Illumina (ILMN)
Market Price (9/13/2025): $95.36 | Market Cap: $15.0 BilSector: Health Care | Industry: Life Sciences Tools & Services
Illumina (ILMN)
Market Price (9/13/2025): $95.36Market Cap: $15.0 BilSector: Health CareIndustry: Life Sciences Tools & Services
Investment Highlights
Attractive yieldTotal YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 8.4%, ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is 3.9%, FCF Yield is 6.9% | Weak multi-year price returns2Y Excs Rtn is -86%, 3Y Excs Rtn is -118% | Weak revenue growthRev Chg LTMRevenue Change % Last Twelve Months (LTM) is -3.3%, Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -3.0%, Rev Chg QQuarterly Revenue Change % is -4.8% |
Attractive operating marginsOp Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 19% | ||
Attractive cash flow generationCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 27%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 24% | ||
Valuation becoming less expensiveP/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -28% | ||
Low stock price volatilityVol 12M is 42% |
Attractive yieldTotal YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 8.4%, ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is 3.9%, FCF Yield is 6.9% |
Attractive operating marginsOp Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 19% |
Attractive cash flow generationCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 27%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 24% |
Valuation becoming less expensiveP/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -28% |
Low stock price volatilityVol 12M is 42% |
Weak multi-year price returns2Y Excs Rtn is -86%, 3Y Excs Rtn is -118% |
Weak revenue growthRev Chg LTMRevenue Change % Last Twelve Months (LTM) is -3.3%, Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -3.0%, Rev Chg QQuarterly Revenue Change % is -4.8% |
Market Valuation
9/13/25 | 2024 | 2023 | 2022 | 2021 | |
---|---|---|---|---|---|
Share Price CYE | $95.36 | $133.63 | $135.32 | $196.50 | $369.72 |
Market Cap CYE ($ Bil) | 15.0 | 21.2 | 21.4 | 30.9 | 56.2 |
Total Debt ($ Bil) | 2.6 | 2.6 | 2.3 | 3.6 | 2.5 |
Total Cash ($ Bil) | 1.2 | 1.2 | 1.1 | 2.0 | 1.3 |
Enterprise Value ($ Bil) | 16.4 | 23.8 | 23.7 | 34.5 | 58.7 |
Valuation Ratios | |||||
P/S TTM | 3.5 | 4.9 | 4.8 | 6.7 | 12.2 |
P/EBIT TTM | 9.9 | -19.7 | -20.6 | -7.2 | 58.7 |
P/E TTM | 11.9 | -17.4 | -18.4 | -7.0 | 72.8 |
Sector Ratios | |||||
P/S TTM (Sector) | 3.8 | 3.6 | 4.1 | 4.5 | 7.3 |
P/EBIT TTM (Sector) | -1.6 | -1.3 | -1.4 | -1.3 | -2.9 |
P/E TTM (Sector) | -1.9 | -1.6 | -1.5 | -1.4 | -2.9 |
9/13/25 | 2024 | 2023 | |
---|---|---|---|
Share Price CYE | $95.36 | $133.63 | $135.32 |
Market Cap CYE ($ Bil) | 15.0 | 21.2 | 21.4 |
Total Debt ($ Bil) | 2.6 | 2.6 | 2.3 |
Total Cash ($ Bil) | 1.2 | 1.2 | 1.1 |
Enterprise Value ($ Bil) | 16.4 | 23.8 | 23.7 |
Valuation Ratios | |||
P/S TTM | 3.5 | 4.9 | 4.8 |
P/EBIT TTM | 9.9 | -19.7 | -20.6 |
P/E TTM | 11.9 | -17.4 | -18.4 |
Sector Ratios | |||
P/S TTM (Sector) | 3.8 | 3.6 | 4.1 |
P/EBIT TTM (Sector) | -1.6 | -1.3 | -1.4 |
P/E TTM (Sector) | -1.9 | -1.6 | -1.5 |
Business Description
Illumina, Inc. provides sequencing and array-based solutions for genetic and genomic analysis. Its products and services serve customers in a range of markets enabling the adoption of genomic solutions in research and clinical settings for applications in the life sciences, oncology, reproductive health, agriculture, and other emerging segments.
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Price Returns Compared
Expand for Detailed View2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total [1] | |
---|---|---|---|---|---|---|---|
Returns | |||||||
ILMN Return | 12% | 3% | -47% | -31% | -1% | -26% | -69% |
Peers Return | 44% | 38% | -27% | 10% | -20% | -16% | 7% |
S&P 500 Return | 16% | 27% | -19% | 24% | 23% | 12% | 101% |
[1] Cumulative total returns since the beginning of 2020
[2] Peers: TMO, A, BRKR, TXG, DHR. See ILMN Returns vs. Peers.
[3] 2025 data is for the year up to 9/12/2025 (YTD)
Latest Trefis Analyses
Research & Analysis
Invest in Strategies
Wealth Management
Peer Comparisons for Illumina
Financials
Median | |
---|---|
Name | |
Mkt Price | 109.18 |
Mkt Cap | 25.0 |
Rev LTM | 5,536 |
Op Inc LTM | 1,134 |
FCF LTM | 1,056 |
FCF 3Y Avg | 847 |
CFO LTM | 1,324 |
CFO 3Y Avg | 1,145 |
Growth & Margins
Median | |
---|---|
Name | |
Rev Chg LTM | 2.0% |
Rev Chg 3Y Avg | 0.6% |
Rev Chg Q | 3.2% |
QoQ Delta Rev Chg LTM | 0.8% |
Op Mgn LTM | 18.3% |
Op Mgn 3Y Avg | 15.5% |
QoQ Delta Op Mgn LTM | -0.3% |
CFO/Rev LTM | 19.8% |
CFO/Rev 3Y Avg | 16.8% |
FCF/Rev LTM | 15.2% |
FCF/Rev 3Y Avg | 12.2% |
Valuation
Median | |
---|---|
Name | |
Mkt Cap | 25.0 |
P/S | 3.8 |
P/EBIT | 22.4 |
P/E | 28.1 |
P/CFO | 23.4 |
Total Yield | 3.1% |
Dividend Yield | 0.0% |
FCF Yield 3Y Avg | 3.1% |
D/E | 0.2 |
Net D/E | 0.1 |
Returns
Median | |
---|---|
Name | |
1M Rtn | -6.4% |
3M Rtn | 7.5% |
6M Rtn | -3.0% |
12M Rtn | -27.3% |
3Y Rtn | -33.3% |
1M Excs Rtn | -8.2% |
3M Excs Rtn | -3.0% |
6M Excs Rtn | -19.3% |
12M Excs Rtn | -46.7% |
3Y Excs Rtn | -98.6% |
Comparison Analyses
Segment Financials
Revenue by Segment
$ Mil | 2024 | 2023 | 2022 | 2021 | 2020 |
---|---|---|---|---|---|
Core Illumina | 4,438 | 4,553 | 4,519 | 3,239 | 3,543 |
GRAIL | 93 | 55 | 12 | ||
Eliminations | -26 | -24 | -5 | -1 | |
Helix | 1 | ||||
Total | 4,505 | 4,584 | 4,526 | 3,239 | 3,543 |
$ Mil | 2024 | 2023 | 2022 | 2021 | 2020 |
---|---|---|---|---|---|
Core Illumina | 552 | 481 | 808 | 580 | 1,008 |
Eliminations | 0 | -24 | |||
GRAIL | -931 | ||||
Helix | 1 | ||||
Total | 552 | 481 | -123 | 580 | 985 |
$ Mil | 2024 | 2023 | 2022 | 2021 | 2020 |
---|---|---|---|---|---|
Core Illumina | 7,585 | 7,316 | |||
Total | 7,585 | 7,316 |
Returns Analyses
Earnings Returns History
Expand for MoreForward Returns | |||
---|---|---|---|
Earnings Date | 1D Returns | 5D Returns | 21D Returns |
7/31/2025 | -7.8% | -7.0% | -2.7% |
5/8/2025 | -4.8% | 1.7% | 6.8% |
1/14/2025 | -5.4% | -2.0% | -28.2% |
11/4/2024 | 1.0% | -1.3% | -7.2% |
8/6/2024 | 4.1% | 2.9% | 11.5% |
5/2/2024 | -4.9% | -10.2% | -16.6% |
2/8/2024 | -3.8% | 1.9% | -3.0% |
11/9/2023 | -8.0% | -11.0% | 10.0% |
... | |||
SUMMARY STATS | |||
# Positive | 6 | 7 | 8 |
# Negative | 18 | 17 | 16 |
Median Positive | 2.5% | 3.8% | 7.7% |
Median Negative | -6.2% | -8.1% | -8.7% |
Max Positive | 7.9% | 13.3% | 24.9% |
Max Negative | -14.6% | -25.5% | -28.2% |
SEC Filings
Expand for MoreReport Date | Filing |
---|---|
6302025 | 10-Q 6/29/2025 |
3312025 | 10-Q 3/30/2025 |
12312024 | 10-K 12/29/2024 |
9302024 | 10-Q 9/29/2024 |
6302024 | 10-Q 6/30/2024 |
3312024 | 10-Q 3/31/2024 |
12312023 | 10-K 12/31/2023 |
9302023 | 10-Q 10/1/2023 |
6302023 | 10-Q 7/2/2023 |
3312023 | 10-Q 4/2/2023 |
12312022 | 10-K 1/1/2023 |
9302022 | 10-Q 10/2/2022 |
6302022 | 10-Q 7/3/2022 |
3312022 | 10-Q 4/3/2022 |
12312021 | 10-K 1/2/2022 |
9302021 | 10-Q 10/3/2021 |
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