Moderna (MRNA)
Market Price (10/19/2025): $26.18 | Market Cap: $10.2 BilSector: Health Care | Industry: Biotechnology
Moderna (MRNA)
Market Price (10/19/2025): $26.18Market Cap: $10.2 BilSector: Health CareIndustry: Biotechnology
Investment Highlights
Why It Matters
Which of these 2 stories sounds closer for this stock?
1. Generates cash flow
The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.
2. Riding a trend
Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow
Cash is significant % of market capNet D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -44% | Weak multi-year price returns2Y Excs Rtn is -128%, 3Y Excs Rtn is -166% | Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -3.3 Bil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -107% |
Valuation becoming less expensiveP/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -30% | Meaningful short interestShort Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 17% | Weak revenue growthRev Chg LTMRevenue Change % Last Twelve Months (LTM) is -39%, Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -48%, Rev Chg QQuarterly Revenue Change % is -38% |
Not cash flow generativeCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -88%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -115% | ||
Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -33% |
Cash is significant % of market capNet D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -44% |
Valuation becoming less expensiveP/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -30% |
Weak multi-year price returns2Y Excs Rtn is -128%, 3Y Excs Rtn is -166% |
Meaningful short interestShort Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 17% |
Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -3.3 Bil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -107% |
Weak revenue growthRev Chg LTMRevenue Change % Last Twelve Months (LTM) is -39%, Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -48%, Rev Chg QQuarterly Revenue Change % is -38% |
Not cash flow generativeCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -88%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -115% |
Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -33% |
Market Valuation & Key Metrics
MRNA Stock
Return vs. Risk
Price Returns Compared
2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total [1] | |
---|---|---|---|---|---|---|---|
Returns | |||||||
MRNA Return | 434% | 143% | -29% | -45% | -58% | -37% | 33% |
Peers Return | 11% | -2% | -2% | -29% | 7% | 19% | -4% |
S&P 500 Return | 16% | 27% | -19% | 24% | 23% | 13% | 106% |
Monthly Win Rates [3] | |||||||
MRNA Win Rate | 75% | 67% | 50% | 25% | 42% | 44% | |
Peers Win Rate | 46% | 54% | 50% | 40% | 40% | 50% | |
S&P 500 Win Rate | 58% | 75% | 42% | 67% | 75% | 67% | |
Max Drawdowns [4] | |||||||
MRNA Max Drawdown | -9% | 0% | -54% | -61% | -63% | -43% | |
Peers Max Drawdown | -20% | -33% | -43% | -41% | -21% | -34% | |
S&P 500 Max Drawdown | -31% | -1% | -25% | -1% | -2% | -15% | |
[1] Cumulative total returns since the beginning of 2020
[2] Peers: PFE, ALNY, SRPT, CVAC, ACSB. See MRNA Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 10/17/2025 (YTD)
Downturns Compared
Event | MRNA | S&P 500 |
---|---|---|
2022 Inflation Shock | ||
% Loss | -85.7% | -25.4% |
% Gain to Breakeven | 597.0% | 34.1% |
Time to Breakeven | Not Fully Recovered days | 464 days |
2020 Covid Pandemic | ||
% Loss | -42.7% | -33.9% |
% Gain to Breakeven | 74.5% | 51.3% |
Time to Breakeven | 69 days | 148 days |
2018 Correction | ||
% Loss | -56.7% | -19.8% |
% Gain to Breakeven | 131.2% | 24.7% |
Time to Breakeven | 205 days | 120 days |
How Low Can It Go?
Moderna's stock fell -85.7% during the 2022 Inflation Shock from a high on 8/9/2021. A -85.7% loss requires a 597.0% gain to breakeven.
Preserve Wealth
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Asset Allocation
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Latest Trefis Analyses
Trade Ideas
Select past ideas related to MRNA. For more, see Trefis Trade Ideas.
Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
---|---|---|---|---|---|---|---|
09302025 | ADMA | ADMA Biologics | Dip Buy | DB | P/E OPMDip Buy with Low PE and High MarginBuying dips for companies with tame PE and meaningfully high operating margin | -2.0% | -2.0% | -4.6% |
09302025 | REGN | Regeneron Pharmaceuticals | Dip Buy | DB | P/E OPMDip Buy with Low PE and High MarginBuying dips for companies with tame PE and meaningfully high operating margin | 2.8% | 2.8% | -0.8% |
09262025 | HAE | Haemonetics | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 4.3% | 4.3% | -0.1% |
09192025 | WAT | Waters | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | 11.2% | 11.2% | -4.3% |
09052025 | ISRG | Intuitive Surgical | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | -4.4% | -4.4% | -8.0% |
Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
---|---|---|---|---|---|---|---|
09302025 | ADMA | ADMA Biologics | Dip Buy | DB | P/E OPMDip Buy with Low PE and High MarginBuying dips for companies with tame PE and meaningfully high operating margin | -2.0% | -2.0% | -4.6% |
09302025 | REGN | Regeneron Pharmaceuticals | Dip Buy | DB | P/E OPMDip Buy with Low PE and High MarginBuying dips for companies with tame PE and meaningfully high operating margin | 2.8% | 2.8% | -0.8% |
09262025 | HAE | Haemonetics | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 4.3% | 4.3% | -0.1% |
09192025 | WAT | Waters | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | 11.2% | 11.2% | -4.3% |
09052025 | ISRG | Intuitive Surgical | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | -4.4% | -4.4% | -8.0% |
Research & Analysis
Invest in Strategies
Wealth Management
Peer Comparisons for Moderna
Financials
Median | |
---|---|
Name | |
Mkt Price | 24.51 |
Mkt Cap | 10.1 |
Rev LTM | 2,482 |
Op Inc LTM | -1 |
FCF LTM | -75 |
FCF 3Y Avg | -184 |
CFO LTM | -45 |
CFO 3Y Avg | -131 |
Growth & Margins
Median | |
---|---|
Name | |
Rev Chg LTM | 17.2% |
Rev Chg 3Y Avg | 40.8% |
Rev Chg Q | 10.3% |
QoQ Delta Rev Chg LTM | 2.2% |
Op Mgn LTM | -0.0% |
Op Mgn 3Y Avg | -27.5% |
QoQ Delta Op Mgn LTM | 3.3% |
CFO/Rev LTM | -1.9% |
CFO/Rev 3Y Avg | -29.1% |
FCF/Rev LTM | -3.2% |
FCF/Rev 3Y Avg | -35.5% |
Valuation
Median | |
---|---|
Name | |
Mkt Cap | 10.1 |
P/S | 2.4 |
P/EBIT | -3.4 |
P/E | -3.5 |
P/CFO | -3.7 |
Total Yield | -0.4% |
Dividend Yield | 0.0% |
FCF Yield 3Y Avg | -12.0% |
D/E | 0.1 |
Net D/E | -0.0 |
Returns
Median | |
---|---|
Name | |
1M Rtn | 2.2% |
3M Rtn | 0.2% |
6M Rtn | 14.8% |
12M Rtn | -10.2% |
3Y Rtn | -33.0% |
1M Excs Rtn | 1.7% |
3M Excs Rtn | -4.7% |
6M Excs Rtn | -11.4% |
12M Excs Rtn | -25.5% |
3Y Excs Rtn | -117.5% |
Comparison Analyses
Returns Analyses
Earnings Returns History
Expand for MoreForward Returns | |||
---|---|---|---|
Earnings Date | 1D Returns | 5D Returns | 21D Returns |
8/1/2025 | -6.6% | -10.0% | -18.5% |
5/1/2025 | -5.3% | -15.7% | -6.9% |
2/14/2025 | 3.4% | 11.3% | 8.7% |
11/7/2024 | -3.0% | -18.7% | -14.2% |
8/1/2024 | -21.0% | -31.6% | -34.9% |
5/2/2024 | 12.7% | 9.4% | 27.9% |
2/22/2024 | 13.5% | 11.3% | 18.8% |
11/2/2023 | -6.5% | -6.4% | 4.8% |
... | |||
SUMMARY STATS | |||
# Positive | 11 | 11 | 12 |
# Negative | 11 | 11 | 10 |
Median Positive | 8.7% | 8.9% | 18.9% |
Median Negative | -4.5% | -10.0% | -12.8% |
Max Positive | 22.7% | 33.2% | 93.2% |
Max Negative | -21.0% | -33.8% | -34.9% |
SEC Filings
Expand for MoreReport Date | Filing Date | Filing |
---|---|---|
6302025 | 8012025 | 10-Q 6/30/2025 |
3312025 | 5012025 | 10-Q 3/31/2025 |
12312024 | 2212025 | 10-K 12/31/2024 |
9302024 | 11072024 | 10-Q 9/30/2024 |
6302024 | 8012024 | 10-Q 6/30/2024 |
3312024 | 5022024 | 10-Q 3/31/2024 |
12312023 | 2232024 | 10-K 12/31/2023 |
9302023 | 11032023 | 10-Q 9/30/2023 |
6302023 | 8032023 | 10-Q 6/30/2023 |
3312023 | 5042023 | 10-Q 3/31/2023 |
12312022 | 2242023 | 10-K 12/31/2022 |
9302022 | 11032022 | 10-Q 9/30/2022 |
6302022 | 8032022 | 10-Q 6/30/2022 |
3312022 | 5042022 | 10-Q 3/31/2022 |
12312021 | 2252022 | 10-K 12/31/2021 |
9302021 | 11042021 | 10-Q 9/30/2021 |
Industry Resources
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