Tearsheet

Editas Medicine (EDIT)


Market Price (10/23/2025): $3.58 | Market Cap: $302.2 Mil
Sector: Health Care | Industry: Biotechnology

Editas Medicine (EDIT)


Market Price (10/23/2025): $3.58
Market Cap: $302.2 Mil
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Which of these 2 stories sounds closer for this stock?

1. Generates cash flow

The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.

2. Riding a trend

Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow


0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -52%
Weak multi-year price returns
2Y Excs Rtn is -101%, 3Y Excs Rtn is -152%
Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -161 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -413%
1   Stock price has recently run up significantly
6M Rtn6 month market price return is 129%
2   Weak revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is -42%
3   Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -518%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -527%
4   Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -83%
5   High stock price volatility
Vol 12M is 140%
0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -52%
1 Weak multi-year price returns
2Y Excs Rtn is -101%, 3Y Excs Rtn is -152%
2 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -161 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -413%
3 Stock price has recently run up significantly
6M Rtn6 month market price return is 129%
4 Weak revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is -42%
5 Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -518%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -527%
6 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -83%
7 High stock price volatility
Vol 12M is 140%

Market Valuation & Key Metrics

EDIT Stock


Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
EDIT Return137%-62%-67%14%-87%181%-87%
Peers Return96%14%-65%-9%-59%80%-47%
S&P 500 Return16%27%-19%24%23%14%106%

Monthly Win Rates [3]
EDIT Win Rate50%17%33%50%17%89% 
Peers Win Rate48%32%31%40%37%56% 
S&P 500 Win Rate58%75%42%67%75%67% 

Max Drawdowns [4]
EDIT Max Drawdown-50%-62%-69%-30%-88%-23% 
Peers Max Drawdown-37%-20%-68%-39%-60%-30% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: CRSP, NTLA, CRBU, DTIL, ACSB. See EDIT Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 10/22/2025 (YTD)

How Low Can It Go

Unique KeyEventEDITS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-93.1%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven1349.3%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-54.6%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven120.3%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven98 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-58.7%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven142.3%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven719 days120 days

Compare to CRSP, NTLA, CRBU, DTIL, ACSB


In The Past

Editas Medicine's stock fell -93.1% during the 2022 Inflation Shock from a high on 1/8/2021. A -93.1% loss requires a 1349.3% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth over time.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Editas Medicine (EDIT)

Better Bets than Editas Medicine (EDIT)

Latest Trefis Analyses

Trade Ideas

Select past ideas related to EDIT. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
ADMA_9302025_Dip_Buyer_ValueBuy09302025ADMAADMA BiologicsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
0.4%0.4%-4.6%
REGN_9302025_Dip_Buyer_ValueBuy09302025REGNRegeneron PharmaceuticalsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
3.0%3.0%-0.8%
HAE_9262025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG09262025HAEHaemoneticsDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
6.3%6.3%-0.1%
WAT_9192025_Monopoly_xInd_xCD_Getting_Cheaper09192025WATWatersMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
16.1%16.1%-4.3%
ISRG_9052025_Monopoly_xInd_xCD_Getting_Cheaper09052025ISRGIntuitive SurgicalMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-0.9%-0.9%-8.0%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
ADMA_9302025_Dip_Buyer_ValueBuy09302025ADMAADMA BiologicsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
0.4%0.4%-4.6%
REGN_9302025_Dip_Buyer_ValueBuy09302025REGNRegeneron PharmaceuticalsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
3.0%3.0%-0.8%
HAE_9262025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG09262025HAEHaemoneticsDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
6.3%6.3%-0.1%
WAT_9192025_Monopoly_xInd_xCD_Getting_Cheaper09192025WATWatersMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
16.1%16.1%-4.3%
ISRG_9052025_Monopoly_xInd_xCD_Getting_Cheaper09052025ISRGIntuitive SurgicalMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-0.9%-0.9%-8.0%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for Editas Medicine

Financials

EDITCRSPNTLACRBUDTILACSBMedian
NameEditas M.CRISPR T.Intellia.Caribou .Precisio.Acesis  
Mkt Price3.5766.5224.582.536.93-6.93
Mkt Cap0.35.82.50.20.1-0.3
Rev LTM39355391-35
Op Inc LTM-161-552-512-155-90--161
FCF LTM-205-351-422-136-64--205
FCF 3Y Avg-182-280-396-122-60--182
CFO LTM-201-325-419-133-64--201
CFO 3Y Avg-177-263-387-115-58--177

Growth & Margins

EDITCRSPNTLACRBUDTILACSBMedian
NameEditas M.CRISPR T.Intellia.Caribou .Precisio.Acesis  
Rev Chg LTM-42.0%-82.5%15.0%-72.5%-98.6%--72.5%
Rev Chg 3Y Avg55.3%380.7%6.2%22.1%4.6%-22.1%
Rev Chg Q597.5%-104.8%-23.0%-100.0%-40.9%
QoQ Delta Rev Chg LTM8.6%0.0%16.0%-8.0%-97.5%-0.0%
Op Mgn LTM-413.4%-1,578.5%-968.7%-1,704.4%-7,145.9%--1,578.5%
Op Mgn 3Y Avg-616.5%-678.1%-991.9%-993.9%-2,415.7%--991.9%
QoQ Delta Op Mgn LTM164.9%-223.0%218.7%-55.6%-7,059.7%--55.6%
CFO/Rev LTM-517.6%-927.9%-791.9%-1,459.4%-5,068.8%--927.9%
CFO/Rev 3Y Avg-538.7%-396.8%-766.0%-819.3%-1,746.9%--766.0%
FCF/Rev LTM-526.8%-1,001.6%-798.0%-1,488.5%-5,107.9%--1,001.6%
FCF/Rev 3Y Avg-552.8%-426.2%-785.0%-860.8%-1,762.7%--785.0%

Valuation

EDITCRSPNTLACRBUDTILACSBMedian
NameEditas M.CRISPR T.Intellia.Caribou .Precisio.Acesis  
Mkt Cap0.35.82.50.20.1-0.3
P/S7.7165.548.225.860.7-48.2
P/EBIT-1.3-10.5-5.0-1.5-1.0--1.5
P/E-1.3-12.4-5.3-1.4-1.0--1.4
P/CFO-1.5-17.8-6.1-1.8-1.2--1.8
Total Yield-78.6%-8.1%-18.8%-69.8%-102.2%--69.8%
Dividend Yield0.0%0.0%0.0%0.0%0.0%-0.0%
FCF Yield 3Y Avg-61.3%-6.4%-23.9%-81.1%-105.8%--61.3%
D/E0.10.00.00.10.4-0.1
Net D/E-0.5-0.3-0.1-0.7-0.4--0.4

Returns

EDITCRSPNTLACRBUDTILACSBMedian
NameEditas M.CRISPR T.Intellia.Caribou .Precisio.Acesis  
1M Rtn19.0%7.1%42.4%31.1%42.6%-31.1%
3M Rtn3.2%-2.4%72.6%2.0%40.3%-3.2%
6M Rtn128.8%72.6%203.8%200.4%22.0%-128.8%
12M Rtn8.5%38.5%16.6%27.8%-21.1%-16.6%
3Y Rtn-69.6%30.8%-51.1%-73.8%-83.5%--69.6%
1M Excs Rtn18.0%8.8%43.3%35.4%41.4%-35.4%
3M Excs Rtn4.2%-4.6%87.1%1.5%33.3%-4.2%
6M Excs Rtn104.2%48.0%179.2%175.7%-2.6%-104.2%
12M Excs Rtn-8.0%21.7%2.4%12.3%-36.7%-2.4%
3Y Excs Rtn-152.3%-64.1%-137.1%-155.2%-165.5%--152.3%

Financials

Segment Financials

Revenue by Segment

$ Mil20242023202220212020
Business of developing and commercializing genome editing technology7820269121
Total7820269121


Price Behavior

Short Interest

Short Interest: As Of Date9302025
Short Interest: Shares Quantity7,456,270
Short Interest: % Change Since 9152025-1.4%
Average Daily Volume3,165,097
Days-to-Cover Short Interest2.36
Basic Shares Quantity84,412,200
Short % of Basic Shares8.8%

Earnings Returns History

Expand for More

 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/12/202534.5%14.8%18.3%
5/12/2025-2.6%-3.2%31.8%
1/13/2025-7.9%-3.2%-6.3%
10/22/2024-12.5%-13.3%-34.0%
8/7/2024-12.2%-14.7%-25.4%
5/8/2024-11.4%0.0%-4.4%
2/28/202424.9%3.2%-16.0%
11/3/202318.2%11.9%57.2%
...
SUMMARY STATS   
# Positive131210
# Negative101113
Median Positive9.5%9.4%27.6%
Median Negative-6.1%-5.4%-17.3%
Max Positive34.5%45.1%58.3%
Max Negative-12.5%-15.9%-34.0%

SEC Filings

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Report DateFiling DateFiling
6302025812202510-Q 6/30/2025
3312025512202510-Q 3/31/2025
12312024305202510-K 12/31/2024
93020241104202410-Q 9/30/2024
6302024807202410-Q 6/30/2024
3312024508202410-Q 3/31/2024
12312023228202410-K 12/31/2023
93020231103202310-Q 9/30/2023
6302023802202310-Q 6/30/2023
3312023505202310-Q 3/31/2023
12312022222202310-K 12/31/2022
93020221102202210-Q 9/30/2022
6302022803202210-Q 6/30/2022
3312022504202210-Q 3/31/2022
12312021224202210-K 12/31/2021
93020211109202110-Q 9/30/2021

Insider Activity

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 OwnerTitleFiling DateActionPriceSharesTransacted
Value
Value of
Held Shares
Form
0Burkly LindaEVP, CHIEF SCIENTIFIC OFFICER9042025Sell2.607101,843180,403Form
1Parison AmySVP, Chief Financial Officer9042025Sell2.604581,18942,496Form
2O'Neill Gilmore NeilCEO9042025Sell2.605,59214,517713,123Form
3Parison AmySVP, Chief Financial Officer8082025Sell2.586791,75243,414Form
4Parison AmySVP, Chief Financial Officer6042025Sell1.7244676930,180Form