Editas Medicine (EDIT)
Market Price (3/15/2026): $2.46 | Market Cap: $239.5 MilSector: Health Care | Industry: Biotechnology
Editas Medicine (EDIT)
Market Price (3/15/2026): $2.46Market Cap: $239.5 MilSector: Health CareIndustry: Biotechnology
Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.
| Cash is significant % of market capNet D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -54% | Weak multi-year price returns2Y Excs Rtn is -106%, 3Y Excs Rtn is -142% | Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -99 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -245% |
| Megatrend and thematic driversMegatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Gene Editing & Therapy, and Targeted Therapies. | Meaningful short interestShort Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 12% | Weak revenue growthRev Chg QQuarterly Revenue Change % is -19% |
| Significant share based compensationSBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 25% | ||
| Not cash flow generativeCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -408%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -409% | ||
| Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -72% |
| Cash is significant % of market capNet D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -54% |
| Megatrend and thematic driversMegatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Gene Editing & Therapy, and Targeted Therapies. |
| Weak multi-year price returns2Y Excs Rtn is -106%, 3Y Excs Rtn is -142% |
| Meaningful short interestShort Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 12% |
| Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -99 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -245% |
| Weak revenue growthRev Chg QQuarterly Revenue Change % is -19% |
| Significant share based compensationSBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 25% |
| Not cash flow generativeCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -408%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -409% |
| Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -72% |
Qualitative Assessment
AI Analysis | Feedback
1. Improved Financial Stability and Extended Cash Runway Offset by Restructuring Costs.
Editas Medicine significantly narrowed its net loss for the fourth quarter of 2025 to $5.6 million, or $0.06 per share, a substantial improvement from a net loss of $45.4 million, or $0.55 per share, in the same period of 2024. For the full year 2025, the company's net loss decreased by 32% to $160.1 million. This financial improvement was primarily driven by reduced research and development (R&D) and general and administrative (G&A) expenses due to the discontinuation of the reni-cel program. The company also reported a robust cash position of $146.6 million as of December 31, 2025, providing a projected cash runway into the third quarter of 2027. However, these positive financial developments were tempered by increased restructuring and impairment charges, which rose to $60.7 million in 2025 from $12.2 million in 2024, associated with winding down prior programs and workforce reductions.
2. Early-Stage Clinical Progress for Lead Candidate EDIT-401 with Future Milestones.
The company's lead in vivo gene editing candidate, EDIT-401, targeting heterozygous familial hypercholesterolemia (HeFH), demonstrated promising preclinical results, achieving over 90% mean LDL-C reduction in non-human primate studies. Editas Medicine remains on track to submit an Investigational New Drug (IND)/Clinical Trial Application (CTA) for EDIT-401 by mid-2026, initiate its first-in-human clinical trial later in 2026, and anticipates early human proof-of-concept data by year-end 2026. While these advancements are positive and provide a clear development timeline, the candidate is still in early clinical stages, meaning significant clinical and regulatory hurdles remain, contributing to a cautious investor stance.
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Stock Movement Drivers
Fundamental Drivers
The 1.2% change in EDIT stock from 11/30/2025 to 3/14/2026 was primarily driven by a 25.2% change in the company's P/S Multiple.| (LTM values as of) | 11302025 | 3142026 | Change |
|---|---|---|---|
| Stock Price ($) | 2.41 | 2.44 | 1.2% |
| Change Contribution By: | |||
| Total Revenues ($ Mil) | 46 | 41 | -12.6% |
| P/S Multiple | 4.7 | 5.9 | 25.2% |
| Shares Outstanding (Mil) | 90 | 97 | -7.5% |
| Cumulative Contribution | 1.2% |
Market Drivers
11/30/2025 to 3/14/2026| Return | Correlation | |
|---|---|---|
| EDIT | 1.2% | |
| Market (SPY) | -3.1% | 36.1% |
| Sector (XLV) | -5.0% | 35.7% |
Fundamental Drivers
The -5.1% change in EDIT stock from 8/31/2025 to 3/14/2026 was primarily driven by a -13.3% change in the company's Shares Outstanding (Mil).| (LTM values as of) | 8312025 | 3142026 | Change |
|---|---|---|---|
| Stock Price ($) | 2.57 | 2.44 | -5.1% |
| Change Contribution By: | |||
| Total Revenues ($ Mil) | 39 | 41 | 4.2% |
| P/S Multiple | 5.6 | 5.9 | 5.1% |
| Shares Outstanding (Mil) | 84 | 97 | -13.3% |
| Cumulative Contribution | -5.1% |
Market Drivers
8/31/2025 to 3/14/2026| Return | Correlation | |
|---|---|---|
| EDIT | -5.1% | |
| Market (SPY) | 3.0% | 30.2% |
| Sector (XLV) | 9.5% | 28.0% |
Fundamental Drivers
The 27.1% change in EDIT stock from 2/28/2025 to 3/14/2026 was primarily driven by a 128.6% change in the company's P/S Multiple.| (LTM values as of) | 2282025 | 3142026 | Change |
|---|---|---|---|
| Stock Price ($) | 1.92 | 2.44 | 27.1% |
| Change Contribution By: | |||
| Total Revenues ($ Mil) | 62 | 41 | -34.4% |
| P/S Multiple | 2.6 | 5.9 | 128.6% |
| Shares Outstanding (Mil) | 82 | 97 | -15.3% |
| Cumulative Contribution | 27.1% |
Market Drivers
2/28/2025 to 3/14/2026| Return | Correlation | |
|---|---|---|
| EDIT | 27.1% | |
| Market (SPY) | 12.4% | 40.6% |
| Sector (XLV) | 1.9% | 38.2% |
Fundamental Drivers
The -73.0% change in EDIT stock from 2/28/2023 to 3/14/2026 was primarily driven by a -81.4% change in the company's P/S Multiple.| (LTM values as of) | 2282023 | 3142026 | Change |
|---|---|---|---|
| Stock Price ($) | 9.04 | 2.44 | -73.0% |
| Change Contribution By: | |||
| Total Revenues ($ Mil) | 20 | 41 | 105.6% |
| P/S Multiple | 31.6 | 5.9 | -81.4% |
| Shares Outstanding (Mil) | 69 | 97 | -29.3% |
| Cumulative Contribution | -73.0% |
Market Drivers
2/28/2023 to 3/14/2026| Return | Correlation | |
|---|---|---|
| EDIT | -73.0% | |
| Market (SPY) | 73.4% | 30.1% |
| Sector (XLV) | 23.3% | 27.4% |
Price Returns Compared
| 2021 | 2022 | 2023 | 2024 | 2025 | 2026 | Total [1] | |
|---|---|---|---|---|---|---|---|
| Returns | |||||||
| EDIT Return | -62% | -67% | 14% | -87% | 61% | 30% | -96% |
| Peers Return | 10% | -39% | 9% | -36% | 7% | 13% | -44% |
| S&P 500 Return | 27% | -19% | 24% | 23% | 16% | -1% | 80% |
Monthly Win Rates [3] | |||||||
| EDIT Win Rate | 17% | 33% | 50% | 17% | 67% | 67% | |
| Peers Win Rate | 37% | 42% | 47% | 40% | 57% | 53% | |
| S&P 500 Win Rate | 75% | 42% | 67% | 75% | 67% | 33% | |
Max Drawdowns [4] | |||||||
| EDIT Max Drawdown | -62% | -69% | -30% | -88% | -23% | -19% | |
| Peers Max Drawdown | -25% | -50% | -28% | -40% | -34% | -8% | |
| S&P 500 Max Drawdown | -1% | -25% | -1% | -2% | -15% | -2% | |
[1] Cumulative total returns since the beginning of 2021
[2] Peers: CRSP, NTLA, BEAM, VRTX, CRBU. See EDIT Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 3/13/2026 (YTD)
How Low Can It Go
| Event | EDIT | S&P 500 |
|---|---|---|
| 2022 Inflation Shock | ||
| % Loss | -93.1% | -25.4% |
| % Gain to Breakeven | 1349.3% | 34.1% |
| Time to Breakeven | Not Fully Recovered days | 464 days |
| 2020 Covid Pandemic | ||
| % Loss | -54.6% | -33.9% |
| % Gain to Breakeven | 120.3% | 51.3% |
| Time to Breakeven | 98 days | 148 days |
| 2018 Correction | ||
| % Loss | -58.7% | -19.8% |
| % Gain to Breakeven | 142.3% | 24.7% |
| Time to Breakeven | 719 days | 120 days |
Compare to CRSP, NTLA, BEAM, VRTX, CRBU
In The Past
Editas Medicine's stock fell -93.1% during the 2022 Inflation Shock from a high on 1/8/2021. A -93.1% loss requires a 1349.3% gain to breakeven.
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About Editas Medicine (EDIT)
AI Analysis | Feedback
Moderna for genetic diseases, but using CRISPR gene-editing technology.
An early-stage Intel for the human genome, building foundational CRISPR tools to repair DNA.
The Adobe of human DNA, developing powerful CRISPR tools to precisely edit and correct disease-causing genes.
AI Analysis | Feedback
- EDIT-101: A gene-editing therapy in clinical trials for Leber Congenital Amaurosis 10, an inherited childhood blindness.
- EDIT-102: A gene-editing therapy in development for Usher Syndrome 2A and autosomal dominant retinitis pigmentosa, both affecting vision and sometimes hearing.
- EDIT-301: A gene-editing therapy designed to treat sickle cell disease and transfusion-dependent beta-thalassemia.
- Gene-edited Natural Killer (NK) cell medicines: Therapies under development that modify NK cells to treat solid tumor cancers.
- Alpha-beta T cell therapies: Gene-edited T cell therapies being developed for various cancers.
- Gamma delta T cell therapies: Gene-edited T cell therapies in development for treating different types of cancer.
- Neurological disease therapy (Early Discovery): A therapy in early discovery stages aimed at treating a specific neurological disease.
AI Analysis | Feedback
Editas Medicine (EDIT) is a clinical-stage genome editing company focused on developing genomic medicines. As such, it does not currently sell approved products directly to individuals (patients). Instead, its primary "customers" are other companies with which it forms strategic alliances and research collaborations for the development and potential commercialization of its therapies. These collaborations often involve upfront payments, milestone payments, and future royalties, which represent Editas Medicine's revenue streams from these partners.
Based on the provided information, Editas Medicine's major corporate partners (customers) include:
- Juno Therapeutics, Inc.
- Allergan Pharmaceuticals International Limited
- Asklepios BioPharmaceutical, Inc. (AskBio)
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Trade Ideas
Select ideas related to EDIT.
| Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
|---|---|---|---|---|---|---|---|
| 02282026 | QDEL | QuidelOrtho | Insider | Insider Buys 45DStrong Insider BuyingCompanies with multiple insider buys in the last 45 days | 0.0% | 0.0% | 0.0% |
| 02272026 | CHE | Chemed | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 0.0% | 0.0% | 0.0% |
| 02272026 | LLY | Eli Lilly | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | 0.0% | 0.0% | 0.0% |
| 02202026 | HAE | Haemonetics | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 3.5% | 3.5% | 0.0% |
| 02132026 | IQV | IQVIA | Dip Buy | DB | P/E OPMDip Buy with Low PE and High MarginBuying dips for companies with tame PE and meaningfully high operating margin | 7.1% | 7.1% | -3.0% |
| 03312021 | EDIT | Editas Medicine | Insider | Insider Buys 45DStrong Insider BuyingCompanies with multiple insider buys in the last 45 days | 1.2% | -54.7% | -66.5% |
Research & Analysis
Invest in Strategies
Wealth Management
Peer Comparisons
| Peers to compare with: |
Financials
| Median | |
|---|---|
| Name | |
| Mkt Price | 18.96 |
| Mkt Cap | 2.0 |
| Rev LTM | 54 |
| Op Inc LTM | -265 |
| FCF LTM | -263 |
| FCF 3Y Avg | -218 |
| CFO LTM | -255 |
| CFO 3Y Avg | -209 |
Growth & Margins
| Median | |
|---|---|
| Name | |
| Rev Chg LTM | 12.9% |
| Rev Chg 3Y Avg | 58.2% |
| Rev Chg Q | 9.1% |
| QoQ Delta Rev Chg LTM | 2.1% |
| Op Mgn LTM | -274.6% |
| Op Mgn 3Y Avg | -400.4% |
| QoQ Delta Op Mgn LTM | 127.0% |
| CFO/Rev LTM | -407.8% |
| CFO/Rev 3Y Avg | -409.3% |
| FCF/Rev LTM | -409.3% |
| FCF/Rev 3Y Avg | -420.9% |
Valuation
| Median | |
|---|---|
| Name | |
| Mkt Cap | 2.0 |
| P/S | 18.5 |
| P/EBIT | -2.4 |
| P/E | -2.5 |
| P/CFO | -2.6 |
| Total Yield | -20.2% |
| Dividend Yield | 0.0% |
| FCF Yield 3Y Avg | -20.1% |
| D/E | 0.1 |
| Net D/E | -0.4 |
Returns
| Median | |
|---|---|
| Name | |
| 1M Rtn | 5.4% |
| 3M Rtn | 0.1% |
| 6M Rtn | 8.1% |
| 12M Rtn | 27.7% |
| 3Y Rtn | -45.9% |
| 1M Excs Rtn | 6.4% |
| 3M Excs Rtn | -2.0% |
| 6M Excs Rtn | 2.2% |
| 12M Excs Rtn | 1.4% |
| 3Y Excs Rtn | -120.1% |
Comparison Analyses
Price Behavior
| Market Price | $2.44 | |
| Market Cap ($ Bil) | 0.2 | |
| First Trading Date | 02/03/2016 | |
| Distance from 52W High | -41.2% | |
| 50 Days | 200 Days | |
| DMA Price | $2.06 | $2.55 |
| DMA Trend | up | down |
| Distance from DMA | 18.6% | -4.3% |
| 3M | 1YR | |
| Volatility | 91.2% | 99.0% |
| Downside Capture | 222.50 | 223.12 |
| Upside Capture | 242.63 | 238.83 |
| Correlation (SPY) | 34.7% | 37.8% |
| 1M | 2M | 3M | 6M | 1Y | 3Y | |
|---|---|---|---|---|---|---|
| Beta | 3.57 | 2.49 | 2.61 | 2.09 | 2.10 | 1.98 |
| Up Beta | 4.56 | 5.87 | 5.15 | 1.58 | 1.97 | 1.83 |
| Down Beta | 4.49 | 1.37 | 1.47 | 2.77 | 1.77 | 1.73 |
| Up Capture | 416% | 240% | 229% | 161% | 539% | 572% |
| Bmk +ve Days | 9 | 20 | 31 | 70 | 142 | 431 |
| Stock +ve Days | 10 | 18 | 24 | 55 | 111 | 325 |
| Down Capture | 211% | 170% | 242% | 190% | 156% | 113% |
| Bmk -ve Days | 12 | 21 | 30 | 54 | 109 | 320 |
| Stock -ve Days | 10 | 21 | 34 | 65 | 132 | 409 |
[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
| Annualized Return | Annualized Volatility | Sharpe Ratio | Correlation with EDIT | |
|---|---|---|---|---|
| EDIT | 63.2% | 99.5% | 0.93 | - |
| Sector ETF (XLV) | 5.0% | 17.5% | 0.12 | 38.0% |
| Equity (SPY) | 19.6% | 18.9% | 0.81 | 38.3% |
| Gold (GLD) | 71.9% | 26.3% | 2.05 | 13.3% |
| Commodities (DBC) | 19.3% | 17.3% | 0.89 | 10.9% |
| Real Estate (VNQ) | 6.2% | 16.3% | 0.19 | 34.0% |
| Bitcoin (BTCUSD) | -15.3% | 44.2% | -0.25 | 35.6% |
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Based On 5-Year Data
| Annualized Return | Annualized Volatility | Sharpe Ratio | Correlation with EDIT | |
|---|---|---|---|---|
| EDIT | -42.9% | 93.4% | -0.20 | - |
| Sector ETF (XLV) | 7.5% | 14.5% | 0.33 | 29.8% |
| Equity (SPY) | 13.1% | 17.0% | 0.61 | 37.6% |
| Gold (GLD) | 24.1% | 17.3% | 1.14 | 8.4% |
| Commodities (DBC) | 11.2% | 19.0% | 0.47 | 5.0% |
| Real Estate (VNQ) | 4.8% | 18.8% | 0.16 | 32.8% |
| Bitcoin (BTCUSD) | 6.3% | 56.7% | 0.33 | 25.5% |
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Based On 10-Year Data
| Annualized Return | Annualized Volatility | Sharpe Ratio | Correlation with EDIT | |
|---|---|---|---|---|
| EDIT | -23.5% | 84.2% | 0.05 | - |
| Sector ETF (XLV) | 10.1% | 16.5% | 0.50 | 33.1% |
| Equity (SPY) | 14.5% | 17.9% | 0.70 | 37.3% |
| Gold (GLD) | 14.4% | 15.6% | 0.77 | 5.2% |
| Commodities (DBC) | 8.6% | 17.6% | 0.40 | 9.7% |
| Real Estate (VNQ) | 5.6% | 20.7% | 0.23 | 26.6% |
| Bitcoin (BTCUSD) | 67.4% | 66.8% | 1.07 | 17.8% |
Smart multi-asset allocation framework can stack odds in your favor. Learn How
Returns Analyses
Earnings Returns History
Expand for More| Forward Returns | |||
|---|---|---|---|
| Earnings Date | 1D Returns | 5D Returns | 21D Returns |
| 3/9/2026 | 16.0% | ||
| 11/10/2025 | 2.0% | 5.3% | 5.3% |
| 8/12/2025 | 34.5% | 14.8% | 18.3% |
| 5/12/2025 | -2.6% | -3.2% | 31.8% |
| 1/13/2025 | -7.9% | -3.2% | -6.3% |
| 10/22/2024 | -12.5% | -13.3% | -34.0% |
| 8/7/2024 | -12.2% | -14.7% | -25.4% |
| 5/8/2024 | -11.4% | 0.0% | -4.4% |
| ... | |||
| SUMMARY STATS | |||
| # Positive | 14 | 11 | 10 |
| # Negative | 9 | 11 | 12 |
| Median Positive | 9.7% | 9.2% | 21.1% |
| Median Negative | -5.8% | -5.4% | -17.4% |
| Max Positive | 34.5% | 45.1% | 58.3% |
| Max Negative | -12.5% | -15.9% | -34.0% |
SEC Filings
Expand for More| Report Date | Filing Date | Filing |
|---|---|---|
| 12/31/2025 | 03/09/2026 | 10-K |
| 09/30/2025 | 11/10/2025 | 10-Q |
| 06/30/2025 | 08/12/2025 | 10-Q |
| 03/31/2025 | 05/12/2025 | 10-Q |
| 12/31/2024 | 03/05/2025 | 10-K |
| 09/30/2024 | 11/04/2024 | 10-Q |
| 06/30/2024 | 08/07/2024 | 10-Q |
| 03/31/2024 | 05/08/2024 | 10-Q |
| 12/31/2023 | 02/28/2024 | 10-K |
| 09/30/2023 | 11/03/2023 | 10-Q |
| 06/30/2023 | 08/02/2023 | 10-Q |
| 03/31/2023 | 05/05/2023 | 10-Q |
| 12/31/2022 | 02/22/2023 | 10-K |
| 09/30/2022 | 11/02/2022 | 10-Q |
| 06/30/2022 | 08/03/2022 | 10-Q |
| 03/31/2022 | 05/04/2022 | 10-Q |
Insider Activity
Expand for More| # | Owner | Title | Holding | Action | Filing Date | Price | Shares | Transacted Value | Value of Held Shares | Form |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Burkly, Linda | EVP, CHIEF SCIENTIFIC OFFICER | Direct | Sell | 12042025 | 2.15 | 713 | 1,535 | 148,084 | Form |
| 2 | O'Neill, Gilmore Neil | CEO | Direct | Sell | 12042025 | 2.15 | 5,603 | 12,064 | 579,371 | Form |
| 3 | Parison, Amy | SVP, Chief Financial Officer | Direct | Sell | 12042025 | 2.15 | 461 | 993 | 34,252 | Form |
| 4 | Burkly, Linda | EVP, CHIEF SCIENTIFIC OFFICER | Direct | Sell | 9042025 | 2.60 | 710 | 1,843 | 180,403 | Form |
| 5 | Parison, Amy | SVP, Chief Financial Officer | Direct | Sell | 9042025 | 2.60 | 458 | 1,189 | 42,496 | Form |
Industry Resources
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| SeekingAlpha | ValueLine |
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| CNBC | Etrade |
| MarketWatch | Unusual Whales |
| YCharts | Perplexity Finance |
| FinViz |
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