Tearsheet

Investment Highlights

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Market Valuation

 9/4/252024202320222021
Share Price CYE$100.00$113.95$105.54$150.22$254.43
Market Cap CYE ($ Bil)24.227.025.336.862.2
Total Debt ($ Bil)0.30.30.20.20.3
Total Cash ($ Bil)14.016.816.514.12.1
Enterprise Value ($ Bil)10.427.325.537.062.5
Valuation Ratios     
P/S TTM8.410.06.72.13.3
P/EBIT TTM-70.0-41.221.32.84.2
P/E TTM-70.1-41.227.33.96.1
Sector Ratios     
P/S TTM (Sector)3.84.14.54.56.7
P/EBIT TTM (Sector)4.30.4-1.9-1.2-0.4
P/E TTM (Sector)-1.8-2.2-3.4-2.2-2.3
 9/4/2520242023
Share Price CYE$100.00$113.95$105.54
Market Cap CYE ($ Bil)24.227.025.3
Total Debt ($ Bil)0.30.30.2
Total Cash ($ Bil)14.016.816.5
Enterprise Value ($ Bil)10.427.325.5
Valuation Ratios   
P/S TTM8.410.06.7
P/EBIT TTM-70.0-41.221.3
P/E TTM-70.1-41.227.3
Sector Ratios   
P/S TTM (Sector)3.84.14.5
P/EBIT TTM (Sector)4.30.4-1.9
P/E TTM (Sector)-1.8-2.2-3.4

Business Description

BioNTech SE, a biotechnology company, develops and commercializes immunotherapies for cancer and other infectious diseases. The company is developing FixVac product candidates, including BNT111, which is in Phase II clinical trial for advance melanoma; BNT112 that is in Phase I/IIa clinical trial for prostate cancer; BNT113, which is in Phase II clinical trial to treat HPV+ head and neck cancers; BNT114 that is in Phase I clinical trial for triple negative breast cancer; BNT115, which is in Phase I clinical trial in ovarian cancer; and BNT116, a preclinical stage product for non-small cell lung cancer. It also develops neoantigen specific immunotherapies, such as Autogene cevumeran (BNT122), which is in Phase II clinical trial for first-line melanoma, as well as in Phase 1a/1b clinical trial to treat multiple solid tumors; mRNA intratumoral immunotherapy comprising SAR441000 that is in Phase I clinical trial for solid tumors; and BNT141 and BNT142 that are in Phase I clinical trial to treat multiple solid tumors. Show more

Price Returns Compared

Expand for Detailed View

 202020212022202320242025Total [1]
Returns
BNTX Return141%216%-41%-30%8%-12%253%
Peers Return90%55%6%-15%-6%3%156%
S&P 500 Return16%27%-19%24%23%10%100%

[1] Cumulative total returns since the beginning of 2020
[2] Peers: AMGN, PFE, MRNA, ABBV, GILD.
[3] 2025 data is for the year up to 9/3/2025 (YTD)

Latest Trefis Analyses

Recent Active Movers

Recent Active Movers

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Peer Comparisons for BioNTech

Financials

BNTXAMGNPFEMRNAABBVGILDMedian
NameBioNTech Amgen Pfizer Moderna AbbVie Gilead S. 
Mkt Price-286.9224.9824.19211.92112.71112.71
Mkt Cap-154.4142.09.4374.7140.3142.0
Rev LTM-34,91763,8333,05558,32828,86234,917
Op Inc LTM-8,19216,663-3,27313,69510,79710,797
FCF LTM-10,60512,438-3,50018,2399,36910,605
FCF 3Y Avg-8,5909,304-2,74420,2738,3978,590
CFO LTM-12,01315,188-2,69719,2839,86812,013
CFO 3Y Avg-9,75312,584-2,05521,1548,9499,753

Growth & Margins

BNTXAMGNPFEMRNAABBVGILDMedian
NameBioNTech Amgen Pfizer Moderna AbbVie Gilead S. 
Rev Chg LTM-12.9%13.5%-38.8%6.1%3.8%6.1%
Rev Chg 3Y Avg-10.0%-12.4%-48.0%0.6%1.6%0.6%
Rev Chg Q-9.4%10.3%-38.0%6.6%1.8%6.6%
QoQ Delta Rev Chg LTM-2.3%2.2%-2.7%1.7%0.4%1.7%
Op Mgn LTM-23.5%26.1%-107.1%23.5%37.4%23.5%
Op Mgn 3Y Avg-26.4%20.2%-65.1%27.2%39.2%26.4%
QoQ Delta Op Mgn LTM-1.6%1.8%11.7%1.0%-0.0%1.6%
CFO/Rev LTM-34.4%23.8%-88.3%33.1%34.2%33.1%
CFO/Rev 3Y Avg-32.0%18.8%-51.8%37.5%31.9%31.9%
FCF/Rev LTM-30.4%19.5%-114.6%31.3%32.5%30.4%
FCF/Rev 3Y Avg-28.2%13.8%-67.2%36.0%30.0%28.2%

Valuation

BNTXAMGNPFEMRNAABBVGILDMedian
NameBioNTech Amgen Pfizer Moderna AbbVie Gilead S. 
Mkt Cap-154.4142.09.4374.7140.3142.0
P/S-4.42.23.16.44.94.4
P/EBIT-14.910.6-3.263.617.114.9
P/E-23.313.2-3.299.622.222.2
P/CFO-12.89.4-3.519.414.212.8
Total Yield-7.5%12.7%-30.9%4.0%7.3%7.3%
Dividend Yield-3.2%5.1%0.0%3.0%2.8%3.0%
FCF Yield 3Y Avg-6.2%5.7%-14.3%7.3%8.0%6.2%
D/E-0.40.40.10.20.20.2
Net D/E-0.30.3-0.50.20.10.2

Returns

BNTXAMGNPFEMRNAABBVGILDMedian
NameBioNTech Amgen Pfizer Moderna AbbVie Gilead S. 
1M Rtn--2.6%6.3%-12.4%8.6%-0.4%-0.4%
3M Rtn--0.1%8.8%-13.0%14.2%3.8%3.8%
6M Rtn--6.5%0.6%-20.3%3.8%-0.4%-0.4%
12M Rtn--11.2%-7.8%-68.7%11.8%47.3%-7.8%
3Y Rtn-30.3%-35.6%-82.5%74.1%97.4%30.3%
1M Excs Rtn--5.4%3.5%-15.2%5.7%-3.3%-3.3%
3M Excs Rtn--7.8%0.2%-18.7%6.2%-3.9%-3.9%
6M Excs Rtn--15.8%-11.0%-29.8%-7.7%-11.1%-11.1%
12M Excs Rtn--24.7%-21.7%-83.9%-2.4%33.4%-21.7%
3Y Excs Rtn--24.3%-91.3%-135.8%17.5%45.4%-24.3%

Financials

Segment Financials

Revenue by Segment

$ Mil20242023202220212020
Single Segment3,81917,311   
Direct product sales to customers  3,00721 
Other sales  673324
Research & development revenues from collaborations  103  
Sales to collaboration partners  97161 
Share of collaboration partners’ gross profit and sales milestones  14,829188 
Genentech Inc.   4964
Other   36
Pfizer Inc.   12214
Shanghai Fosun Pharmaceutical (Group) Co., Ltd   5 
Total3,81917,31118,977482109


Price Behavior

Short Interest

Short Interest: As Of Date8152025
Short Interest: Shares Quantity6,315,487
Short Interest: % Change Since 73120254.4%
Average Daily Volume708,083
Days-to-Cover Short Interest8.92
Basic Shares Quantity241,625,000
Short % of Basic Shares2.6%