Market Movers | Winners: BRZE, MYGN, LION | Losers: HBCP, TSAT, ANAB
The S&P 500 rose 0.3% on Tuesday, October 20, while the Nasdaq-100 slipped 0.1% and the Dow Jones Industrial Average climbed 1.0%. The S&P 500 is now down 1.2% over five trading days and down 0.7% over the past month.
Within the Trefis coverage universe, 2,937 stocks rose and 1,149 fell. At the extremes, Braze (BRZE) gained 51.7% and Home Bancorp (HBCP) fell 9.6%.

Tuesday’s Market Winners
The 10 US-listed stocks in the Trefis coverage universe worth at least $300 million with the highest returns on Tuesday:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | BRZE | Braze | 51.7% | 32.9% |
| 2 | MYGN | Myriad Genetics | 31.6% | -9.9% |
| 3 | LION | Lionsgate Studios | 14.4% | 33.1% |
| 4 | SLS | SELLAS Life Sciences | 14.2% | 217.8% |
| 5 | CTNM | Contineum Therapeutics | 13.7% | -26.0% |
| 6 | TRAX | First Tracks Biotherapeutics | 13.7% | n/a |
| 7 | GOSS | Gossamer Bio | 13.6% | n/a |
| 8 | KLRA | Kailera Therapeutics | 12.8% | n/a |
| 9 | KVYO | Klaviyo | 11.9% | -39.6% |
| 10 | EQPT | EquipmentShare.com | 11.8% | n/a |
Tuesday’s Market Losers
And the 10 US-listed stocks in the Trefis coverage universe worth at least $300 million with the lowest returns on Tuesday:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | HBCP | Home Bancorp | -9.6% | 4.4% |
| 2 | TSAT | Telesat | -9.0% | 40.4% |
| 3 | ANAB | AnaptysBio | -7.7% | n/a |
| 4 | EOSE | Eos Energy Enterprises | -7.2% | -85.3% |
| 5 | EMAT | Evolution Metals & Technologies | -7.1% | n/a |
| 6 | GM | General Motors | -6.8% | -4.6% |
| 7 | LGN | Legence | -6.7% | -4.2% |
| 8 | MLI | Mueller Industries | -6.6% | -0.2% |
| 9 | DVA | DaVita | -6.2% | 54.3% |
| 10 | METC | Ramaco Resources | -5.5% | -59.9% |
For A Few Names, Tuesday Extended A Monthly Trend
Braze (BRZE) appears on both the one-day and one-month winners lists. It rose 51.7% on Tuesday and is up 79.4% over the past month; excluding Tuesday, it had already gained 18.3% over the other sessions.
Eos Energy Enterprises (EOSE) added to a longer slide: after Tuesday’s 7.2% decline, the stock is down 58.7% over the past month, and it was already down 55.5% before Tuesday.
The 7.1% decline in Evolution Metals & Technologies (EMAT) on Tuesday was not a one-off: the stock is down 58.3% over the past month, and down 55.1% over the sessions before Tuesday.
Movers Over The Last Week
Widening the window to five trading days, these are the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | BRZE | Braze | 57.5% | 32.9% |
| 2 | IRON | Disc Medicine | 40.4% | 0.1% |
| 3 | MYGN | Myriad Genetics | 35.8% | -9.9% |
| 4 | LQDA | Liquidia | 35.6% | 5.4% |
| 5 | TRAX | First Tracks Biotherapeutics | 30.2% | n/a |
| 6 | ARQT | Arcutis Biotherapeutics | 25.8% | 13.0% |
| 7 | OPK | OPKO Health | 25.8% | 31.7% |
| 8 | VSTM | Verastem | 25.4% | 21.0% |
| 9 | NAUT | Nautilus Biotechnology | 24.4% | 30.8% |
| 10 | INDP | Indaptus Therapeutics | 23.8% | 1.7% |
Losers
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | FMC | FMC | -36.1% | -60.9% |
| 2 | PENG | Penguin Solutions | -28.0% | 187.9% |
| 3 | EOSE | Eos Energy Enterprises | -27.6% | -85.3% |
| 4 | BLZE | Backblaze | -26.7% | 96.8% |
| 5 | RXT | Rackspace Technology | -25.3% | n/a |
| 6 | VICR | Vicor | -23.6% | 86.3% |
| 7 | GEMI | Gemini Space Station | -23.5% | -68.4% |
| 8 | FUN | Six Flags Entertainment | -22.9% | -48.8% |
| 9 | DOCN | DigitalOcean | -22.4% | 106.7% |
| 10 | HPP | Hudson Pacific Properties | -22.0% | -12.5% |
Movers Over The Last Month
And over the last 21 trading days, the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | NAUT | Nautilus Biotechnology | 167.1% | 30.8% |
| 2 | BMBL | Bumble | 108.8% | 66.7% |
| 3 | BRZE | Braze | 79.4% | 32.9% |
| 4 | FIGS | FIGS | 51.3% | 74.8% |
| 5 | PCRX | Pacira BioSciences | 50.9% | 40.6% |
| 6 | CBRL | Cracker Barrel Old Country Store | 49.2% | 168.9% |
| 7 | IOVA | Iovance Biotherapeutics | 45.8% | 444.3% |
| 8 | RXO | RXO | 45.4% | 126.8% |
| 9 | MAZE | Maze Therapeutics | 44.9% | -21.7% |
| 10 | PACB | Pacific Biosciences of California | 44.1% | 4.8% |
Losers
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | EOSE | Eos Energy Enterprises | -58.7% | -85.3% |
| 2 | EMAT | Evolution Metals & Technologies | -58.3% | n/a |
| 3 | CIFR | Cipher Digital | -53.0% | -39.8% |
| 4 | QURE | uniQure | -48.7% | -5.1% |
| 5 | PCT | PureCycle Technologies | -48.3% | -65.9% |
| 6 | FMC | FMC | -47.9% | -60.9% |
| 7 | GEMI | Gemini Space Station | -47.7% | -68.4% |
| 8 | BLSM | BlossomHill Therapeutics | -46.3% | n/a |
| 9 | LQDA | Liquidia | -45.3% | 5.4% |
| 10 | TE | T1 Energy | -44.5% | -63.0% |
The Tape Rewards Attention. It Punishes Reaction
Big daily moves pull hard at both greed and fear, and acting on either, day after day, is how most portfolios end up trailing the index they were trying to beat.
The Trefis High Quality (HQ) Portfolio is built for the opposite reflex: about 30 quality businesses screened for the fundamentals that survive volatile stretches, held with rules instead of reactions. It has a track record of outpacing a benchmark that combines the S&P 500, the S&P MidCap 400, and the Russell 2000. Read the movers daily; trade them rarely.