Small Cap Stocks At 52-Week Highs: Wednesday’s Full List
As of Wednesday, September 30, there are 8 Small Cap US and Canada-listed stocks in the Trefis coverage universe trading at their 52-week highs. Small Cap here means a market value between $2 billion and $10 billion, the upper figure excluded.
At about $9.9 billion in market value, Bruker (BRKR) is the largest company on the list; its stock is up 11.7% over the past month and up 110.6% over the past year. Health Care contributed the most names, 6 of the 8. For context, the S&P 500 is down 0.3% over the past month, including dividends.

Every Name On The List
The table below lists all 8 names this screen surfaced, largest first, with one-day, one-week, one-month and one-year returns:
| Tickers | Market Cap |
1D Return |
1W Return |
1M Return |
1Y Return |
|---|---|---|---|---|---|
| BRKR | $9.9 Bil | 0.4% | 8.5% | 11.7% | 110.6% |
| HNGE | $7.7 Bil | 2.1% | 5.4% | 5.1% | 94.9% |
| IOVA | $6.7 Bil | 2.6% | 45.4% | 81.4% | 564.6% |
| CDNA | $3.3 Bil | 1.5% | 19.7% | 29.7% | 337.4% |
| ATKR | $3.2 Bil | 0.0% | 0.3% | 1.1% | 59.0% |
| PGEN | $3.1 Bil | 6.3% | 15.1% | 23.5% | 135.8% |
| SDGR | $2.3 Bil | 2.4% | 6.2% | 59.2% | 54.9% |
| CNXN | $2.3 Bil | 0.8% | 1.9% | 13.0% | 48.1% |
What Sits Behind The Biggest New Highs?
Bruker (BRKR) grew revenue 1.6% over the last twelve months and earned an operating margin of 7.6%.
Hinge Health (HNGE) grew revenue 49.8% over the last twelve months and earned an operating margin of 13.0%.
Across the list, one-month moves range from +1.1% for Atkore (ATKR) to +81.4% for Iovance Biotherapeutics (IOVA).
The median stock on the list is up 102.7% over the past year.
Before chasing any name on this list, ask what the company itself expects next. Our Guidance Momentum screen surfaces the stocks whose managements just raised their own outlooks.
Strength Is A Clue. It Is Not A Plan
A stock at its 52-week high has momentum on its side, and momentum is a real force. It is also the most crowded signal in the market, and what separates a run that lasts from one that tops is usually the business underneath.
Checking that business, across thousands of names, is how the Trefis High Quality (HQ) Portfolio is assembled: roughly 30 companies that pass the quality screens, rebalanced on rules. It has a track record of outpacing a benchmark that combines the S&P 500, the S&P MidCap 400, and the Russell 2000. Let the highs point; let the discipline decide.