
2Y Excs Rtn is -128%, 3Y Excs Rtn is -166%
Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -3.3 Bil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -107%
1 Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -30%
Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 17%
Weak revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is -39%, Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -48%, Rev Chg QQuarterly Revenue Change % is -38%
2   Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -88%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -115%
3   Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -33%
0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -44%
1 Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -30%
2 Weak multi-year price returns
2Y Excs Rtn is -128%, 3Y Excs Rtn is -166%
3 Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 17%
4 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -3.3 Bil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -107%
5 Weak revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is -39%, Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -48%, Rev Chg QQuarterly Revenue Change % is -38%
6 Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -88%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -115%
7 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -33%

Market Valuation & Key Metrics

MRNA Stock


Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
MRNA Return434%143%-29%-45%-58%-37%33%
Peers Return11%-2%-2%-29%7%19%-4%
S&P 500 Return16%27%-19%24%23%13%106%

Monthly Win Rates [3]
MRNA Win Rate75%67%50%25%42%44% 
Peers Win Rate46%54%50%40%40%50% 
S&P 500 Win Rate58%75%42%67%75%67% 

Max Drawdowns [4]
MRNA Max Drawdown-9%0%-54%-61%-63%-43% 
Peers Max Drawdown-20%-33%-43%-41%-21%-34% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: PFE, ALNY, SRPT, CVAC, ACSB. See MRNA Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 10/17/2025 (YTD)

Downturns Compared

Unique KeyEventMRNAS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-85.7%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven597.0%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-42.7%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven74.5%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven69 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-56.7%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven131.2%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven205 days120 days


How Low Can It Go?

Moderna's stock fell -85.7% during the 2022 Inflation Shock from a high on 8/9/2021. A -85.7% loss requires a 597.0% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth over time.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

Better Bets than Moderna (MRNA)

Latest Trefis Analyses

Trade Ideas

Select past ideas related to MRNA. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
ADMA_9302025_Dip_Buyer_ValueBuy09302025ADMAADMA BiologicsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
-2.0%-2.0%-4.6%
REGN_9302025_Dip_Buyer_ValueBuy09302025REGNRegeneron PharmaceuticalsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
2.8%2.8%-0.8%
HAE_9262025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG09262025HAEHaemoneticsDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
4.3%4.3%-0.1%
WAT_9192025_Monopoly_xInd_xCD_Getting_Cheaper09192025WATWatersMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
11.2%11.2%-4.3%
ISRG_9052025_Monopoly_xInd_xCD_Getting_Cheaper09052025ISRGIntuitive SurgicalMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-4.4%-4.4%-8.0%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
ADMA_9302025_Dip_Buyer_ValueBuy09302025ADMAADMA BiologicsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
-2.0%-2.0%-4.6%
REGN_9302025_Dip_Buyer_ValueBuy09302025REGNRegeneron PharmaceuticalsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
2.8%2.8%-0.8%
HAE_9262025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG09262025HAEHaemoneticsDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
4.3%4.3%-0.1%
WAT_9192025_Monopoly_xInd_xCD_Getting_Cheaper09192025WATWatersMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
11.2%11.2%-4.3%
ISRG_9052025_Monopoly_xInd_xCD_Getting_Cheaper09052025ISRGIntuitive SurgicalMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-4.4%-4.4%-8.0%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for Moderna

Financials

MRNAPFEALNYSRPTCVACACSBMedian
NameModerna Pfizer Alnylam .Sarepta .CureVac Acesis  
Mkt Price26.0124.51481.6722.515.36-24.51
Mkt Cap10.1139.362.52.21.2-10.1
Rev LTM3,05563,8332,3482,482511-2,482
Op Inc LTM-3,27316,663-115-1210--1
FCF LTM-3,50012,438-75-454196--75
FCF 3Y Avg-2,7449,304-184-505-153--184
CFO LTM-2,69715,188-45-301204--45
CFO 3Y Avg-2,05512,584-131-395-111--131

Growth & Margins

MRNAPFEALNYSRPTCVACACSBMedian
NameModerna Pfizer Alnylam .Sarepta .CureVac Acesis  
Rev Chg LTM-38.8%13.5%17.2%64.9%675.2%-17.2%
Rev Chg 3Y Avg-48.0%-12.4%40.8%45.0%227.6%-40.8%
Rev Chg Q-38.0%10.3%20.2%68.4%-91.4%-10.3%
QoQ Delta Rev Chg LTM-2.7%2.2%4.4%11.1%-2.5%-2.2%
Op Mgn LTM-107.1%26.1%-4.9%-0.0%41.1%--0.0%
Op Mgn 3Y Avg-65.1%20.2%-27.5%-16.1%-403.2%--27.5%
QoQ Delta Op Mgn LTM11.7%1.8%3.0%5.2%3.3%-3.3%
CFO/Rev LTM-88.3%23.8%-1.9%-12.1%40.0%--1.9%
CFO/Rev 3Y Avg-51.8%18.8%-13.1%-29.1%-353.8%--29.1%
FCF/Rev LTM-114.6%19.5%-3.2%-18.3%38.4%--3.2%
FCF/Rev 3Y Avg-67.2%13.8%-16.6%-35.5%-442.0%--35.5%

Valuation

MRNAPFEALNYSRPTCVACACSBMedian
NameModerna Pfizer Alnylam .Sarepta .CureVac Acesis  
Mkt Cap10.1139.362.52.21.2-10.1
P/S3.32.226.60.92.4-2.4
P/EBIT-3.410.4-297.2-440.65.5--3.4
P/E-3.513.0-231.6-38.16.2--3.5
P/CFO-3.79.2-1,384.6-7.35.9--3.7
Total Yield-28.8%12.9%-0.4%-2.6%16.0%--0.4%
Dividend Yield0.0%5.2%0.0%0.0%0.0%-0.0%
FCF Yield 3Y Avg-14.3%5.7%-0.8%-12.0%-13.7%--12.0%
D/E0.10.40.00.60.0-0.1
Net D/E-0.40.3-0.00.3-0.3--0.0

Returns

MRNAPFEALNYSRPTCVACACSBMedian
NameModerna Pfizer Alnylam .Sarepta .CureVac Acesis  
1M Rtn2.2%1.5%6.5%21.5%0.2%-2.2%
3M Rtn-16.8%0.2%50.3%59.9%-0.6%-0.2%
6M Rtn5.2%14.8%105.4%-58.2%71.8%-14.8%
12M Rtn-51.9%-10.2%62.8%-82.3%91.4%--10.2%
3Y Rtn-78.9%-33.0%150.9%-79.9%-26.9%--33.0%
1M Excs Rtn1.7%1.0%6.0%21.1%-0.3%-1.7%
3M Excs Rtn-21.7%-4.7%44.6%63.3%-6.4%--4.7%
6M Excs Rtn-20.9%-11.4%79.2%-84.3%45.6%--11.4%
12M Excs Rtn-69.2%-25.5%53.0%-96.4%76.2%--25.5%
3Y Excs Rtn-166.4%-117.5%73.9%-166.2%-116.9%--117.5%

Financials

Segment Financials

Revenue by Segment

$ Mil20242023202220212020
COVID-196,67118,435   
Other revenue177828   
Respiratory syncytial virus (RSV)00   
Collaboration revenue  617448
Grant revenue  73552912
Net Product Sales  17,675200 
Total6,84819,26318,47180360


Price Behavior

Short Interest

Short Interest: As Of Date9302025
Short Interest: Shares Quantity64,337,988
Short Interest: % Change Since 91520251.6%
Average Daily Volume11,546,655
Days-to-Cover Short Interest5.57
Basic Shares Quantity388,000,000
Short % of Basic Shares16.6%

Earnings Returns History

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 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/1/2025-6.6%-10.0%-18.5%
5/1/2025-5.3%-15.7%-6.9%
2/14/20253.4%11.3%8.7%
11/7/2024-3.0%-18.7%-14.2%
8/1/2024-21.0%-31.6%-34.9%
5/2/202412.7%9.4%27.9%
2/22/202413.5%11.3%18.8%
11/2/2023-6.5%-6.4%4.8%
...
SUMMARY STATS   
# Positive111112
# Negative111110
Median Positive8.7%8.9%18.9%
Median Negative-4.5%-10.0%-12.8%
Max Positive22.7%33.2%93.2%
Max Negative-21.0%-33.8%-34.9%

SEC Filings

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Report DateFiling DateFiling
6302025801202510-Q 6/30/2025
3312025501202510-Q 3/31/2025
12312024221202510-K 12/31/2024
93020241107202410-Q 9/30/2024
6302024801202410-Q 6/30/2024
3312024502202410-Q 3/31/2024
12312023223202410-K 12/31/2023
93020231103202310-Q 9/30/2023
6302023803202310-Q 6/30/2023
3312023504202310-Q 3/31/2023
12312022224202310-K 12/31/2022
93020221103202210-Q 9/30/2022
6302022803202210-Q 6/30/2022
3312022504202210-Q 3/31/2022
12312021225202210-K 12/31/2021
93020211104202110-Q 9/30/2021

Insider Activity

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